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Glycoside Hydrolase Family 42

Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteIdentification of the catalytic residues in doi:10.1016/j.febslet.2007.04.053
External resourcesCAZypedia;
Statistics GenBank accession (12335); Uniprot accession (82); PDB accession (21); 3D entries (12); cryst (1)
Summary
Download GH42 (12304) Taxonomic display Structure (12 - 1 cryst) Characterized (79) Activities in Family (3)
Archaea
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-galactosidase (BgaH) 3.2.1.23 pubmed
 Haloferax volcanii SB1 AAB40123.2 P94804  
 β-galactosidase (Bga; Hlac_2868) 3.2.1.23 pubmed
 Halorubrum lacusprofundi ATCC 49239 ACM58428.1 B9LW38 6LVW[A]
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-galactosidase (GalB;LacB;Bgly;Aaci_2891) 3.2.1.23 pubmed
 Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 ACV59895.1
AAZ81841.1
ABI84370.1		 C8WV58
Q06GJ1
Q0R5R5		  
 β-galactosidase 3.2.1.23 pubmed
 Alicyclobacillus vulcanalis DSM16176 WP_076345996.1    
 β-galactosidase 3.2.1.23 pubmed
 Arthrobacter sp. 32c ACU00913.1 C7ASJ5  
 β-galactosidase 12 (LacG) (possible fragment) 3.2.1.23 pubmed
 Arthrobacter sp. B7 AAA75601.1 Q44233  
 β-galactosidase (GalB) 3.2.1.23 pubmed
 Arthrobacter sp. ON14 ADJ18282.1 D9IU57  
 β-galactosidase (LacA;BLi04277;BL00264) 3.2.1.23 pubmed
 Bacillus licheniformis DSM 13 = ATCC 14580 AAU43090.1
AAU25712.1
ACP63807.1		 Q65CX4  
 β-galactosidase (BglZQ) 3.2.1.23 pubmed
 Bacillus licheniformis ZQ1-8 AHW49175.1 X5D2S6  
 β-galactosidase, partial (Gal42) 3.2.1.23 pubmed
 Bacillus sp. (in: firmicutes) BY02 QSJ03389.1    
 β-galactosidase (LacA) 3.2.1.23 URL
 Bacillus subtilis G1 ACB72733.1 B2LUM2  
 β-galactosidase (YesZ; BSU07080) 3.2.1.23 pubmed
 Bacillus subtilis subsp. subtilis str. 168 CAB12527.1
AIY91999.1
AQR80664.1
AQR84877.1
NP_388589.1		 A0A6M3Z8Q4
O31529		  
 β-galactosidase (GanA; LacA; YvfN; BSU34130) 3.2.1.23 pubmed
 Bacillus subtilis subsp. subtilis str. 168 CAB15418.1
AIY94732.1
AQR83448.1
AQR87663.1
CAB08008.1
NP_391293.1		 O07012  
 β-galactosidase (BgaB; BgalII) 3.2.1.23 pubmed
 Bifidobacterium adolescentis DSM 20083 AAR24113.1 A1A399
Q5J883		 5VYM[A,B]
 β-galactosidase (Bg42-106) 3.2.1.23 pubmed
 Bifidobacterium animalis B106 AGH68883.1 S4U4B5  
 β-1,6/β-1,3-galactosidase (BlGal42A;Balac_0484) (Gal42A) 3.2.1.23 pubmed
 Bifidobacterium animalis subsp. lactis Bl-04 ACS45863.1 C6A6W5 4UNI[A,B,C]
4UOQ[A,B,C]
4UOZ[A,B,C]
 α-L-arabinopyranosidase (BlArap42B; Balac_0053) 3.2.1.- pubmed
 Bifidobacterium animalis subsp. lactis Bl-04 ACS45449.1 A0A2H4A2Z3
C6A5Q1		 5XB7[A,B,C,D,E,F]
 β-galactosidase (BgaC; B216_08266; BBBF_1344) 3.2.1.23 pubmed
 Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98551.1
EKE50024.1		 A0AB33XKS2
K2I5J0		  
 β-galactosidase (B216_08730; BBJK_01679) 3.2.1.23 pubmed
 Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48156.1
EKE49942.1		 A0A286TCU8
A0AB33XKL5		  
 β-galactosidase P2 (BbgII) 3.2.1.23 pubmed
 Bifidobacterium bifidum NCIMB 41171 ABP87597.1 A5A2I5  
 β-galactosidase (BbgII;LacZ2;BBIF_1313) 3.2.1.23 pubmed
 Bifidobacterium bifidum S17 ADO53518.1 E3EPA1 4UCF[A,B,C]
4UZS[A,B,C]
