Mechanism	monooxygenase
Note	AA9 (formerly GH61). The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-b-D-glucanase activity in one family member. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name GH61, we recommend to describe these enzymes as "AA9 (formerly GH61)".
External resources	CAZypedia;
Statistics	GenBank accession (1418); Uniprot accession (49); PDB accession (108); 3D entries (24); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
lytic polysaccharide monooxygenase (CvAA9A)	1.14.99.54 1.14.99.56	Achaetomiella virescens CBS 547.75	AST24379.1	A0A223GEC9	5NLT[A,B,C,D,E,F] 1.90 6YDC[A,B,C,D] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.00 6YDD[A,B] β-D-Glcp-(1-4)-β-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.80 6YDE[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.20 6YDF[A,B] 2.12
NFIA_012990		Aspergillus fischeri NRRL 181	EAW22610.1		7OVA[A,B,C,D]
lytic cellulose monooxygenase (AfAA9_B; AFUA_4G07850; Afu4g07850)	1.14.99.54 1.14.99.56	Aspergillus fumigatus Af293	XP_752040.1 EAL90002.1	Q4WP32	5X6A[A,B] 1.70 6H1Z[A,B] 1.57 6HA5[A,B] 1.87 6HAQ[A,B] 1.37
AN6428.2		Aspergillus nidulans FGSC A4	EAA58450.1		8B7P[A,B,C,D]
lytic cellulose monooxygenase (CsLPMO9; CERSUDRAFT_85414)	1.14.99.54	Gelatoporia subvermispora B	EMD35432.1	M2RAI8	7EXK[A,B,C,D,E,F] 2.14
lytic cellulose monooxygenase (C1-hydroxylating) (HETIRDRAFT_166613; HiLPMO9B) (HiLPMO9B)	1.14.99.54	Heterobasidion irregulare TC 32-1	ETW87087.1	W4KMP1	5NNS[A,B] 2.10
lytic cellulose monooxygenase (C1-hydroxylating / C4-dehydrogenating) (LsAA9A)	1.14.99.54 1.14.99.56	Lentinus similis	ALN96977.1	A0A0S2GKZ1	5ACF[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.80 5ACG[A] 1.91 5ACH[A] 1.28 5ACI[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.75 5ACJ[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.70 5N04[A] 1.76 5N05[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.58 5NKW[A] β-D-Glcp-(1-4)-β-D-Manp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Manp-(1-4)-β-D-Glcp-(1-4)-β-D-Manp β-D-Glcp-(1-4)-β-D-Manp-(1-4)-β-D-Manp 1.48 5NLN[A] β-D-Xylp β-D-Xylp-(1-1)-<non_carb> 1.90 5NLO[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.33 5NLP[A] β-D-Xylp β-D-Xylp-(1-4)-α-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.59 5NLQ[A] β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-α-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.50 5NLR[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.00 5NLS[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.75 6YDG[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.90 7NIM[A] D-1,3,4-deoxy-Ribp 1.45 7NIN[A] D-1,3,4-deoxy-Ribp 1.40 7PQR[A] 1.30 7PTZ[A] 7PXI[A] 1.63 7PXJ[A] 1.75 7PXK[A] 1.40 7PXL[A] 1.35 7PXM[A] 1.30 7PXN[A] 1.65 7PXR[A] 1.80 7PXS[A] 1.90 7PXT[A] 2.40 7PXU[A] 1.80 7PXV[A] 1.50 7PXW[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.40 7PYD[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.21 7PYE[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.10 7PYF[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.90 7PYG[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.90 7PYH[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.90 7PYI[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.05 7PYL[A] 1.70 7PYM[A] 1.75 7PYN[A] 1.40 7PYO[A] 1.40 7PYP[A] 1.60 7PYQ[A] 1.60 7PYU[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.40 7PYW[A] β-D-Glcp-(1-4)-β-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.40 7PYX[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.60 7PYY[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.20 7PYZ[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.60 7PZ0[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.20 8S3F[A] 1.76 8S3L[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 2.60
