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GlycosylTransferase Family 42

Activities in FamilyCMP-Neu5Ac: α-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.3.3);
CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (EC 2.4.3.4);
CMP-Neu5Ac: N-acetyllactoside α-2,3-sialyltransferase (EC 2.4.3.6);
CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase (EC 2.4.3.8);
Mechanism Inverting
NoteThese enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resourcesCAZypedia;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (501); Uniprot accession (15); PDB accession (9); 3D entries (2); cryst (0)
Summary
Download GT42 (469) Taxonomic display Structure (2) Characterized (15)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 HifGL_000071 (fragment)   Haemophilus influenzae KR494 AGV10908.1    
 INP89_08510   Haemophilus influenzae M1C112_1 QOR26446.1    
 INP89_05715   Haemophilus influenzae M1C112_1 QOR27489.1    
 DV389_03985   Haemophilus influenzae M21384 AXH82811.1    
 NCTC11394_00705   Haemophilus influenzae NCTC11394 VEB22703.1    
 NCTC11873_00712 (Lex1_2)   Haemophilus influenzae NCTC11873 VEI54555.1    
 NCTC11931_00638 (fragment)   Haemophilus influenzae NCTC11931 SQG35892.1    
 NCTC12194_00126   Haemophilus influenzae NCTC12194 SQJ00716.1    
 NCTC12194_00757   Haemophilus influenzae NCTC12194 SQJ01528.1    
 NCTC12699_00353 (Lex1_2)   Haemophilus influenzae NCTC12699 VEB27978.1    
 NCTC12975_00682 (fragment)   Haemophilus influenzae NCTC12975 SQH53501.1    
 NCTC12975_00126 (Lex1_1)   Haemophilus influenzae NCTC12975 SQH52984.1    
 NCTC13377_00699   Haemophilus influenzae NCTC13377 SQI74456.1    
 ERS450003_00723 (Lex1_3)   Haemophilus influenzae NCTC8143 CKG90188.1    
 ERS450003_00124 (Lex1_1)   Haemophilus influenzae NCTC8143 CKG73273.1    
 NCTC8455_00553 (Lex1)   Haemophilus influenzae NCTC8455 SQK92992.1    
 NCTC8468_00628   Haemophilus influenzae NCTC8468 VTP72076.1    
 BG256_03760   Haemophilus influenzae NML-Hia-1 AOZ66916.1    
 BG256_06490   Haemophilus influenzae NML-Hia-1 AOZ67410.1    
 NTHi2019_0431 (Lic3A)   Haemophilus influenzae NTHi2019 AGK63826.1    
 CMP-N-acetylneuraminate-β-galactosamide-α-2, 3-sialytransferase (SiaA2)   Haemophilus influenzae NTHi2019 AGK63827.1    
 CH556_00685   Haemophilus influenzae P595-8370 AXP57147.1    
 CH563_01245   Haemophilus influenzae P602-8883 AYO34293.1    
 CH576_03385   Haemophilus influenzae P615-8618 AXP66222.1    
 CH578_00620   Haemophilus influenzae P617-9224 AXP62308.1    
 CH578_03665   Haemophilus influenzae P617-9224 AXP62857.1    
 CH582_03385   Haemophilus influenzae P621-7028 AXP38725.1    
 CH597_03590   Haemophilus influenzae P636-8296 AXP60361.1    
 CH597_00620   Haemophilus influenzae P636-8296 AXP58828.1    
 CH602_00615   Haemophilus influenzae P641-4342 AXP75301.1    
 CH602_03415   Haemophilus influenzae P641-4342 AXP75800.1    
 CH603_00615   Haemophilus influenzae P642-4396 AXP53709.1    
 CH603_03760   Haemophilus influenzae P642-4396 AXP54277.1    
 CH611_00685   Haemophilus influenzae P650-8603 AXP40814.1    
 CH613_03375   Haemophilus influenzae P652-8881 AXP36035.1    
 CH613_00700   Haemophilus influenzae P652-8881 AXP35552.1    
 CH617_07615   Haemophilus influenzae P657-8759 AYO33719.1    
 CH621_03745   Haemophilus influenzae P662-7189 AXP77547.1    
 CH621_00625   Haemophilus influenzae P662-7189 AXP76994.1    
 CH624_03770   Haemophilus influenzae P665-7858 AXP61080.1    
 CH628_00875   Haemophilus influenzae P669-6977 AXP38922.1    
 CH628_04195   Haemophilus influenzae P669-6977 AXP39525.1    
 CH631_00605   Haemophilus influenzae P672-7661 AXP55470.1    
 CH631_03400   Haemophilus influenzae P672-7661 AXP55966.1    
 CH635_00625   Haemophilus influenzae P676-2514 AXP64009.1    
 CH635_03725   Haemophilus influenzae P676-2514 AXP64566.1    
 CH639_00630   Haemophilus influenzae P679-2791 AXP45157.1    
