Activities in Family	CMP-Neu5Ac: α-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.99.3); CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (EC 2.4.99.4); CMP-Neu5Ac: N-acetyllactoside α-2,3-sialyltransferase (EC 2.4.99.6); CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase (EC 2.4.99.8);
Mechanism	Inverting
Note	These enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resources	CAZypedia;
Commercial Enzyme Provider(s)	CHEMILY;
Statistics	GenBank accession (498); Uniprot accession (15); PDB accession (9); 3D entries (2); cryst (0)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
α-2,3-sialyltransferase (Cst-II)	2.4.99.4		Campylobacter jejuni ATCC 43432	AAG43979.1	Q9F0M9
α-2,3/α-2,8-sialyltransferase II (CstII;Cst)	2.4.99.4 2.4.99.8		Campylobacter jejuni ATCC 43446	AAF34137.1 ADB45265.1 ADB45271.1	Q9L9Q5
α-2,3-sialyltransferase (Cst-II)	2.4.99.4		Campylobacter jejuni ATCC 43456	AAL05990.1	Q93D05
α-2,3/8-sialyltransferase (Cst-II)	2.4.99.4 2.4.99.8		Campylobacter jejuni ATCC 700297	AAL36462.1	Q9LAK3
α-2,3-/2,8-sialyltransferase (Cst-II)	2.4.99.4 2.4.99.8		Campylobacter jejuni CF 93-6	AAV52039.1	Q9LAK3
α-2,3/α-2,8-sialyltransferase II (CstII;Cst)	2.4.99.4 2.4.99.8		Campylobacter jejuni GB11	AAR82875.1	Q9L9Q5
α-2,3-sialyltransferase (Cst-II)	2.4.99.4		Campylobacter jejuni MF8	AAZ80462.1	Q93D05
α-2,3-sialyltransferase (Cst-I)	2.4.99.4		Campylobacter jejuni OH4384	AAF13495.1 AAS36261.1 AAT23232.1	Q9RGF1	2P2V[A] 2P56[A]
bifunctional CMP-Neu5Ac: α-2,3/-2,8-sialyltransferase (CstII;Cst-II)	2.4.99.4 2.4.99.8		Campylobacter jejuni OH4384	AAF31771.1 AAO96668.1 AAT17965.1 ABA06995.1 ABA09514.1 ABH12650.1 ABI05854.1 ACK29125.1 CAF04166.1 CAK26615.1	Q9LAK3	1RO7[A,B,C,D] 1RO8[A,B] 2DRJ[A] 2WQQ[A] 2X61[A,B] 2X62[A,B] 2X63[A]
CJJ81176_1157	2.4.99.4 2.4.99.8	pubmed pubmed	Campylobacter jejuni subsp. jejuni 81-176	EAQ72171.1 AAL09368.1	A0A0H3P9T9 A1W0C6 Q9L9Q5
lipopolysaccharide α-2,3-/α-2,8-sialyltransferase (Lic3B)	2.4.99.4 2.4.99.8	pubmed pubmed	Haemophilus influenzae	ABD97878.1	Q1W2L3
CMP-Neu5Ac: [LPS] α-2,3-sialyltransferase (Hac_1267; CsT)	2.4.99.6		Helicobacter acinonychis str. Sheeba	CAK00017.1	Q17WF9
CMP-Neu5Ac: [LPS] α-2,6-sialyltransferase (Hac_1268; CsT)	2.4.99.3		Helicobacter acinonychis str. Sheeba	CAK00018.1	Q17WF8
mono-functional α-2,3-sialyltransferase (Hbs2;Hβ-ST2)	2.4.99.4		Helicobacter bizzozeronii type strain: CCUG 35545	CCF72466.1	H2B3K3
CMP-Neu5Ac: [galactosyl oligosaccharides / glycolipid] α-2,3-sialyltransferase 3 (PmST3;PM1174) (monofunctional)	2.4.99.4	pubmed	Pasteurella multocida subsp. multocida str. Pm70	AAK03258.1 NP_246111.1	Q9CLP3
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