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Glycoside Hydrolase Family 109

Activities in Familyα-N-acetylgalactosaminidase (EC 3.2.1.49);
β-N-acetylhexosaminidase (EC 3.2.1.52);
Mechanism Other a,e
3D Structure StatusRossmann fold
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNone
NoteCreated following Liu et al. (2007) Nature Biotechnol 25:454-64 (PMID: 17401360); the enzymes in this family display an unusual mechanism involving NAD+
External resourcesCAZypedia;
Statistics GenBank accession (2403); Uniprot accession (9); PDB accession (3); 3D entries (2); cryst (0)
Summary
Download GH109 (2371) Taxonomic display Structure (2) Characterized (8)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 NXW85_09060   Bacteroides caccae BFG-104 UVQ08325.1    
 NXW23_04375   Bacteroides caccae BFG-474 UVQ97607.1    
 NXW23_01270   Bacteroides caccae BFG-474 UVQ98651.1    
 NXW23_08010   Bacteroides caccae BFG-474 UVQ98247.1    
 NXW23_07895   Bacteroides caccae BFG-474 UVQ98698.1    
 INE72_01909   Bacteroides caccae CL03T12C61 QUU07859.1    
 INE72_01078   Bacteroides caccae CL03T12C61 QUU07042.1    
 INE72_01929   Bacteroides caccae CL03T12C61 QUU07879.1    
 INE72_00405   Bacteroides caccae CL03T12C61 QUU06380.1    
 I6I54_15395   Bacteroides caccae FDAARGOS_1097 QQT79919.1    
 I6I54_15290   Bacteroides caccae FDAARGOS_1097 QQT77615.1    
 I6I54_00340   Bacteroides caccae FDAARGOS_1097 QQT78254.1    
 I6I54_02855   Bacteroides caccae FDAARGOS_1097 QQT78718.1    
 I6J49_10315   Bacteroides caccae FDAARGOS_1219 QRP56502.1    
 I6J49_13620   Bacteroides caccae FDAARGOS_1219 QRP59786.1    
 I6J49_07795   Bacteroides caccae FDAARGOS_1219 QRP59398.1    
 I6J49_13725   Bacteroides caccae FDAARGOS_1219 QRP57141.1    
 RJT08_08605   Bacteroides caccae H-1617 WOG13401.1    
 RJT08_05105   Bacteroides caccae H-1617 WOG12466.1    
 RJT08_08710   Bacteroides caccae H-1617 WOG13135.1    
 RJT08_02430   Bacteroides caccae H-1617 WOG13356.1    
 A4V03_02670   Bacteroides caecimuris I48 ANU59644.1
QQR19214.1
UQA32230.1		    
 K6V21_22750   Bacteroides cellulosilyticus BFG-250 UBD69161.1    
 NXW88_12735   Bacteroides cellulosilyticus BFG-371 UVP53667.1    
 NXW88_02675   Bacteroides cellulosilyticus BFG-371 UVP51864.1    
 INE78_02812   Bacteroides cellulosilyticus CL06T03C01 QUT90820.1    
 INE78_01554   Bacteroides cellulosilyticus CL06T03C01 QUT89581.1    
 INE78_05049   Bacteroides cellulosilyticus CL06T03C01 QUT93023.1    
 NWT25_21510   Bacteroides cellulosilyticus PL2022 UWZ88891.1    
 NWT25_02580   Bacteroides cellulosilyticus PL2022 UWZ90134.1    
 NWT25_12460   Bacteroides cellulosilyticus PL2022 UWZ87186.1    
 BcellWH2_04176   Bacteroides cellulosilyticus WH2 ALJ61395.1    
 BcellWH2_00900   Bacteroides cellulosilyticus WH2 ALJ58162.1    
 BcellWH2_02119   Bacteroides cellulosilyticus WH2 ALJ59362.1    
 INE88_01250   Bacteroides eggerthii CL11T00C20 QUT44459.1    
 NQ546_00635   Bacteroides eggerthii DSM 20697 UWN88026.1    
 I6J51_04850   Bacteroides eggerthii FDAARGOS_1221 QRQ49631.1    
 K6V30_09825   Bacteroides faecis BFG-108 UBE47069.1    
 K6V30_09780   Bacteroides faecis BFG-108 UBE47060.1    
 NXX87_11135   Bacteroides faecis BFG-467 UVS36566.1    
 NXX87_11455   Bacteroides faecis BFG-467 UVS36630.1    
 NXW99_10710   Bacteroides faecis BFG-513 UVS50658.1    
 NXW99_10750   Bacteroides faecis BFG-513 UVS50666.1    
