Glycoside Hydrolase Family 13 / Subf 15

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (919); Uniprot accession (380); PDB accession (4); 3D entries (1); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 α-amylase I (AmyI) 3.2.1.1 Aedes aegypti AAA29343.1
AAA29344.1
AAA29345.1
AAB60935.1
O02413
P53354
  15
 α-amylase II (AmyII) 3.2.1.1 Aedes aegypti AAB60934.1 O02652   15
 α-amylase 3.2.1.1 Aedes atropalpus AAA03322.1 Q16924   15
 α-amylase (Amy) (fragment)   Anatalanta aptera AAY88824.1 Q3SCC4   15
 α-amylase (Amy)   Anopheles gambiae AAA29357.1 Q17023   15
 α-amylase 3.2.1.1 Anopheles merus AAA03323.1 Q17059   15
 α-amylase (Amylag1) 3.2.1.1 Anthonomus grandis AAN77138.1
AOG18226.1
Q8I9K6   15
 α-amylase (Amylag2) 3.2.1.1 Anthonomus grandis AAN77139.1 Q8I9K5   15
 ACCB10398   Apis cerana AEY60887.1     15
 α-amylase (LOC406114)   Apis mellifera mellifera AAM20738.1
XP_391983.1
Q8N0N7   15
 α-amylase (Amy) 3.2.1.1 Asterias rubens AAO13755.1 Q8IA45   15
 α-amylase (Amy) (fragment)   Bactrocera oleae AAY88838.1 Q3SCB0   15
 Amy   Bibio marci AAL92553.1 Q86N60   15
 α-amylase (Amy2)   Bibio marci AAO91804.1 Q6Y0Z2   15
 α-amylase (Amy1)   Blaps mucronata AAO14612.1 Q8I9Q7   15
 α-amylase (Amy2) (fragment)   Blaps mucronata AAO17924.1 Q8I9Q1   15
 α-amylase   Blattella germanica ABC68516.1
AGV15452.1
Q2L7A6   15
 α-amylase (bgtg-1) 3.2.1.1 Blattella germanica AAY23288.1 Q2KJQ1   15
 α-amylase (Amy;BmAmy)   Bombyx mori Nanglai ACT64133.1 C7EMF0   15
 C50B6.7   Caenorhabditis elegans Bristol N2 CAB02856.1
NP_506303.1
P91982   15
 α-amylase (Amy) (fragment)   Calliphora vomitoria AAY88830.1 Q3SCB8   15
 α-amylase (Amy) (fragment)   Calliphora vomitoria AAY88831.1 Q3SCB7   15
 α-amylase (Ccam) 3.2.1.1 Callosobruchus chinensis BAB72257.1
BAD83655.1
    15
 alpha amylase   Callosobruchus chinensis ANC73389.1     15
 α-amylase (Amy)   Ceratitis capitata AAO13691.1
AAC47371.1
Q17311
Q8IA48
  15
 Amyrel   Ceratitis capitata AAO13692.1 Q8IA47   15
 α-amylase (Amy) (fragment)   Chaetonerius sp. FM-2005a AAY88823.1 Q3SCC5   15
 α-amylase (Amy) (fragment)   Chaetonerius sp. FM-2005b AAY88832.1 Q3SCB6   15
 Amyrel (fragment)   Chymomyza amoena AAW66449.1     15
 α-amylase (Amy) (fragment)   Coelopa frigida AAY88833.1 Q3SCB5   15
 α-amylase (Amy) (fragment)   Coelopa frigida AAY88834.1 Q3SCB4   15
 alpha amylase   Cosmopolites sordidus AKN63428.1     15
 ORF   Cotesia congregata CAR82255.1 B9W4L8   15
 α-amylase (fragment)   Culex tarsalis ACJ64402.1 B8RJA3   15
 α-amylase 3.2.1.1 Culex tarsalis AAA03350.1 Q23767   15
 α-amylase (Amy) (fragment)   Curtonotidae sp. FM-2005a AAY88835.1 Q3SCB3   15
 α-amylase (Amy) (fragment)   Curtonotidae sp. FM-2005b AAY88836.1 Q3SCB2   15
 α-amylase (Amy) (fragment)   Cypselidae sp. FM-2005 AAY88837.1 Q3SCB1   15
 α-amylase (Amy) (fragment)   Delia radicum AAY88825.1 Q3SCC3   15
 α-amylase (Amy) (fragment)   Delia radicum AAY88826.1 Q3SCC2   15
 α-amylase (Amy) (fragment)   Delia radicum AAY88827.1 Q3SCC1   15
 unknown   Dendroctonus ponderosae AEE61654.1     15
 α-amylase 3.2.1.1 Diabrotica virgifera virgifera AAF20998.1 Q9U406   15
 Amy1   Diatraea saccharalis AAP92665.1 Q7YXU5   15
 Amy3   Diatraea saccharalis AAP97394.1 Q7YXJ3   15
 Amy2   Diatraea saccharalis AAP97393.1 Q7YXJ4   15
 α-amylase (Amy) (fragment)   Diopsidae sp. FM-2005 AAY88839.1 Q3SCA9   15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila acanthoptera 15090-1693.00 AHL43631.1     15
 alpha amylase, partial (fragment)   Drosophila acanthoptera 15090-1693.00 AHL43643.1     15
 Amyrel (fragment)   Drosophila adamsi AAW66433.1     15
 α-amylase (Amy) (fragment)   Drosophila affinis ATLANTA AAN16147.1     15
 amylase related protein (Amyrel)   Drosophila affinis ATLANTA AAN16153.1     15
