Glycoside Hydrolase Family 99

Activities in Familyglycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130); mannan endo-1,2-α-mannanase (3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseUnclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton DonorGlu (experimental)
NoteCreated after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resourcesCAZypedia;
Statistics GenBank accession (152); Uniprot accession (30); PDB accession (18); 3D entries (2); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 endo-α-1,2-mannosidase (BtGH99;BT3862) (BtGH99) 3.2.1.130
3.2.1.-
Bacteroides thetaiotaomicron VPI-5482 AAO78967.1
NP_812773.1
Q8A109
4ACY[A,B] 1.69
4ACZ[A,B] 1.99
4AD0[A,B,C,D] 2.09
 endo-α-1,2-mannosidase (BxGH99;EndoMan;BXY_34140) (BxGH99) 3.2.1.130
3.2.1.-
Bacteroides xylanisolvens XB1A CBK68409.1 D6D1V7
4AD1[A] 1.90
4AD2[A,B,C,D] α-D-Glcp-(1-1)-<non_carb>
<carb_like_IFM>
2.10
4AD3[A,B,C,D] α-D-Glcp-(1-1)-<non_carb>
<carb_like_DMJ>
2.00
4AD4[A] α-D-Glcp-(1-1)-<non_carb>
α-D-Manp-(1-2)-β-D-Manp
<carb_like_IFM>
1.90
4AD5[A] α-D-Glcp-(1-1)-<non_carb>
α-D-Manp-(1-2)-α-D-Manp
<carb_like_DMJ>
1.90
4UTF[A] α-D-Manp-(1-1)-<non_carb>
α-D-Manp-(1-2)-α-D-Manp
<carb_like_IFM>
1.30
4V27[A] α-D-Manp-(1-1)-<non_carb>
<carb_like_IFM>
1.90
4V28[A] α-D-Manp-(1-3)-α-D-Manp-(1-1)-<non_carb>
1.20
5LYR[A] α-D-Manp-(1-1)-<non_carb>
<carb_like_MNM>
1.14
5M03[A] α-D-Manp-(1-1)-<non_carb>
α-D-Manp-(1-2)-α-D-Manp
<carb_like_MNM>
1.05
5M17[A] α-D-Manp-(1-3)-D-1,2-deoxy-Glcp
1.03
5M3W[A] α-D-Manp-(1-2)-α-D-Manp
α-D-Manp-(1-3)-D-1,2-deoxy-Glcp
1.04
5M5D[A] α-D-Manp-(1-3)-D-1,2-deoxy-Glcp
1.07
5MC8[A] α-D-Manp-(1-2)-α-D-Manp
α-D-Manp-(1-3)-D-1,2-deoxy-Glcp
1.18
5MEL[A] α-D-Glcp-(1-1)-<non_carb>
1.20
Top


Last update: 2017-11-06 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille