Glycoside Hydrolase Family 12

Activities in Familyendoglucanase (EC 3.2.1.4); xyloglucan hydrolase (EC 3.2.1.151); β-1,3-1,4-glucanase (EC 3.2.1.73); xyloglucan endotransglycosylase (EC 2.4.1.207)
Mechanism Retaining
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (924); Uniprot accession (212); PDB accession (46); 3D entries (16); cryst (1)
All (732) Archaea (81) Bacteria (509) Eukaryota (141) unclassified (1) Structure (16 - 1 cryst) Characterized (68)
| 1 | 2 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 endoglucanase (EGL12-I) (Cel12I)   Phytophthora sojae ABB22031.1 Q30BZ0  
 endoglucanase (EGL12-H) (Cel12H)   Phytophthora sojae ABB22030.1 Q30BZ1  
 xyloglucan-specific endoglucanase (EGL12-G;XEG1;PsXEG1;Ps109681;PHYSODRAFT_559651) (Cel12G) 3.2.1.151 Phytophthora sojae ABB22029.1
EGZ16757.1
Q30BZ2  
 endoglucanase (EGL12-F) (Cel12F)   Phytophthora sojae ABB22028.1 Q30BZ3  
 endoglucanase (EGL12-E) (Cel12E)   Phytophthora sojae ABB22027.1 Q30BZ4  
 endoglucanase (EGL12-D) (Cel12D)   Phytophthora sojae ABB22026.1 Q30BZ5  
 endoglucanase (EGL12-C) (Cel12C)   Phytophthora sojae ABB22025.1 Q30BZ6  
 endoglucanase (EGL12-A) (Cel12A)   Phytophthora sojae ABB22024.1 Q30BZ7  
 Pa_4_6020   Podospora anserina S mat+ CAP66908.1
CDP28650.1
B2APW9  
 Pa_7_3370   Podospora anserina S mat+ CAP68354.1
CDP31825.1
B2AVD0  
 endoglucanase (Cel3A;CMCase3a;CMCase IIIa) 3.2.1.4 Polyporus arcularius 69B-8 BAD98315.1 Q50LE3  
 endo-β-1,4-glucanase (PpCel12A) (partial) (Cel12A) 3.2.1.4 Postia placenta Mad-698-R ADH51731.1 D7REW4  
 xyloglucanase B (RmXEG12B) (Xeg12B) 3.2.1.151 Rhizomucor miehei CAU432 AGC24033.1    
 xyloglucanase A (RmXEG12A) (Xeg12A) 3.2.1.151 Rhizomucor miehei CAU432 AGC24032.1    
 endo-β-1,4-xyloglucan (Xyn1)   Rhizopus stolonifer AHZ13945.1    
 endoglucanase V (EgV)   Rhizopus stolonifer var. reflexus TP-02 AJS10817.1    
 sscle_03g026590   Sclerotinia sclerotiorum 1980 UF-70 APA07889.1    
 sscle_15g104530   Sclerotinia sclerotiorum 1980 UF-70 APA15683.1    
 sscle_09g069440   Sclerotinia sclerotiorum 1980 UF-70 APA12174.1    
 sscle_15g106400   Sclerotinia sclerotiorum 1980 UF-70 APA15870.1    
 sscle_04g034060   Sclerotinia sclerotiorum 1980 UF-70 APA08636.1    
 PIIN_09685   Serendipita indica DSM 11827 CCA75695.1    
 PIIN_06838 (fragment)   Serendipita indica DSM 11827 CCA72902.1    
 β-glucanase (lichenase-like) (Cel12A)   Stachybotrys chartarum CECT 20565 / Stachybotrys atra BP-A CAL48345.1 Q08HM8  
 endocellulase (Eg12)   Thanatephorus cucumeris AG-1-IA ACT78705.1
ACT78560.1
C7AGU1  
 MYCTH_109444   Thermothelomyces thermophila ATCC 42464 AEO60532.1    
 endo-β-1,4-glucanase (C173)   Thermothelomyces thermophila CBS 117.65 AAN94974.1    
 THITE_2043508   Thielavia terrestris NRRL 8126 AEO67160.1    
 THITE_2117762   Thielavia terrestris NRRL 8126 AEO68296.1    
 THITE_121780   Thielavia terrestris NRRL 8126 AEO69079.1    
 endo-β-1,4-glucanase 3 / III (Egl3;EG3;EGIII;ThEG3;ThEGIII) (Cel12A)   Trichoderma harzianum IOC-3844 AFK32784.1   4H7M[A,B]
 CMCase   Trichoderma harzianum WF5 AIK67328.1    
 endoglucanase (Cel12A)   Trichoderma koningii ATCC 2613 AAM77712.1 Q8NJY5  
 endogluanase III   Trichoderma pseudokoningii ABM90985.1 A2TDD5  
 endo-β-1,4-glucanase III (Egl3;EGIII;EG III;EG3;TrCel12A) (Cel12A) 3.2.1.151
3.2.1.4
Trichoderma reesei QM9414 AAE59774.1
AAE59775.1
AAN19479.1
AAN19480.1
AAO95538.1
AAO95539.1
AAQ24888.1
AAQ42100.1
AAQ42101.1
AAR60524.1
AAR63629.1
AAR63630.1
AAR67682.1
AAR67683.1
ABE22099.1
ABJ29213.1
ABJ29214.1
ABV71388.1
ACP76232.1
ACP76233.1
BAA20140.1
O00095 1H8V[A,B,C,D,E,F]
1OA2[A,B,C,D,E,F]
1OLQ[A,B]
 endoglucanase I   Trichoderma viride AAS18313.1 Q6QTF2  
 endoglucanase (Cel12A)   Trichoderma viride ATCC 26802 AAM77713.1 Q8NJY4  
 unknown (possible fungal contaminant)   Zea mays ACG26880.1 B6SPU7  
 ZT1A5_G9613   Zymoseptoria tritici ST99CH_1A5 SMY28168.1    
 ZT3D7_G5119   Zymoseptoria tritici ST99CH_3D7 SMQ49967.1    
 ZT3D7_G9671 (fragment)   Zymoseptoria tritici ST99CH_3D7 SMQ54516.1    
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