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Glycoside Hydrolase Family 109

Activities in Familyα-N-acetylgalactosaminidase (EC 3.2.1.49);
β-N-acetylhexosaminidase (EC 3.2.1.52);
Mechanism Other a,e
3D Structure StatusRossmann fold
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNone
NoteCreated following Liu et al. (2007) Nature Biotechnol 25:454-64 (PMID: 17401360); the enzymes in this family display an unusual mechanism involving NAD+
External resourcesCAZypedia;
Statistics GenBank accession (2403); Uniprot accession (9); PDB accession (3); 3D entries (2); cryst (0)
Summary
Download GH109 (2371) Taxonomic display Structure (2) Characterized (8)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CUB96_10960   Akkermansia muciniphila AMDK-3 AYR31288.1    
 CUB96_04020   Akkermansia muciniphila AMDK-3 AYR30105.1    
 CUC01_02260   Akkermansia muciniphila AMDK-4 AYR32042.1    
 CUC01_07165   Akkermansia muciniphila AMDK-4 AYR32888.1    
 KDJ95_04675   Akkermansia muciniphila AMUC QUF78770.1    
 KDJ95_00075   Akkermansia muciniphila AMUC QUF77926.1    
 α-N-acetylgalactosaminidase (AmGH109B;Amuc_0017) 3.2.1.49 Akkermansia muciniphila ATCC BAA-835 ACD03864.1
QTD80695.1		 B2UL75  
 a/β-N-acetylgalactosaminidase (AmGH109A;Amuc_0920) 3.2.1.49
3.2.1.52		 Akkermansia muciniphila ATCC BAA-835 ACD04752.1
QTD81538.1		 B2UQL7 6T2B[A,B,C,D]
 AKKM5201_00080   Akkermansia muciniphila CBA5201 QAT90460.1    
 AKKM5201_04495   Akkermansia muciniphila CBA5201 QAT91259.1    
 FU653_00075   Akkermansia muciniphila DSM 22959 QEE53452.1    
 FU653_04675   Akkermansia muciniphila DSM 22959 QEE54274.1    
 C1I94_00085   Akkermansia muciniphila EB-AMDK-10 QAA40164.1    
 C1I94_05610   Akkermansia muciniphila EB-AMDK-10 QAA41133.1    
 C1I96_00080   Akkermansia muciniphila EB-AMDK-11 QAA42496.1    
 C1I96_05425   Akkermansia muciniphila EB-AMDK-11 QAA43442.1    
 C1O37_00080   Akkermansia muciniphila EB-AMDK-12 QAA44796.1    
 C1O37_05435   Akkermansia muciniphila EB-AMDK-12 QAA45746.1    
 C1O47_00085   Akkermansia muciniphila EB-AMDK-14 QAA49426.1    
 C1O47_05495   Akkermansia muciniphila EB-AMDK-14 QAA50384.1    
 C1O50_00085   Akkermansia muciniphila EB-AMDK-15 QAA51743.1    
 C1O50_05375   Akkermansia muciniphila EB-AMDK-15 QAA52661.1    
 C1O51_00080   Akkermansia muciniphila EB-AMDK-16 QAA54057.1    
 C1O51_05370   Akkermansia muciniphila EB-AMDK-16 QAA54971.1    
 C1O54_05375   Akkermansia muciniphila EB-AMDK-17 QAA57288.1    
 C1O54_00080   Akkermansia muciniphila EB-AMDK-17 QAA56369.1    
 C1O57_05340   Akkermansia muciniphila EB-AMDK-18 QAA59594.1    
 C1O57_00080   Akkermansia muciniphila EB-AMDK-18 QAA58680.1    
 C1O59_05255   Akkermansia muciniphila EB-AMDK-19 QAA61925.1    
 C1O59_00085   Akkermansia muciniphila EB-AMDK-19 QAA61007.1    
 C1O60_05310   Akkermansia muciniphila EB-AMDK-20 QAA64177.1    
 C1O60_00085   Akkermansia muciniphila EB-AMDK-20 QAA63256.1    
 C1O61_00080   Akkermansia muciniphila EB-AMDK-21 QAA65505.1    
 C1O61_05395   Akkermansia muciniphila EB-AMDK-21 QAA66438.1    
 C1O62_05315   Akkermansia muciniphila EB-AMDK-22 QAA68690.1    
 C1O62_00080   Akkermansia muciniphila EB-AMDK-22 QAA67776.1    
 DMI71_05560   Akkermansia muciniphila EB-AMDK-23 QHV53359.1    
 DMI71_00075   Akkermansia muciniphila EB-AMDK-23 QHV52381.1    
 DMI72_00075   Akkermansia muciniphila EB-AMDK-24 QHV54748.1    
 DMI72_05635   Akkermansia muciniphila EB-AMDK-24 QHV55726.1    
 DMI73_00075   Akkermansia muciniphila EB-AMDK-25 QHV57123.1    
 DMI73_05585   Akkermansia muciniphila EB-AMDK-25 QHV58098.1    
 DMI74_11270   Akkermansia muciniphila EB-AMDK-26 QHV61464.1    
 DMI74_05780   Akkermansia muciniphila EB-AMDK-26 QHV60486.1    
