Glycoside Hydrolase Family 13 / Subf 15

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (919); Uniprot accession (380); PDB accession (4); 3D entries (1); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 Amyrel   Drosophila lucipennis AAL99398.1 Q8T7W2   15
 amylase-related protein (fragment)   Drosophila luguensis AEL29513.1     15
 Amyrel   Drosophila lummei AAW64449.1     15
 Amyrel   Drosophila lutescens AAO84667.1 Q86N62   15
 Amy (fragment)   Drosophila lutescens AEM77096.1     15
 Amy1 (fragment)   Drosophila lutescens PGE AAG42566.1     15
 Amy2 (fragment)   Drosophila lutescens PGE AAG42565.1     15
 Amy3 (fragment)   Drosophila lutescens PGE AAG42564.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila machalilla E035 AHL43636.1     15
 alpha amylase, partial (fragment)   Drosophila machalilla E035 AHL43650.1     15
 α-amylase (Amy) (fragment)   Drosophila madeirensis AAN16144.1     15
 AMYREL (fragment)   Drosophila madeirensis AAN16204.1     15
 Amy (fragment)   Drosophila madikerii AEM77105.1     15
 AmyreL (fragment)   Drosophila madikerii AEM77118.1     15
 Amyrel   Drosophila malagassya AAL99581.1 Q8T7X5   15
 Amy (fragment)   Drosophila malerkotliana AEM77109.1     15
 Amyrel   Drosophila malerkotliana AAW64456.1     15
 Amyrel   Drosophila malerkotliana pallens AAW64457.1     15
 α-amylase-like   Drosophila mauritiana AAC39107.2
AEK11596.1
AEK11597.1
AEK11598.1
AEK11600.1
AEK11601.1
AEK11602.1
AEK11603.1
AEK11604.1
AEK11605.1
AEK11606.1
AEK11609.1
AEK11610.1
AEK11611.1
AEK11612.1
AEK11613.1
AEK11614.1
AEK11615.1
AEK11616.1
AEK11618.1
AEK11621.1
AEK11622.1
AEK11623.1
AEK11625.1
AEK11626.1
AEK11627.1
AEK11628.1
AEK11630.1
AEK11631.1
AEK11632.1
AEK11633.1
AEK11634.1
AEK11636.1
AEK11637.1
AEK11638.1
AEK11639.1
AEK11640.1
AEK11641.1
AEK11642.1
AEK11643.1
AEK11644.1
AEK11645.1
AEK11646.1
AEK11647.1
AEK11648.1
AEK11649.1
O77014   15
 α-amylase A 3.2.1.1 Drosophila mauritiana BAA04583.1
BAA04584.1
P54215   15
 Amy (fragment)   Drosophila mayri AEM77104.1     15
 AmyreL (fragment)   Drosophila mayri AEM77119.1     15
 amylase (fragment)   Drosophila mayri 14028-0591.0 BAB39185.1 Q8IAG9   15
 Amyrel   Drosophila mediopictoides AAW64458.1     15
 Amyrel   Drosophila melanica AAW64459.1     15
 Amyrel (CG8221)   Drosophila melanogaster AAK93479.1
AAD08845.1
AAD09147.1
AAF57971.1
NP_477262.1
O18408   15
 α-amylase (AmyD;AmyP;Amy-p;DMA;CG18730) 3.2.1.1 Drosophila melanogaster AAA92226.1
AAA92227.1
AAA92228.1
AAA92229.1
AAA92230.1
AAA92231.1
AAA92232.1
AAA92233.1
AAA92234.1
AAA92235.1
AAA92236.1
AAA92237.1
AAA92238.1
AAA92239.1
AAA92240.1
AAA92241.1
AAA92242.1
AAA92243.1
AAF57894.1
AAQ94115.1
AAQ94116.1
AAQ94117.1
BAB32503.1
BAB32504.1
BAB32505.1
BAB32506.1
BAB32507.1
BAB32508.1
BAB32509.1
BAB32510.1
BAB32511.1
BAB32512.1
BAB32513.1
