Glycoside Hydrolase Family 13 / Subf 15

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (919); Uniprot accession (380); PDB accession (4); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase I (AmyI) 3.2.1.1 Aedes aegypti AAA29343.1
AAA29344.1
AAA29345.1
AAB60935.1
O02413
P53354
  15
 α-amylase II (AmyII) 3.2.1.1 Aedes aegypti AAB60934.1 O02652   15
 α-amylase 3.2.1.1 Aedes atropalpus AAA03322.1 Q16924   15
 α-amylase 3.2.1.1 Anopheles merus AAA03323.1 Q17059   15
 α-amylase (Amylag1) 3.2.1.1 Anthonomus grandis AAN77138.1
AOG18226.1
Q8I9K6   15
 α-amylase (Amylag2) 3.2.1.1 Anthonomus grandis AAN77139.1 Q8I9K5   15
 α-amylase (Amy) 3.2.1.1 Asterias rubens AAO13755.1 Q8IA45   15
 α-amylase (bgtg-1) 3.2.1.1 Blattella germanica AAY23288.1 Q2KJQ1   15
 α-amylase (Ccam) 3.2.1.1 Callosobruchus chinensis BAB72257.1
BAD83655.1
    15
 α-amylase 3.2.1.1 Culex tarsalis AAA03350.1 Q23767   15
 α-amylase 3.2.1.1 Diabrotica virgifera virgifera AAF20998.1 Q9U406   15
 α-amylase C1 3.2.1.1 Drosophila ananassae AAC35243.1 O77407   15
 α-amylase (Amy4) 3.2.1.1 Drosophila bocki A65 BAA95436.1 Q9NKZ0   15
 α-amylase (Amy3) 3.2.1.1 Drosophila bocki A65 BAA95435.1 Q9NKZ1   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki A65 BAA95434.1 Q9NKZ2   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki A65 BAA95433.1 Q9NKZ3   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki A94 BAB91544.1 Q9NKZ2   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki A94 BAB91547.1 Q8N0P7   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki AO-1 BAB91546.1 Q8N0P8   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki AO-1 BAB91549.1 Q8N0P5   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki IRO2-37 BAB91545.1 Q8N0P9   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki IRO2-37 BAB91548.1 Q8N0P6   15
 α-amylase (proximal) (Amy) 3.2.1.1 Drosophila erecta BAA04582.1 Q23932   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai BAB91509.1 Q8MM52   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai CJB202 BAB91542.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai CJB216 BAB91520.1 Q8MM99   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai CJB216 BAB91543.1 Q8N0Q0   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai HNL122 BAB91514.1 Q8N0Q6   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai HNL122 BAB91536.1 Q8MM80   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai HNL124 BAB91515.1 Q8N0Q5   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai HNL124 BAB91537.1 Q8MM80   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai HNL126 BAB91516.1 Q8MM52   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai HNL126 BAB91538.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai HNL202 BAB91517.1 Q8N0Q4   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai HNL202 BAB91539.1 Q8N0Q2   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai HYD101 BAB91518.1 Q8MLY6   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai HYD101 BAB91540.1 Q8N0Q1   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai HYD102 BAB91519.1 Q8MM99   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai HYD102 BAB91541.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai MDL172 BAB91508.1 Q8MM99   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai MDL172 BAB91530.1 Q8MM80   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai MDL173 BAB91531.1 Q8N0Q3   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai MDL178 BAB91510.1 Q8MM52   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai MDL178 BAB91532.1 Q8MLX9   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai MIYAKO-2 BAB91506.1 Q8MM52   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai MIYAKO-2 BAB91528.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai MIYAKO-4 BAB91507.1 Q8MM52   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai MIYAKO-4 BAB91529.1 Q9NKZ4   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai NAGO-1 BAB91502.1 Q8N0R0   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAGO-1 BAB91524.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai NAGO-2 BAB91503.1 Q8N0Q9   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAGO-2 BAB91525.1 Q8MM80   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai NAGO-3 BAB91504.1 Q8N0Q8   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAGO-3 BAB91526.1 Q8MM80   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai NAGO-4 BAB91505.1 Q8MM52   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAGO-4 BAB91527.1 Q9NKZ4   15
