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Glycoside Hydrolase Family 109

Activities in Familyα-N-acetylgalactosaminidase (EC 3.2.1.49);
β-N-acetylhexosaminidase (EC 3.2.1.52);
Mechanism Other a,e
3D Structure StatusRossmann fold
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNone
NoteCreated following Liu et al. (2007) Nature Biotechnol 25:454-64 (PMID: 17401360); the enzymes in this family display an unusual mechanism involving NAD+
External resourcesCAZypedia;
Statistics GenBank accession (2404); Uniprot accession (9); PDB accession (3); 3D entries (2); cryst (0)
Summary
Download GH109 (2372) Taxonomic display Structure (2) Characterized (8)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CS374_08235   Porphyromonas gingivalis KCOM 2798 ATS05511.1    
 CS387_03790   Porphyromonas gingivalis KCOM 2799 ATS07519.1    
 CS388_01090   Porphyromonas gingivalis KCOM 2800 ATS09332.1    
 CS543_04715   Porphyromonas gingivalis KCOM 2801 ATS11407.1    
 CS544_09860   Porphyromonas gingivalis KCOM 2802 ATR91605.1    
 CS545_03485   Porphyromonas gingivalis KCOM 2803 ATR93500.1    
 CS546_01810   Porphyromonas gingivalis KCOM 2804 ATR95539.1    
 CS548_08195   Porphyromonas gingivalis KCOM 2805 ATR97675.1    
 CS550_02745   Porphyromonas gingivalis KCOM 3001 ATR99538.1    
 CS549_00915   Porphyromonas gingivalis KCOM 3131 ATS01448.1    
 QP877_06590   Porphyromonas gingivalis LyEC02 WIM90767.1    
 KC155_03525   Porphyromonas gingivalis LyG-1 QUI92176.1    
 KDH82_03535   Porphyromonas gingivalis LyG-2 QUI90231.1    
 CF002_1790 (MviM)   Porphyromonas gingivalis TDC 60 AUR47537.1    
 PGTDC60_1790   Porphyromonas gingivalis TDC60 BAK25939.1    
 MCS25_03005   Porphyromonas gingivalis W50 USI98402.1    
 MCS27_03000   Porphyromonas gingivalis W50/BE1 USI96492.1    
 MCS24_05005   Porphyromonas gingivalis W50/BR1 USI94942.1    
 CF003_0664 (MviM)   Porphyromonas gingivalis W83 AUR45804.1    
 PG0664   Porphyromonas gingivalis W83 AAQ65842.1
NP_904943.1		    
 NF669_06905   Porphyromonas gingivalis yellow WKD51989.1    
 CE91St14_00660   Porphyromonas somerae CE91-St14 BDE81038.1    
 J4862_04750 (fragment)   Porphyromonas sp. oral taxon 275 W7780 QUB42324.1    
 J4862_03370   Porphyromonas sp. oral taxon 275 W7780 QUB43667.1    
 QP022_09425   Prevotella bivia PLW0727 WIL18498.1    
 TOH2715_18320   Prevotella bivia TOH-2715 BFG45425.1    
 J5A64_07925   Prevotella denticola F0105 QUI92926.1    
 J4866_11925   Prevotella denticola F0115 QUB93910.1    
 J4855_05970   Prevotella denticola F0119 QUB91984.1    
 J4860_07580   Prevotella denticola F0288 QUB89474.1    
 HMPREF9137_1914   Prevotella denticola F0289 AEA21793.1    
 DYJ25_10780   Prevotella denticola KCOM 1525 AXV50286.1    
 ADJ77_09775   Prevotella fusca JCM 17724 W1435 AKU70101.1    
 J5A51_05600   Prevotella fusca JCM 17724 W1435 QUB85713.1    
 J5A62_04450   Prevotella histicola F0411 QUB83079.1    
 CRM71_05695   Prevotella jejuni CD3_33 AUI54859.1    
 CRM71_09605   Prevotella jejuni CD3_33 AUI55632.1    
 J5A63_00385   Prevotella jejuni F0106 QUB80970.1    
 J5A63_10455   Prevotella jejuni F0106 QUB82610.1    
 J4857_08695   Prevotella jejuni F0697 QUB78007.1    
 J4857_13030   Prevotella jejuni F0697 QUB79140.1    
 HMPREF0659_A7110   Prevotella melaninogenica ATCC 25845 ADK97129.1    
 HMPREF0659_A6680   Prevotella melaninogenica ATCC 25845 ADK97140.1    
 J5A58_09805   Prevotella melaninogenica F0054 QUB77029.1    
 J5A58_12970   Prevotella melaninogenica F0054 QUB76619.1    
 J5A56_04740   Prevotella melaninogenica F0091 QUB72621.1    
 J5A68_14135   Prevotella melaninogenica F0299 QUB69484.1    