 C5N96_05450   Akkermansia muciniphila EB-AMDK-27 QHV09254.1    
 C5N96_00080   Akkermansia muciniphila EB-AMDK-27 QHV08307.1    
 C5N97_05425   Akkermansia muciniphila EB-AMDK-28 QHV11540.1    
 C5N97_00085   Akkermansia muciniphila EB-AMDK-28 QHV10597.1    
 C5O09_00090   Akkermansia muciniphila EB-AMDK-29 QHV12890.1    
 C5O09_05080   Akkermansia muciniphila EB-AMDK-29 QHV13767.1    
 C5O10_05110   Akkermansia muciniphila EB-AMDK-30 QHV16235.1    
 C5O10_00090   Akkermansia muciniphila EB-AMDK-30 QHV15351.1    
 C5O11_05420   Akkermansia muciniphila EB-AMDK-31 QHV18764.1    
 C5O11_00080   Akkermansia muciniphila EB-AMDK-31 QHV17817.1    
 C5O12_05265   Akkermansia muciniphila EB-AMDK-33 QHV21095.1    
 C5O12_00085   Akkermansia muciniphila EB-AMDK-33 QHV20177.1    
 C5O13_05255   Akkermansia muciniphila EB-AMDK-34 QHV23344.1    
 C5O13_00085   Akkermansia muciniphila EB-AMDK-34 QHV22428.1    
 C5O14_05270   Akkermansia muciniphila EB-AMDK-35 QHV27826.1    
 C5O14_00085   Akkermansia muciniphila EB-AMDK-35 QHV26904.1    
 C5O15_00080   Akkermansia muciniphila EB-AMDK-36 QHV24667.1    
 C5O15_05280   Akkermansia muciniphila EB-AMDK-36 QHV25586.1    
 C5O16_00080   Akkermansia muciniphila EB-AMDK-37 QHV29154.1    
 C5O16_05500   Akkermansia muciniphila EB-AMDK-37 QHV30114.1    
 C5O17_00080   Akkermansia muciniphila EB-AMDK-38 QHV31527.1    
 C5O17_05505   Akkermansia muciniphila EB-AMDK-38 QHV32484.1    
 DMI75_05665   Akkermansia muciniphila EB-AMDK-39 QHV75245.1    
 DMI75_00090   Akkermansia muciniphila EB-AMDK-39 QHV74239.1    
 DMI76_05665   Akkermansia muciniphila EB-AMDK-40 QHV62879.1    
 DMI76_00090   Akkermansia muciniphila EB-AMDK-40 QHV61872.1    
 DMI77_00090   Akkermansia muciniphila EB-AMDK-41 QUY58196.1    
 DMI77_05685   Akkermansia muciniphila EB-AMDK-41 QUY59202.1    
 DMI78_05505   Akkermansia muciniphila EB-AMDK-46 QHV65389.1    
 DMI78_00085   Akkermansia muciniphila EB-AMDK-46 QHV64416.1    
 DMI79_05525   Akkermansia muciniphila EB-AMDK-47 QHV67834.1    
 DMI79_00080   Akkermansia muciniphila EB-AMDK-47 QHV66866.1    
 DMI80_05510   Akkermansia muciniphila EB-AMDK-48 QHV70305.1    
 DMI80_00085   Akkermansia muciniphila EB-AMDK-48 QHV69330.1    
 DMI81_00085   Akkermansia muciniphila EB-AMDK-49 QHV71784.1    
 DMI81_05510   Akkermansia muciniphila EB-AMDK-49 QHV72759.1    
 DFS30_05160   Akkermansia muciniphila EB-AMDK-5 QHV48664.1    
 DFS30_00085   Akkermansia muciniphila EB-AMDK-5 QHV47768.1    
 DMI67_04805   Akkermansia muciniphila EB-AMDK-6 QHV50861.1    
 DMI67_10185   Akkermansia muciniphila EB-AMDK-6 QHV51819.1    
 C1I88_00075   Akkermansia muciniphila EB-AMDK-7 QAA35436.1    
 C1I88_05225   Akkermansia muciniphila EB-AMDK-7 QAA36343.1    
 C1I90_05440   Akkermansia muciniphila EB-AMDK-8 QAA38740.1    
 C1I90_00085   Akkermansia muciniphila EB-AMDK-8 QAA37789.1    
 SI90_11890   Akkermansia muciniphila H2 QAR50989.1    
 SI90_06500   Akkermansia muciniphila H2 QAR50198.1    
 AKMU_00180 (Naga_1)   Akkermansia muciniphila JCM 30893 BBP47272.1    
 AKMU_07700 (Naga_2)   Akkermansia muciniphila JCM 30893 BBP48024.1    
 GXM23_04160   Akkermansia muciniphila JCM30893 QIA35646.1    
 GXM23_00090   Akkermansia muciniphila JCM30893 QIA34902.1    
 J4Z34_00075   Akkermansia muciniphila KGMB01988 QTF05294.1    
 J4Z34_05055   Akkermansia muciniphila KGMB01988 QTF06213.1    
 J4Z33_00075   Akkermansia muciniphila KGMB01989 QTF00672.1    
 J4Z33_05045   Akkermansia muciniphila KGMB01989 QTF01588.1    
 J4Z36_00075   Akkermansia muciniphila KGMB01990 QTF02981.1    
 J4Z36_05050   Akkermansia muciniphila KGMB01990 QTF03900.1    
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