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Glycoside Hydrolase Family 12

Activities in FamilyXyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Mechanism Retaining e
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (2968); Uniprot accession (90); PDB accession (61); 3D entries (23); cryst (1)
Summary
Download GH12 (4778) Taxonomic display Structure (23 - 1 cryst) Characterized (89)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 26 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 2291   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)      
 9699   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)      
 103782   Aspergillus fumigatus A1163 (Aspfu_A1163_1)      
 103530   Aspergillus fumigatus A1163 (Aspfu_A1163_1)      
 99661   Aspergillus fumigatus A1163 (Aspfu_A1163_1)      
 108068   Aspergillus fumigatus A1163 (Aspfu_A1163_1)      
 endoglucanase (AfCel12A;Afu7g06150;AFUA_7G06150) (Cel12A) 3.2.1.4
3.2.1.151		 Aspergillus fumigatus Af293 EAL86857.1 Q4WGT4  
 441   Aspergillus fumigatus Af293 (Aspfu1)      
 9018   Aspergillus fumigatus Af293 (Aspfu1)      
 3622   Aspergillus fumigatus Af293 (Aspfu1)      
 3383   Aspergillus fumigatus Af293 (Aspfu1)      
 120778   Aspergillus glaucus v1 (Aspgl1)      
 endoglucanase (Cel12B) 3.2.1.4 Aspergillus kawachii IFO 4308 AAM77715.1
AAR63634.1
AAR67687.1
ABJ29218.1
ACP76237.1		 Q8NJY2  
 endo-β-1,4-glucanase (CekA) 3.2.1.4 Aspergillus kawachii IFO 4308 AAR63633.1
AAR67686.1
ABJ29217.1
ACP76236.1
BAA02297.1		 Q12679  
 16620   Aspergillus kawachii IFO 4308 (Aspka1_1)      
 18303   Aspergillus kawachii IFO 4308 (Aspka1_1)      
 20540   Aspergillus kawachii IFO 4308 (Aspka1_1)      
 20528   Aspergillus kawachii IFO 4308 (Aspka1_1)      
 184666   Aspergillus leporis CBS 151.66 v1.0 (Asplep1)      
 175060   Aspergillus leporis CBS 151.66 v1.0 (Asplep1)      
 157702   Aspergillus leporis CBS 151.66 v1.0 (Asplep1)      
 171150   Aspergillus leporis CBS 151.66 v1.0 (Asplep1)      
 196306   Aspergillus acidus v1 (Aspfo1)      
 202443   Aspergillus acidus v1 (Aspfo1)      
 50775   Aspergillus acidus v1 (Aspfo1)      
 48451   Aspergillus acidus v1 (Aspfo1)      
 AKAW2_20502A   Aspergillus luchuensis IFO 4308 BCR95562.1    
 AKAW2_50925A   Aspergillus luchuensis IFO 4308 BCS00584.1    
 AKAW2_50911A   Aspergillus luchuensis IFO 4308 BCS00570.1    
 AKAW2_40952A   Aspergillus luchuensis IFO 4308 BCR99269.1    
 ALUC_40915A   Aspergillus luchuensis RIB2601 BCS11575.1    
 ALUC_20471A   Aspergillus luchuensis RIB2601 BCS08101.1    
 ALUC_50397A   Aspergillus luchuensis RIB2601 BCS12351.1    
 ALUC_50385A   Aspergillus luchuensis RIB2601 BCS12339.1    
 250859   Aspergillus minisclerotigenes v1.0 (Aspmin1)      
 207830   Aspergillus minisclerotigenes v1.0 (Aspmin1)      
 205865   Aspergillus minisclerotigenes v1.0 (Aspmin1)      
 226387   Aspergillus minisclerotigenes v1.0 (Aspmin1)      
 6306   Aspergillus nidulans FGSC A4 (Aspnid1)      
 endo-β-1,4-glucanase (xyloglucan-specific) (AN0452.2) 3.2.1.151 Aspergillus nidulans FGSC A4 EAA66551.1
ABF50842.1		 Q5BG78  
 endoglucanase (EgL)   Aspergillus niger QEQ56120.1    
 267810   Aspergillus phoenicis (Corda) Thom ATCC 13157 v1.0 (Aspph1)      
 238980   Aspergillus phoenicis (Corda) Thom ATCC 13157 v1.0 (Aspph1)      
 101463   Aspergillus phoenicis (Corda) Thom ATCC 13157 v1.0 (Aspph1)      
 58967   Aspergillus phoenicis (Corda) Thom ATCC 13157 v1.0 (Aspph1)      
 1161570   Aspergillus niger ATCC 1015 v4 (Aspni7)      
 1142168   Aspergillus niger ATCC 1015 v4 (Aspni7)      
 1109949   Aspergillus niger ATCC 1015 v4 (Aspni7)      
