Activities in Family	Chitosanase (EC 3.2.1.132); Reducing end-acting cellobiohydrolase (EC 3.2.1.176); Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Mechanism	Retaining e
Clan	GH-B
3D Structure Status	β-jelly roll
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	formerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resources	CAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (10861); Uniprot accession (105); PDB accession (97); 3D entries (23); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
CbhI (fragment)		uncultured fungus	CBK52730.1
CbhI (fragment)		uncultured fungus	CBK52731.1
CbhI (fragment)		uncultured fungus	CBK52732.1
CbhI (fragment)		uncultured fungus	CBK52733.1
CbhI (fragment)		uncultured fungus	CBK52734.1
CbhI (fragment)		uncultured fungus	CBK52735.1
CbhI (fragment)		uncultured fungus	CBK52736.1
CbhI (fragment)		uncultured fungus	CBK52737.1
CbhI (fragment)		uncultured fungus	CBK52738.1
CbhI (fragment)		uncultured fungus	CBK52739.1
CbhI (fragment)		uncultured fungus	CBK52741.1
CbhI (fragment)		uncultured fungus	CBK52742.1
CbhI (fragment)		uncultured fungus	CBK52743.1
CbhI (fragment)		uncultured fungus	CBK52744.1
CbhI (fragment)		uncultured fungus	CBK52745.1
CbhI (fragment)		uncultured fungus	CBK52747.1
CbhI (fragment)		uncultured fungus	CBK52748.1
CbhI (fragment)		uncultured fungus	CBK52750.1
CbhI (fragment)		uncultured fungus	CBK52751.1
CbhI (fragment)		uncultured fungus	CBK52752.1
CbhI (fragment)		uncultured fungus	CBK52753.1
CbhI (fragment)		uncultured fungus	CBK52755.1
CbhI (fragment)		uncultured fungus	CBK52756.1
CbhI (fragment)		uncultured fungus	CBK52757.1
CbhI (fragment)		uncultured fungus	CBK52759.1
CbhI (fragment)		uncultured fungus	CBK52761.1
CbhI (fragment)		uncultured fungus	CBK52763.1
CbhI (fragment)		uncultured fungus	CBK52764.1
CbhI (fragment)		uncultured fungus	CBK52765.1
CbhI (fragment)		uncultured fungus	CBK52766.1
CbhI (fragment)		uncultured fungus	CBK52767.1
CbhI (fragment)		uncultured fungus	CBK52768.1
CbhI (fragment)		uncultured fungus	CBK52770.1
CbhI (fragment)		uncultured fungus	CBK52771.1
CbhI (fragment)		uncultured fungus	CBK52772.1
CbhI (fragment)		uncultured fungus	CBK52773.1
CbhI (fragment)		uncultured fungus	CBK52774.1
CbhI (fragment)		uncultured fungus	CBK52776.1
CbhI (fragment)		uncultured fungus	CBK52777.1
CbhI (fragment)		uncultured fungus	CBK52779.1
CbhI (fragment)		uncultured fungus	CBK52780.1
CbhI (fragment)		uncultured fungus	CBK52781.1
CbhI (fragment)		uncultured fungus	CBK52782.1
CbhI (fragment)		uncultured fungus	CBK52783.1
CbhI (fragment)		uncultured fungus	CBK52784.1
CbhI (fragment)		uncultured fungus	CBK52785.1
CbhI (fragment)		uncultured fungus	CBK52786.1
CbhI (fragment)		uncultured fungus	CBK52789.1
CbhI (fragment)		uncultured fungus	CBK52790.1
CbhI (fragment)		uncultured fungus	CBK52791.1
CbhI (fragment)		uncultured fungus	CBK52793.1
CbhI (fragment)		uncultured fungus	CBK52794.1
CbhI (fragment)		uncultured fungus	CBK52798.1
CbhI (fragment)		uncultured fungus	CBK52799.1
CbhI (fragment)		uncultured fungus	CBK52800.1
CbhI (fragment)		uncultured fungus	CBK52801.1
CbhI (fragment)		uncultured fungus	CBK52803.1
CbhI (fragment)		uncultured fungus	CBK52804.1
CbhI (fragment)		uncultured fungus	CBK52807.1
CbhI (fragment)		uncultured fungus	CBK52808.1
CbhI (fragment)		uncultured fungus	CBK52809.1
CbhI (fragment)		uncultured fungus	CBK52810.1
CbhI (fragment)		uncultured fungus	CBK52811.1
CbhI (fragment)		uncultured fungus	CBK52813.1
CbhI (fragment)		uncultured fungus	CBK52817.1
CbhI (fragment)		uncultured fungus	CBK52818.1
CbhI (fragment)		uncultured fungus	CBK52819.1
CbhI (fragment)		uncultured fungus	CBK52820.1
CbhI (fragment)		uncultured fungus	CBK52821.1
CbhI (fragment)		uncultured fungus	CBK52822.1
CbhI (fragment)		uncultured fungus	CBK52823.1
CbhI (fragment)		uncultured fungus	CBK52824.1
CbhI (fragment)		uncultured fungus	CBK52825.1
CbhI (fragment)		uncultured fungus	CBK52826.1
CbhI (fragment)		uncultured fungus	CBK52827.1
CbhI (fragment)		uncultured fungus	CBK52828.1
CbhI (fragment)		uncultured fungus	CBK52829.1
CbhI (fragment)		uncultured fungus	CBK52830.1
CbhI (fragment)		uncultured fungus	CBK52831.1
CbhI (fragment)		uncultured fungus	CBK52832.1
CbhI (fragment)		uncultured fungus	CBK52833.1
CbhI (fragment)		uncultured fungus	CBK52835.1
CbhI (fragment)		uncultured fungus	CBK52836.1
CbhI (fragment)		uncultured fungus	CBK52838.1
CbhI (fragment)		uncultured fungus	CBK52839.1
GH7 (C2_C3) (fragment)		uncultured fungus	AAS79365.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10563.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10564.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10578.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10555.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10568.1
cellobiohydrolase I, partial (CbhI) (fragment)		uncultured fungus	QJI10545.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10547.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10576.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10557.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10566.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10549.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10558.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10551.1
cellobiohydrolase I, partial (fragment)		uncultured fungus	QJI10561.1
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