Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2130); Uniprot accession (61); PDB accession (35); 3D entries (9); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H21	QHX41689.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H26	QHX41690.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H27	QHX41691.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H28	QHX41692.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H29	QHX41693.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H30	QHX41694.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum H31	QHX41695.1			5
CFM90_21880		Ralstonia solanacearum HA4-1	AZU58840.1 ALB08680.1			5
Egl (fragment)		Ralstonia solanacearum HAIP101	BAH79074.1			5
endo-1,4-β-glucanase, partial (EgL) (fragment)		Ralstonia solanacearum Haricot1	ARS24968.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBBD1	AKI32290.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBBD2	ALB08681.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBBD3	AKI32291.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBBD4	AKI32292.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBES1	AKI32293.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBES2	AKI32294.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBES3	AKI32295.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBES4	AKI32296.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBES5	AKI32297.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBES6	AKI32298.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBESBD-1	ALP82180.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBESHF-1	ALP82179.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBESXF-1	ALP82181.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBESXF-2	ALP82182.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBHF1	AKI32299.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBHF2	AKI32300.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBJS1	ALB08682.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBJS2	AKI32301.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBJS3	AKI32302.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBJS4	AKI32303.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLC1	AKI32304.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLC2	AKI32305.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLC3	AKI32306.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLC4	AKI32307.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLC5	ALB08683.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLC6	AKI32308.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLF1	ALB08684.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBLF2	AKI32309.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBSYFX1	AKI32310.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBSYFX2	ALB08685.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBSYFX3	AKI32311.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBSYFX4	AKI32312.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE1	AKI32313.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE10	AKI32321.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE11	AKI32322.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE12	AKI32323.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE2	AKI32314.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE3	AKI32315.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE4	ALB08686.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE5	AKI32316.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE6	AKI32317.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE7	AKI32318.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE8	AKI32319.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXE9	AKI32320.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXEJY1	AKI32324.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXEJY2	AKI32325.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXEJY3	AKI32326.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXEJY4	AKI32327.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF1	AKI32328.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF2	AKI32329.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF3	AKI32330.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF4	AKI32331.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF5	AKI32332.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF6	AKI32333.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF7	AKI32334.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXF8	AKI32335.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXFDJ1	AKI32336.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HBXFDJ2	AKI32337.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum HD-3	AVP27650.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum HD-5	AVP27651.1			5
endo-1,4-β-glucanase, partial (EgL) (fragment)		Ralstonia solanacearum HGT1	ARS24959.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum HN1-2A	QKI35588.1			5
endoglucanase (Egl) (fragment)		Ralstonia solanacearum HN523	ADV35921.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNCZGY-1	ALP82123.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH1	ALB08687.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH2	ALB08688.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH3	ALB08689.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH4	ALB08690.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH5	ALB08691.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH6	ALB08692.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNFH7	ALB08693.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNXXFH-1	ALP82212.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNZMD-1	ALP82175.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNZMD1	ALB08694.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNZMD2	ALB08695.1			5
endoglucanase precursor, partial (EgL) (fragment)		Ralstonia solanacearum HNZMD3	ALB08696.1			5
endoglucanase, partial (EgL) (fragment)		Ralstonia solanacearum HP-1	AVP27679.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP11-1	BBJ06309.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP11-2	BBJ06310.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP15-1	BBJ06312.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP15-2	BBJ06313.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP17-1	BBJ06316.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP17-2	BBJ06317.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP2-1	BBJ06307.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP2-2	BBJ06308.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP4-2	BBJ06311.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP7-1	BBJ06314.1			5
endoglucanase, partial (fragment)		Ralstonia solanacearum HP7-2	BBJ06315.1			5
endo-1,4-β-glucanase, partial (EgL) (fragment)		Ralstonia solanacearum HRA1	ARS24964.1			5
endo-1,4-β-glucanase, partial (EgL) (fragment)		Ralstonia solanacearum HRGP1	ARS24963.1			5
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