 β-galactosidase (Bgal; GalA; LacA) 3.2.1.23 pubmed
 Bifidobacterium breve ATCC 15698 / B24 AAU00556.1 Q68GW3  
 β-galactosidase (GalG; Lacz4; Bbr_0420_galG; Bbr_0420) 3.2.1.23 pubmed
 Bifidobacterium breve UCC2003 ABE95118.1
ADO51667.1		 F9Y1U6  
 β-galactosidase (GosG; Lacz5; LntA; BgaB; Bbr_0529_gosG; Bbr_0529) 3.2.1.23 pubmed
 Bifidobacterium breve UCC2003 ABE95226.1    
 β-1,4-galactosidase (Bbry_0422) 3.2.1.23 pubmed
 Bifidobacterium breve Yakult BAR71185.1 A0A0F7QXK8  
 β-1,3-galactosidase (Bdg42A) 3.2.1.- pubmed
 Bifidobacterium dentium Y510 UGN49369.1    
 β-galactosidase (BLGLB1; BgaB) 3.2.1.23 pubmed
 Bifidobacterium longum 020402 WP_032737298.1    
 β-galactosidase (LacA1;BLD_0926) 3.2.1.23 URL
 Bifidobacterium longum DJO10A ACD98372.1 B3DTA3  
 β-galactosidase 42A (BiBga42A; BgaG; Blon_2016) (agarotriose-active) (Bga42A) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53083.1
WP_012578289.1		 B7GUD7
Q93GI5		 8IBR[A]
8IBS[A,B,C,D,E,F]
8IBT[A,B]
 β-galactosidase 42B (Blon_2123) (Bga42B) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53184.1
WP_012578388.1		 B7GUN8  
 β-galactosidase 42C (Blon_2416) (Bga42C) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53470.1
WP_012578637.1		 B7GNW4  
 β-galactosidase (INF1) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. infantis DSM20088 CAC14567.1 Q9F4C8  
 β-galactosidase III (β-GalIII) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. infantis HL96 AAL02053.1 Q93GI5  
 β-galactosidase (BgaD; B8809_0415) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. longum NCIMB8809 ALO72088.1    
 β-galactosidase (B8809_0321) 3.2.1.23 pubmed
 Bifidobacterium longum subsp. longum NCIMB8809 ALO71994.1    
 β-galactosidase (BPGLB1) 3.2.1.23 pubmed
 Bifidobacterium pseudocatenulatum 070108 WP_117656455.1    
 β-galactosidase (Csac_1018) 3.2.1.23 pubmed
 Caldicellulosiruptor saccharolyticus DSM 8903 ABP66632.1 A4XI97  
 β-galactosidase (BgaB) 3.2.1.23 pubmed
 Carnobacterium maltaromaticum AAF16519.1 Q9RFN0  
 β-galactosidase / α-L-arabinopyranosidase (BgaA) 3.2.1.23
3.2.1.-		 pubmed
pubmed
 Clostridium cellulovorans AAN05452.1 D9SM34
Q8GEE3		  
 β-galactosidase (Pbg) 3.2.1.23 pubmed
 Clostridium perfringens BAA08485.1
CAA66274.1		 Q0TUR6
Q59312
Q79A09		  
 β-galactosidase (Dgeo_2829) 3.2.1.23 pubmed
 Deinococcus geothermalis DSM 11300 ABF44258.1
YP_594332.1		 Q1J2M6  
 β-galactosidase / exo-β-1,4-galactanase (GanB;LacB;Dda3937_02393) 3.2.1.23 pubmed
 Dickeya dadantii 3937 ADM99399.1 E0SM64  
 β-galactosidase (Dtur_0505) 3.2.1.23 pubmed
 Dictyoglomus turgidum DSM 6724 ACK41798.1 B8E215  
 β-galactosidase (Gal; GYB58_00550) 3.2.1.23 pubmed
 Gammaproteobacteria bacterium MBR9790212.1    
 β-galactosidase I (BgaB) 3.2.1.23 pubmed
 Geobacillus stearothermophilus KVE39 AAA22262.1 P19668  
 β-galactosidase 42B (GanB; Gan42B) (intracellular) 3.2.1.23 pubmed
 Geobacillus stearothermophilus T-6 AEH26455.1 F8TRX0 4OIF[A,B,C]
4OJY[A,B,C]
5DFA[A,B,C]
 β-galactosidase (Gal308) (thermostable) 3.2.1.23 pubmed
 Geobacillus thermocatenulatus KNOUC105 AAW56416.1 Q5I201  
 β-galactosidase (LacZ) 3.2.1.23 pubmed
 Heyndrickxia coagulans DSM 1 ADF47156.1 D5JGG0  
 β-galactosidase (BcGalB; E2E33_010705) 3.2.1.23 pubmed
