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GlycosylTransferase Family 42

Activities in FamilyCMP-Neu5Ac: α-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.3.3);
CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (EC 2.4.3.4);
CMP-Neu5Ac: N-acetyllactoside α-2,3-sialyltransferase (EC 2.4.3.6);
CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase (EC 2.4.3.8);
Mechanism Inverting
NoteThese enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resourcesCAZypedia;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (502); Uniprot accession (15); PDB accession (9); 3D entries (2); cryst (0)
Summary
Download GT42 (470) Taxonomic display Structure (2) Characterized (15)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CstII   Campylobacter jejuni GC057 ABD94158.1    
 CstII   Campylobacter jejuni GC124 ABG00193.1    
 α-2,3 sialyltransferase (Cst-II)   Campylobacter jejuni GC158 AHI17065.1    
 α-2,3-sialyltransferase (cst-II)   Campylobacter jejuni GC175 AAZ04362.1    
 AD53_06495   Campylobacter jejuni HF5-4A-4 APU78015.1    
 Cst-II   Campylobacter jejuni LXC ABI32318.1    
 Cst-II   Campylobacter jejuni MF20 ABM74196.1    
 ORF   Campylobacter jejuni MF6 AAR82857.1    
 α-2,3/-2,8-sialyltransferase (cst-II)   Campylobacter jejuni MF7 ABA29484.1    
 α-2,3-sialyltransferase (Cst-II) 2.4.3.4 Campylobacter jejuni MF8 AAZ80462.1 Q93D05  
 α-2,3-sialyltransferase cstIII   Campylobacter jejuni MSC57360 AAG29922.1 Q7BP25  
 CJ12660_1136 (CstI)   Campylobacter jejuni NCTC 12660 AWB39060.1    
 CJ12664_1081 (CstI)   Campylobacter jejuni NCTC 12664 AWB42241.1    
 ERS445056_01564   Campylobacter jejuni NCTC11351 CKH01460.1    
 ERS445056_01250   Campylobacter jejuni NCTC11351 CKG92251.1    
 NCTC13255_01171   Campylobacter jejuni NCTC13255 VEI84977.1    
 NCTC13255_01449   Campylobacter jejuni NCTC13255 VEI85249.1    
 NCTC13261_01194   Campylobacter jejuni NCTC13261 VEI87016.1    
 NCTC13266_01165   Campylobacter jejuni NCTC13266 VEI79482.1    
 NCTC13268_01310   Campylobacter jejuni NCTC13268 VEI83246.1    
 BD30_05670   Campylobacter jejuni NS4-1-1 APU82977.1    
 BD32_05670   Campylobacter jejuni NS4-5-1 APU84636.1    
 BD33_05670   Campylobacter jejuni NS4-9-1 APU86302.1    
 α-2,3/α-2,8-sialyltransferase II (cstII)   Campylobacter jejuni O:10 CAF04167.1
AAO96669.1
ACK29126.1
CAK26616.1		    
 α-2,3/α-2,8-sialyltransferase II (CstII;Cst)   Campylobacter jejuni O:19 CAF04169.1
AAO96671.1
ACK29128.1
CAK26618.1		    
 α-2,3/α-2,8-sialyltransferase II (CstII)   Campylobacter jejuni O:36 CAF04171.1    
 α-2,3/α-2,8-sialyltransferase II (CstII)   Campylobacter jejuni O:4 CAF04170.1    
 α-2,3/α-2,8-sialyltransferase II (CstII)   Campylobacter jejuni O:41 CAF04168.1
AAO96670.1
AAT17967.1
AAU96097.1
AAW18140.1
ACK29127.1
CAK26617.1		    
 A0W68_05930   Campylobacter jejuni OD267 AMP65449.1    