 J5A68_09855   Prevotella melaninogenica F0299 QUB69704.1    
 J5A57_09290   Prevotella melaninogenica F0300 QUB67285.1    
 J5A57_10125   Prevotella melaninogenica F0300 QUB67131.1    
 J5A54_11910   Prevotella melaninogenica F0301 QUB64222.1    
 J4861_04605   Prevotella melaninogenica F0516 QUB60351.1    
 J5A71_08230   Prevotella melaninogenica F0692 QUB59655.1    
 J5A71_11005   Prevotella melaninogenica F0692 QUB59230.1    
 J5A72_11315   Prevotella melaninogenica F0695 QUB57031.1    
 J5A72_08995   Prevotella melaninogenica F0695 QUB57535.1    
 CEP85_07600   Prevotella melaninogenica FDAARGOS_306 ASE18888.1    
 CEP85_10605   Prevotella melaninogenica FDAARGOS_306 ASE18547.1    
 FIU21_00390   Prevotella melaninogenica FDAARGOS_760 QKH87489.1    
 PMEL_200800   Prevotella melaninogenica GAI 07411 BBA30272.1    
 PMEL_200174   Prevotella melaninogenica GAI 07411 BBA29659.1    
 J4864_08180   Prevotella multiformis F0096 QUB72108.1    
 AXF22_11135   Prevotella scopos JCM 17725 W2052 ANR73979.1    
 J4856_00885   Prevotella scopos JCM 17725 W2052 QUB44568.1    
 J4856_02770   Prevotella scopos JCM 17725 W2052 QUB43953.1    
 HMPREF0669_00766   Prevotella sp. oral taxon 299 str. F0039 EFC71061.2    
 J5A66_00680   Prevotella sp. oral taxon 475 F0059 QUB47384.1    
 J5A66_00630   Prevotella sp. oral taxon 475 F0059 QUB47378.1    
 GRF55_10770   Prevotella sp. Rep29 QYR11531.1    
 J5A55_04225   Prevotella veroralis F0319 QUB39974.1    
 K5X82_05830   Prolixibacteraceae bacterium DS1-an-2312 QZT38412.1    
 K5X82_10565   Prolixibacteraceae bacterium DS1-an-2312 QZT35759.1    
 K4L44_03100   Prolixibacteraceae bacterium KCTC 25031 QZE14862.1    
 K4L44_17180   Prolixibacteraceae bacterium KCTC 25031 QZE14221.1    
 KDN43_05905   Proteiniphilum propionicum JNU-WLY501 ULB35566.1    
 KDN43_16030   Proteiniphilum propionicum JNU-WLY501 ULB34434.1    
 KDN43_06000   Proteiniphilum propionicum JNU-WLY501 ULB35583.1    
 PSM36_0685   Proteiniphilum saccharofermentans SCD19513.1    
 PSM36_1563   Proteiniphilum saccharofermentans SCD20383.1    
 KOL64_20600   Providencia rettgeri PreM15758 WJM88397.1    
 Oxidoreductase, Gfo/Idh/MocA family (plasmid) (fragment)   Providencia rettgeri PROV275 URQ57689.1    
 Oxidoreductase, Gfo/Idh/MocA family (plasmid) (fragment)   Providencia rettgeri PROV275 URQ57834.1    
 LOCMHKOF_00148 (DsbD)   Providencia stuartii 41 WHE44031.1    
 MWH14_21095 (fragment)   Providencia stuartii CMC-4104 URE78785.1    
 MWH14_20160 (fragment)   Providencia stuartii CMC-4104 URE78654.1    
 MWH14_20420 (fragment)   Providencia stuartii CMC-4104 URE78690.1    
 MWH14_20355 (fragment)   Providencia stuartii CMC-4104 URE78681.1    
 MWH14_20680 (fragment)   Providencia stuartii CMC-4104 URE78726.1    
 MWH14_20095 (fragment)   Providencia stuartii CMC-4104 URE78645.1    
 MWH14_20615 (fragment)   Providencia stuartii CMC-4104 URE78717.1    
 MWH14_20290 (fragment)   Providencia stuartii CMC-4104 URE78672.1    
 MWH14_20030 (fragment)   Providencia stuartii CMC-4104 URE78636.1    
 MWH14_20810 (fragment)   Providencia stuartii CMC-4104 URE78744.1    
 MWH14_20225 (fragment)   Providencia stuartii CMC-4104 URE78663.1    
 MWH14_20745 (fragment)   Providencia stuartii CMC-4104 URE78735.1    
 MWH14_20985 (fragment)   Providencia stuartii CMC-4104 URE78769.1    
 MWH14_20875 (fragment)   Providencia stuartii CMC-4104 URE78753.1    
 MWH14_20550 (fragment)   Providencia stuartii CMC-4104 URE78708.1    
 MWH14_20485 (fragment)   Providencia stuartii CMC-4104 URE78699.1    
 MXW51_000270 (fragment)   Providencia stuartii p_dmpro_s749a_NDM1 UPF36297.1    
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