 Heyndrickxia coagulans MA-13 MBF8418755.1
WP_133536219.1		    
 β-galactosidase (BcBga) 3.2.1.23 pubmed
 Heyndrickxia coagulans NL01 AKB91764.1 A0A1L1XWG1  
 thermostable galactosidase (Act) 3.2.1.23 doi
 Heyndrickxia coagulans T242 AFC88037.1 H9CTT9  
 β-galactosidase (GalC168) 3.2.1.23 pubmed
 Isoptericola sp. 168 ACV30341.1 C7T4Z3  
 β-galactosidase (BgaB) 3.2.1.23 pubmed
 Klebsiella pneumoniae 285 AEA30144.1 F2X2W6  
 β-galactosidase (LacA; Lp_3469) 3.2.1.23 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD65556.1
CCC80438.1
NP_786678.1		 F9UUD6  
 β-galactosidase (LacA) 3.2.1.23 pubmed
 Lactobacillus acidophilus FUA3191 CAZ66938.1 C6H178  
 β-galactosidase (LacZ;LBA1462) 3.2.1.23 pubmed
 Lactobacillus acidophilus NCFM ACC38288.1
AAV43283.1
CAN87410.1		 Q5FJ41
Q5FJ41		  
 β-galactosidase (bg42-164) 3.2.1.23 URL
 Lactobacillus sp. B164 AFC88544.1 H8Y676  
 β-galactosidase (MaBGA) 3.2.1.- pubmed
 Marinomonas sp. BSi20414 AKQ06240.1    
 β-galactosidase (M-bGal) 3.2.1.23 pubmed
 Marinomonas sp. ef1 WP_100635792.1 A0A6P3CWF7 6Y2K[A]
 β-galactosidase (Bcα-β-Gal) 3.2.1.23 pubmed
 Niallia circulans subsp. alkalophilus QCG73672.1 A0A4D6T0U7 3TTS[B,C,D,E,F]
3TTY[A,B,C,D,E,F]
3TTS[A]
 exo-β-1,3/4/6-galactanase / α-L-arabinopyranosidase (PpBGal42A) (Gal42A) 3.2.1.23
3.2.1.-		 pubmed
pubmed
 Paenibacillus polymyxa KF-1 WP_040101590.1 A0A3G8R2C6  
 β-galactosidase (BgaP1) 3.2.1.23 pubmed
 Paenibacillus sp. K1 ACE62913.1 B3VBH7  
 β-galactosidase (BgaP) 3.2.1.23 pubmed
 Planococcus sp. L4 ABI64125.1 Q09HN2 cryst
 β-galactosidase (BgaA) 3.2.1.23 pubmed
 Planococcus sp. SOS Orange AAF75984.1 Q9KI47  
 β-galactosidase (Achl_3125) 3.2.1.23 pubmed
 Pseudarthrobacter chlorophenolicus A6 ACL41086.1 B8HFB8  
 β-galactosidase (R-β-Gal) 3.2.1.23 pubmed
 Rahnella sp. R3 AJC52391.1 A0A0B4U8I5 5E9A[A,B,C,D,E,F]
 β-galactosidase 42A (Ccel_2451) (Gal42A) 3.2.1.23 pubmed
 Ruminiclostridium cellulolyticum H10 ACL76780.1 B8I615  
 β-galactosidase (BgalC;TM1195) 3.2.1.23 doi
 Thermotoga maritima MSB8 AAD36270.1
AAA50596.1
AGL50126.1
AHD18898.1
AKE28971.1
NP_229000.1		 Q56306
Q9X0S2
R4NSB2		  
 β-galactosidase (BgalB;TM0310) 3.2.1.23 doi
 Thermotoga maritima MSB8 AAD35398.1
AGL49234.1
AHD17926.1
AKE28111.1
NP_228122.1		 Q9WYE6
R4NXW2		  
 β-galactosidase (Tnap_1577) 3.2.1.23 doi
 Thermotoga petrophila RKU-10 ADA67652.1 D2C4J8  
 β-galactosidase (BgaA) 3.2.1.23 doi
 Thermus oshimai DSM 12092 ACV87364.1 C9EF70  
 β-galactosidase (A4-β-Gal) 3.2.1.23 pubmed
 Thermus sp. A4 BAA28362.1 O69315 1KWG[A]
1KWK[A]
 β-galactosidase (BgaA) 3.2.1.23 pubmed
 Thermus sp. IB-21 AAN05443.1 Q8GEA9  
 β-galactosidase (BgaA) 3.2.1.23 pubmed
 Thermus sp. T2 CAB07810.1 O54315  
 β-galactosidase 3.2.1.23 doi
 Thermus thermophilus KNOUC112 ABI35985.1 Q0GA06  
 β-galactosidase 3.2.1.23 doi
 Thermus thermophilus KNOUC114 ABI35983.1 Q0GA08  
 β-galactosidase (Zd410) 3.2.1.23 pubmed
 uncultured bacterium ADD69785.1 D4NYL2  
 β-galactosidase (Gal308) (thermostable) 3.2.1.23 pubmed
 uncultured bacterium AFD21844.1 H9BEW4  
 β-galactosidase (BgaP412) 3.2.1.23 pubmed
 uncultured bacterium AFD29748.1 H9BYJ8  
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