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Glycoside Hydrolase Family 12

Activities in FamilyXyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Mechanism Retaining e
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (2916); Uniprot accession (90); PDB accession (61); 3D entries (23); cryst (1)
Summary
Download GH12 (4726) Taxonomic display Structure (23 - 1 cryst) Characterized (88)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 25 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 10127   Ascocoryne sarcoides NRRL50072 (Ascsa1)      
 xyloglucanase 2 (XEG2) (fragment)   Aspergillus aculeatus AAO20340.1    
 endo-β-1,4-glucanase I (EndI)   Aspergillus aculeatus AFD53250.1    
 endo-β-1,4-glucanase 1 (Cmc1;Cmc-1;FI CM-cellulase;FI-CMCase) 3.2.1.4 Aspergillus aculeatus F-50 BAA00435.1
AAR63632.1
AAR67685.1
ABJ29216.1
ACP76235.1
CAA36757.1		 P22669 5GM3[A,B]
5GM4[A,B,C,D,E,F,G]
5GM5[A,B,C,D,E,F,G]
 endo-β-1,4-glucanase (xyloglucan-specific) (XEG1) 3.2.1.151 Aspergillus aculeatus KSM 510 AAD02275.1 O94218 3VL8[A]
3VL9[A,B]
3VLB[B,D]
 174120   Aspergillus albertensis v1.0 (Aspalbe1)      
 2523   Aspergillus albertensis v1.0 (Aspalbe1)      
 194301   Aspergillus albertensis v1.0 (Aspalbe1)      
 174114   Aspergillus albertensis v1.0 (Aspalbe1)      
 183590   Aspergillus albertensis v1.0 (Aspalbe1)      
 153733   Aspergillus albertensis v1.0 (Aspalbe1)      
 194709   Aspergillus albertensis v1.0 (Aspalbe1)      
 322539   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 302106   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 323557   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 320838   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 306639   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 276060   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 299903   Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)      
 116912   Aspergillus arachidicola v1.0 (Aspara19utr)      
 162714   Aspergillus arachidicola v1.0 (Aspara19utr)      
 157393   Aspergillus arachidicola v1.0 (Aspara19utr)      
 155391   Aspergillus arachidicola v1.0 (Aspara19utr)      
 149714   Aspergillus arachidicola v1.0 (Aspara19utr)      
 137030   Aspergillus avenaceus IBT 18842 v1.0 (Aspave1)      
 127084   Aspergillus avenaceus IBT 18842 v1.0 (Aspave1)      
 163042   Aspergillus avenaceus IBT 18842 v1.0 (Aspave1)      
 endo-β-1,3-1,4-glucanase   Aspergillus awamori CAU33 AYH63706.1    
 260065   Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)      
 290356   Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)      
 278389   Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)      
 277412   Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)      
 989   Aspergillus bombycis NRRL 26010 (Aspbom1)      
 11052   Aspergillus bombycis NRRL 26010 (Aspbom1)      
 7045   Aspergillus bombycis NRRL 26010 (Aspbom1)      
 8323   Aspergillus bombycis NRRL 26010 (Aspbom1)      
 24729   Aspergillus brasiliensis v1 (Aspbr1)      
 134657   Aspergillus brasiliensis v1 (Aspbr1)      
 58604   Aspergillus brasiliensis v1 (Aspbr1)      
 120784   Aspergillus brasiliensis v1 (Aspbr1)      
 99612   Aspergillus brasiliensis v1 (Aspbr1)      
 153398   Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)      
 47356   Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)      
 89313   Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)      
 147594   Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)      