 1186628   Aspergillus niger ATCC 1015 v4 (Aspni7)      
 endoglucanase (EglA)   Aspergillus niger ATCC 10574 ADC84000.1    
 endo-β-1,4-glucanase (EglA; AnEglA) 3.2.1.4 Aspergillus niger CBS 120.49 / N400 AAE60101.1
AAE84291.1
CAA03652.1
CAA03657.1
CAA11964.1
CAG17891.1		 O74705 1KS4[A]
1KS5[A]
 An03g05530   Aspergillus niger CBS 513.88 CAG17892.1
CAK38314.1		    
 An01g03340   Aspergillus niger CBS 513.88 CAK36874.1    
 An03g05380   Aspergillus niger CBS 513.88 CAK38300.1    
 endo-β-1,4-glucanase (EglA;An14g02760) 3.2.1.4 Aspergillus niger CBS 513.88 CAK46524.1 A2R322  
 166061   Aspergillus niger CBS 513.88 (Aspni_DSM_1)      
 158544   Aspergillus niger CBS 513.88 (Aspni_DSM_1)      
 158530   Aspergillus niger CBS 513.88 (Aspni_DSM_1)      
 155384   Aspergillus niger CBS 513.88 (Aspni_DSM_1)      
 endoglucanase 3.2.1.4 Aspergillus niger HO AIX97359.1 O74705  
 xyloglucan-specific endo-β-1,4-glucanase (Xeg12A) 3.2.1.151 Aspergillus niger N402 ABF46829.1 A1XP58  
 819   Aspergillus niger NRRL3 (Aspni_NRRL3_1)      
 8392   Aspergillus niger NRRL3 (Aspni_NRRL3_1)      
 8380   Aspergillus niger NRRL3 (Aspni_NRRL3_1)      
 1918   Aspergillus niger NRRL3 (Aspni_NRRL3_1)      
 368475   Aspergillus niger van Tieghem ATCC 13496 v1.0 (Aspni_bvT_1)      
 5215   Aspergillus niger van Tieghem ATCC 13496 v1.0 (Aspni_bvT_1)      
 293946   Aspergillus niger van Tieghem ATCC 13496 v1.0 (Aspni_bvT_1)      
 334034   Aspergillus niger van Tieghem ATCC 13496 v1.0 (Aspni_bvT_1)      
 endoglucanase A (EglA) (partial) 3.2.1.4 Aspergillus niger VTCC F-021 / VTCC-F021 ADD12042.1 D3YC02  
 xyloglucan-specific endo-β-1,4-glucanase (XegA) 3.2.1.151 Aspergillus niveus PR-2 AEV23011.1 H6TQN1 4NPR[A,B]
 138665   Aspergillus nomius v1.0 (Aspnom1)      
 157932   Aspergillus nomius v1.0 (Aspnom1)      
 160581   Aspergillus nomius v1.0 (Aspnom1)      
 145810   Aspergillus nomius v1.0 (Aspnom1)      
 28687   Aspergillus nomius v1.0 (Aspnom1)      
 3987   Aspergillus nomius NRRL 13137 (Aspnom13137_1)      
 10146   Aspergillus nomius NRRL 13137 (Aspnom13137_1)      
 61   Aspergillus nomius NRRL 13137 (Aspnom13137_1)      
 11170   Aspergillus nomius NRRL 13137 (Aspnom13137_1)      
 2672   Aspergillus nomius NRRL 13137 (Aspnom13137_1)      
 239361   Aspergillus novofumigatus IBT 16806 v1 (Aspnov1)      
 375724   Aspergillus novofumigatus IBT 16806 v1 (Aspnov1)      
 369455   Aspergillus novofumigatus IBT 16806 v1 (Aspnov1)      
 207435   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)      
 170131   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)      
 173531   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)      
 196752   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)      
 94911   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)      
 430638   Aspergillus ochraceoroseus IBT 24754 v1.0 (Aspoch1)      
 endo-β-1,4-glucanase (CelA) 3.2.1.4 Aspergillus oryzae KBN616 BAA22588.1
AAR63635.1
AAR67688.1
ABJ29219.1
ACP76238.1		 O13454  
 xyloglucan-specific endo-β-1,4-glucanase (Xeg12A; AO090003000905) (Xeg12A) 3.2.1.151 Aspergillus oryzae RIB40 BAE58022.1 Q2UK93  
 endo-β-1,4-glucanase (CelA;AO090026000102) 3.2.1.4 Aspergillus oryzae RIB40 BAE59597.1 Q2UFR8  
 AO090701000185   Aspergillus oryzae RIB40 BAE61926.1    
 AO090038000175   Aspergillus oryzae RIB40 BAE64005.1    
 5606   Aspergillus oryzae RIB40 (Aspor1)      
 9687   Aspergillus oryzae RIB40 (Aspor1)      
 3485   Aspergillus oryzae RIB40 (Aspor1)      
 7835   Aspergillus oryzae RIB40 (Aspor1)      
 210643   Aspergillus parasiticus CBS 117618 v1.0 (Asppar1)      
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