Glycoside Hydrolase Family 99

Activities in Familyglycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130); mannan endo-1,2-α-mannanase (3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseUnclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton DonorGlu (experimental)
NoteCreated after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resourcesCAZypedia;
Statistics GenBank accession (152); Uniprot accession (30); PDB accession (18); 3D entries (2); cryst (0)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ACAM_0412   Aeropyrum camini SY1 = JCM 12091 BAN89881.1    
 APE_0727 (fragment)   Aeropyrum pernix K1 BAA79703.1    
 HALDL1_09485   Halobacterium sp. DL1 AHG05266.1    
 Pars_1633   Pyrobaculum arsenaticum DSM 13514 ABP51186.1    
 L593_09755   Salinarchaeum sp. Harcht-Bsk1 AGN01896.1    
 A3L01_02480   Thermococcus barossii SHCK-94 ASJ04282.1    
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