| Activities in Family | Acholetin phosphorylase (EC 2.4.1.-);
β-1,4-glucosyl-N-acetylglucosamine phosphorylase (EC 2.4.1.-);
β-1,4-glucosylgalactose phosphorylase (EC 2.4.1.-);
Mixed-linkage β-glucooligosaccharide phosphorylase (EC 2.4.1.-);
Cellobiose phosphorylase (EC 2.4.1.20);
Chitobiose phosphorylase (EC 2.4.1.280);
Laminaribiose phosphorylase (EC 2.4.1.31);
Cellobionic acid phosphorylase (EC 2.4.1.321);
β-1,2-oligoglucan phosphorylase (EC 2.4.1.333);
Solabiose phosphorylase (EC 2.4.1.389);
3-O-β-D-glucopyranosyl β-D-glucuronide phosphorylase (EC 2.4.1.392);
Cellodextrin phosphorylase (EC 2.4.1.49);
|
|---|
| Mechanism | Inverting e |
|---|
| Clan | GH-Q |
|---|
| 3D Structure Status | ( α / α ) 6 barrel |
|---|
| Catalytic Nucleophile/Base | phosphate |
|---|
| Catalytic Proton Donor | Asp |
|---|
| Note | Formerly known as glycosyltransferase family GT36; Assigned to a GH family following a paper by Hidaka, Honda, Kitaoka, Nirasawa, Hayashi, Wakagi, Shoun and Fushinobu (Structure (Camb). 2004 Jun;12(6):937-947) (PMID: 15274915) that revealed the evolutionary, structural and mechanistic relationship of these phosphorylases with glycoside hydrolases of clan GH-L. |
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| External resources | CAZypedia; |
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| Statistics | GenBank accession (5971); Uniprot accession (46); PDB accession (40); 3D entries (9); cryst (0) |
|---|
|
| Bacteria |
| Protein Name | EC# | Reference | Organism | GenBank |
Uniprot | PDB/3D | |
| cellodextrin-phosphorylase (Cdp; CtCDP; RtCDP; Cthe_2989) |
2.4.1.49 |
doi
|
Acetivibrio thermocellus ATCC 27405
|
ABN54185.1
BAA22081.1 |
A3DJQ6
O24780
Q93HT8 |
5NZ7[A,B]
5NZ8[A,B]
8H2K[A,B]
8H2V[A,B]
8H2W[A,B]
8H6H[A,B]
8HNU[A,B] |
|
| cellobiose phosphorylase (Cbp; CtCBP; RtCBD; Cthe_0275) |
2.4.1.20 |
pubmed
|
Acetivibrio thermocellus ATCC 27405
|
ABN51514.1 |
A3DC35 |
|
|
| cellodextrin phosphorylase (Cdp-ym4) |
2.4.1.49 |
pubmed
|
Acetivibrio thermocellus YM4
|
BAB71818.1 |
Q93HT8 |
|
|
| cellobiose phosphorylase (Cbp) |
2.4.1.20 |
pubmed
|
Acetivibrio thermocellus YM4
|
AAL67138.1 |
Q8VP44 |
3QDE[A,B]
8HO7[A,B]
8HO8[A,B]
8HO9[A,B] |
|
| cellobiose-phosphorylase (Cbp) |
2.4.1.20 |
pubmed
|
Acetivibrio thermocellus YM4
|
BAA25846.1 |
O66383 |
|
|
| laminaribiose phosphorylase (ACL_0729;ACL0729) |
2.4.1.31 |
pubmed
|
Acholeplasma laidlawii PG-8A
|
ABX81345.1 |
A9NG65 |
|
|
| acholetin phosphorylase (AchP; ACL_1061) |
2.4.1.- |
pubmed
|
Acholeplasma laidlawii PG-8A