BAB32514.1
BAB32515.1
BAB32516.1
BAB32517.1
BAB32518.1
BAB32519.1
BAB32520.1
BAB32521.1
BAB32522.1
BAB32523.1
BAB32524.1
BAB32525.1
BAB32526.1
BAB32527.1
BAB32528.1
BAB32529.1
BAB32530.1
BAB32531.1
BAB32532.1
BAB32533.1
BAB32534.1
BAB32535.1
BAB32537.1
BAB32538.1
BAB32539.1
BAB32540.1
BAB32541.1
BAB32542.1
BAB32543.1
BAB32544.1
BAB32545.1
CAA28238.1
CAA59126.1
NP_523768.1
NP_536346.1
P08144
Q9BPT3
  15
 CG18640   Drosophila melanogaster AAF57896.1
AAK92849.1
AAQ82588.1
AAQ82589.1
AAQ82590.1
AAX33373.1
AHN56314.1
P08144
P81641
  15
 α-amylase (Amy-d)   Drosophila melanogaster JP-169 BAB72141.1 P08144
P81641
Q5BIJ9
  15
 α-amylase (Amy-p)   Drosophila melanogaster JP-169 BAB72090.1 P08144   15
 α-amylase (Amy-d)   Drosophila melanogaster JP-186 BAB72142.1 P08144
P81641
Q5BIJ9
  15
 α-amylase (Amy-p)   Drosophila melanogaster JP-186 BAB72091.1 P08144   15
 α-amylase (Amy-d)   Drosophila melanogaster JP-190 BAB72143.1 P08144
P81641
Q5BIJ9
  15
 α-amylase (Amy-p)   Drosophila melanogaster JP-190 BAB72092.1 P08144   15
 Amy (fragment)   Drosophila mercatorum AAQ13454.1 Q5NKX3   15
 Amy (fragment)   Drosophila mercatorum AAQ13455.1 Q5NKX2   15
 Amy (fragment)   Drosophila mercatorum HOLLAND AAQ13453.1 Q5NKX4   15
 Amyrel   Drosophila merina AAW64460.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila mettleri 15081-1502.00 AHL43637.1     15
 alpha amylase, partial (fragment)   Drosophila mettleri 15081-1502.00 AHL43651.1     15
 Amyrel   Drosophila metzii AAW78377.1     15
 α-amylase (Amy) (fragment)   Drosophila microlabis AAN16145.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila microlabis AAN16169.1     15
 putative amylase (fragment)   Drosophila microlabis AAC47362.1 Q24102   15
 Amyrel   Drosophila mimetica AAW64461.1     15
 Amyrel (fragment)   Drosophila mimica AAW66442.1     15
 putative amylase (fragment)   Drosophila miranda BAA22494.1
BAA22495.1
O15960
O15961
  15
 amylase distal, partial (Amy-D) (fragment)   Drosophila mitchelli AFM76794.1     15
 Amy (fragment)   Drosophila mojavensis AAQ13451.1 Q5NKX6   15
 Amyrel   Drosophila monieri AAL99576.1 Q8T7X9   15
 Amyrel   Drosophila nagarholensis AAL99578.1 Q8T7X7   15
 amylase (fragment)   Drosophila nagarholensis INDIA BAB39188.1 Q8IAG6   15
 amylase (fragment)   Drosophila nagarholensis INDIA BAB39187.1 Q8IAG7   15
 α-amylase (Amy 1)   Drosophila nagarholensis PGE BAC06331.1 Q8MY55   15
 α-amylase (Amy 2)   Drosophila nagarholensis PGE BAC06332.1 Q8MY54   15
 α-amylase (Amy 3)   Drosophila nagarholensis PGE BAC06333.1 Q8MY53   15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila nannoptera 15090-1692.10 AHL43638.1     15
 alpha amylase, partial (fragment)   Drosophila nannoptera 15090-1692.10 AHL43652.1     15
 α-amylase (Amy) (fragment)   Drosophila narragansett AAN16200.1     15
