Glycoside Hydrolase Family 7

Activities in Familyendo-β-1,4-glucanase (EC 3.2.1.4); reducing end-acting cellobiohydrolase (EC 3.2.1.176); chitosanase (EC 3.2.1.132); endo-β-1,3-1,4-glucanase (EC 3.2.1.73)
Mechanism Retaining
ClanGH-B
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (10567); Uniprot accession (528); PDB accession (84); 3D entries (17); cryst (0)
All (5102) Bacteria (10) Eukaryota (5088) unclassified (4) Structure (17) Characterized (84)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 cellobiohydrolase (Cbh1;ActCbh1) (Cel7A) 3.2.1.176 Acremonium thermophilum ALKO4245 CAM98445.1 A7WNT9  
 cellobiohydrolase (Cel7B) 3.2.1.176 Acremonium thermophilum ALKO4245 CAM98446.1 A7WNU0  
 cellobiohydrolase I / chitosanase (CBHI) 3.2.1.176
3.2.1.132
Aspergillus aculeatus F-50 BAA25183.1 O59843  
 cellobiohydrolase (Cbh1;NFIA_057300) 3.2.1.176 Aspergillus fischeri NRRL 181 EAW16381.1
XP_001258278.1
A1DNL0  
 cellobiohydrolase B (CbhB;AFUA_6G11610) (Cel7A) 3.2.1.176 Aspergillus fumigatus Af293 EAL89006.1 Q4WM08 4V1Z[A]
4V20[A]
 cellobiohydrolase (CbhB) 3.2.1.176 Aspergillus nidulans AAM54070.1 Q8NK02  
 endo-β-1,4-glucanase (EglB) 3.2.1.4 Aspergillus nidulans AAM54071.1 Q5B7R2
Q8NK01
 
 cellobiohydrolase I (CBHI;CbhB;AN0494.2) 3.2.1.176 Aspergillus nidulans FGSC A4 EAA66593.1 Q8NK02  
 endo-β-1,4-glucanase (EglB;AN3418.2) 3.2.1.4 Aspergillus nidulans FGSC A4 EAA63386.1 C8VHK3
Q5B7R2
 
 cellobiohydrolase B (CbhB;An01g11660) 3.2.1.176 Aspergillus niger CBS 513.88 AAF04492.1
AAP66264.1
CAK44068.1
Q9UVS8  
 cellobiohydrolase A (CbhA;An07g09330) 3.2.1.176 Aspergillus niger CBS 513.88 AAF04491.1
AAP66263.1
AAR79028.1
CAK39699.1
Q9UVS9  
 endo-β-1,4-glucanase (CelB) 3.2.1.4 Aspergillus oryzae KBN616 BAA22589.1 F5BB84
O13455
Q2TX26
 
 endo-β-1,4-glucanase (CelB;AO090010000314) 3.2.1.4 Aspergillus oryzae RIB40 BAE66197.1
AEB00821.1
Q2TX26  
 cellobiohydrolase I (Cel1) 3.2.1.176 Bipolaris zeicola AAC49089.1 Q00328  
 endo-β-1,3-1,4-glucanase (Bgl7A) 3.2.1.4
3.2.1.73
Bispora sp. MEY-1 / CGMCC 2500 ACT53749.1 D2DRB6  
 cellobiohydrolase (Cbh1;CtCbh1) (Cel7A) 3.2.1.176 Chaetomium thermophilum ALKO4265 CAM98448.1 A7WNU1  
 cellobiohydrolase (Cbh1;EG7-1) (Cel7A) 3.2.1.176 Chaetomium thermophilum CT2 AAW64926.1
AGY80096.1
Q5G2D5  
 cellobiohydrolase (Cbh3) 3.2.1.176 Chaetomium thermophilum CT2 AAY89412.2
ABN13116.1
Q4JI68  
 cellobiohydrolase Ia (Cbh1a;CBH Ia) (Cel7A) 3.2.1.176 Chrysosporium lucknowense AAQ38146.1
ACH15004.1
ACH15013.1
   
