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Glycoside Hydrolase Family 12

Known Activitiesendoglucanase (EC 3.2.1.4); xyloglucan hydrolase (EC 3.2.1.151); β-1,3-1,4-glucanase (EC 3.2.1.73); xyloglucan endotransglycosylase (EC 2.4.1.207)
Mechanism Retaining
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesHOMSTRAD; InterPro; PFAM;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (446); Uniprot accession (198); PDB accession (27); 3D entries (10); cryst (1)
Summary
All (283) Archaea (46) Bacteria (141) Eukaryota (96) Structure (10 - 1 cryst) Characterized (66)
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 xyloglucanase 2 (XEG2) (fragment)   Aspergillus aculeatus AAO20340.1 O94218  
 endo-β-1,4-glucanase 1 (FI CM-cellulase;FI-CMCase) 3.2.1.4 Aspergillus aculeatus F-50 AAR63632.1
AAR67685.1
ABJ29216.1
ACP76235.1
BAA00435.1
CAA36757.1		 P22669.1 cryst
 endo-β-1,4-glucanase (xyloglucan-specific) (XEG1) 3.2.1.151 Aspergillus aculeatus KSM 510 AAD02275.1 O94218  
 endoglucanase (Cel12B) 3.2.1.4 Aspergillus kawachii IFO 4308 AAM77715.1
AAR63634.1
AAR67687.1
ABJ29218.1
ACP76237.1		 Q8NJY2  
 endo-β-1,4-glucanase (CekA) 3.2.1.4 Aspergillus kawachii IFO 4308 AAR63633.1
AAR67686.1
ABJ29217.1
ACP76236.1
BAA02297.1		 Q12679  
 endo-β-1,4-glucanase (xyloglucan-specific) (AN0452.2) 3.2.1.151 Aspergillus nidulans FGSC A4 ABF50842.1
EAA66551.1		    
 endoglucanase (EglA)   Aspergillus niger ATCC 10574 ADC84000.1 D3YNY2  
 endo-β-1,4-glucanase (EglA) 3.2.1.4 Aspergillus niger CBS 120.49 / N400 AAE60101.1
AAE84291.1
CAA03652.1
CAA03657.1
CAA11964.1
CAG17891.1		 O74705 1KS4[A]
1KS5[A]
 An03g05530   Aspergillus niger CBS 513.88 CAG17892.1
CAK38314.1		 A2QH44  
 An01g03340   Aspergillus niger CBS 513.88 CAK36874.1 A2Q877  
 An03g05380   Aspergillus niger CBS 513.88 CAK38300.1 A2QH30  
 endo-β-1,4-glucanase (EglA;An14g02760) 3.2.1.4 Aspergillus niger CBS 513.88 CAK46524.1 A2R322  
 xyloglucan-specific endo-β-1,4-glucanase (Xeg12A) 3.2.1.151 Aspergillus niger N402 ABF46829.1 A1XP58  
 endoglucanase A (EglA)   Aspergillus niger VTCC F-021 / VTCC-F021 ADD12042.1 D3YC02  
 endo-β-1,4-glucanase (CelA) 3.2.1.4 Aspergillus oryzae KBN616 AAR63635.1
AAR67688.1
ABJ29219.1
ACP76238.1
BAA22588.1		 O13454  
 AO090003000905   Aspergillus oryzae RIB40 BAE58022.1    
 endo-β-1,4-glucanase (CelA;AO090026000102) 3.2.1.4 Aspergillus oryzae RIB40 BAE59597.1    
 AO090701000185   Aspergillus oryzae RIB40 BAE61926.1    
 AO090038000175   Aspergillus oryzae RIB40 BAE64005.1    
 endo-β-1,4-glucanase (AuCel12A) (Cel12A)   Aspergillus usamii E001 AEL12376.1    
 endo-β-1,4-glucanase (EGIII) 3.2.1.4 Bionectria ochroleuca AAR63642.1
AAR67695.1
ABJ29226.1
ACP76245.1		    
 endoglucanase (Cel12A) 3.2.1.4 Bionectria ochroleuca 1003 AAM77706.1 Q8NJZ1  
 endoglucanase (Cel12B) 3.2.1.4 Bionectria ochroleuca 1003 AAM77707.1
AAR63643.1
AAR67696.1
ABJ29227.1
ACP76246.1		 Q8NJZ0  
 endoglucanase (Cel12C) 3.2.1.4 Bionectria ochroleuca 1003 AAM77708.1
AAR63644.1
AAR67697.1
ABJ29228.1
ACP76247.1		 Q8NJY9  
 endoglucanase (Cel12D) 3.2.1.4 Bionectria ochroleuca 1003 AAM77709.1
AAR63645.1
AAR67698.1
ABJ29229.1
ACP76248.1		 Q8NJY8  
 glycoside hydrolase family 12 protein (Bofut4_p031650.1)   Botryotinia fuckeliana CCD49289.1    
