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Glycoside Hydrolase Family 63

Known Activitiesprocessing α-glucosidase (EC 3.2.1.106); α-1,3-glucosidase (EC 3.2.1.84); α-glucosidase (EC 3.2.1.20)
Mechanism Inverting
ClanGH-G
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorNot known
External resourcesInterPro; PFAM;
Statistics GenBank accession (359); Uniprot accession (167); PDB accession (6); 3D entries (3); cryst (1)
Summary
All (279) Archaea (1) Bacteria (197) Eukaryota (81) Structure (3 - 1 cryst) Characterized (11)
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 ALNC14_050190 (Alnc14c58g4341)   Albugo laibachii Nc14 CCA18876.1    
 ORF   Amblyomma maculatum AEO34443.1    
 At1g24320/F3I6.26   Arabidopsis thaliana AAC00593.1
AAP21302.1
AEE30516.1
BAE99430.1
NP_173842.1		 O48699
Q84M89		  
 α-1,2-glucosidase / α-glucosidase I (Gcs1;KNF;KNOPF;At1g67490 ) 3.2.1.106 Arabidopsis thaliana AAC18786.1
AAG52297.1
AAL17718.1
AEE34653.1
AEE34654.1
BAC43508.1
CAC34725.1
NP_176916.1
NP_176916.2		 O64796
Q8GWC8
Q940D4
Q9C5B4
Q9CAG7		  
 ORF   Ascaris suum ADY41621.1    
 FAGOS_FAFR483C   Ashbya gossypii FDAG1 AEY98167.1    
 processing α-glucosidase I 3.2.1.106 Aspergillus brasiliensis ATCC 9642 BAK64066.1    
 α-glucosidase I (Cwh41;AfCwh41) 3.2.1.106 Aspergillus fumigatus YJ-407 AAR23808.1 Q6S9W4  
 AN6606.2   Aspergillus nidulans FGSC A4 EAA58135.1 C8V143  
 An15g01420   Aspergillus niger CBS 513.88 CAL00956.1 A2R4S4  
 AO090701000141   Aspergillus oryzae RIB40 BAE61889.1    
 glycoside hydrolase family 63 protein (Bofut4_p033970.1)   Botryotinia fuckeliana CCD48755.1    
 CBG05981   Caenorhabditis briggsae CAE61977.1    
 F13H10.4c   Caenorhabditis elegans Bristol N2 CAA92954.1
CAL36499.1
CAL36500.1
CAN86588.1		 A5JYS7
Q19426		  
 α-glucosidase I (Cwh41) 3.2.1.106 Candida albicans SC5314 ABB97046.1    
 CD36_45640 (Cwh41)   Candida dubliniensis CD36 CAX42430.1 B9WGQ4  
 CAGL0A01452g   Candida glabrata CBS 138 CAG57723.1    
 CPAR2_501400   Candida parapsilosis CDC317 CCE43914.1    
 α-glucosidase I (fragment)   Cricetulus griseus BAC80205.1 Q7TNW2  
 Unknown (protein for MGC:158312)   Danio rerio AAI29198.1
CAX13029.1		 A1L1S8  
 DEHA0D13486g   Debaryomyces hansenii CBS767 CAG87171.1    
 CG1597   Drosophila melanogaster AAF48028.2
AAF48028.3
AAF48028.4
AAL29139.1
ABY20525.1
NP_572707.2		 Q95R68
Q9VZ04		  
 gcs1a   Enchytraeus japonensis BAE93517.1 Q1MX36  
 gcs1b   Enchytraeus japonensis BAE93518.1 Q1MX35  
 Ecym_1427   Eremothecium cymbalariae DBVPG#7215 AET37655.1    
 AFR483C   Eremothecium gossypii ATCC 10895 AAS53854.1
AAS53854.2		 Q752U0  
 α-glucosidase (processing) (Gcs1) 3.2.1.106 Homo sapiens AAH28337.1
AAI17251.1
AAI17253.1
BAF85242.1
BAF85408.1
CAA60683.1
CAD19636.1
NP_006293.1		 A8K938
Q13724
Q13724.5		  
 predicted protein   Hordeum vulgare subsp. vulgare BAK00788.1    
 KAFR_0F03510 (Kafr0f03510)   Kazachstania africana CBS 2517 type strain:CBS 2517 CCF58947.1    
 KLLA0E10681g   Kluyveromyces lactis NRRL Y-1140 CAG99520.1    
 KLTH0E07304g   Lachancea thermotolerans CBS 6340 CAR23360.1    
 LbrM28_V2.2400   Leishmania braziliensis CAM39770.1 A4HGS4  
 LDBPK_282350   Leishmania donovani BPK282A1 CBZ35640.1    
 LinJ28.2290   Leishmania infantum JPCM5 (MCAN/ES/98/LLM-877) CAM69456.1    
 LmjF28.2200   Leishmania major strain Friedlin CAJ05671.1 Q4Q845  
 LMXM_28_2200   Leishmania mexicana MHOM/GT/2001/U1103 CBZ28592.1    
 ORF   Leptosphaeria maculans v23.1.3 CBX90523.1 E4ZGV3  
 ORF (fragment)   Leptosphaeria maculans v23.1.3 CBX92013.1 E5R543  
 ORF (fragment)   Leptosphaeria maculans v23.1.3 CBX98860.1 E5A5G2  
 MG04045.4   Magnaporthe grisea 70-15 EAA50286.1
XP_361571.1		    
 MG09721.4   Magnaporthe grisea 70-15 EAA49730.1
XP_364876.1		    
 GNLVRS01_PISO0L02783g (Piso0_003797)   Millerozyma farinosa CBS 7064 CCE84256.1    
 GNLVRS01_PISO0K02782g (Piso0_003797)   Millerozyma farinosa CBS 7064 CCE83225.1    
 α-glucosidase I (Gcs1) 3.2.1.106 Mus musculus AAD00906.1
AAH51949.1
BAE26149.1
BAE30817.1
BAE30968.1
BAE34029.1
NP_065644.1		 Q80UM7
Q80UM7.1		  
 ORF (fragment)   Mustela putorius furo AES02089.1    
 MYCTH_2302289   Myceliophthora thermophila ATCC 42464 AEO56870.1    
 NCAS_0A01760 (Ncas0a01760)   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC66734.1    
 NDAI_0D03690 (Ndai0d03690)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD24683.1    
 NCLIV_017340   Neospora caninum Liverpool CBZ51942.1    
 NCU03657.1 (B2F7.60)   Neurospora crassa OR74A CAC18158.1
EAA31501.1
XP_322959.1		 Q9HE56  
 004-22   Oikopleura dioica AAS21415.1 Q675V1  
 Os01g0921200   Oryza sativa Japonica Group BAB86175.1
BAF07139.1		 Q8RZJ2  
 Pc20g12700   Penicillium chrysogenum Wisconsin 54-1255 CAP86599.1 B6HGL1  
 PP7435_Chr1-0530   Pichia pastoris CBS 7435 CCA36680.1    
 PAS_chr1-1_0215   Pichia pastoris GS115 CAY67585.1 C4QWG2  
 PICST_39865 (Cwh41)   Pichia stipitis CBS 6054 EAZ62766.2    
 PIIN_07955   Piriformospora indica CCA74001.1    
 unnamed protein product   Podospora anserina S mat+ CAP73192.1 B2B5W7  
 α-glucosidase (processing) 3.2.1.106 Rattus rattus AAC36477.1
NP_113937.1		 O88941.1  
 EC1118_1G1_2674g   Saccharomyces cerevisiae EC1118 Lalvin EC1118 CAY79731.1 C8Z8L5  
 α-glucosidase I (Cwh41;Gls1;YGL027c;Der7) 3.2.1.106 Saccharomyces cerevisiae S288c AAC49157.1
CAA96728.1
NP_011488.1		 P53008 cryst
 ORF (fragment)   Schistosoma japonicum AAX28489.1
AAX28489.2		 Q5BVT6  
 SJCHGC04071 (fragment)   Schistosoma japonicum AAX25720.2 Q5C3Q5  
 SJCHGC07586 (fragment)   Schistosoma japonicum AAX27824.2 Q5BXQ1  
 Smp_024580   Schistosoma mansoni CAZ30132.1
CAZ30133.1
CCD79301.1
CCD79302.1		 C4Q3Y2  
 SPAC6G10.09 (Gls1)   Schizosaccharomyces pombe 972h- CAB11295.1
NP_594106.1		 O14255.1  
 glucosidase, partial (fragment)   Silene latifolia AEL98721.1    
 glucosidase, partial (fragment)   Silene latifolia AEL98722.1    
 sr13790   Sporisorium reilianum SRZ2 CBQ73129.1    
 TPHA_0K01720 (Tpha0k01720)   Tetrapisispora phaffii CBS 4417 type strain:CBS 4417 CCE65305.1    
 THITE_2108507   Thielavia terrestris NRRL 8126 AEO63368.1    
 THITE_157561   Thielavia terrestris NRRL 8126 AEO69881.1    
 TDEL_0F02570 (Tdel0f02570)   Torulaspora delbrueckii type strain:CBS 1146 CCE93068.1    
 Unknown (protein for IMAGE:6988934)   Xenopus (Silurana) tropicalis AAI00611.1 Q497D5  
 mannosyl-oligosaccharide glucosidase (fragment)   Xenopus clivii AEP24715.1
AEP24721.1
AEP24722.1		    
 MogS (fragment)   Xenopus gilli ADT90602.1
ADT90605.1
ADT90613.1		    
 LOC100158418   Xenopus laevis AAI61695.1 B1WBB6  
 mannosyl-oligosaccharide glucosidase (fragment)   Xenopus largeni AEP24736.1
AEP24738.1
AEP24740.1
AEP24744.1
AEP24746.1
AEP24748.1
AEP24750.1		    
 YALI0F14927g   Yarrowia lipolytica CLIB122 CLIB99 CAG78244.1    
 YALI0F14927p   Yarrowia lipolytica W29 XP_505435.1    
 ZYRO0G09702g   Zygosaccharomyces rouxii CBS 732 CAR29480.1    




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