 CH639_03730   Haemophilus influenzae P679-2791 AXP45716.1    
 CGSHiEE_01240   Haemophilus influenzae PittEE ABQ97734.1    
 CGSHiEE_07715   Haemophilus influenzae PittEE ABQ98860.1    
 F8B64_00655   Haemophilus influenzae PittGG QFG54629.1    
 F8B64_03785   Haemophilus influenzae PittGG QFG55186.1    
 CGSHiGG_04570   Haemophilus influenzae PittGG ABQ99866.1    
 CGSHiGG_07845   Haemophilus influenzae PittGG ABR00418.1    
 R2846_0225 (Lic3A)   Haemophilus influenzae R2846 ADO95687.1    
 R2866_0221 (Lic3A)   Haemophilus influenzae R2866 ADO80211.1    
 HI0352 (fragment)   Haemophilus influenzae Rd KW20 CAA40567.1
AAC22013.1
NP_438516.1		    
 TA8730_01270 (fragment)   Haemophilus influenzae TA8730 BCR37513.1    
 TA8730_06630   Haemophilus influenzae TA8730 BCR38049.1    
 JPHIA_06440   Haemophilus influenzae TAMBA230 BCB15744.1    
 JPHIA_01270   Haemophilus influenzae TAMBA230 BCB15227.1    
 CMP-Neu5Ac: [LPS] α-2,3-sialyltransferase (Hac_1267; CsT) 2.4.3.6 Helicobacter acinonychis str. Sheeba CAK00017.1 Q17WF9  
 CMP-Neu5Ac: [LPS] α-2,6-sialyltransferase (Hac_1268; CsT) 2.4.3.3 Helicobacter acinonychis str. Sheeba CAK00018.1 Q17WF8  
 XJ32_01815   Helicobacter bilis AAQJH AQQ60625.1    
 XJ32_01810   Helicobacter bilis AAQJH AQQ59049.1    
 glycosyltransferase GT42 (Hbs1)   Helicobacter bizzozeronii 12A CCF72442.1    
 α-2,3-sialyltransferase, partial (Hbs2) (fragment)   Helicobacter bizzozeronii 12A CCF72443.1    
 α-2,3-sialyltransferase (Hbs2)   Helicobacter bizzozeronii CCUG 35546 CCF72447.1    
 HBZC1_02560 (Hβ-ST2)   Helicobacter bizzozeronii CIII-1 CCB79242.1    
 glycosyltransferase GT42 (Hbs1)   Helicobacter bizzozeronii Emo CCF72451.1    
 α-2,3-sialyltransferase, partial (Hbs2) (fragment)   Helicobacter bizzozeronii Emo CCF72452.1    
 α-2,3-sialyltransferase (Hbs2)   Helicobacter bizzozeronii Heydar CCF72456.1    
 glycosyltransferase GT42 (Hbs1)   Helicobacter bizzozeronii R53 CCF72460.1    
 α-2,3-sialyltransferase, partial (Hbs2) (fragment)   Helicobacter bizzozeronii R53 CCF72461.1    
 glycosyltransferase GT42 (Hbs1;Hβ-ST1)   Helicobacter bizzozeronii type strain: CCUG 35545 CCF72465.1    
 mono-functional α-2,3-sialyltransferase (Hbs2;Hβ-ST2) 2.4.3.4 Helicobacter bizzozeronii type strain: CCUG 35545 CCF72466.1 H2B3K3  
 glycosyltransferase GT42 (Hbs1)   Helicobacter bizzozeronii Yrjola CCF72470.1    
 α-2,3-sialyltransferase (Hbs2)   Helicobacter bizzozeronii Yrjola CCF72471.1    
 HCW_07285   Helicobacter cetorum MIT 00-7128 AFI04715.1    
 HCW_07290   Helicobacter cetorum MIT 00-7128 AFI04716.1    
 HCD_01680   Helicobacter cetorum MIT 99-5656 AFI05368.1    
 NCTC13205_00840   Helicobacter cholecystus NCTC13205 VEJ24687.1    
 BBW65_04570   Helicobacter enhydrae MIT 01-6242 ANV98117.1    
 Hfelis_02760   Helicobacter felis ATCC 49179 CBY82360.1    
 Hfelis_02750   Helicobacter felis ATCC 49179 CBY82359.1    
 Hfelis_08340 (fragment)   Helicobacter felis ATCC 49179 CBY82918.1    
 ASB1_03780 (fragment)   Helicobacter heilmannii ASB1 BDQ26702.1    
 ORF (short fragment)   Helicobacter heilmannii ASB1.4 CCM11093.1    
 HMU06130   Helicobacter mustelae 12198 CBG39874.1    
 NCTC12198_00642   Helicobacter mustelae NCTC12198 SQH71384.1    
 HPAKL86_02830   Helicobacter pylori Aklavik86 AFX89576.1    
 HPAKL86_02835   Helicobacter pylori Aklavik86 AFX89577.1    
 HPCU_04460   Helicobacter pylori Cuz20 ADO04052.1    
 HPCU_04470 (fragment)   Helicobacter pylori Cuz20 ADO04054.1    
 HPPN120_04170   Helicobacter pylori Puno120 AEN15449.1    
 HPPN135_04145   Helicobacter pylori Puno135 AEN18521.1    
 HPPN135_04150   Helicobacter pylori Puno135 AEN18522.1    
 HPSAT_02540   Helicobacter pylori Sat464 ADO05253.1    
 HPSAT_02545   Helicobacter pylori Sat464 ADO05254.1    
 HPSH169_04315   Helicobacter pylori Shi169 AFH99551.1    
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