Glycoside Hydrolase Family 109

Activities in Familyα-N-acetylgalactosaminidase (EC 3.2.1.49)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNone
NoteCreated following Liu et al. (2007) Nature Biotechnol 25:454-64 (PMID: 17401360); the enzymes in this family display an unusual mechanism involving NAD+
External resourcesCAZypedia;
Statistics GenBank accession (496); Uniprot accession (77); PDB accession (2); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 N-acetylgalactosaminidase 3.2.1.49 Arenibacter latericius KMM426 ADM26828.1 E1AXI3  
 α-N-acetylgalactosaminidase (NagA) 3.2.1.49 Elizabethkingia meningoseptica ATCC 13253 CAJ01375.1 A2AWV6  
 α-N-acetylgalactosaminidase (NagA) 3.2.1.49 Elizabethkingia meningoseptica ATCC 33958 CAJ01376.1 A4Q8F7 2IXA[A]
2IXB[A]
 α-N-acetylgalactosaminidase (NagA) 3.2.1.49 Elizabethkingia meningoseptica CGMCC 2198 ACA51901.1 B1PU63  
 α-N-acetylgalactosaminidase (NagA) 3.2.1.49 Shewanella oneidensis ATCC70050 CAJ01377.1 Q8ECL7  
 α-N-acetylgalactosaminidase 3.2.1.49 Tannerella forsythia ATCC43037 CAJ01380.1 A4Q8G1  
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