GlycosylTransferase Family 47

Activities in FamilyGlucomannan β-1,2-galactosyltransferase (EC 2.4.1.-);
Pectin β-1,4-glucuronyltransferase (EC 2.4.1.-);
Xyloglucan β-1,2-galactosyltransferase (EC 2.4.1.-);
Xyloglucan β-1,2-galacturonyltransferase (EC 2.4.1.-);
UDP-GlcA: N-acetylglucosaminyl-proteoglycan β-1,4-glucuronosyltransferase (EC 2.4.1.225);
UDP-Xyl: xylan β-1,4-xylosyltransferase (EC 2.4.2.-);
α-1,3-L-arabinofuranosyltransferase (EC 2.4.2.-);
Arabinan α-1,5-L-arabinofuranosyltransferase (EC 2.4.2.-);
Xylogalacturonan β-1,3-xylosyltransferase (EC 2.4.2.41);
Mechanism Inverting
3D Structure StatusGT-B
NoteThe long animal heparan synthases are made of two domains. The N-terminal domain, which adds b-1,4-GlcA residues, belongs to family GT47 while the C-terminal domain, which adds a-1,4-GlcNAc residues, belongs to family GT64. The plant homologs, which have a single domain, display various specificities ranging from xyloglucan b-galactosyltransferase to a pectin b-glucuronyltransferase and arabinan a-L-arabinosyltransferase.
External resourcesGlymap;
Statistics GenBank accession (2924); Uniprot accession (43); PDB accession (16); 3D entries (3); cryst (0)


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