Glycoside Hydrolase Family 94

Activities in FamilyAcholetin phosphorylase (EC 2.4.1.-);
β-1,4-glucosyl-N-acetylglucosamine phosphorylase (EC 2.4.1.-);
β-1,4-glucosylgalactose phosphorylase (EC 2.4.1.-);
Mixed-linkage β-glucooligosaccharide phosphorylase (EC 2.4.1.-);
Cellobiose phosphorylase (EC 2.4.1.20);
Chitobiose phosphorylase (EC 2.4.1.280);
Laminaribiose phosphorylase (EC 2.4.1.31);
Cellobionic acid phosphorylase (EC 2.4.1.321);
β-1,2-oligoglucan phosphorylase (EC 2.4.1.333);
Solabiose phosphorylase (EC 2.4.1.389);
3-O-β-D-glucopyranosyl β-D-glucuronide phosphorylase (EC 2.4.1.392);
Cellodextrin phosphorylase (EC 2.4.1.49);
Mechanism Inverting e
ClanGH-Q
3D Structure Status( α / α ) 6 barrel
Catalytic Nucleophile/Basephosphate
Catalytic Proton DonorAsp
NoteFormerly known as glycosyltransferase family GT36; Assigned to a GH family following a paper by Hidaka, Honda, Kitaoka, Nirasawa, Hayashi, Wakagi, Shoun and Fushinobu (Structure (Camb). 2004 Jun;12(6):937-947) (PMID: 15274915) that revealed the evolutionary, structural and mechanistic relationship of these phosphorylases with glycoside hydrolases of clan GH-L.
External resourcesCAZypedia;
Statistics GenBank accession (6118); Uniprot accession (49); PDB accession (46); 3D entries (10); cryst (0)


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