Glycoside Hydrolase Family 5 / Subf 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (3516); Uniprot accession (276); PDB accession (20); 3D entries (9); cryst (0)
All (3119) Bacteria (2943) Eukaryota (174) unclassified (2) Structure (9) Characterized (60)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 30 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 A0U92_11525   Acetobacter aceti TMW2.1153 AQS85316.1     5
 Arad_0393 (EgL)   Agrobacterium radiobacter K84 ACM25096.1 B9J6Z0   5
 BSY240_3431 (fragment)   Agrobacterium sp. RAC06 AOG10505.1     5
 Avi_6012   Agrobacterium vitis S4 ACM39029.1 B9K2D1   5
 dqs_2369   Azoarcus olearius DQS4 ANQ85400.1     5
 endoglucanase (Egl;EglA;azo2236) 3.2.1.4 Azoarcus sp. BH72 ABB92850.1
CAL94853.1
A0S6A6   5
 Bovatus_03051 (Egl_1)   Bacteroides ovatus ATCC 8483 ALJ47659.1     5
 Bovatus_03053 (Egl_2)   Bacteroides ovatus ATCC 8483 ALJ47661.1     5
 BACOV975_00815   Bacteroides ovatus V975 SCV07059.1     5
 BACOV975_00813   Bacteroides ovatus V975 SCV07057.1     5
 BXY_21130   Bacteroides xylanisolvens XB1A CBK67191.1 D6CYD9   5
 BXY_21150   Bacteroides xylanisolvens XB1A CBK67193.1 D6CYE1   5
 B0B51_10750   blood disease bacterium A2-HR MARDI AQW31539.1     5
 endoglucanase (fragment)   blood disease bacterium R223 AAY33899.1 Q4U4W3   5
 BDB_120007 (EgL)   blood disease bacterium R229 CCA80961.1     5
 Egl (fragment)   blood disease bacterium R229 MAFF301552 ADD24725.1 D3XCB3   5
 endoglucanase (fragment)   blood disease bacterium R233 AAY33903.1 Q4U4V9   5
 endoglucanase (fragment)   blood disease bacterium R506 AAY33900.1 Q4U4W2   5
 endoglucanase (fragment)   blood disease bacterium T520 AAS46799.1 Q5DSS9   5
 endoglucanase (fragment)   blood disease bacterium T633 AAS46800.1 Q5DSS8   5
 endoglucanase (fragment)   blood disease bacterium Y1 AAY33917.1 Q4U4U5   5
 CJA_0619 (5H) (Cel5H)   Cellvibrio japonicus Ueda107 ACE83988.1 B3PJL3   5
 CBR65_10395   Cellvibrio sp. PSBB006 ARU27801.1     5
 B0D95_08980   Cellvibrio sp. PSBB023 AQT62352.1     5
 LT85_2938   Collimonas arenae Cal35 AIY42096.1     5
 CAter10_3262   Collimonas arenae Ter10 AMP00796.1     5
 CAter282_2968   Collimonas arenae Ter282 AMP10689.1     5
 CFU_2730 (EgL)   Collimonas fungivorans Ter331 AEK62557.1     5
 CFter6_3440   Collimonas fungivorans Ter6 AMO96073.1     5
 CPter291_1900 (EgL)   Collimonas pratensis Ter291 AMP14166.1     5
 CPter91_1873 (EgL)   Collimonas pratensis Ter91 AMP04246.1     5
 CYFUS_009190   Cystobacter fuscus DSM 52655 ATB43710.1     5
 Echvi_0403   Echinicola vietnamensis DSM 17526 AGA76691.1     5
 GDI2537   Gluconacetobacter diazotrophicus PA1 5 CAP56480.1
ACI50569.1
A9HNP5   5
 YC6258_03757   Gynuella sunshinyii YC6258 AJQ95793.1     5
 HYPMC_1763   Hyphomicrobium sp. MC1 CCB64988.1     5
 HYPMC_4921   Hyphomicrobium sp. MC1 CCB68129.1     5
 CNX70_08570   Janthinobacterium svalbardensis PAMC 27463 ATD60239.1     5
 S101446_03139   Komagataeibacter europaeus SRCM101446 ARW18214.1     5
 GLX_27720   Komagataeibacter medellinensis NBRC 3288 BAK85184.1     5
 B0W47_14400   Komagataeibacter nataicola RZS01 AQU88449.1     5
 KRIGEM_00957 (EgL)   Komagataeibacter rhaeticus iGEM SAY48012.1     5
 H845_813   Komagataeibacter xylinus E25 AHI24765.1     5
 A0U89_05145   Kozakia baliensis DSM 14400 AOX18139.1     5
 A0U90_06745   Kozakia baliensis NBRC 16680 AOX21253.1     5
 AKJ09_04855   Labilithrix luteola DSM 27648 AKU98191.1     5
 AKJ09_07481   Labilithrix luteola DSM 27648 AKV00818.1     5
