Glycoside Hydrolase Family 63

Activities in Familyprocessing α-glucosidase (EC 3.2.1.106); α-1,3-glucosidase (EC 3.2.1.84); α-glucosidase (EC 3.2.1.20); mannosylglycerate α-mannosidase / mannosylglycerate hydrolase (EC 3.2.1.170)
Mechanism Inverting
ClanGH-G
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorAsp (inferred)
Statistics GenBank accession (2074); Uniprot accession (205); PDB accession (18); 3D entries (3); cryst (0)
All (1822) Archaea (3) Bacteria (1291) Eukaryota (528) Structure (3) Characterized (19)
| 1 | 2 | 3 | 4 | 5 | 6 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GCS1, partial (fragment)   Ablennes hians AKE13517.1    
 ORF (fragment)   Achirus lineatus AGD95979.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56123.1    
 ALNC14_050190 (Alnc14c58g4341)   Albugo laibachii Nc14 CCA18876.1    
 ORF (fragment)   Alectis ciliaris AGD95942.1    
 GCS1, partial (fragment)   Alepidomus evermanni AKE13518.1    
 ORF (fragment)   Ambassis interrupta AGD95867.1    
 ORF (fragment)   Amblycirrhitus pinos AGD95877.1    
 ORF   Amblyomma maculatum AEO34443.1    
 ORF (fragment)   Ammodytes hexapterus AGD95925.1    
 ORF (fragment)   Ancylopsetta ommata AGD95994.1    
 ORF (fragment)   Antigonia capros AGD95914.1    
 ORF (fragment)   Apogonidae sp. FMNH119726 AGD95969.1    
 At1g24320/F3I6.26   Arabidopsis thaliana NP_173842.1
AAC00593.1
AAP21302.1
AEE30516.1
ANM59279.1
BAE99430.1
O48699
Q84M89
 
 α-1,2-glucosidase / α-glucosidase I (Gcs1;KNF;KNOPF;At1g67490 ) 3.2.1.106 Arabidopsis thaliana NP_176916.2
AAC18786.1
AAG52297.1
AAL17718.1
AEE34653.1
AEE34654.1
BAC43508.1
CAC34725.1
NP_176916.1
F4HTM3
O64796
Q8GWC8
Q940D4
Q9C5B4
Q9CAG7
 
 ORF (fragment)   Arnoglossus imperialis AGD95983.1    
 ORF (fragment)   Arnoglossus imperialis AGD96032.1    
 EGX50243.1   Arthrobotrys oligospora ATCC 24927 EGX50243.1    
 ORF   Ascaris suum ADY41621.1    
 ORF (fragment)   Aseraggodes heemstrai AGD96028.1    
 ORF (fragment)   Aseraggodes kobensis AGD96026.1    
 processing α-glucosidase I 3.2.1.106 Aspergillus brasiliensis ATCC 9642 (formerly Aspergillus niger ATCC 9642) BAK64066.1    
 α-glucosidase I (Cwh41;AfCwh41) 3.2.1.106 Aspergillus fumigatus YJ-407 AAR23808.1 Q6S9W4  
 AN6606.2 (fragment)   Aspergillus nidulans FGSC A4 EAA58135.1 C8V143
Q5AYM4
 
