GlycosylTransferase Family 49

Activities in Familyβ-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.-).
Mechanism Inverting
3D Structure StatusGT-A (AlphaFold)
NoteThe animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesCFG(Glycosphingolipid); CFG(N-linked); CFG(Terminal); Glymap;
Statistics GenBank accession (501); Uniprot accession (14); PDB accession (3); 3D entries (1); cryst (0)

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