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Auxiliary Activity Family 3

Activities in FamilyPyranose:oxygen 2-oxidoreductase / glucose 2-oxidase (EC 1.1.3.10);
Alcohol oxidase (EC 1.1.3.13);
Ecdysone oxidase (EC 1.1.3.16);
Glucose 1-oxidase (EC 1.1.3.4);
Aryl alcohol oxidase (EC 1.1.3.7);
Oligosaccharide dehydrogenase (FAD) (EC 1.1.5.-);
Glucose 1-dehydrogenase (FAD, quinone) (EC 1.1.5.9);
Cellobiose dehydrogenase (EC 1.1.99.18);
Pyranose dehydrogenase (EC 1.1.99.29);
NoteAA3 enzymes belong to the glucose-methanol-choline (GMC) oxidoreductases family. AA3 enzymes are flavoproteins containing a flavin-adenine dinucleotide (FAD)-binding domain. Family AA3 can be divided into 4 subfamilies: AA3_1 (mostly cellobiose dehydrogenases), AA3_2 (including both aryl alcohol oxidase and glucose 1-oxidase), AA3_3 (alcohol oxidase) and AA3_4 (pyranose 2-oxidase).
External resourcesCAZypedia;
Statistics GenBank accession (4730); Uniprot accession (59); PDB accession (64); 3D entries (20); cryst (1)
Summary
Download AA3 (35464) Taxonomic display Structure (20 - 1 cryst) Characterized (54)
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D Subf
 pyranose dehydrogenase (PDH;AcPDH) 1.1.99.29 pubmed
 Agaricus campestris AHA85313.1 V5NDL4   2
 pyranose dehydrogenase (PDH;AxPDH) 1.1.99.29 pubmed
 Agaricus xanthodermus AHA85314.1 V5NC32   2
 glucose dehydrogenase (GDH,G4B84_001660) 1.1.5.9 pubmed
 Aspergillus flavus NRRL3357 QMW26415.1 A0A1S9DW10
B8MX95		 4YNT[A]
4YNU[A]
7VKD[A]
7VZP[A,B]
7VZS[A,B] 		2
 glucose oxidase (GgoX) 1.1.3.4   Aspergillus niger CAC12802.1 Q9HFQ1   2
 glucose oxidase (Gox1; AnGOx) 1.1.3.4 pubmed
 Aspergillus niger NRRL-3 AAA32695.1
AAB12628.1
AAQ78793.1
ACB30369.1
CAA34197.1
CAC27315.1
CAC83816.1		 B2CNX8
P13006
Q5Q041		 1CF3[A]
1GAL[A]
3QVP[A]
3QVR[A]
5NIT[A]
5NIW[A]
8JPZ[A,B] 		2
 alcohol oxidase (AOx) 1.1.3.13   Aspergillus terreus MTCC 6324 AFP17823.1 I7FDJ2   3
 glucose oxidase (ApGoxA; Aurpu2p4_000012; VTO58DRAFT_100515) 1.1.3.4 pubmed
 Aureobasidium pullulans ATCC 62921 KAL2034598.1     2
 glucose oxidase (AsGOxII; AUEXF2481DRAFT_9434) 1.1.3.4 pubmed
 Aureobasidium subglaciale EXF-2481 KEQ90431.1 A0A074YUB2   2
 alcohol oxidase (P68;Hv-p68) 1.1.3.13   Bipolaris victoriae ATTC 42018 AAK14990.1 Q9C1S3   3
 aryl alcohol oxidase (BaAAO) 1.1.3.7 pubmed
 Bjerkandera adusta     9AVH[A] 2
 ecdysone oxidase (BmEO;BGIBMGA005692) 1.1.3.16   Bombyx mori AEM17059.1 H6AGY0   2
 methanol oxidase (Aod1;AOD1) 1.1.3.13   Candida boidinii S2 / AOU-1 AAA34321.1 Q00922   3
 cellobiose dehydrogenase (CdhIIA; CaCDH IIA) 1.1.99.18 pubmed
 Chaetomium atrobrunneum CBS 238.71 ADT70773.1 E7D6C0   1
 glucose dehydrogenase (Gdh; GcGDH) 1.1.5.9 pubmed