 NXY30_11145   Bacteroides faecis BFG-527 UVQ76877.1    
 NXW26_11175   Bacteroides faecis BFG-554 UVR67272.1    
 NXW58_11735   Bacteroides faecis BFG-624 UVP35434.1    
 KQP61_23290   Bacteroides faecis WAL8736 UYU57038.1    
 KQP61_23245   Bacteroides faecis WAL8736 UYU57029.1    
 BacF7301_11015   Bacteroides faecium CBA7301 QIU97481.1    
 BacF7301_01940   Bacteroides faecium CBA7301 QIU92981.1    
 BacF7301_10960   Bacteroides faecium CBA7301 QIU97480.1    
 BacF7301_11065   Bacteroides faecium CBA7301 QIU94646.1    
 BF638R_0912   Bacteroides fragilis 638R CBW21482.1    
 BF638R_0934   Bacteroides fragilis 638R CBW21502.1    
 NC657_15350   Bacteroides fragilis 86-5443-2-2 USA56429.1    
 NC657_15445   Bacteroides fragilis 86-5443-2-2 USA56448.1    
 α-N-acetylgalactosaminidase (NagA)   Bacteroides fragilis ATCC25285D CAJ01378.1    
 α-N-acetylgalactosaminidase   Bacteroides fragilis ATCC25285D CAJ01379.1    
 MB0529_00846   Bacteroides fragilis BE1 CUA17502.1    
 MB0529_00865   Bacteroides fragilis BE1 CUA17521.1    
 K6V22_03650   Bacteroides fragilis BFG-1 UBF17609.1    
 K6V22_03750   Bacteroides fragilis BFG-1 UBF17629.1    
 NXW51_08290   Bacteroides fragilis BFG-13 UVQ04062.1    
 NXW51_08390   Bacteroides fragilis BFG-13 UVQ04081.1    
 NXV04_07880   Bacteroides fragilis BFG-14 UVP08427.1    
 NXV04_07975   Bacteroides fragilis BFG-14 UVP08446.1    
 NXX28_07625   Bacteroides fragilis BFG-16 UVO83570.1    
 NXX28_07525   Bacteroides fragilis BFG-16 UVO83550.1    
 NXW03_08230   Bacteroides fragilis BFG-167 UVQ85510.1    
 NXW03_08330   Bacteroides fragilis BFG-167 UVQ85529.1    
 NXV54_07840   Bacteroides fragilis BFG-17 UVP87227.1    
 NXV54_07940   Bacteroides fragilis BFG-17 UVP87245.1    
 NXY24_07925   Bacteroides fragilis BFG-18 UVP17255.1    
 NXY24_07830   Bacteroides fragilis BFG-18 UVP17238.1    
 NXY03_07780   Bacteroides fragilis BFG-23 UVQ57020.1    
 NXY03_07680   Bacteroides fragilis BFG-23 UVQ57000.1    
 NXW55_08145   Bacteroides fragilis BFG-300 UVS01480.1    
 NXW55_08240   Bacteroides fragilis BFG-300 UVS01495.1    
 NXW06_07395   Bacteroides fragilis BFG-310 UVP95466.1    
 NXW06_07490   Bacteroides fragilis BFG-310 UVP95482.1    
 NXX17_08050   Bacteroides fragilis BFG-317 UVR19620.1    
 NXX17_08150   Bacteroides fragilis BFG-317 UVR19639.1    
 NXW10_08700   Bacteroides fragilis BFG-403 UVO62765.1    
 NXW10_08805   Bacteroides fragilis BFG-403 UVO62786.1    
 NXV32_07985   Bacteroides fragilis BFG-435 UVO87300.1    
 NXV32_08095   Bacteroides fragilis BFG-435 UVO87315.1    
 NXV34_08340   Bacteroides fragilis BFG-448 UVP91514.1    
 NXV34_08435   Bacteroides fragilis BFG-448 UVP91531.1    
 NXW84_13070   Bacteroides fragilis BFG-450 UVV75504.1    
 NXX41_07400   Bacteroides fragilis BFG-480 UVP47939.1    
 NXX41_07290   Bacteroides fragilis BFG-480 UVP47917.1    
 NXY37_08380   Bacteroides fragilis BFG-481 UVQ89749.1    
 NXY37_08480   Bacteroides fragilis BFG-481 UVQ89768.1    
 NXW39_07680   Bacteroides fragilis BFG-49 UVO91440.1    
 NXW39_07565   Bacteroides fragilis BFG-49 UVO91417.1    
 NXY01_07955   Bacteroides fragilis BFG-492 UVV63690.1    
 NXY01_08050   Bacteroides fragilis BFG-492 UVV63700.1    
 NXX63_08125   Bacteroides fragilis BFG-502 UVR71609.1    
 NXX63_08210   Bacteroides fragilis BFG-502 UVR71626.1    
 NXV19_07765   Bacteroides fragilis BFG-504 UVQ16546.1    
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