 An15g01420   Aspergillus niger CBS 513.88 CAL00956.1 A2R4S4  
 AO090701000141   Aspergillus oryzae RIB40 BAE61889.1 Q2U976  
 ORF (fragment)   Asterorhombus fijiensis AGD95984.1    
 ORF (fragment)   Atheresthes evermanni AGD96002.1    
 GCS1, partial (fragment)   Atherina boyeri AKE13519.1    
 GCS1, partial (fragment)   Atherina breviceps AKE13520.1    
 GCS1, partial (fragment)   Atherina presbyter AKE13521.1    
 GCS1, partial (fragment)   Atherinella argentea AKE13522.1    
 GCS1, partial (fragment)   Atherinella balsana AKE13523.1    
 GCS1, partial (fragment)   Atherinella blackburni AKE13524.1    
 GCS1, partial (fragment)   Atherinella brasiliensis AKE13525.1    
 GCS1, partial (fragment)   Atherinella crystallina AKE13526.1    
 GCS1, partial (fragment)   Atherinella guatemalensis AKE13527.1    
 GCS1, partial (fragment)   Atherinella hubbsi AKE13528.1    
 GCS1, partial (fragment)   Atherinella marvelae AKE13529.1    
 GCS1, partial (fragment)   Atherinella milleri AKE13530.1    
 GCS1, partial (fragment)   Atherinella panamensis AKE13531.1    
 GCS1, partial (fragment)   Atherinella pellosemeion AKE13532.1    
 GCS1, partial (fragment)   Atherinella sallei AKE13533.1    
 GCS1, partial (fragment)   Atherinella sardina AKE13534.1    
 GCS1, partial (fragment)   Atherinella serrivomer AKE13535.1    
 GCS1, partial (fragment)   Atherinella starksi AKE13536.1    
 GCS1, partial (fragment)   Atherinomorus lacunosus AKE13537.1    
 GCS1, partial (fragment)   Atherinomorus stipes AKE13539.1    
 GCS1, partial (fragment)   Atherinomorus vaigiensis AKE13538.1    
 GCS1, partial (fragment)   Atherinops affinis AKE13540.1    
 GCS1, partial (fragment)   Atherinopsis californiensis AKE13541.1    
 GCS1, partial (fragment)   Atherion elymus AKE13542.1    
 ORF (fragment)   Atule mate AGD95943.1    
 GCS1, partial (fragment)   Austrolebias arachan AKE13543.1    
 GCS1, partial (fragment)   Basilichthys australis AKE13544.1    
 GCS1, partial (fragment)   Basilichthys microlepidotus AKE13545.1    
 GCS1, partial (fragment)   Basilichthys semotilus AKE13546.1    
 GCS1, partial (fragment)   Bedotia marojejy AKE13547.1    
 GCS1, partial (fragment)   Bedotia sp. Ankavia AKE13548.1    
 GCS1, partial (fragment)   Bedotia sp. Namorona AKE13549.1    
 ORF (fragment)   Blenniella cyanostigma AGD95912.1    
 ORF (fragment)   Bothus lunatus AGD95985.1    
 ORF (fragment)   Bothus robinsi AGD95986.1    
 glycoside hydrolase family 63 protein (Bofut4_p033970.1)   Botrytis cinerea T4 CCD48755.1    
 ORF (fragment)   Brachirus annularis AGD96044.1    
 ORF (fragment)   Brama brama AGD95868.1    
 CBG05981   Caenorhabditis briggsae CAE61977.1    
 α-glucosidase I (Agl-1;F13H10.4c) 3.2.1.106 Caenorhabditis elegans Bristol N2 CAN86588.1
CAA92954.1
CAL36499.1
CAL36500.1
A5JYS7
Q19426
 
 ORF (fragment)   Caesio caerulaurea AGD95869.1    
 GCS1, partial (fragment)   Cairnsichthys rhombosomoides AKE13550.1    
 ORF (fragment)   Callionymus sp. KU 7248 AGD95913.1    
 ORF (fragment)   Callorhinchus milii AFO99221.1    
 ORF (fragment)   Callorhinchus milii AFO98427.1    
 CAALFM_C406100WA (Cwh41)   Candida albicans SC5314 AOW29337.1    
 α-glucosidase I (Cwh41;CaCWH41) 3.2.1.106 Candida albicans SC5314 ABB97046.1    
 CD36_45640 (Cwh41)   Candida dubliniensis CD36 CAX42430.1 B9WGQ4  
 CAGL0A01452g   Candida glabrata CBS 138 CAG57723.1 Q6FXZ2  
 SAMEA4029010_CIC11G00000000941   [Candida] intermedia CBS 141442 SGZ53813.1    
 SAMEA4029009_CIC11G00000001449   [Candida] intermedia PYCC 4715 SGZ53584.1    
 CORT_0B01540   Candida orthopsilosis Co 90-125 CCG21873.1    
 CPAR2_501400   Candida parapsilosis CDC317 CCE43914.1    
 ORF (fragment)   Carangoides ferdau AGD95871.1    
 ORF (fragment)   Carangoides plagiotaenia AGD95944.1    
 ORF (fragment)   Carangoides ruber AGD95870.1    
 ORF (fragment)   Caranx ignobilis AGD95945.1    
 ORF (fragment)   Caranx sexfasciatus AGD95951.1    
 ORF (fragment)   Caristius sp. KU 6500 AGD95872.1    
 ORF (fragment)   Centropomus ensiferus AGD95964.1    
 ORF (fragment)   Centropomus medius AGD95975.1    
 ORF (fragment)   Centropomus undecimalis AGD95874.1    
 ORF (fragment)   Centropomus viridis AGD95966.1    
 ORF (fragment)   Centropomus viridis AGD95970.1    
 ORF (fragment)   Chaetodon auriga AGD95875.1    
 ORF (fragment)   Channa striata AGD95915.1    
 ORF (fragment)   Chascanopsetta lugubris AGD96043.1    
 ORF (fragment)   Cheilodactylus fasciatus AGD95876.1    
 GCS1, partial (fragment)   Chirostoma labarcae AKE13551.1    
 GCS1, partial (fragment)   Chirostoma riojai AKE13552.1    
 ORF (fragment)   Chloroscombrus chrysurus AGD95946.1    
 ORF (fragment)   Citharichthys sordidus AGD95995.1    
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