| Mechanism | Retaining a |
|---|---|
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Unclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786) |
| Catalytic Proton Donor | Glu (experimental) |
| Note | Created after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363 |
| External resources | CAZypedia; |
| Statistics | GenBank accession (726); Uniprot accession (8); PDB accession (40); 3D entries (3); cryst (0) |
| Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
| H104 | 3.2.1.130 | mannosyl-oligosaccharide endo-a-1,2-mannosidase | [aDGlcp | 1,3 | aDManp | 1,2 | aDManp | 1,2 | aDManp | H2O |
| H153 | 3.2.1.198 | N-glycan endo-a-1,2-mannosidase | [aDManp | 1,3 | aDManp | 1,2 | aDManp | 1,2 | aDManp | H2O |
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