 α-2,3-sialyltransferase (Cst-I) 2.4.3.4 Campylobacter jejuni OH4384 AAF13495.1
AAS36261.1
AAT23232.1		 Q9RGF1 2P2V[A]
2P56[A]
 bifunctional CMP-Neu5Ac: α-2,3/-2,8-sialyltransferase (CstII;Cst-II) 2.4.3.4
2.4.3.8		 Campylobacter jejuni OH4384 AAF31771.1
AAO96668.1
AAT17965.1
ABA06995.1
ABA09514.1
ABH12650.1
ABI05854.1
ACK29125.1
CAF04166.1
CAK26615.1		 Q9LAK3 1RO7[A,B,C,D]
1RO8[A,B]
2DRJ[A]
2WQQ[A]
2X61[A,B]
2X62[A,B]
2X63[A]
 Cst-II (fragment)   Campylobacter jejuni QYT ABI32331.1    
 AOD58_05640   Campylobacter jejuni RM1285 ALJ17818.1    
 CstII   Campylobacter jejuni RM1503 ABN43105.1    
 AXW77_05605   Campylobacter jejuni RM3194 AMK27985.1    
 PJ16_05940   Campylobacter jejuni subsp. jejuni 00-0949 AJK84948.1    
 PJ17_05835   Campylobacter jejuni subsp. jejuni 00-1597 AJK71280.1    
 N135_01177 (CstIII)   Campylobacter jejuni subsp. jejuni 00-2425 AGV56910.1    
 N564_01106 (CstIII)   Campylobacter jejuni subsp. jejuni 00-2426 AGV51422.1    
 N565_01149 (CstIII)   Campylobacter jejuni subsp. jejuni 00-2538 AGV49744.1    
 N755_01144 (CstIII)   Campylobacter jejuni subsp. jejuni 00-2544 AGV47983.1    
 PJ18_05650   Campylobacter jejuni subsp. jejuni 00-6200 AJK72968.1    
 PJ19_06205   Campylobacter jejuni subsp. jejuni 01-1512 AJK83113.1    
 CJ14980A_1142 (CstI)   Campylobacter jejuni subsp. jejuni 14980A AOH52165.1    
 Cj81-011   Campylobacter jejuni subsp. jejuni 81-176 AAW56104.1    
 multi-functionnal CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase and CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (CJJ81176_1157) 2.4.3.4
2.4.3.8		 Campylobacter jejuni subsp. jejuni 81-176 EAQ72171.1
AAL09368.1		 A0A0H3P9T9
A1W0C6
Q9L9Q5		  
 B1780_05760   Campylobacter jejuni subsp. jejuni ATCC 33560 AZU51181.1    
 α-2,3-sialyltransferase (CstL)   Campylobacter jejuni subsp. jejuni ATCC 43446 AAX33819.1    
 CJD42_5385   Campylobacter jejuni subsp. jejuni D42a APA81385.1    
 A6J90_08700   Campylobacter jejuni subsp. jejuni FDAARGOS_262 ASE87127.1    
 A6J90_07150   Campylobacter jejuni subsp. jejuni FDAARGOS_262 ASE86838.1    
 A6J91_02430   Campylobacter jejuni subsp. jejuni FDAARGOS_263 ASE87710.1    
 A6J93_05875   Campylobacter jejuni subsp. jejuni FDAARGOS_265 ASE89959.1    
 α-2,3-/2,8-sialyltransferase   Campylobacter jejuni subsp. jejuni GC149 AAY27725.1    
 A17_01193   Campylobacter jejuni subsp. jejuni huA17 AZR09046.1    
 CJSA_1082 (CstIII)   Campylobacter jejuni subsp. jejuni IA3902 ADC28720.1    
 ICDCCJ07001_1098   Campylobacter jejuni subsp. jejuni ICDCCJ07001 ADT66430.1    
 CJM129_5735   Campylobacter jejuni subsp. jejuni M129 APA79632.1    
 MTVDSCj07_1085 (CstIII)   Campylobacter jejuni subsp. jejuni MTVDSCj07 AON65696.1    
 MTVDSCj13_1138 (CstII)   Campylobacter jejuni subsp. jejuni MTVDSCj13 AON67302.1    
 MTVDSCj16_1290 (CstII)   Campylobacter jejuni subsp. jejuni MTVDSCj16 AON69053.1    
