GlycosylTransferase Family 42

Activities in FamilyCMP-Neu5Ac: α-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.3.3);
CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (EC 2.4.3.4);
CMP-Neu5Ac: N-acetyllactoside α-2,3-sialyltransferase (EC 2.4.3.6);
CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase (EC 2.4.3.8);
Mechanism Inverting
NoteThese enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resourcesCAZypedia;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (501); Uniprot accession (15); PDB accession (9); 3D entries (2); cryst (0)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 N8E86_09825   Avibacterium paragallinarum AG21-0333 UXN34343.1    
 N8E87_00445 (fragment)   Avibacterium paragallinarum AP-2 UXN37008.1    
 N8E87_00450 (fragment)   Avibacterium paragallinarum AP-2 UXN37009.1    
 IX83_00205   Basilea psittacipulmonis DSM 24701 AIL31956.1    
 LWF01_03415   Brevibacteriaceae bacterium ZFBP1038 WGW12837.1    
 CARM_1257 (CstI)   Campylobacter armoricus CCUG 73571 QKF80152.1    
 O8035_00550   Campylobacter coli 18JS15S WBO13395.1    
 A0X37_009205 (fragment)   Campylobacter coli 2014D-0143 QYH06879.1    
 A0X37_009200 (fragment)   Campylobacter coli 2014D-0143 QYH06878.1    
 A9468_005615   Campylobacter coli 2015D-0223 QYG99467.1    
 HXP32_03195 (fragment)   Campylobacter coli 20A420 QLD91851.1    
 α-2,3-sialyltransferase (NAcBN865_06990) (fragment)   Campylobacter coli 76339 CDG56934.1    
 BN865_09900c   Campylobacter coli 76339 CDG57207.1    
 BLD36_03840 (fragment)   Campylobacter coli BG2108 APA61360.1    
 BLD39_03810   Campylobacter coli BP3183 APA55841.1    
 K8351_01085   Campylobacter coli C203016 UAM78016.1    
 LAE74_06220   Campylobacter coli C203018 UAY57798.1    
 LAE76_05940   Campylobacter coli C203110 UAY59435.1    
 LAE75_05135   Campylobacter coli C203112 UAY60971.1    
 LAE73_05075   Campylobacter coli C203115 UAY62653.1    
 JMJ71_05960   Campylobacter coli CC19CH075 QUJ29858.1    
 JL476_05955   Campylobacter coli CC19CH076 QUJ31696.1    
 FOC43_01935   Campylobacter coli FDAARGOS_735 QGS19371.1    
 DSM101856_01139 (fragment)   Campylobacter coli meC0280 QOP70420.1    
 BLD37_00025 (fragment)   Campylobacter coli MG1116 APA53422.1    
 HK939_003500   Campylobacter coli P4581 UEZ84544.1    
 KPF77_06055   Campylobacter coli R19.0802 QWS21913.1    
 KPF78_03405 (fragment)   Campylobacter coli R19.0895 QWS24837.1    
 YSS_06160   Campylobacter coli RM4661 AHK77095.1    
 BLD33_02940   Campylobacter coli WA333 APA57443.1    
 NQK33_03300   Campylobacter coli YC3-24 UVN52780.1    
 BLD35_03835 (fragment)   Campylobacter coli YF2105 APA52343.1    
 A2J15_001230   Campylobacter hepaticus HV10 AXP08370.1    
 N3Z98_05925   Campylobacter hepaticus RBCL71delta WAP49292.1    
 N3Z98_04430   Campylobacter hepaticus RBCL71delta WAP49015.1    
 I5Q61_01240   Campylobacter hepaticus UF2019SK1 QPM44195.1    
 IRA69_05010   Campylobacter hepaticus USA52 QOW63402.1    
 CINS_1206 (CstI)   Campylobacter insulaenigrae NCTC 12927 AJC88165.1    
 NCTC12927_01227 (CstIII)   Campylobacter insulaenigrae NCTC12927 VEH95109.1    
 NCTC12928_01471   Campylobacter insulaenigrae NCTC12928 VEJ54963.1    
 CMV38_1224   Campylobacter jejuni 100 ATE69116.1    
 CLH93_1219   Campylobacter jejuni 104 ATD41753.1    
 CLH93_1418   Campylobacter jejuni 104 ATD41943.1    
 CGZ68_05690   Campylobacter jejuni 11168H/araE ASQ32344.1    
 CGZ70_05675   Campylobacter jejuni 11168H/lacY ASN48568.1    
 CJ12567_1082 (CstI)   Campylobacter jejuni 12567 AWB40613.1    
 HPE59_05535   Campylobacter jejuni 2016-IZSVE-19-111250 QKE04745.1    
 M635_01400   Campylobacter jejuni 32488 AGQ95598.1    
 CGZ78_05580   Campylobacter jejuni 81-176_G1_B0 ASN50138.1    