 cellobiohydrolase I (Cel1) 3.2.1.176 Claviceps purpurea T5 CAA68840.1 O00082  
 endo-β-1,4-glucanase (CLhgEG1) 3.2.1.4 Coptotermes lacteus symbiont WH2002 BAC07551.1 Q8MXY2  
 endo-β-1,4-glucanase (CLhgEG2) 3.2.1.4 Coptotermes lacteus symbiont WH2002 BAC07552.1 Q8MXY1  
 cellobiohydrolase I (CBH1;Cel7) (Cel7B) 3.2.1.176 Dichomitus squalens FBCC312 CDJ79665.1    
 cellobiohydrolase I (CbhA;DdiCel7A;DDB_G0268446) (Cel7A) 3.2.1.176 Dictyostelium discoideum AX4 EAL73676.1   4ZZQ[A]
 cellobiohydrolase (DpuCel7A;DICPUDRAFT_151874) 3.2.1.176 Dictyostelium purpureum QSDP1 EGC35742.1   4ZZP[A,B]
 cellobiohydrolase (FvCel7B) (Cel7B) 3.2.1.176 Flammulina velutipes Fv-1 BAJ07535.1 D5MSJ4  
 cellobiohydrolase (FvCel7A) (Cel7A) 3.2.1.176 Flammulina velutipes Fv-1 BAJ07534.1 D5MSJ3  
 endo-β-1,4-glucanase I (EG I;Eg1;Fof7) (Cel7B) 3.2.1.4 Fusarium oxysporum AAA65586.1
AAE25069.1
AAG09047.1
P46237 1OVW[A,B,C,D]
2OVW[A,B,C,D]
3OVW[A,B]
4OVW[A,B]
 cellobiohydrolase I (CbhI) 3.2.1.176 Fusicoccum sp. BCC4124 ABS82449.1 A7LN91  
 cellobiohydrolase 1 (HirCel7A;38802) (Cel7A) 3.2.1.176 Heterobasidion irregulare TC 32-1     2XSP[A]
2YG1[A,B]
 endoglucanase 3 (HmEG3) (fragment) 3.2.1.4 Holomastigotoides mirabile BAB64565.1 Q95P29  
 endoglucanase 2 (HmEG2) 3.2.1.4 Holomastigotoides mirabile BAB64564.1 Q95P30  
 endoglucanase 1 (HmEG1) 3.2.1.4 Holomastigotoides mirabile BAB64563.1 Q95P31  
 cellobiohydrolase I (Cbh1.1;Cbh1;Cbh-1;HgCbh1) (Cel7A) 3.2.1.176 Humicola grisea var. thermoidea CAA35159.1 P15828  
 endo-β-1,4-glucanase I (Egl1;EG-I) 3.2.1.4 Humicola grisea var. thermoidea BAA09786.1 Q12622  
 cellobiohydrolase I.2 (Cbh1.2) 3.2.1.176 Humicola grisea var. thermoidea AAD31545.1
AAD11942.1
AAN19007.1
O94093
Q7LV60
 
