Glycoside Hydrolase Family 109

Activities in Family	α-N-acetylgalactosaminidase (EC 3.2.1.49); β-N-acetylhexosaminidase (EC 3.2.1.52);
Mechanism	Other a,e
3D Structure Status	Rossmann fold
Catalytic Nucleophile/Base	Not applicable
Catalytic Proton Donor	None
Note	Created following Liu et al. (2007) Nature Biotechnol 25:454-64 (PMID: 17401360); the enzymes in this family display an unusual mechanism involving NAD+
External resources	CAZypedia;
Statistics	GenBank accession (2404); Uniprot accession (9); PDB accession (3); 3D entries (2); cryst (0)

Summary

Download GH109 (2372) Taxonomic display Structure (2) Characterized (8)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
FH965_35715		Streptomyces spectabilis NRRL 2792	QDQ15245.1
LDH80_33515		Streptomyces tanashiensis Kala	UZX25326.1
AY578_32115		Streptomyces thermocarboxydus K155	UVT13488.1
GBW32_32875		Streptomyces tsukubensis AT3	QFR96968.1
B7R87_03110		Streptomyces tsukubensis NRRL 18488	AZK92981.1
STSU_030720		Streptomyces tsukubensis NRRL18488	QKM70858.1
MMF93_30725		Streptomyces tubbatahanensis DSD3025	UNT00352.1
STRTU_000847		Streptomyces tubercidicus DSM 40261	WAU10731.1
DEJ45_31465		Streptomyces venezuelae ATCC 10595	QES16459.1
SVEN_0788		Streptomyces venezuelae ATCC 10712	CCA54075.1 QER97608.1
DEJ47_02025		Streptomyces venezuelae ATCC 14583	QES25399.1
DEJ48_36245		Streptomyces venezuelae ATCC 14584	QES38143.1
DEJ49_02070		Streptomyces venezuelae ATCC 14585	QES39922.1
DEJ46_34390		Streptomyces venezuelae ATCC 15068	QES23588.1
BN2537_3525		Streptomyces venezuelae ATCC 15439	CUM37280.1
BN2537_14779		Streptomyces venezuelae ATCC 15439	CUM42907.1
AQF52_1201		Streptomyces venezuelae ATCC 15439	ALO06797.1
AQF52_6550		Streptomyces venezuelae ATCC 15439	ALO12143.1
DEJ44_03695		Streptomyces venezuelae ATCC 21113	QES04795.1
U0M97_05940		Streptomyces venezuelae SvWT	WRK35468.1
U0M97_33050		Streptomyces venezuelae SvWT	WRK40459.1
SVTN_05420		Streptomyces vietnamensis GIM4.0001	AJF63937.1
N6Q81_32535		Streptomyces vinaceusdrappus AC-40	UXI82451.1
R2E43_36485		Streptomyces violaceoruber CGMCC 4.1801	WOZ02665.1
B1H20_02910		Streptomyces violaceoruber S21	ARF60452.1
CP969_06240		Streptomyces viridosporus T7A ATCC 39115	QEU84332.1
IAG42_31050		Streptomyces xanthii CRXT-Y-14	QNS07605.1
MOV08_07950		Streptomyces yunnanensis P86	WEB39213.1
G3M56_014215		Sulfuriroseicoccus oceanibius T37	QQL44996.1
N4264_19385		Tahibacter amnicola W38	UXI66900.1
TF3313_0738		Tannerella forsythia 3313	BAR48300.1
BFO_0765 (NagA)		Tannerella forsythia 92A2	AEW21064.1
α-N-acetylgalactosaminidase	3.2.1.49	Tannerella forsythia ATCC43037	CAJ01380.1	A4Q8G1
TFKS16_1358		Tannerella forsythia KS16	BAR51620.1
PG911_05705		Tenacibaculum ovolyticum 20-4135-2	WBX77753.1
PG912_05125 (fragment)		Tenacibaculum retecalamus 18-3228-7B	WBX72151.1
PG912_05120 (fragment)		Tenacibaculum retecalamus 18-3228-7B	WBX72150.1
D6T69_07580		Tenacibaculum singaporense DSM 106434	AZJ35389.1
SAMN05444167_2123		Terriglobus roseus GAS232	SDF34494.1
AciPR4_1438		Terriglobus saanensis SP1PR4	ADV82261.1
AciPR4_2505		Terriglobus saanensis SP1PR4	ADV83284.1
H9L17_07190		Thermomonas brevis KACC 16975	QNN47901.1
G7079_12875		Thermomonas sp. HDW16	QIL21556.1
P0M28_04310		Tunicatimonas pelagia NBRC 107804	WKN44189.1
α-N-acetylgalactosaminidase, glycoside hydrolase family GH109 (fragment)		uncultured bacterium	AOE10458.1
α-N-acetylgalactosaminidase, glycoside hydrolase family GH109		uncultured bacterium	AOE10342.1
Gfo/Idh/MocA family oxidoreductase (fragment)		uncultured bacterium	AUN36281.1
oxidoreductase, GfoIdhMocA family		uncultured bacterium	AWJ66095.1
ORF		uncultured bacterium contig00027	AGS53455.1
ORF		uncultured bacterium Contig39	AHF25437.1
RF679_18095		Undibacterium sp. 20NA77.5	WMW80529.1
RF679_18085 (fragment)		Undibacterium sp. 20NA77.5	WMW80527.1
OPR71_03660 (fragment)		Vibrio alginolyticus AUSMDU00064140	WAE57083.1
Cytochrome c-type biogenesis protein DsbD (plasmid) (fragment)		Vibrio alginolyticus Vb2134	UUL99969.1
Cytochrome c-type biogenesis protein DsbD (plasmid) (fragment)		Vibrio alginolyticus Vb2175	UUC08768.1
WPG_2635		Winogradskyella sp. PG-2	BAO76865.1
NG831_03170		Xanthomonas sacchari HR1-32	UYK67217.1
NG825_03260		Xanthomonas sacchari HR3-46	UYK77393.1
NG824_17820		Xanthomonas sacchari JR3-14	UYK88311.1
NG829_03230		Xanthomonas sacchari LT6-16-1	UYK81340.1
NG827_03260		Xanthomonas sacchari LT6-2	UYK85446.1
SB85_15845		Xanthomonas sacchari R1	AJC46990.1
NG828_03300		Xanthomonas sacchari YT9-19-2	UYK73375.1
CJ027_003275		Xanthomonas sontii PPL1	UZK05846.1
MQE36_09285		Zhouia spongiae HN-Y44	UNY97290.1
zobellia_4126 (NagA)		Zobellia galactanivorans DsijT	CAZ98261.1
Q5W13_21255		Zobellia laminariae AS94	WKX76076.1
ZPR_2895		Zunongwangia profunda SM-A87	ADF53215.1
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