 α-amylase (Amy4) 3.2.1.1 Drosophila kikkawai NAHA-1 BAA95432.1 Q9N651   15
 α-amylase (Amy3) 3.2.1.1 Drosophila kikkawai NAHA-1 BAA95431.1 Q9N651   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAHA-1 BAA95430.1 Q9NKZ4   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai NAHA-1 BAA95429.1 Q9NKZ5   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai NAHA-2 BAB91501.1 Q8MM99   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAHA-2 BAB91521.1 Q9NKZ4   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAHA-3 BAB91522.1 Q8MM40   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai NAHA-4 BAB91523.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai RGN31 BAB91513.1 Q8N0Q7   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai RGN31 BAB91535.1 Q8MM40   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai SWB174 BAB91511.1 Q8MLY6   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai SWB174 BAB91533.1 Q8MLX9   15
 α-amylase (Amy1) 3.2.1.1 Drosophila kikkawai SWB184 BAB91512.1 Q8MLY6   15
 α-amylase (Amy2) 3.2.1.1 Drosophila kikkawai SWB184 BAB91534.1 Q8MM40   15
 α-amylase (Amy4) 3.2.1.1 Drosophila leontia RGN210-8 BAA95440.1 Q9NKY6   15
 α-amylase (Amy3) 3.2.1.1 Drosophila leontia RGN210-8 BAA95439.1 Q9NKY7   15
 α-amylase (Amy2) 3.2.1.1 Drosophila leontia RGN210-8 BAA95438.1 Q9NKY8   15
 α-amylase (Amy1) 3.2.1.1 Drosophila leontia RGN210-8 BAA95437.1 Q9NKY9   15
 α-amylase (Amy3) 3.2.1.1 Drosophila lini 14028-0581.0 BAA95443.1
AAM69526.1
AAM69527.1
AAM69528.1
Q8MX60
Q8MX61
Q8MX62
Q9NKY5
  15
 α-amylase (Amy2) 3.2.1.1 Drosophila lini 14028-0581.0 BAA95442.1 Q9N6Q7   15
 α-amylase (Amy1) 3.2.1.1 Drosophila lini 14028-0581.0 BAA95441.1 Q9N6Q7   15
 α-amylase A 3.2.1.1 Drosophila mauritiana BAA04583.1
BAA04584.1
P54215   15
 α-amylase (AmyD;AmyP;Amy-p;DMA;CG18730) 3.2.1.1 Drosophila melanogaster AAA92226.1
AAA92227.1
AAA92228.1
AAA92229.1
AAA92230.1
AAA92231.1
AAA92232.1
AAA92233.1
AAA92234.1
AAA92235.1
AAA92236.1
AAA92237.1
AAA92238.1
AAA92239.1
AAA92240.1
AAA92241.1
AAA92242.1
AAA92243.1
AAF57894.1
AAQ94115.1
AAQ94116.1
AAQ94117.1
BAB32503.1
BAB32504.1
BAB32505.1
BAB32506.1
BAB32507.1
BAB32508.1
BAB32509.1
BAB32510.1
BAB32511.1
BAB32512.1
BAB32513.1
BAB32514.1
BAB32515.1
BAB32516.1
BAB32517.1
BAB32518.1
BAB32519.1
BAB32520.1
BAB32521.1
BAB32522.1
BAB32523.1
BAB32524.1
BAB32525.1
BAB32526.1
BAB32527.1
BAB32528.1
BAB32529.1
BAB32530.1
BAB32531.1
BAB32532.1
BAB32533.1
BAB32534.1
BAB32535.1
BAB32537.1
BAB32538.1
BAB32539.1
BAB32540.1
BAB32541.1
BAB32542.1
BAB32543.1
BAB32544.1
BAB32545.1
CAA28238.1
CAA59126.1
NP_523768.1
NP_536346.1
P08144
Q9BPT3
  15
 α-amylase 3.2.1.1 Drosophila pseudoobscura AAC46839.1
AAA73568.1
AAA73569.1
AAA73570.1
AAA73571.1
AAC46840.1
AAC46841.1
AAC46842.1
AEM77093.1
CAA53819.1
CAA53820.1
CAA53821.1
O46116
Q24609
Q24613
Q27609
Q27610
Q27611
Q27612
Q27863
Q27891
  15
 α-amylase (Amy) 3.2.1.1 Drosophila sechellia BAA04585.1 Q24642   15
 α-amylase 3.2.1.1 Drosophila virilis AAC46463.1 Q24737   15
 α-amylase A 3.2.1.1 Drosophila yakuba AAG60011.1
AAG60012.1
AAG60013.1
AAG60014.1
BAA04590.1
BAA04591.1
P51548
Q9BN01
  15
 α-amylase 3.2.1.1 Phaedon cochleariae CAA76926.1 O97396   15
 α-amylase 3.2.1.1 Tenebrio molitor   P56634 1CLV[A]
1JAE[A]
1TMQ[A]
1VIW[A]
15
 α-amylase I 3.2.1.1 Tribolium castaneum AAA03708.1
AGW27504.1
AGW27506.1
Q26854   15
 α-amylase II 3.2.1.1 Tribolium castaneum AAA03709.1 Q26855   15
 α-amylase 3.2.1.1 Zabrotes subfasciatus AAF73435.1 Q9N2P9   15
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