| Mechanism | Retaining e | 
|---|---|
| Clan | GH-A | 
| 3D Structure Status | ( β / α ) 8 barrel | 
| Catalytic Nucleophile/Base | Glu (experimental) | 
| Catalytic Proton Donor | Glu (experimental) | 
| Note | Identification of the catalytic residues in doi:10.1016/j.febslet.2007.04.053 | 
| External resources | CAZypedia; | 
| Statistics | GenBank accession (12335); Uniprot accession (82); PDB accession (21); 3D entries (12); cryst (1) | 
| Archaea | |||||||||||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | 
 | ||||||||||
| β-galactosidase (Bga; Hlac_2868) | 3.2.1.23 | Halorubrum lacusprofundi ATCC 49239 | ACM58428.1 | B9LW38 | 
 | ||||||||||
| Bacteria | |||||||||||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | 
 | ||||||||||
| β-galactosidase (BgaB; BgalII) | 3.2.1.23 | Bifidobacterium adolescentis DSM 20083 | AAR24113.1 | A1A399 Q5J883 | 
 | ||||||||||
| β-1,6/β-1,3-galactosidase (BlGal42A;Balac_0484) (Gal42A) | 3.2.1.23 | Bifidobacterium animalis subsp. lactis Bl-04 | ACS45863.1 | C6A6W5 | 
 | ||||||||||
| α-L-arabinopyranosidase (BlArap42B; Balac_0053) | 3.2.1.- | Bifidobacterium animalis subsp. lactis Bl-04 | ACS45449.1 | A0A2H4A2Z3 C6A5Q1 | 
 | ||||||||||
| β-galactosidase (BbgII;LacZ2;BBIF_1313) | 3.2.1.23 | Bifidobacterium bifidum S17 | ADO53518.1 | E3EPA1 | 
 | ||||||||||
| β-galactosidase 42A (BiBga42A; BgaG; Blon_2016) (agarotriose-active) (Bga42A) | 3.2.1.23 | Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 | ACJ53083.1 WP_012578289.1 | B7GUD7 Q93GI5 | 
 | ||||||||||
| β-galactosidase 42B (GanB; Gan42B) (intracellular) | 3.2.1.23 | Geobacillus stearothermophilus T-6 | AEH26455.1 | F8TRX0 | 
 | ||||||||||
| β-galactosidase (M-bGal) | 3.2.1.23 | Marinomonas sp. ef1 | WP_100635792.1 | A0A6P3CWF7 | 
 | ||||||||||
| β-galactosidase (Bcα-β-Gal) | 3.2.1.23 | Niallia circulans subsp. alkalophilus | QCG73672.1 | A0A4D6T0U7 | 
 | ||||||||||
| β-galactosidase (BgaP) | 3.2.1.23 | Planococcus sp. L4 | ABI64125.1 | Q09HN2 | 
 | ||||||||||
| β-galactosidase (R-β-Gal) | 3.2.1.23 | Rahnella sp. R3 | AJC52391.1 | A0A0B4U8I5 | 
 | ||||||||||
| β-galactosidase (A4-β-Gal) | 3.2.1.23 | Thermus sp. A4 | BAA28362.1 | O69315 | 
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