 glycoside hydrolase family 12 protein (Bofut4_p021270.1)   Botryotinia fuckeliana CCD51821.1    
 glycoside hydrolase family 12 protein (Bofut4_p008250.1)   Botryotinia fuckeliana CCD45108.1    
 Bofut4_p039820.1   Botryotinia fuckeliana CCD47080.1    
 glycoside hydrolase family 12 protein (Bofut4_p124780.1) (fragment)   Botryotinia fuckeliana CCD54430.1    
 endoglucanase (Cel12A) 3.2.1.4 Chaetomium brasiliense CBS 140.50 AAM77701.1
AAR63638.1
AAR67691.1
ABJ29222.1
ACP76241.1		 Q8NJZ6  
 endoglucanase (EG3; EG III) 3.2.1.4 Chrysosporium lucknowense AAQ38148.1
ACH15006.1		    
 mixed β-1,3-1,4-glucanase (Mlg2) 3.2.1.73 Cochliobolus carbonum AAF65311.1 Q9P8N6  
 endo-β-1,4-glucanase (C173)   Corynascus heterothallicus CBS 117.65 AAN94974.1    
 orf   Diaphorina citri ABG82005.1 Q0PXV4  
 endoglucanase (Cel12A) 3.2.1.4 Emericella desertorum CBS 653.73 AAM77702.1
AAR63647.1
AAR67700.1
ABJ29231.1
ACP76250.1		 Q8NJZ5  
 endoglucanase II (EG-II;Eg2;EG35) (Cel12) 3.2.1.4 Fomitopsis palustris FFPRI 0507 BAF49602.1 A4PID1  
 endoglucanase (Cel12A) 3.2.1.4 Fusarium equiseti CBS 185.34 AAM77703.1
AAR63639.1
AAR67692.1
ABJ29223.1
ACP76242.1		 Q8NJZ4  
 endo-β-1,4-glucanase (Cel12g;GtCel12A) (Cel12A) 3.2.1.4 Gloeophyllum trabeum ATCC 11539 AEJ35167.1
AEM23897.1		 P84196  
 endoglucanase (Cel12A) 3.2.1.4 Humicola grisea ATCC 22081 AAM77714.2
AAR63636.1
AAR63637.1
AAR67689.1
AAR67690.1
ABJ29220.1
ABJ29221.1
ACP76239.1
ACP76240.1		 Q8NJY3 1OLR[A]
1UU4[A]
1UU5[A]
1UU6[A]
1W2U[A]
 endo-β-1,4-glucanase III (Egl3;EGIII;EG III;EG3) (Cel12A) 3.2.1.4 Hypocrea jecorina QM9414 AAE59774.1
AAE59775.1
AAN19479.1
AAN19480.1
AAO95538.1
AAO95539.1
AAQ24888.1
AAQ42100.1
AAQ42101.1
AAR60524.1
AAR63629.1
AAR63630.1
AAR67682.1
AAR67683.1
ABE22099.1
ABJ29213.1
ABJ29214.1
ABV71388.1
ACP76232.1
ACP76233.1
BAA20140.1		 O00095 1H8V[A,B,C,D,E,F]
1OA2[A,B,C,D,E,F]
1OLQ[A,B]
 endoglucanase (Cel12A) 3.2.1.4 Hypocrea koningii ATCC 2613 AAM77712.1 Q8NJY5  
 endogluanase III   Hypocrea pseudokoningii ABM90985.1 A2TDD5  
 endoglucanase I   Hypocrea rufa AAS18313.1 Q6QTF2  
 endoglucanase (Cel12A) 3.2.1.4 Hypocrea rufa ATCC 26802 AAM77713.1 Q8NJY4  
 endoglucanase (Cel12A) 3.2.1.4 Hypocrea schweinitzii ATCC 66965 AAE59776.1
AAM77711.1
AAN19481.1
AAO95540.1
AAQ42102.1
AAR63631.1
AAR67684.1
ABJ29215.1
ACP76234.1		 Q8NJY6 1OA3[A,B,C,D]
 ORF   Leptosphaeria maculans v23.1.3 CBX91934.1 E5R4G6  
 ORF   Leptosphaeria maculans v23.1.3 CBX95838.1 E4ZW62  
 ORF   Leptosphaeria maculans v23.1.3 CBX99520.1 E5A7C5  
 xyloglucan endotransglycosylase (XET) 2.4.1.207 Macrophomina phaseolina AAN89225.1
AAS22565.1		    
 endo-β-1,3-1,4-glucanase (MoCel12A;MG00677.4) (Cel12A) 3.2.1.73 Magnaporthe grisea 70-15 XP_368567.1    
 endo-β-1,3-1,4-glucanase (MoCel12C;MG10972.4) (Cel12C) 3.2.1.73 Magnaporthe grisea 70-15 XP_361895.1    
 endo-β-1,3-1,4-glucanase (MoCel12B;MG08537.4) (Cel12B) 3.2.1.73 Magnaporthe grisea 70-15 XP_362900.1    
 xyloglucanase 3.2.1.151 Malbranchea cinnamomea AAO95986.1    
 MYCTH_109444   Myceliophthora thermophila ATCC 42464 AEO60532.1    
 endoglucanase (Cel12A) 3.2.1.4 Nectria ipomoeae CBS 203.32 AAM77704.1
AAR63640.1
AAR67693.1
ABJ29224.1
ACP76243.1		 Q8NJZ3  