 AKJ09_04396   Labilithrix luteola DSM 27648 AKU97732.1     5
 Cel5A (fragment)   Martelella endophytica YC6887 AHY20451.1
AJY45818.1
    5
 endoglucanase (Cel5D) 3.2.1.4 Martelella mediterranea WP_018063499.1     5
 Mame_00070 (EgL)   Martelella mediterranea DSM 17316 MACL11 AQZ49454.1     5
 AZF01_02365   Martelella sp. AD-3 AMM83348.1     5
 MEBOL_003338   Melittangium boletus DSM 14713 ATB29883.1     5
 Maq22A_1p38150 (BglC)   Methylobacterium aquaticum MA-22A BAQ49793.1     5
 M446_1066   Methylobacterium sp. 4-46 ACA15596.1 B0UDB0   5
 M446_1077   Methylobacterium sp. 4-46 ACA15606.1 B0UDC0   5
 M446_1513   Methylobacterium sp. 4-46 ACA16017.1 B0UL20   5
 M446_3420   Methylobacterium sp. 4-46 ACA17809.1 B0U8N9   5
 GL4_0204   Methyloceanibacter caenitepidi Gela4 BAQ15674.1     5
 APZ00_04210   Pannonibacter phragmitetus 31801 ALV26380.1     5
 SL003B_3916   Polymorphum gilvum SL003B-26A1 ADZ72336.1     5
 CL52_07500   Pseudomonas balearica DSM 6083 AJE14898.1     5
 CL52_13220   Pseudomonas balearica DSM 6083 AJE15949.1     5
 Psefu_3857   Pseudomonas fulva 12-X AEF23813.1     5
 APT59_17720   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ85949.1     5
 APT59_20935   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ86553.1     5
 APT59_20260   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ86424.1     5
 APT59_09030   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ84341.1     5
 APT59_08520   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ84247.1     5
 APT59_08520   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ84247.1     5
 APT59_01370   Pseudomonas oryzihabitans USDA-ARS-USMARC-56511 ALZ82920.1     5
 BJP27_12225   Pseudomonas psychrotolerans PRS08-11306 APQ12228.1     5
 BJP27_00300   Pseudomonas psychrotolerans PRS08-11306 APQ10037.1     5
 BJP27_09460   Pseudomonas psychrotolerans PRS08-11306 APQ11720.1     5
 BJP27_15540   Pseudomonas psychrotolerans PRS08-11306 APQ12847.1     5
 BJP27_23475   Pseudomonas psychrotolerans PRS08-11306 APQ14298.1     5
 BJP27_23475   Pseudomonas psychrotolerans PRS08-11306 APQ14298.1     5
 LT40_08580   Pseudomonas rhizosphaerae DSM 16299 AIS17452.1     5
 endoglucanase (CelX) (Cel5M) 3.2.1.4 Pseudomonas sp. MM15 AEM45646.1     5
 MT1_1476   Pseudomonas sp. MT-1 BAP78654.1     5
 MT1_2338   Pseudomonas sp. MT-1 BAP79516.1     5
 MT1_2826   Pseudomonas sp. MT-1 BAP80001.1     5
 MT1_3394   Pseudomonas sp. MT-1 BAP80569.1     5
 MT1_3399   Pseudomonas sp. MT-1 BAP80574.1     5
 UIB01_08740   Pseudomonas stutzeri 19SMN4 AHY42565.1     5
 UIB01_14810   Pseudomonas stutzeri 19SMN4 AHY43679.1     5
 PS273GM_15345   Pseudomonas stutzeri 273 ANF26427.1     5
 PS273GM_17735   Pseudomonas stutzeri 273 ANF26849.1     5
 PS273GM_15370   Pseudomonas stutzeri 273 ANF26431.1     5
 PS273GM_20165   Pseudomonas stutzeri 273 ANF27282.1     5
 PS273GM_01645   Pseudomonas stutzeri 273 ANF23937.1     5
 CH92_06090   Pseudomonas stutzeri 28a24 AHL74691.1     5
 CH92_06115   Pseudomonas stutzeri 28a24 AHL74695.1     5
 CH92_10825   Pseudomonas stutzeri 28a24 AHL75570.1     5
 CH92_12725   Pseudomonas stutzeri 28a24 AHL75913.1     5
 CH92_15920   Pseudomonas stutzeri 28a24 AHL76500.1     5
 PST_1459   Pseudomonas stutzeri A1501 ABP79150.1 A4VJJ9   5
 PST_2494 (Orf1)   Pseudomonas stutzeri A1501 ABP80146.1 A4VME5 4LX4[A,B,C,D] 5
 PSTAB_2394   Pseudomonas stutzeri ATCC 17588 = LMG 11199 AEJ05675.1     5
 PSTAB_1391   Pseudomonas stutzeri ATCC 17588 = LMG 11199 AEJ04672.1     5
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