 129395   Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)      
 769038   Aspergillus calidoustus (Aspcal1)      
 769039   Aspergillus calidoustus (Aspcal1)      
 309215   Aspergillus campestris IBT 28561 v1 (Aspcam1)      
 290438   Aspergillus campestris IBT 28561 v1 (Aspcam1)      
 102071   Aspergillus candidus CBS 102.13 v1.0 (Aspcand1)      
 98740   Aspergillus candidus CBS 102.13 v1.0 (Aspcand1)      
 175662   Aspergillus carbonarius ITEM 5010 v3 (Aspca3)      
 514227   Aspergillus carbonarius ITEM 5010 v3 (Aspca3)      
 210467   Aspergillus carbonarius ITEM 5010 v3 (Aspca3)      
 xyloglucanase (GH12B; Xgh12B; AsCeGH12B) 3.2.1.151 Aspergillus cervinus VKPM F-612 AWN00461.1    
 endo-β-1,4-glucanase (GH12A; Bgh12A; AsCeGH12A) 3.2.1.4 Aspergillus cervinus VKPM F-612 AYM46706.1    
 ACHE_11624S   Aspergillus chevalieri M1 BCR84222.1    
 ACHE_30011S   Aspergillus chevalieri M1 BCR86024.1    
 ORF   Aspergillus chevalieri VKPM F-834 AYM46707.1    
 endo-xyloglucanase (XegA;AclaXegA;ACLA_029940) 3.2.1.151 Aspergillus clavatus NRRL 1 EAW08261.1 A1CRJ0  
 7968   Aspergillus clavatus NRRL 1 (Aspcl1)      
 3523   Aspergillus clavatus NRRL 1 (Aspcl1)      
 2954   Aspergillus clavatus NRRL 1 (Aspcl1)      
 133885   Aspergillus coremiiformis CBS 553.77 v1.0 (Aspcor1)      
 147258   Aspergillus coremiiformis CBS 553.77 v1.0 (Aspcor1)      
 134214   Aspergillus coremiiformis CBS 553.77 v1.0 (Aspcor1)      
 163711   Aspergillus coremiiformis CBS 553.77 v1.0 (Aspcor1)      
 5439   Aspergillus cristatus GZAAS20.1005 (Aspcri1)      
 1556   Aspergillus cristatus GZAAS20.1005 (Aspcri1)      
 xyloglucan-specific endo-β-1,4-glucanase (Xyg12A)   Aspergillus fischeri QBH72468.1    
 GH12 β-1, 4-endoglucanase   Aspergillus fischeri CGMCC 3.15369 APQ48493.1   6K98[A]
6K9D[A]
 G4B11_003651   Aspergillus flavus AF13 QMW40371.1    
 G4B11_008089   Aspergillus flavus AF13 QMW44669.1    
 G4B11_005779   Aspergillus flavus AF13 QMW42455.1    
 G4B11_010413   Aspergillus flavus AF13 QMW46934.1    
 G4B11_002507   Aspergillus flavus AF13 QMW39227.1    
 AFCA_005162   Aspergillus flavus CA14 UDD57662.1    
 AFCA_011147   Aspergillus flavus CA14 UDD63896.1    
 AFCA_002608   Aspergillus flavus CA14 UDD54963.1    
 AFCA_003853   Aspergillus flavus CA14 UDD56303.1    
 AFCA_009464   Aspergillus flavus CA14 UDD62135.1    
 F9C07_6256   Aspergillus flavus NRRL 3357 QRD84147.1    
 F9C07_5243   Aspergillus flavus NRRL 3357 QRD91188.1    
 F9C07_2282731   Aspergillus flavus NRRL 3357 QRD86869.1    
 F9C07_9699   Aspergillus flavus NRRL 3357 QRD81492.1    
 F9C07_2291   Aspergillus flavus NRRL 3357 QRD82782.1    
 G4B84_003589   Aspergillus flavus NRRL3357 QMW28300.1    
 G4B84_002428   Aspergillus flavus NRRL3357 QMW27139.1    
 G4B84_005718   Aspergillus flavus NRRL3357 QMW30383.1    
 G4B84_010353   Aspergillus flavus NRRL3357 QMW34862.1    
 G4B84_008070   Aspergillus flavus NRRL3357 QMW32639.1    
 30223   Aspergillus flavus NRRL3357 (Aspfl1)      
 36672   Aspergillus flavus NRRL3357 (Aspfl1)      
 31170   Aspergillus flavus NRRL3357 (Aspfl1)      
 37704   Aspergillus flavus NRRL3357 (Aspfl1)      
 29322   Aspergillus flavus NRRL3357 (Aspfl1)      
 2282731   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)      
 5243   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)      
 6256   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)      
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