 CGZ84_05560   Campylobacter jejuni 81-176_G1_B7 ASQ33834.1    
 α-2,3-sialyltransferase (Cst-III)   Campylobacter jejuni ATCC 43429 AAK73183.1 Q7BP25  
 α-2,3-sialyltransferase (Cst-III)   Campylobacter jejuni ATCC 43430 AAK85419.1 Q7BP25  
 α-2,3-sialyltransferase (Cst-II) 2.4.3.4 Campylobacter jejuni ATCC 43432 AAG43979.1 Q9F0M9  
 α-2,3/8-sialyltransferase (CstII)   Campylobacter jejuni ATCC 43438 AAK91725.1    
 α-2,3/α-2,8-sialyltransferase II (CstII;Cst) 2.4.3.4
2.4.3.8
Campylobacter jejuni ATCC 43446 AAF34137.1
ADB45265.1
ADB45271.1
Q9L9Q5  
 bifunctional α-2,3/-2,8-sialyltransferase (Cst-II)   Campylobacter jejuni ATCC 43449 AAL06004.1    
 α-2,3-sialyltransferase (Cst-II) 2.4.3.4 Campylobacter jejuni ATCC 43456 AAL05990.1 Q93D05  
 α-2,3-sialyltransferase (CstI)   Campylobacter jejuni ATCC 43456 ADA70348.1    
 α-2,3-/α-2,8-sialyltransferase (CstII)   Campylobacter jejuni ATCC 43460 AAK96001.1 Q938X6  
 α-2,3/8-sialyltransferase (Cst-II) 2.4.3.4
2.4.3.8
Campylobacter jejuni ATCC 700297 AAL36462.1 Q9LAK3  
 BKM79_05700   Campylobacter jejuni BCW_6920 AOY03324.1    
 α-2,3/8-sialyltransferase (CstII)   Campylobacter jejuni BD-10 ADF30798.1
ADF30814.1
   
 α-2,3/8-sialyltransferase CstII   Campylobacter jejuni BD-22 ADN52706.1    
 FZN58_05635   Campylobacter jejuni BfR-CA-14430 QEP94053.1    
 α-2,3-/2,8-sialyltransferase (Cst-II) 2.4.3.4
2.4.3.8
Campylobacter jejuni CF 93-6 AAV52039.1 Q9LAK3  
 CstII   Campylobacter jejuni CF90-26 AAV80723.1    
 CPG33_03870   Campylobacter jejuni CFSAN032806 ATG65322.1    
 GH774_03860   Campylobacter jejuni CFSAN032806 QGG37087.1    
 GRN82_05430   Campylobacter jejuni CFSAN096296 QJE58372.1    
 GRO26_04035   Campylobacter jejuni CFSAN096302 QJE64183.1    
 GRO00_06535   Campylobacter jejuni CFSAN096305 QJE66340.1    
 GRO12_06060   Campylobacter jejuni CFSAN096306 QJE67965.1    
 GRO14_07065   Campylobacter jejuni CFSAN096307 QJE69752.1    
 AEI21_05385   Campylobacter jejuni CJ066CC508 AXL47252.1    
 AEI20_06945   Campylobacter jejuni CJ071CC464 AXL42484.1    
 AEI22_05145   Campylobacter jejuni CJ090CC1332 AXL43870.1    
 CRM98_06370   Campylobacter jejuni FDAARGOS_422 ATM02616.1    
 FORC46_1100   Campylobacter jejuni FORC_046 ASI87656.1    
 FORC46_1377   Campylobacter jejuni FORC_046 ASI87933.1    
 Cst-III (fragment)   Campylobacter jejuni GB1 ABL75152.1    
 α-2,3/α-2,8-sialyltransferase II (CstII;Cst) 2.4.3.4
2.4.3.8
Campylobacter jejuni GB11 AAR82875.1 Q9L9Q5  
 CstIII   Campylobacter jejuni GB13 ABL09028.1    
 CstIII   Campylobacter jejuni GB14 ABL09031.1    
 Cst-II   Campylobacter jejuni GB16 ABM74171.1    
 Cst-II   Campylobacter jejuni GB17 ABM68643.1    
 α-2,3-sialyltransferase (CstII)   Campylobacter jejuni GB18 ABI83629.1    
 α-2,3-sialyltransferase (Cst-II)   Campylobacter jejuni GB2 ABH09415.1    
 Cst-II   Campylobacter jejuni GB21 ABM74177.1    
 CstII   Campylobacter jejuni GB22 ABK63956.1    
 α-2,3-sialyltransferase (CstII)   Campylobacter jejuni GB23 ABL07605.1    
 Cst-II   Campylobacter jejuni GB25 ABM74208.1    
 α-2,3-sialyltransferase (CstII)   Campylobacter jejuni GB26 ABC73383.1    
 α-2,3-sialyltransferase (CstII) (fragment)   Campylobacter jejuni GB27 ABK91943.1    
 α-2,3-sialyltransferase (Cst-II)   Campylobacter jejuni GB28 ABK41255.1    
 α-2,3-sialyltransferase (Cst-II)   Campylobacter jejuni GB3 ABK41249.1    
 α-2,3-sialyltransferase (CstII)   Campylobacter jejuni GB31 CURA276 ABF67963.1    
 ORF   Campylobacter jejuni GB5 AAX45339.1    
 α-2,3 sialyltransferase (Cst-II)   Campylobacter jejuni GC-016 AKN20316.1    
 α-2,3 sialyltransferase (Cst-II)   Campylobacter jejuni GC-105 AKN20322.1    
 CstII   Campylobacter jejuni GC033 ABG00185.1    
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