 Colletotrichum gloeosporioides DSM 62728 AER13600.1 G8E4B5   2
 cellobiose dehydrogenase IIA (Cdh; MtCDH) 1.1.99.18   Crassicarpon hotsonii ABS45567.2
ABS45566.1		 A9XK87
A9XK88		 4QI4[A]
4QI5[A]
4QI6[A] 		1
 cellobiose dehydrogenase (CdhIIB; CaCDH IIA) 1.1.99.18 pubmed
 Crassicarpon thermophilum CBS 405.69 ADT70772.1 E7D6B9   1
 cellobiose dehydrogenase (CdhIIA; DsCDH IIA) 1.1.99.18 pubmed
 Dichomera saubinetii CBS 990.70 ADT70774.1 E7D6C1   1
 cellobiose dehydrogenase (Cdh) 1.1.99.18   Gelatoporia subvermispora FP-90031 ACF60617.1 B6D1P2   1
 alcohol oxidase (AoX) 1.1.3.13   Gloeophyllum trabeum ATCC 11539 / M617 ABI14440.1 A8DPS4   3
 cellobiose dehydrogenase (CdhIIB; HhCDH IIB) 1.1.99.18 pubmed
 Hypoxylon haematostroma CBS 255.63 ADT70776.1 E7D6C3   1
 oligosaccharide dehydrogenase (KiOdhA; jgi|Kocim1|624787; BD324DRAFT_624787) 1.1.5.- pubmed
 Kockovaella imperatae NRRL Y-17943 ORX37098.1 A0A1Y1UGF0   2
 alcohol oxidase / methanol oxidase (Aox1;AOX1;MOX1) 1.1.3.13   Komagataella pastoris NRRL Y-11430 AAB57849.1 F2QY27
P04842		 5HSA[A,B,C,D,E,F,G,H]
5I68[A] 		3
 alcohol oxidase (Aox2;AOX2) 1.1.3.13   Komagataella pastoris NRRL Y-11430 AAB57850.1 F2R038
P04842		   3
 pyranose 2-oxidase (P2Ox;LsP2O) 1.1.3.10   Lyophyllum shimeji BAD12079.1
Q75ZP8.1		 Q75ZP8   4
 pyranose dehydrogenase (Pdh1; PDH; AmPDH) 1.1.99.29 pubmed
 Macropsalliota meleagris AAW82996.1
AAW82997.1		 Q3L245 4H7U[A] 2
 glucose dehydrogenase (McGdhA; Malci1p7_002451; VTO42DRAFT_8318) 1.1.5.9 pubmed
 Malbranchea cinnamomea CBS 343.55 KAL1960358.1     2
 methanol oxidase (MOX;Mp-Mox) 1.1.3.13   Moniliophthora perniciosa AFO55203.1 I7CMK2   3
 glucose dehydrogenase (MpGDH) 1.1.5.9 pubmed
 Mucor circinelloides / Mucor prainii NISL0103 AGN09340.1     2
 oligosaccharide dehydrogenase (active on β-1,3 and β-1,6-gluco-oligosaccharides) (UmAA3_2A; UmGDHIII; UMAG_03551) 1.1.5.- pubmed
 Mycosarcoma maydis 521 KIS68464.1
XP_011389987.1		 A0A0D1DW37   2
 cellobiose dehydrogenase IIA (Cdh-1; CDH-1; CdhIIA; Nc-Cdh1; NcCDH IIA; NCU00206) 1.1.99.18 pubmed
 Neurospora crassa OR74A EAA27355.1
XP_322292.1		 Q7RXM0 4QI7[A,B] 1
 cellobiose dehydrogenase IIB (Cdh2; CdhIIB; CDH IIB; Nc-Cdh2; NCU05923) 1.1.99.18 pubmed
 Neurospora crassa OR74A EAA28998.1 Q7S0Y1   1
 alcohol oxidase / methanol oxidase (Mox1;MOX) 1.1.3.13   Ogataea angusta DL1 CAA26278.1
CAM84030.1
CAM84031.1
CAM84032.1		 A6PZG7
A6PZG8
A6PZG9
P04841		   3
 glucose oxidase 1.1.3.4   Penicillium amagasakiense   P81156 1GPE[A,B] 2
 glucose oxidase (GodP;GOD-w) 1.1.3.4   Penicillium chrysogenum F4 AFA42947.1 K9L4P7   2
 pyranose 2-oxidase / glucose 2-oxidase 1.1.3.10   Peniophora sp. SG AAO13382.1 Q8J136 1TZL[A,B,C,D,E,F,G,H]
