Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2125); Uniprot accession (61); PDB accession (35); 3D entries (9); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
IAD21_04620 (EgL)		Abditibacteriota bacterium IAD-21	BCM92738.1			5
AAJCM20276_12050 (EgL) (fragment)		Acetobacter aceti JCM20276	BCI66581.1			5
EMQ_1124 (EgL)		Acetobacter aceti NBRC 14818	BCK75518.1			5
A0U92_11525		Acetobacter aceti TMW2.1153	AQS85316.1			5
HN018_01005		Acetobacteraceae bacterium PAMC 26569	QKE88818.1			5
HN018_13605		Acetobacteraceae bacterium PAMC 26569	QKE90937.1			5
HN018_13630		Acetobacteraceae bacterium PAMC 26569	QKE90941.1			5
HN018_13595		Acetobacteraceae bacterium PAMC 26569	QKE90936.1			5
OJY61_17790		Aeromonas caviae SVJ23	UZC85672.1			5
E4184_09080		Aeromonas media T0.1-19	QJT21565.1			5
IBG34_04165		Aeromonas media T5-1	QYK82140.1			5
FE240_12870		Aeromonas simiae A6	QFI55500.1			5
KW556_02935		Aeromonas veronii HD6454	UWH28716.1			5
GH983_17040		Agrobacterium sp. MA01	QGG92074.1			5
BSY240_3431 (fragment)		Agrobacterium sp. RAC06	AOG10505.1			5
AVCG412_13330		Agrobacterium vitis CG412	UJL73716.1			5
AVCG678_13475		Agrobacterium vitis CG678	UJL78417.1			5
AVCG78_13475		Agrobacterium vitis CG78	UJL83628.1			5
V6582_13210		Agrobacterium vitis CG957	WWS78569.1			5
K4831_14705		Agrobacterium vitis F2/5	QZO03647.1			5
AVF2S5_13050		Agrobacterium vitis F2/5	UJL88771.1			5
G6L01_014090		Agrobacterium vitis T60/94	WEO71098.1			5
RvVAR031_32200 (EgL)		Agrobacterium vitis VAR03-1	BCH55610.1			5
RvVAR0630_08070 (EgL)		Agrobacterium vitis VAR06-30	BCH58183.1			5
RvVAT039_12290 (EgL)		Agrobacterium vitis VAT03-9	BCH64013.1			5
Avi_6012		Allorhizobium ampelinum S4	ACM39029.1			5
F0U60_15620		Archangium minus Cbm 6	WNG45371.1			5
F0U61_15525		Archangium violaceum Cbvi 34	WNG34902.1			5
JQX13_05705		Archangium violaceum SDU34	QRK09627.1			5
pbN1_39100 (EglA)		Aromatoleum bremense PbN1	QTQ33893.1			5
Q31a_15560 (EgL)		Aureliella helgolandensis Q31a	QDV23258.1			5
dqs_2369		Azoarcus olearius DQS4	ANQ85400.1			5
endoglucanase (Egl;EglA;azo2236)	3.2.1.4	Azoarcus sp. BH72	ABB92850.1 CAL94853.1	A0S6A6		5
CJ010_14195		Azoarcus sp. DD4	QDF99748.1			5
KQP55_02270		Bacteroides nordii WAL7935	UYU49454.1			5
KQP55_02235		Bacteroides nordii WAL7935	UYU49447.1			5
DYI28_17325		Bacteroides ovatus 3725 D1 iv	QDM10315.1			5
DYI28_17335		Bacteroides ovatus 3725 D1 iv	QDM10317.1			5
Bovatus_03051 (Egl_1)		Bacteroides ovatus ATCC 8483	ALJ47659.1			5
Bovatus_03053 (Egl_2)		Bacteroides ovatus ATCC 8483	ALJ47661.1			5
NQ517_04055		Bacteroides ovatus ATCC 8483	UWN92813.1			5
NQ517_04045		Bacteroides ovatus ATCC 8483	UWN92811.1			5
NXW74_04635		Bacteroides ovatus BFG-126	UVR10326.1			5
NXW74_04655		Bacteroides ovatus BFG-126	UVR10330.1			5
NXW64_04755 (fragment)		Bacteroides ovatus BFG-177	UVO70403.1			5
NXW64_04730		Bacteroides ovatus BFG-177	UVO70398.1			5
NXV93_04490		Bacteroides ovatus BFG-224	UVR44281.1			5
NXV93_04500		Bacteroides ovatus BFG-224	UVR44283.1			5
NXV29_04760		Bacteroides ovatus BFG-261	UVR39440.1			5
NXV29_04770		Bacteroides ovatus BFG-261	UVR39442.1			5