 endoglucanase (Cel12B) 3.2.1.4 Nectria ipomoeae CBS 203.32 AAM77705.1
AAR63641.1
AAR67694.1
ABJ29225.1
ACP76244.1		 Q8NJZ2  
 NCU08227.1   Neurospora crassa OR74A XP_328933.1    
 endo-β-1,4-glucanase 3 (Egl3) 3.2.1.4 Penicillium canescens VKPM F178      
 Pc16g06060   Penicillium chrysogenum Wisconsin 54-1255 CAP93276.1 B6H8I9  
 Pc16g08690   Penicillium chrysogenum Wisconsin 54-1255 CAP93539.1 B6H7Y5  
 Pc20g07340   Penicillium chrysogenum Wisconsin 54-1255 CAP86063.1 B6HDE0  
 Cel12 (fragment) (Cel12)   Penicillium decumbens 114-2 ACH57440.1 B5M080  
 endoglucanase 28 (Cel12A) 3.2.1.4 Phanerochaete chrysosporium K3 AAU12276.1 Q66NB6  
 endoglucanase (Egl12.1;Cell 12A) (Cel12A)   Phytophthora infestans ABG91065.1 Q0PQ33  
 endoglucanase (EGL12-H) (Cel12H)   Phytophthora ramorum ABB22039.1 Q30BY2  
 endoglucanase (EGL12-G) (Cel12G)   Phytophthora ramorum ABB22038.1 Q30BY3  
 endoglucanase (EGL12-F) (Cel12F)   Phytophthora ramorum ABB22037.1 Q30BY4  
 endoglucanase (EGL12-E) (Cel12E)   Phytophthora ramorum ABB22036.1 Q30BY5  
 endoglucanase (EGL12-D) (Cel12D)   Phytophthora ramorum ABB22035.1 Q30BY6  
 endoglucanase (EGL12-C) (Cel12C)   Phytophthora ramorum ABB22034.1 Q30BY7  
 endoglucanase (EGL12-B) (Cel12B)   Phytophthora ramorum ABB22033.1 Q30BY8  
 endoglucanase (EGL12-A) (Cel12A)   Phytophthora ramorum ABB22032.1 Q30BY9  
 endoglucanase (EGL12-B)   Phytophthora sojae AAT66504.1 Q6DTZ0  
 endoglucanase (EGL12-L) (fragment)   Phytophthora sojae ABB92621.1 Q2V8M9  
 endoglucanase (EGL12-I) (Cel12I)   Phytophthora sojae ABB22031.1 Q30BZ0  
 endoglucanase (EGL12-H) (Cel12H)   Phytophthora sojae ABB22030.1 Q30BZ1  
 endoglucanase (EGL12-G) (Cel12G)   Phytophthora sojae ABB22029.1 Q30BZ2  
 endoglucanase (EGL12-F) (Cel12F)   Phytophthora sojae ABB22028.1 Q30BZ3  
 endoglucanase (EGL12-E) (Cel12E)   Phytophthora sojae ABB22027.1 Q30BZ4  
 endoglucanase (EGL12-D) (Cel12D)   Phytophthora sojae ABB22026.1 Q30BZ5  
 endoglucanase (EGL12-C) (Cel12C)   Phytophthora sojae ABB22025.1 Q30BZ6  
 endoglucanase (EGL12-A) (Cel12A)   Phytophthora sojae ABB22024.1 Q30BZ7  
 PIIN_09685   Piriformospora indica CCA75695.1    
 Pa_4_6020   Podospora anserina S mat+ CAP66908.1 B2APW9  
 Pa_7_3370   Podospora anserina S mat+ CAP68354.1 B2AVD0  
 endoglucanase (Cel3A;CMCase3a;CMCase IIIa) 3.2.1.4 Polyporus arcularius 69B-8 BAD98315.1 Q50LE3  
 endo-β-1,4-glucanase (PpCel12A) (Cel12A)   Postia placenta Mad-698-R ADH51731.1 D7REW4  
 endoglucanase (Cel12A)   Stachybotrys chartarum CECT 20565 CAL48345.1 Q08HM8  
 endoglucanase (Cel12A) 3.2.1.4 Stachybotrys echinata CBS 304.54 AAM77710.1
AAR63646.1
AAR67699.1
ABJ29230.1
ACP76249.1		 Q8NJY7  
 endocellulase (Eg12)   Thanatephorus cucumeris AG-1-IA ACT78560.1
ACT78705.1		 C7AGU1  
 THITE_2043508   Thielavia terrestris NRRL 8126 AEO67160.1    
 THITE_2117762   Thielavia terrestris NRRL 8126 AEO68296.1    
 THITE_121780   Thielavia terrestris NRRL 8126 AEO69079.1    
 Sequence 105788 from patent US 7214786   Triticum aestivum ABT18318.1
ABT18319.1		    
 unknown (possible fungal contaminant)   Zea mays ACG26880.1 B6SPU7  




Last update: 2012-01-31 © Copyright 1998-2012
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