|
ABX81671.1 |
A9NH41 |
|
|
| mixed-linkage β-glucooligosaccharide phosphorylase (BpGH94MLG; E5259_00910) |
2.4.1.- |
pubmed
|
Blautia producta DSM 2950
|
QMW76265.1 |
|
8BOU[A,B] |
|
| cyclic β-1,2-glucan synthetase / cyclic glucan synthase (Cgs) |
2.4.1.333 |
pubmed
|
Brucella abortus S19
|
ACD71661.1
AAC34747.1
AAC34747.2 |
A0A0F6ANM6
B2S8A8
O85166 |
|
|
| cellobiose phosphorylase (Cbp;CgCBP) |
2.4.1.20 |
pubmed
|
Cellulomonas gilvus ATCC13127
|
BAA28631.1 |
O66264 |
2CQS[A,B]
2CQT[A,B]
3ACS[A,B]
3ACT[A,B]
3AFJ[A,B]
3QFY[A,B]
3QFZ[A,B]
3QG0[A,B] |
|
| cellobiose phosphorylase (CbP) |
2.4.1.20 |
doi
|
Cellulomonas uda DSM 20108
|
AAQ20920.1 |
Q7WTR6 |
3RRS[A,B]
3RSY[A,B]
3S4A[A,B]
3S4B[A,B]
3S4C[A]
3S4D[A] |
|
| 4-O-β-D-glucosyl-N-acetyl-D-glucosamine phosphorylase (IaGP; IALB_1006) |
2.4.1.- |
pubmed
|
Ignavibacterium album JCM 16511
|
AFH48717.1 |
I0AIB0 |
|
|
| β-1,2-oligoglucan phosphorylase (LpSOGP;Cphy_0694) |
2.4.1.333 |
pubmed
|
Lachnoclostridium phytofermentans ISDg
|
ABX41081.1 |
A9KJS6 |
5H3Z[A,B]
5H40[A,B]
5H41[A,B]
5H42[A,B] |
|
| β-1,2-oligoglucan phosphorylase (LiSOGP; Lin1839) |
2.4.1.333 |
pubmed
|
Listeria innocua Clip11262
|
CAC97070.1
NP_471174.1 |
Q92AT0 |
|
|
| 3-O-β-D-glucopyranosyl β-D-glucuronide phosphorylase (PBOR_13355) |
2.4.1.392 |
doi
|
Paenibacillus borealis DSM 13188
|
AIQ57809.1 |
A0A089MMR2 |
|
|
| solabiose phosphorylase (PBOR_28850) |
2.4.1.389 |
pubmed
|
Paenibacillus borealis DSM 13188
|
AIQ60507.1 |
A0A089LI24 |
|
|
| 4-O-β-D-glucosyl-D-galactose phosphorylase (GGalP; PpGGalP; X809_13280) |
2.4.1.389
2.4.1.- |
pubmed
|
Paenibacillus polymyxa CR1
|
AHC20114.1
AHC20112.2 |
|
|
|
| laminaribiose phosphorylase (LbpA) |
2.4.1.31 |
pubmed
|
Paenibacillus sp. YM1
|
BAJ10826.1 |
D7UT17 |
6GGY[A,B]
6GH2[A,B]
6GH3[A,B] |
|
| cellodextrin phosphorylase (CdpA; Ccel_1439) |
2.4.1.49 |
pubmed
|
Ruminiclostridium cellulolyticum H10
|
ACL75793.1 |
B8I1W7 |
|
|
| cellodextrin phisphorylase (CdpC; Ccel_3412) |
2.4.1.49 |
pubmed
|
Ruminiclostridium cellulolyticum H10
|
ACL77700.1 |
B8I1R5 |
|
|
| cellobiose phosphorylase (CbpA;Ccel_2109) |
2.4.1.20 |
pubmed
|
Ruminiclostridium cellulolyticum H10
|
ACL76454.1 |
B8I421 |
|
|
| cellodextrin phosporylase (CdpB; Ccel_2354) |
2.4.1.49 |
pubmed
|
Ruminiclostridium cellulolyticum H10
|
ACL76688.1 |
B8I5F2 |
|
|
| cellobiose phosphorylase (CBP;RaCBP;Rumal_0187) |
2.4.1.20 |
pubmed
|
Ruminococcus albus 7 = DSM 20455
|
ADU20744.1 |
E0LCW6
E6UCF2 |
|
|
| cellodextrin phosphorylase (CDP;RaCDP;Rumal_2403) |