 Amyrel   Drosophila nasuta AAW64462.1     15
 amyrel protein, partial (fragment)   Drosophila nasuta ADM3 BAR88683.1
BAR88684.1
BAR88685.1
BAR88686.1
BAR88687.1
BAR88688.1
BAR88689.1
BAR88690.1
BAR88691.1
BAR88692.1
BAR88693.1
BAR88694.1
BAR88695.1
BAR88696.1
BAR88697.1
BAR88698.1
    15
 amylase   Drosophila nasuta IND_DN_U11 ANZ79224.1     15
 Amyrel   Drosophila nebulosa AAW64463.1     15
 Amyrel   Drosophila neocordata AAW66386.1     15
 Amyrel   Drosophila neomorpha AAW66387.1     15
 Amy (fragment)   Drosophila nigrodumosa AAQ13452.1 Q5NKX5   15
 Amyrel   Drosophila nigrodumosa AAW66388.1     15
 Amyrel   Drosophila nigromaculata AAW66389.1     15
 Amyrel (fragment)   Drosophila nigromelanica AEQ63844.1     15
 Amyrel   Drosophila nikananu AAL99396.1 Q8T7W4   15
 α-amylase (fragment)   Drosophila nikananu AAM69529.1 Q8MX59   15
 α-amylase (fragment)   Drosophila nikananu AAM69530.1 Q8MX58   15
 α-amylase (fragment)   Drosophila nikananu AAM69531.1 Q8MX57   15
 amylase (fragment)   Drosophila nikananu INDIA14028.0601.0 BAB39189.1 Q8IAG5   15
 Amyrel   Drosophila novamexicana AAW66390.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila obscura AAN16194.1     15
 α-amylase (Amy) (fragment)   Drosophila obscura SPIER AAN16146.1     15
 Amyrel   Drosophila ochrogaster AAW66391.1     15
 Amy (fragment)   Drosophila ogumai AEM77103.1     15
 AmyreL (fragment)   Drosophila ogumai AEM77120.1     15
 Amy (fragment)   Drosophila ohnishii AEM77102.1     15
 AmyreL (fragment)   Drosophila ohnishii AEM77121.1     15
 α-amylase-like   Drosophila orena AAC39108.2
AAC39108.1
O77015   15
 Amy   Drosophila orena BAA04666.1
BAA04667.1
Q24610
Q24611
  15
 amylase (fragment)   Drosophila orosa INDIA14028.0611.0 BAB39190.1 Q8IAG4   15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila pachea 15090-1698.02 AHL43639.1     15
 alpha amylase, partial (fragment)   Drosophila pachea 15090-1698.02 AHL43653.1     15
 Amyrel   Drosophila pallidifrons AAW66392.1     15
 Amyrel   Drosophila pallidipennis AAW66393.1     15
 Amyrel   Drosophila pallidosa AAF25713.1 Q9NJN9   15
 Amyrel (fragment)   Drosophila palustris AAW66443.1     15
 Amy (fragment)   Drosophila parabipectinata AEM77108.1     15
 Amyrel   Drosophila parabipectinata AAW66395.1     15
 AmyreL (fragment)   Drosophila parvula AEM77122.1     15
 amylase (fragment)   Drosophila parvula CNX312 BAB39191.1 Q8IAG3   15
 Amyrel   Drosophila pavani AAW66396.1     15
 α-amylase (Amy) (fragment)   Drosophila persimilis AAN16151.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila persimilis AAN16165.1     15
 putative amylase (fragment)   Drosophila persimilis BAA22496.1
BAA22497.1
O15962
O15963
  15
 Amyrel   Drosophila phaeopleura AAW66397.1     15
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