 cellobiohydrolase I (Exo1) 3.2.1.176 Humicola grisea var. thermoidea IFO9854 BAA74517.1 O93780  
 cellobiohydrolase (Cbh-1;HgtCel7A) (Cel7A) 3.2.1.176 Humicola grisea var. thermoidea IFO9854 / CBS 225.63 BAA09785.1 Q12621 4CSI[A,B]
 endoglucanase I (EG I;EG1) (Cel7B) 3.2.1.4 Humicola insolens AAE25068.1
AAE25070.1
P56680 1A39[A]
1DYM[A]
1OJI[A]
1OJJ[A,B]
1OJK[A,B]
2A39[A,B]
 exo-cellulase (Cel1;Ex-1) 3.2.1.176 Irpex lacteus MC-2 BAA76363.1 Q9Y722  
 cellobiohydrolase II (Cel2;Ex-2) 3.2.1.176 Irpex lacteus MC-2 BAA76364.1 Q9Y723  
 cellobiohydrolase (GH7B;LqCel7B) (Cel7B) 3.2.1.176 Limnoria quadripunctata ADB85438.1 D4HRL0 4GWA[A,B]
4HAP[A,B]
4HAQ[A,B]
4IPM[A]
 cellobiohydrolase (MG10712.4) (Cel7A) 3.2.1.176 Magnaporthe oryzae 70-15 XP_367082.1 G4NIA4  
 cellobiohydrolase (Gh7;MaCel7B) (Cel7B) 3.2.1.176 Melanocarpus albomyces CBS 638.94 CAD56667.1
AAU96164.1
CAD79785.1
CDF76454.1
Q8J0K6 2RFW[A,B,C,D]
2RFY[A,B,C,D]
2RFZ[A,B,C,D]
2RG0[A,B,C,D]
 cellobiohydrolase / cellulase I 3.2.1.176 Mycothermus thermophilus CBS 619.91 CAD79780.1    
 cellobiohydrolase (Cbh-1;CBH1;NCU07340) 3.2.1.176 Neurospora crassa OR74A EAA33262.1
XP_327626.1
Q7SA23  
 cellobiohydrolase I (Cbh1;CbhI;PcCel7A) (Cel7A) 3.2.1.176 Penicillium canescens F-178 / RN3-11-7 AIL95870.1    
 cellobiohydrolase 1 (CbhI) 3.2.1.176 Penicillium chrysogenum FS010 AAV65115.1
AAX84833.1
Q5S1P9  
 cellobiohydrolase (Cbh1;CBHI;CBH Ib) (Cel7A) 3.2.1.176 Penicillium decumbens 114-2 ACV95805.1 C9EI49  
 endoglucanase I / 7B (Eg1;Egl1) (Cel7B) 3.2.1.4 Penicillium decumbens 114-2 / JU-A10 ABY56790.1 B0FMT4  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Penicillium janthinellum Biourge IMET 43733 (C41) CAA41780.1 Q06886  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Penicillium occitanis Pol6 AAT99321.1 Q68HC2  
 cellobiohydrolase I-1 (Cbh1;CBH62;PcCel7C) (Cel7C) 3.2.1.176 Phanerochaete chrysosporium CAA80253.1
AAB46373.1
P13860  
 cellobiohydrolase I-2 (CBH58;CbhI.2;CbhI-4;PcCel7D) (Cel7D) 3.2.1.176 Phanerochaete chrysosporium CAA82761.1
AAA19802.1
CAA77789.1
CAA77795.1
CAA80252.1
CAA82762.1
Q09431
Q7LHI2
1GPI[A]
1H46[X]
1Z3T[A]
1Z3V[A]
1Z3W[A]
 cellobiohydrolase (Cbh1-1) (Cel7A) 3.2.1.176 Phanerochaete chrysosporium BKM-1767 AAA09708.1
CAA38274.1
Q01762  
 endoglucanase 3 (PgEG3) 3.2.1.4 Pseudotrichonympha grassii BAB64562.1 Q95YH3  
 endoglucanase 2 (PgEG2) 3.2.1.4 Pseudotrichonympha grassii BAB64561.1 Q95YH4  
 endoglucanase 1 (PgEG1h) 3.2.1.4 Pseudotrichonympha grassii BAB64553.1
BAB64554.1
BAB64555.1
BAB64556.1
BAB64557.1
BAB64558.1
BAB64559.1
BAB64560.1
Q95NK6
Q95P32
 
 cellobiohydrolase 1 (Cbh1A;CBH IB;TeCbh1;ReCel7A) (Cel7A) 3.2.1.176 Rasamsonia emersonii IMI 392299 AAL89553.1
AAL33603.2
Q8TFL9 1Q9H[A]
3PFJ[A]
3PFX[A]
3PFZ[A]
3PL3[A]
 cellobiohydrolase I / 7A (TCE0_004r00180) (Cel7A) 3.2.1.176 Talaromyces cellulolyticus Y-94 GAM33347.1    
 endo-β-1,4-glucanase 7B (TCE0_024r07350) (Cel7B) 3.2.1.4 Talaromyces cellulolyticus Y-94 GAM37432.1    
 cellobiohydrolase (XynA) 3.2.1.176 Talaromyces funiculosus IMI 378536 CAC85737.1
AAP60302.1
CAC07539.1
Q8WZJ4  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Talaromyces funiculosus NCL1 ADX60067.1   4XEB[A]
 cellobiohydrolase (Cel7A) 3.2.1.176 Thermoascus aurantiacus ALKO4242 CAM98447.1
CAD79781.1
A7WNU2  
 cellobiohydrolase (Cbh1;TaCel7A) (Cel7A) 3.2.1.176 Thermoascus aurantiacus IFO 9748 AAL83303.1
AAL16941.1
Q8TG37
Q96UR5
 