 F1716_06945   Campylobacter jejuni subsp. jejuni NADC 20827 QFZ66276.1    
 α-2,3-sialyltransferase (CstIII;Cj1140)   Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 CAB73395.1
CAL35257.1
NP_282288.1		 Q0P9B4  
 BN148_1140 (CstIII)   Campylobacter jejuni subsp. jejuni NCTC 11168-BN148 CCK67234.1    
 N920_05705   Campylobacter jejuni subsp. jejuni NCTC 11168-GSv AHK59595.1    
 N916_05690   Campylobacter jejuni subsp. jejuni NCTC 11168-K12E5 AHK52932.1    
 N919_05695   Campylobacter jejuni subsp. jejuni NCTC 11168-Kf1 AHK54598.1    
 N917_05685   Campylobacter jejuni subsp. jejuni NCTC 11168-mcK12E5 AHK56262.1    
 N918_05680   Campylobacter jejuni subsp. jejuni NCTC 11168-mfK12E5 AHK57926.1    
 NCTC10983_01136 (CstIII)   Campylobacter jejuni subsp. jejuni NCTC10983 VEJ11311.1    
 NCTC11168_01133 (CstIII)   Campylobacter jejuni subsp. jejuni NCTC11168 SQF80123.1    
 NCTC12109_01135   Campylobacter jejuni subsp. jejuni NCTC12109 VEJ01140.1    
 A911_05525   Campylobacter jejuni subsp. jejuni PT14 AFU43192.1    
 CjjRM1285_1156 (CstII)   Campylobacter jejuni subsp. jejuni RM1285 ANS24222.1    
 CjjRM1285_1436 (CstI)   Campylobacter jejuni subsp. jejuni RM1285 ANS24493.1    
 CjjRM3196_1156 (CstII)   Campylobacter jejuni subsp. jejuni RM3196 ALF93807.1    
 CjjRM3197_1156 (CstII)   Campylobacter jejuni subsp. jejuni RM3197 ALF92171.1    
 HS33.28   Campylobacter jejuni subsp. jejuni RM4271 ALN44118.1    
 CjjRM3420_1095 (CstII)   Campylobacter jejuni subsp. jejuni str. RM3420 AOW97438.1    
 CjjRM3420_1434 (CstI)   Campylobacter jejuni subsp. jejuni str. RM3420 AOW97768.1    
 QZ67_01218 (fragment)   Campylobacter jejuni subsp. jejuni YH001 AJA55308.1    
 BLD42_06185   Campylobacter jejuni TS1218 APA47570.1    
 A0W69_06890   Campylobacter jejuni WP2202 AMP63857.1    
 B0D73_05965   Campylobacter jejuni YH002 ARJ53155.1    
 BLD41_06380   Campylobacter jejuni YQ2210 APB41565.1    
 Cst-II   Campylobacter jejuni ZB ABI32357.1    
 G3T45_05830   Campylobacter jejuni ZH003 QIW71986.1    
 G3T46_05825   Campylobacter jejuni ZH006 QIW70372.1    
 Cst-II   Campylobacter jejuni ZHX ABI32344.1    
 BLD40_06430   Campylobacter jejuni ZP3204 APB39798.1    
 G3T47_05795   Campylobacter jejuni ZS004 QIW68703.1    
 G3T47_07250   Campylobacter jejuni ZS004 QIW68978.1    
 G3T48_05505   Campylobacter jejuni ZS005 QIW67657.1    
 G3T49_02010   Campylobacter jejuni ZS006 QIW64801.1    
 CLLT_1242 (CstI)   Campylobacter lari subsp. lari LMG 8846 QKF75768.1    
 WJ046_06255   Campylobacter lari subsp. lari NCTC 11352 [WRI 3034/77] WYB90664.1    
 CMCT_1132 (CstI)   Campylobacter mucosalis ATCC 43264 QKF63256.1    
 CMUC_1594 (CstI)   Campylobacter mucosalis CCUG 21559 QCD45344.1    
 CNZW441b_1144   Campylobacter novaezeelandiae W441b QWU80451.1    
 CORN_1309 (CstI)   Campylobacter ornithocola LMG 29815 QKF57815.1    
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