Glycoside Hydrolase Family 99

Activities in FamilyGlycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130);
Mannan endo-1,2-α-mannanase (EC 3.2.1.198);
Mechanism Retaining a
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseUnclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton DonorGlu (experimental)
NoteCreated after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resourcesCAZypedia;
Statistics GenBank accession (523); Uniprot accession (8); PDB accession (40); 3D entries (3); cryst (0)


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