2F5V[A]
2F6C[A] 		4
 pyranose 2-oxidase (PoX) 1.1.3.10   Phanerochaete chrysosporium BKM-F-1767 AAS93628.1
Q6QWR1.1		 Q6QWR1 4MIF[A,B,C,D]
4MIG[A,B,C,D]
4MIH[A,B,C,D,E,F,G,H] 		4
 alcohol oxidase (Aox1) 1.1.3.13   Phanerochaete chrysosporium DSMZ 1547 CDG66232.1 A0A977TIR6
T2M2J4		 6H3G[A,B,C,D,E,F,G,H]
6H3O[A,B,C,D,E,F,G,H]
8IL5[A,B] 		3
 cellobiose dehydrogenase I (CdH) 1.1.99.18   Phanerochaete chrysosporium K3 CAA61359.1
AAB92262.1		 Q01738
Q12661		   1
 aryl-alcohol oxidase (AaO; PeAAOX; PeAOO) 1.1.3.7 pubmed
 Pleurotus eryngii ATCC90787; CBS 613.91; IJFM A169 AAC72747.1 O94219 3FIM[B]
5OC1[A] 		2
 aryl-alcohol oxidase (AaO; PpAAox) 1.1.3.7   Pleurotus pulmonarius CBS 507.85 AAF31169.1 Q9P928 cryst 2
 FAD-dependent glucose dehydrogenase (FadgdH; FAD-GDH) 1.1.5.9 pubmed
 Rasamsonia emersonii NBRC 31232 BAV89805.1 A0A1E1GL61   2
 oligosaccharide dehydrogenase (RsGDHIII; RSOLAG1IB_10481) 1.1.5.- pubmed
 Rhizoctonia solani AG-1 IB CEL62789.1 A0A0B7G104   2
 cellobiose dehydrogenase (CdhIIA2; SbCDH IIA2) 1.1.99.18 pubmed
 Stachybotrys bisbyi DSM 630.42 ADT70778.1 E7D6C5   1
 glucose oxidase (TaGdhA; Theau2p4_003545; VTN00DRAFT_4631) 1.1.5.9 pubmed
 Thermoascus crustaceus CBS 181.67 KAL2011913.1     2
 FAD-dependent glucose dehydrogenase (FadgdH; FAD-GDH) 1.1.5.9 pubmed
 Thermoascus crustaceus NBRC 9129 BAV89806.1 A0A1E1GL87   2
 cellobiose dehydrogenase (Cdh;MYCTH_111388) 1.1.99.18   Thermothelomyces thermophilus ATCC 42464 AEO58137.1
AAC26221.1		 O74240   1
 cellobiose dehydrogenase (CDH-2;MtCDH-2;MYCTH_81925) 1.1.99.18   Thermothelomyces thermophilus ATCC 42464 AEO59298.1 G2QFY4   1
 cellobiose dehydrogenase (CbdA,THITE_59724) 1.1.99.18 pubmed
 Thermothielavioides terrestris NRRL 8126 AEO69014.1 G2RB43   1
 oligosaccharide dehydrogenase (active on β-1,3 and β-1,3-1,4-gluco-oligosaccharides) (ODH; BN946_scf184803.g17) 1.1.5.- pubmed
 Trametes cinnabarina BRFM137 CDO69819.1 A0A060SC37 6XUT[A]
6XUU[A]
6XUV[A]
8RIC[A,B]
8RID[A]
8RIE[A] 		2
 cellobiose dehydrogenase 1.1.99.18   Trametes cinnabarina ss3 / BRFM 137 ADX41688.1 F1DFN2   1
 pyranose 2-oxidase (P2O;TmP2O) 1.1.3.10   Trametes ochracea MB49 AAP40332.1 Q7ZA32 4MOE[A,B,C,D]
4MOF[A]
4MOG[A]
4MOH[A]
4MOI[A,B]
4MOJ[A,B,C,D]
4MOK[A,B,C,D]
4MOL[A,B,C,D]
4MOM[A,B,C,D]
4MOO[A]
4MOP[A,B,C,D]
4MOQ[A,B]
4MOR[A,B,C,D]
4MOS[A] 		4
 pyranose oxidase (P2O) 1.1.3.10   Trametes pubescens CBS 696.94 AAW57304.1 Q5G234   4
 glucose dehydrogenase (TvGDHII; TrVGV298_012057) 1.1.5.9 pubmed
 Trichoderma virens Gv29-8 UKZ58190.1
EHK19553.1		 G9N1C2   2
 aryl-alcohol oxidase (UmaAAO; UM04044; UMAG_04044) 1.1.3.7   Ustilago maydis 521 KIS68002.1 A0A0D1C2K9   2
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