ORF		Lentinus similis	QEM23792.1		6RS6[A] 1.60 6RS7[A] 1.60 6RS8[A] 1.58 6RS9[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.40
LPMO9F		Malbranchea cinnamomea FCH 10.5	QDV60870.1		7NTL[A] 1.38
Lytic cellulose monooxygenase (C4-dehydrogenating) (PMO-2;NcPMO-2;NcLPMO9D;GH61-4;NCU01050) (LPMO9D)	1.14.99.56	Neurospora crassa OR74A	CAD21296.1 EAA32426.1 XP_326543.1	Q1K8B6 Q8WZQ2	4EIR[A,B] 1.10 5TKF[A,B,C,D] 2.10 5TKG[A,B] 1.20 5TKH[A,B] 1.20 5TKI[A,B] 1.50 7T5C[A,B] 1.50 7T5D[A,B] 2.40 7T5E[A,B] 1.90
lytic cellulose monooxygenase (C1-hydroxylating) 9F (PMO-03328;LPMO-03328;NcLPMO9F;GH61-6;NCU03328) (LPMO9F)	1.14.99.54	Neurospora crassa OR74A	CAD70347.1 EAA26656.1 XP_322586.1	Q1K4Q1 Q873G1	4QI8[A,B] 1.10
lytic cellulose polysaccharide monooxygenase (C1-hydroxylating/C4-dehydrogenating) (PMO-3;NcLPMO9M;GH61-13;NcPMO-3;NCU07898) (LPMO9M)	1.14.99.54 1.14.99.56	Neurospora crassa OR74A	EAA33178.1 XP_328604.1	Q7SA19	4EIS[A,B] 1.37
Lytic cellulose monooxygenase (C4-dehydrogenating) (PMO-02916;LPMO-02916;NcLPMO9C;GH61-3;NCU02916) (LPMO9C)	1.14.99.56	Neurospora crassa OR74A	EAA36362.1 XP_330104.1	Q7SHI8	4D7U[A,B] 1.56 4D7V[A,B] 1.90
Lytic cellulose monooxygenase (C4-dehydrogenating) (GH61-1;NcLPMO9A;NCU02240)	1.14.99.56	Neurospora crassa OR74A	EAA30263.1 XP_331016.1	Q7S439	5FOH[A] 1.60
lytic cellulose monooxygenase (C1-hydroxylating) (Gh61D;PcGH61D;PcLPMO9D)	1.14.99.54	Phanerochaete chrysosporium K-3	BAL43430.1	H1AE14	4B5Q[A,B] 1.75
lytic polysaccharide monooxygenase (Lpmo1)		Talaromyces verruculosus PV2007	QBL14594.1		7A8V[A] α-D-Manp 1.95
lytic cellulose monooxygenase (C1-hydroxylating) (TaAA9; TaAA9A; TaGH61; TaGH61A;T aLPMO9A)	1.14.99.54	Thermoascus aurantiacus	ACS05720.1 ABW56451.1	G3XAP7	2YET[A,B] 1.50 3ZUD[A] 1.25 7PU1[A,B] 7PZ3[A] 1.90 7PZ4[A] 1.85 7PZ5[A] 1.45 7PZ6[A] 1.45 7PZ7[A] 1.80 7PZ8[A] 1.40 7Q1K[A] 1.36 8B4G[A]
lytic cellulose monooxygenase (C4-oxidizing) also active on xyloglucan (MtLPMO9J; MYCTH_79765) (MtLPMO9J)	1.14.99.56	Thermothelomyces thermophilus ATCC 42464	AEO56016.1	G2Q7A5	9BJQ[A,B] 1.80 9BJR[A,B] 2.20 9BJS[A,B] 2.00 9BJT[A,B] 3.00 9D0Z[A,B] 1.80
lytic cellulose monooxygenase (C4-dehydrogenating) (MYCTH_111088)	1.14.99.56	Thermothelomyces thermophilus ATCC 42464	AEO56416.1		9FDL[A,B,C] 2.33
lytic cellulose monooxygenase (C1-hydroxylating) (MtPMO3;MYCTH_92668)	1.14.99.54	Thermothelomyces thermophilus ATCC 42464	AEO56665.1	G2QAB5	5UFV[A,B,C,D,E,F] 2.45
lytic cellulose monooxygenase (C1-hydroxylating) (TtLPMO9E; TtAA9E; TtGH61E; THITE_2122979)	1.14.99.54	Thermothielavioides terrestris NRRL 8126	XP_003657366.1 ACE10234.1 AEO71030.1	D0VWZ9 G2RGE5	3EII[A,B,C,D] 2.25 3EJA[A,B,C,D] 1.90
lytic polysaccharide mono-oxygenase active on cellulose (EG7;HjGH61B) (Cel61B=GH61B)		Trichoderma reesei QM6A	AAP57753.1 ABH82048.1 ACK19226.1 ACR92640.1		2VTC[A,B] 1.6
lytic cellulose monooxygenase (C1-hydroxylating/C4-dehydrogenating) (EGIV; Egl4; EG4; TrLPMO) (formerly endo-β-1,4-glucanase IV) (LPMO9A)	1.14.99.54 1.14.99.56	Trichoderma reesei RUTC-30	CAA71999.1 EGR52697.1	G0R6T8 O14405	5O2W[A] 2.00 5O2X[A] 0.95
unclassified
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
ORF		compost metagenome			7VFC[A] 1.21
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