Mechanism	Retaining a
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Unclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton Donor	Glu (experimental)
Note	Created after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resources	CAZypedia;
Statistics	GenBank accession (683); Uniprot accession (8); PDB accession (40); 3D entries (3); cryst (0)

Activity Id	EC#	Activity Name	Residue -2	Bond -1	Residue -1	Reacting Bond	Residue +1	Bond +1	Residue +2	Reactant
H104	3.2.1.130	mannosyl-oligosaccharide endo-a-1,2-mannosidase	[aDGlcp	1,3	aDManp	1,2	aDManp	1,2	aDManp	H2O
H153	3.2.1.198	N-glycan endo-a-1,2-mannosidase	[aDManp	1,3	aDManp	1,2	aDManp	1,2	aDManp	H2O
Top