2.4.1.49 |
pubmed
|
Ruminococcus albus 7 = DSM 20455
|
ADU22883.1 |
E0L4C3
E6UE18 |
|
|
| cellobionic acid phosphorylase 94B (Cep94B;CBAP;SdCBAP;Sde_0906) (Cep94B) |
2.4.1.321 |
pubmed
|
Saccharophagus degradans 2-40
|
ABD80168.1 |
Q21MB1 |
4ZLE[A]
4ZLF[A]
4ZLG[A]
4ZLI[A] |
|
| cellobiose phosphorylase 94A (Cbp;SdCBP;Sde_1318) (Cep94A) |
2.4.1.20 |
pubmed
|
Saccharophagus degradans 2-40
|
ABD80580.1 |
Q21L49 |
|
|
| cellodextrin-phosphorylase (CepB;CsCdP) |
2.4.1.49 |
pubmed
|
Thermoclostridium stercorarium DSM8532
|
AAC45511.1 |
P77846 |
|
|
| cellobiose-phosphorylase (CepA) |
2.4.1.20 |
pubmed
|
Thermoclostridium stercorarium NCIB 11754
|
AAC45510.1 |
Q59316 |
|
|
| cellobiose-phosphorylase (CepA;TM1848;Tmari_1863) |
2.4.1.20 |
pubmed
|
Thermotoga maritima MSB8
|
AAD36910.1
AGL50787.1
AHD18255.1
AKE29604.1
NP_229644.1 |
Q9X2G3
R4P2E1 |
|
|
| cellobiose-phosphorylase (CbpA) |
2.4.1.20 |
pubmed
|
Thermotoga neapolitana DSM 4359
|
AAB95491.2
ACM22959.1 |
B9K7M6
O52504 |
|
|
| cellobiose phosphorylase (GH94_G) |
2.4.1.20 |
pubmed
|
uncultured bacterium
|
QCO92836.1 |
A0A4P8GF30 |
|
|
| cellodextrin phosphorylase (GH94_F) |
2.4.1.49 |
pubmed
|
uncultured bacterium
|
QCO92835.1 |
A0A4P8GE33 |
|
|
| laminaribiose phosphorylase (GH94_B) |
2.4.1.31 |
pubmed
|
uncultured bacterium
|
QCO92990.1 |
A0A4P8GFQ2 |
|
|
| laminaribiose phosphorylase (GH94_C) |
2.4.1.31 |
pubmed
|
uncultured bacterium
|
QCO92945.1
QCO93023.1
QCO93046.1 |
A0A4P8GE90 |
|
|
| cellobiose phosphorylase (GH94_E) |
2.4.1.20 |
pubmed
|
uncultured bacterium
|
QCO92799.1 |
A0A4P8GDW8 |
|
|
| cellodextrin phosphorylase (GH94_A) |
2.4.1.49 |
pubmed
|
uncultured bacterium
|
QCO92991.1 |
A0A4P8GG51 |
|
|
| cellodextrin phosphorylase (GH94_D) |
2.4.1.49 |
pubmed
|
uncultured bacterium
|
QCO92946.1
QCO93024.1
QCO93047.1 |
A0A4V1E8I4 |
|
|
| diacetylchitobiose phosphorylase (ChbP) |
2.4.1.280 |
pubmed
|
Vibrio furnissii
|
AAG23740.1 |
Q9F8X1 |
|
|
| chitobiose phosphorylase (ChbP;VpChBP) |
2.4.1.280 |
pubmed
|
Vibrio proteolyticus
|
BAC87867.1 |
Q76IQ9 |
1V7V[A]
1V7W[A]
1V7X[A] |
|
| cellobionic acid phosphorylase (CelAP; NdvB; XCC4077) |
2.4.1.321 |
pubmed
|
Xanthomonas campestris pv. campestris str. ATCC 33913
|
AAM43298.1
NP_639416.1 |
Q8P3J4 |
|
|
| Eukaryota |
| Protein Name | EC# | Reference | Organism | GenBank |
Uniprot | PDB/3D | |
| cellobionic acid phosphorylase (CelAP;NdvB;NCU09425) |
2.4.1.321 |
pubmed
|
Neurospora crassa OR74A
|
EAA28929.1
XP_332117.1 |
Q7S0S2 |
|
|
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