NXW52_09840		Bacteroides ovatus BFG-464	UVP12877.1			5
NXW52_09850		Bacteroides ovatus BFG-464	UVP12879.1			5
NXW19_04385		Bacteroides ovatus BFG-465	UVP78135.1			5
NXW19_04370		Bacteroides ovatus BFG-465	UVP78132.1			5
INE80_01255 (Egl_1)		Bacteroides ovatus CL06T03C20	QUT79278.1			5
INE80_01257 (Egl_2)		Bacteroides ovatus CL06T03C20	QUT79280.1			5
I6J65_13360		Bacteroides ovatus FDAARGOS_1235	QRQ54567.1			5
I6J65_13350		Bacteroides ovatus FDAARGOS_1235	QRQ54565.1			5
FOC41_16530		Bacteroides ovatus FDAARGOS_733	QGT72466.1			5
FOC41_16540		Bacteroides ovatus FDAARGOS_733	QGT72468.1			5
RJT06_16830		Bacteroides ovatus H-1813	MDV3118207.1			5
RJT06_16840		Bacteroides ovatus H-1813	MDV3118209.1			5
BACOV975_00815		Bacteroides ovatus V975	SCV07059.1			5
BACOV975_00813		Bacteroides ovatus V975	SCV07057.1			5
BOVAC1_5198		Bacteroides ovatus VPIC145	CAG9870843.1			5
BOVAC1_5196		Bacteroides ovatus VPIC145	CAG9870841.1			5
KQP70_11885		Bacteroides salyersiae WAL7960	UYU43288.1			5
KQP70_11880		Bacteroides salyersiae WAL7960	UYU43287.1			5
NQ505_06150		Bacteroides sp. D2	UWO01013.1			5
NQ505_06140		Bacteroides sp. D2	UWO01011.1			5
H8796_04435		Bacteroides sp. M10	QNL39860.1			5
H8796_04445		Bacteroides sp. M10	QNL39862.1			5
FQN58_21160		Bacteroides xylanisolvens APCS1/XY	QUR45527.1			5
FQN58_21150		Bacteroides xylanisolvens APCS1/XY	QUR45525.1			5
P2T61_10875		Bacteroides xylanisolvens AY11-1	WET88134.1			5
P2T61_10885		Bacteroides xylanisolvens AY11-1	WET88136.1			5
NXW81_04290		Bacteroides xylanisolvens BFG-319	UVQ11942.1			5
NXW81_04300		Bacteroides xylanisolvens BFG-319	UVQ11944.1			5
NXX95_04340		Bacteroides xylanisolvens BFG-514	UVP25135.1			5
NXX95_04350		Bacteroides xylanisolvens BFG-514	UVP25137.1			5
NXX35_06440		Bacteroides xylanisolvens BFG-566	UVR75258.1			5
NXX35_06430 (fragment)		Bacteroides xylanisolvens BFG-566	UVR75256.1			5
INE92_03599 (Egl_2)		Bacteroides xylanisolvens CL11T00C03	QUT31549.1			5
INE92_03597 (Egl_1)		Bacteroides xylanisolvens CL11T00C03	QUT31547.1			5
INE93_03680 (Egl_2)		Bacteroides xylanisolvens CL11T00C41	QUT26202.1			5
INE93_03678 (Egl_1)		Bacteroides xylanisolvens CL11T00C41	QUT26200.1			5
GFH35_14070		Bacteroides xylanisolvens funn3	QRM99696.1			5
GFH35_14060		Bacteroides xylanisolvens funn3	QRM99694.1			5
FKZ68_03960		Bacteroides xylanisolvens H207	QDH53449.1			5
FKZ68_03970		Bacteroides xylanisolvens H207	QDH53451.1			5
BXY_21130		Bacteroides xylanisolvens XB1A	CBK67191.1			5
BXY_21150		Bacteroides xylanisolvens XB1A	CBK67193.1			5
MVA48_14460 (fragment)		Blastococcus sp. PRF04-17	UOY00204.1			5
B0B51_10750		blood disease bacterium A2-HR MARDI	AQW31539.1			5
endoglucanase (fragment)		blood disease bacterium R223	AAY33899.1			5
BDB_120007 (EgL)		blood disease bacterium R229	CCA80961.1			5
Egl (fragment)		blood disease bacterium R229 MAFF301552	ADD24725.1			5
endoglucanase (fragment)		blood disease bacterium R233	AAY33903.1			5
endoglucanase (fragment)		blood disease bacterium R506	AAY33900.1			5
endoglucanase (fragment)		blood disease bacterium T520	AAS46799.1			5
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