 Amyrel   Drosophila albirostris AAW64450.1     15
 Amyrel   Drosophila albomicans AAO14605.1 Q8I9R4   15
 amyrel protein, partial (fragment)   Drosophila albomicans CM137 BAR88651.1
BAR88652.1
BAR88653.1
BAR88654.1
BAR88655.1
BAR88656.1
BAR88657.1
BAR88658.1
BAR88659.1
BAR88660.1
BAR88661.1
BAR88662.1
BAR88663.1
BAR88664.1
BAR88665.1
BAR88666.1
BAR88667.1
BAR88668.1
BAR88669.1
BAR88670.1
BAR88671.1
BAR88672.1
BAR88673.1
BAR88674.1
BAR88675.1
BAR88676.1
BAR88677.1
BAR88678.1
BAR88679.1
BAR88680.1
BAR88681.1
BAR88682.1
    15
 amylase-related protein (Amyrel) (fragment)   Drosophila ambigua AAN16193.1     15
 α-amylase (Amy) (fragment)   Drosophila ambigua ECOSSE AAN16140.1     15
 Amyrel (fragment)   Drosophila americana AAW66434.1     15
 Amyrel (fragment)   Drosophila americana texana AAW66445.1     15
 α-amylase 38/58 (Amy;Amy35;Amy58;AmyTBU118)   Drosophila ananassae AAC79123.1
AAC47353.1
AAC79122.1
BAA22481.1
O15947
O18345
Q23835
  15
 α-amylase 4N (Amy4N)   Drosophila ananassae AAC48343.1
AAC47352.1
Q23834   15
 α-amylase C1 3.2.1.1 Drosophila ananassae AAC35243.1 O77407   15
 Amy C6 (Amyrel)   Drosophila ananassae AAC39090.3 O18344   15
 Amyrel (fragment)   Drosophila angularis AAW66435.1     15
 Amyrel   Drosophila aracataca AAW64455.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila aracataca 15040-1171.00 AHL43632.1     15
 alpha amylase, partial (fragment)   Drosophila aracataca 15040-1171.00 AHL43644.1     15
 Amyrel (fragment)   Drosophila aracea AAW66436.1     15
 Amyrel   Drosophila ararama AAW64451.1     15
 Amyrel   Drosophila arawakana AAO84660.1 Q86N69   15
 Amy (fragment)   Drosophila arawakana AAQ13446.1 Q5NKY1   15
 amylase-related protein, partial (AmyreL) (fragment)   Drosophila arizonae AJP07832.1     15
 Amyrel   Drosophila asahinai AAL99575.1 Q8T7Y0   15
 α-amylase (Amy) (fragment)   Drosophila athabasca AAN16149.1     15
 α-amylase (Amy) (fragment)   Drosophila athabasca AAN16150.1 Q71V28   15
 amylase-related protein (Amyrel) (fragment)   Drosophila athabasca AAN16196.1     15
 Amyrel   Drosophila atripex AAC39104.3 O77011   15
 putative amylase   Drosophila auraria AAC39113.2 O77020   15
 Amy / Amy3 (fragment)   Drosophila auraria BAA22482.1 O15948   15
 Amy / Amy6 (fragment)   Drosophila auraria BAA22483.1 O15949   15
 α-amylase (fragment)   Drosophila auraria 14028-0471.0 (BOWLING GREEN STOCK CENTER) AAG42549.1     15
 amylase (fragment)   Drosophila auraria SHANGHAI-1 BAC53957.1 Q8IAI3   15
 α-amylase (fragment)   Drosophila azteca AAN16158.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila azteca 14012-0171-4 AAN16170.1     15
 AmyreL (fragment)   Drosophila baimaii AEM77111.1     15
 amylase (fragment)   Drosophila baimaii 14028.0481.0 BAC53965.1 Q8IAF2   15
 putative amylase   Drosophila bakoue AAC39112.2 O77019   15
 Amyrel   Drosophila barbarae AAL99577.1 Q8T7X8   15
 amylase (fragment)   Drosophila barbarae BAC53966.1 Q8IAF1   15
 amylase (fragment)   Drosophila barbarae BAC53967.1 Q8IAF0   15
 Amyrel   Drosophila biarmipes AAO14606.1 Q8I9R3   15
 amylase   Drosophila biarmipes IND_DBR_U4 ANZ79221.1     15
 α-amylase (fragment)   Drosophila biauraria AAM69518.1 Q8MX70   15
 Amyrel   Drosophila biauraria AAF25714.2 Q86S14   15
 Amy2 (fragment)   Drosophila biauraria 14028-0501.0 (BOWLING GREEN STOCK CENTER) AAG42550.1     15
 Amyrel   Drosophila bicornuta AAF25715.1 Q86S13   15
 Amy2 (fragment)   Drosophila bicornuta 14028-0511.1 (BOWLING GREEN STOCK CENTER) AAG42559.1     15
 Amy1 (fragment)   Drosophila bicornuta 14028-0511.1 (BOWLING GREEN STOCK CENTER) AAG42558.1     15
 Amyrel   Drosophila bifasciata AAL99395.1
AAN16155.1
Q8T7W5   15
 α-amylase (Amy) (fragment)   Drosophila bifasciata AAN16152.1     15
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