 endo-β-1,4-glucanase (Eg7a;MtEG7a;MYCTH_111372) 3.2.1.4 Thermothelomyces thermophila ATCC 42464 AEO58196.1    
 cellobiohydrolase (Cel7A) 3.2.1.176 Thielavia australiensis CAD79782.1    
 cellobiohydrolase (THITE_118360) (Cel7A) 3.2.1.176 Thielavia terrestris NRRL 8126 AEO67172.1    
 cellobiohydrolase I (Cbh1;ThCBHI;ThCel7A) (Cel7A) 3.2.1.176 Trichoderma harzianum FP 108 / IOC-3844 AAF36391.1 Q9P8P3 2Y9L[A]
2Y9N[A]
2YOK[A]
 cellobiohydrolase (Cbh1) (Cel7A) 3.2.1.176 Trichoderma koningii G-39 CAA49596.1 P00725
P62695
 
 endo-β-1,4-glucanase I (Egl1;EglI;TlCel7A;eCEL;E-CELTR) (Cel7A) 3.2.1.4 Trichoderma longibrachiatum CECT 2606 CAA43059.1
1920181A
Q12714  
 endoglucanase I (HpCel7B) (Cel7B) 3.2.1.4 Trichoderma pseudokoningii ABM90986.1 A2TDD6  
 cellobiohydrolase I / chitosanase (CBHI;Cbh1;CBH-I;TrCel7A;HjCel7A;TreCel7A) (Cel7A) 3.2.1.176
3.2.1.132
Trichoderma reesei CAH10320.1
AAE25072.1
AAR60512.1
CAF32516.1
CAF32517.1
CAF32518.1
CAR96030.1
P62694 1CEL[A,B]
1DY4[A]
1EGN[A]
1Q2B[A]
1Q2E[A,B]
2CEL[A,B]
2V3I[A]
3CEL[A]
4C4C[A]
4C4D[A]
4CEL[A,B]
4D5I[A]
4D5J[A]
4D5O[A]
4D5P[A]
4D5Q[A]
4D5V[A]
4P1H[A]
4P1J[A]
4UWT[A]
4V0Z[A]
5CEL[A]
5OA5[A,B]
5TC9[A]
6CEL[A]
7CEL[A]
8CEL[nd]
 endo-β-1,4-glucanase I (EGI;Egl1;EG-I;TrCel7B) (Cel7B) 3.2.1.4 Trichoderma reesei AAA34212.1
AAE25071.1
AAQ24882.1
AAR60514.1
ABE22093.1
CAR96034.1
CAR96035.1
P07981 1EG1[A,C]
 endo-β-1,4-glucanase (Egl1) 3.2.1.4 Trichoderma reesei PTCC 5142 AAX28897.1 Q5BMS5  
 endoglucanase I (EgI;EGI) 3.2.1.4 Trichoderma sp. SSL ACH68455.1 B5M4A3  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Trichoderma virens UKM-1 ACF93800.1 B5ATG1  
 cellobiohydrolase I / chitosanase (CBH1) 3.2.1.176
3.2.1.132
Trichoderma viride CAA37878.1 P19355  
 endo-β-1,4-glucanase I (EGI;BglI) 3.2.1.4 Trichoderma viride AS 3.3711 AAQ21382.1 Q7Z7X3  
 cellobiohydrolase I (CbhI) 3.2.1.176 Trichoderma viride AS 3.3711 AAQ76092.1 Q6UJY1  
 endoglucanase I 3.2.1.4 Trichoderma viride HK-75   Q7M4V4  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Trichoderma viride MC300-1 BAA36215.1 P19355  
 endo-β-1,4-glucanase (RsSymEG1;RsSym EG I;RsSymEG;SM2038B11) 3.2.1.4 uncultured symbiotic protist of Reticulitermes speratus BAF57296.1 A4UWN6  
 cellobiohydrolase I (CbhI) 3.2.1.176 Volvariella volvacea V14 AAD41096.1
AAD41096.2
Q9Y895  
Top


Last update: 2017-11-06 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille