Activities in Family	processing α-glucosidase (EC 3.2.1.106); α-1,3-glucosidase (EC 3.2.1.84); α-glucosidase (EC 3.2.1.20); mannosylglycerate α-mannosidase / mannosylglycerate hydrolase (EC 3.2.1.170)
Mechanism	Inverting
Clan	GH-G
3D Structure Status	( α / α ) 6
Catalytic Nucleophile/Base	Glu (inferred)
Catalytic Proton Donor	Asp (inferred)
Statistics	GenBank accession (2745); Uniprot accession (205); PDB accession (32); 3D entries (5); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
GCS1, partial (fragment)		Ablennes hians	AKE13517.1
ORF (fragment)		Achirus lineatus	AGD95979.1
secreted protein		Achlya hypogyna ATCC 48635	AIG56123.1
ALNC14_050190 (Alnc14c58g4341)		Albugo laibachii Nc14	CCA18876.1
ORF (fragment)		Alectis ciliaris	AGD95942.1
GCS1, partial (fragment)		Alepidomus evermanni	AKE13518.1
ORF (fragment)		Ambassis interrupta	AGD95867.1
ORF (fragment)		Amblycirrhitus pinos	AGD95877.1
ORF		Amblyomma maculatum	AEO34443.1
ORF (fragment)		Ammodytes hexapterus	AGD95925.1
ORF (fragment)		Ancylopsetta ommata	AGD95994.1
ORF (fragment)		Antigonia capros	AGD95914.1
ORF (fragment)		Apogonidae sp. FMNH119726	AGD95969.1
At1g24320/F3I6.26		Arabidopsis thaliana	NP_173842.1 AAC00593.1 AAP21302.1 AEE30516.1 ANM59279.1 BAE99430.1	O48699 Q84M89
α-1,2-glucosidase / α-glucosidase I (Gcs1;KNF;KNOPF;At1g67490 )	3.2.1.106	Arabidopsis thaliana	NP_176916.2 AAC18786.1 AAG52297.1 AAL17718.1 AEE34653.1 AEE34654.1 BAC43508.1 CAC34725.1 NP_176916.1	F4HTM3 O64796 Q8GWC8 Q940D4 Q9C5B4 Q9CAG7
ORF (fragment)		Arnoglossus imperialis	AGD95983.1
ORF (fragment)		Arnoglossus imperialis	AGD96032.1
EGX50243.1		Arthrobotrys oligospora ATCC 24927	EGX50243.1
ORF		Ascaris suum	ADY41621.1
ORF (fragment)		Aseraggodes heemstrai	AGD96028.1
ORF (fragment)		Aseraggodes kobensis	AGD96026.1
processing α-glucosidase I	3.2.1.106	Aspergillus brasiliensis ATCC 9642 (formerly Aspergillus niger ATCC 9642)	BAK64066.1
α-glucosidase I (Cwh41;AfCwh41)	3.2.1.106	Aspergillus fumigatus YJ-407	AAR23808.1	Q6S9W4
AN6606.2 (fragment)		Aspergillus nidulans FGSC A4	EAA58135.1	C8V143 Q5AYM4
An15g01420		Aspergillus niger CBS 513.88	CAL00956.1	A2R4S4
AO090701000141		Aspergillus oryzae RIB40	BAE61889.1	Q2U976
ORF (fragment)		Asterorhombus fijiensis	AGD95984.1
ORF (fragment)		Atheresthes evermanni	AGD96002.1
GCS1, partial (fragment)		Atherina boyeri	AKE13519.1
GCS1, partial (fragment)		Atherina breviceps	AKE13520.1
GCS1, partial (fragment)		Atherina presbyter	AKE13521.1
GCS1, partial (fragment)		Atherinella argentea	AKE13522.1
GCS1, partial (fragment)		Atherinella balsana	AKE13523.1
GCS1, partial (fragment)		Atherinella blackburni	AKE13524.1
GCS1, partial (fragment)		Atherinella brasiliensis	AKE13525.1
GCS1, partial (fragment)		Atherinella crystallina	AKE13526.1
GCS1, partial (fragment)		Atherinella guatemalensis	AKE13527.1
GCS1, partial (fragment)		Atherinella hubbsi	AKE13528.1
GCS1, partial (fragment)		Atherinella marvelae	AKE13529.1
GCS1, partial (fragment)		Atherinella milleri	AKE13530.1
GCS1, partial (fragment)		Atherinella panamensis	AKE13531.1
GCS1, partial (fragment)		Atherinella pellosemeion	AKE13532.1
GCS1, partial (fragment)		Atherinella sallei	AKE13533.1
GCS1, partial (fragment)		Atherinella sardina	AKE13534.1
GCS1, partial (fragment)		Atherinella serrivomer	AKE13535.1
GCS1, partial (fragment)		Atherinella starksi	AKE13536.1
GCS1, partial (fragment)		Atherinomorus lacunosus	AKE13537.1
GCS1, partial (fragment)		Atherinomorus stipes	AKE13539.1
GCS1, partial (fragment)		Atherinomorus vaigiensis	AKE13538.1
GCS1, partial (fragment)		Atherinops affinis	AKE13540.1
GCS1, partial (fragment)		Atherinopsis californiensis	AKE13541.1
GCS1, partial (fragment)		Atherion elymus	AKE13542.1
ORF (fragment)		Atule mate	AGD95943.1
GCS1, partial (fragment)		Austrolebias arachan	AKE13543.1
GCS1, partial (fragment)		Basilichthys australis	AKE13544.1
GCS1, partial (fragment)		Basilichthys microlepidotus	AKE13545.1
GCS1, partial (fragment)		Basilichthys semotilus	AKE13546.1
GCS1, partial (fragment)		Bedotia marojejy	AKE13547.1
GCS1, partial (fragment)		Bedotia sp. Ankavia	AKE13548.1
GCS1, partial (fragment)		Bedotia sp. Namorona	AKE13549.1
ORF (fragment)		Blenniella cyanostigma	AGD95912.1
ORF (fragment)		Bothus lunatus	AGD95985.1
ORF (fragment)		Bothus robinsi	AGD95986.1
BCIN_16g01950 (Bccwh41)		Botrytis cinerea B05.10	ATZ58403.1
glycoside hydrolase family 63 protein (Bofut4_p033970.1)		Botrytis cinerea T4	CCD48755.1
ORF (fragment)		Brachirus annularis	AGD96044.1
ORF (fragment)		Brama brama	AGD95868.1
BOLC6T38956H		Brassica oleracea	VDD63503.1
BOLC7T42308H		Brassica oleracea	VDD36748.1
BOLC5T29329H		Brassica oleracea	VDD41782.1
BRAA10T42875Z (fragment)		Brassica rapa	VDD17162.1
BRAA07T30877Z		Brassica rapa	VDD01141.1
CBG05981		Caenorhabditis briggsae	CAE61977.1
α-glucosidase I (Agl-1;F13H10.4c)	3.2.1.106	Caenorhabditis elegans Bristol N2	CAN86588.1 CAA92954.1 CAL36499.1 CAL36500.1	A5JYS7 Q19426
ORF (fragment)		Caesio caerulaurea	AGD95869.1
GCS1, partial (fragment)		Cairnsichthys rhombosomoides	AKE13550.1
ORF (fragment)		Callionymus sp. KU 7248	AGD95913.1
ORF (fragment)		Callorhinchus milii	AFO99221.1
ORF (fragment)		Callorhinchus milii	AFO98427.1
CAALFM_C406100WA (Cwh41)		Candida albicans SC5314	AOW29337.1
α-glucosidase I (Cwh41;CaCWH41)	3.2.1.106	Candida albicans SC5314	ABB97046.1
CD36_45640 (Cwh41)		Candida dubliniensis CD36	CAX42430.1	B9WGQ4
CAGL0A01452g		[Candida] glabrata CBS 138	CAG57723.1	Q6FXZ2
SAMEA4029010_CIC11G00000000941		[Candida] intermedia CBS 141442	SGZ53813.1
SAMEA4029009_CIC11G00000001449		[Candida] intermedia PYCC 4715	SGZ53584.1
CORT_0B01540		Candida orthopsilosis Co 90-125	CCG21873.1
CPAR2_501400		Candida parapsilosis CDC317	CCE43914.1
ORF (fragment)		Carangoides ferdau	AGD95871.1
ORF (fragment)		Carangoides plagiotaenia	AGD95944.1
ORF (fragment)		Carangoides ruber	AGD95870.1
ORF (fragment)		Caranx ignobilis	AGD95945.1
ORF (fragment)		Caranx sexfasciatus	AGD95951.1
ORF (fragment)		Caristius sp. KU 6500	AGD95872.1
ORF (fragment)		Centropomus ensiferus	AGD95964.1
ORF (fragment)		Centropomus medius	AGD95975.1
ORF (fragment)		Centropomus undecimalis	AGD95874.1
ORF (fragment)		Centropomus viridis	AGD95966.1
ORF (fragment)		Centropomus viridis	AGD95970.1
ORF (fragment)		Chaetodon auriga	AGD95875.1
ORF (fragment)		Channa striata	AGD95915.1
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