Glycoside Hydrolase Family 5 / Subf 41

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (223); Uniprot accession (11);
All (222) Bacteria (221) Eukaryota (1)
| 1 | 2 | 3 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 BH709_20440   Klebsiella pneumoniae KP36 AOT66392.1     41
 AXK16_06680   Klebsiella pneumoniae KP38731 AQU59932.1     41
 ACG94_19455   Klebsiella pneumoniae KP5 AOZ39146.1     41
 BN49_1057   Klebsiella pneumoniae Kp52.145 CDO12818.1     41
 AN966_23290   Klebsiella pneumoniae KP617 ALH87655.1     41
 A4U70_05445   Klebsiella pneumoniae kp757 ARN25131.1     41
 AQD68_19295   Klebsiella pneumoniae KpN01 ALQ86143.1     41
 AQD73_19255   Klebsiella pneumoniae KpN06 ALQ91639.1     41
 B8O08_06425   Klebsiella pneumoniae KPN1481 ART04583.1     41
 B8O09_10430   Klebsiella pneumoniae KPN1482 ARS99545.1     41
 WM91_20870   Klebsiella pneumoniae Kpn223 ANK43340.1     41
 B8F96_22470   Klebsiella pneumoniae KPN528 ART13135.1     41
 WM92_10630   Klebsiella pneumoniae Kpn555 ANK46764.1     41
 ABA76_21325   Klebsiella pneumoniae KPNIH36 ANK29107.1     41
 WM47_21095   Klebsiella pneumoniae KPNIH39 ANK23446.1     41
 BB745_01050   Klebsiella pneumoniae Kp_Goe_121641 APQ24898.1     41
 BB750_05775   Klebsiella pneumoniae Kp_Goe_149473 APP34045.1     41
 BB751_05770   Klebsiella pneumoniae Kp_Goe_149832 APP45635.1     41
 BB786_05775   Klebsiella pneumoniae Kp_Goe_152021 APP63240.1     41
 BB747_05365   Klebsiella pneumoniae Kp_Goe_33208 APM69043.1     41
 BB789_06250   Klebsiella pneumoniae Kp_Goe_39795 APM57975.1     41
 BB790_05900   Klebsiella pneumoniae Kp_Goe_62629 APM52096.1     41
 BB748_05365   Klebsiella pneumoniae Kp_Goe_71070 APM74667.1     41
 BB749_05955   Klebsiella pneumoniae Kp_Goe_821588 APP40123.1     41
 BB744_01106   Klebsiella pneumoniae Kp_Goe_822579 APD43105.1     41
 BB746_05920   Klebsiella pneumoniae Kp_Goe_822917 APM63543.1     41
 BB784_05770   Klebsiella pneumoniae Kp_Goe_827024 APP51504.1     41
 BB785_05770   Klebsiella pneumoniae Kp_Goe_827026 APP57371.1     41
 BB787_05770   Klebsiella pneumoniae KP_Goe_828304 APP69104.1     41
 CEV20_20040   Klebsiella pneumoniae MLST-15 ASG60486.1     41
 BTE50_24475   Klebsiella pneumoniae MNCRE53 APM16482.1     41
 BTE51_24295   Klebsiella pneumoniae MNCRE69 APM04819.1     41
 BTE52_22320   Klebsiella pneumoniae MNCRE78 APM10284.1     41
 MS6671_39390   Klebsiella pneumoniae MS6671 CEP73581.1     41
 A6P56_05775   Klebsiella pneumoniae NY9 APV23795.1     41
 PMK1_00547   Klebsiella pneumoniae PMK1 AIT00048.1     41
 A7B01_04535   Klebsiella pneumoniae SKGH01 ANE68935.1     41
 A79E_1026   Klebsiella pneumoniae subsp. pneumoniae 1084 AFQ64399.1     41
 P243_1114   Klebsiella pneumoniae subsp. pneumoniae 1158 AJC03215.1     41
 Kpn23412_1057   Klebsiella pneumoniae subsp. pneumoniae 234-12 AKE74565.1     41
 VK055_4444   Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1 AIK82987.1     41
 CI103_05760   Klebsiella pneumoniae subsp. pneumoniae AUSMDU00008079 AST72978.1     41
 AKK42_05295   Klebsiella pneumoniae subsp. pneumoniae HKUOPLC ALD54757.1     41
 KPHS_41440   Klebsiella pneumoniae subsp. pneumoniae HS11286 AEW62842.1     41
 KP13_02562   Klebsiella pneumoniae subsp. pneumoniae Kp13 AHE43025.1     41
 A593_05535   Klebsiella pneumoniae subsp. pneumoniae KP5-1 AIE00026.1     41
 KPNIH1_20645   Klebsiella pneumoniae subsp. pneumoniae KPNIH1 AIE24582.1     41
 KPNIH10_20645   Klebsiella pneumoniae subsp. pneumoniae KPNIH10 AIA38269.1     41
 KPNIH24_08065   Klebsiella pneumoniae subsp. pneumoniae KPNIH24 AID95186.1     41
 KPNIH27_20005   Klebsiella pneumoniae subsp. pneumoniae KPNIH27 AIA43525.1     41
 KPNIH29_20825   Klebsiella pneumoniae subsp. pneumoniae KPNIH29 AIX70830.1     41
 KPNIH30_20835   Klebsiella pneumoniae subsp. pneumoniae KPNIH30 AIX80576.1     41
 KPNIH31_20050   Klebsiella pneumoniae subsp. pneumoniae KPNIH31 AIX85788.1     41
 KPNIH32_21695   Klebsiella pneumoniae subsp. pneumoniae KPNIH32 AIW78206.1     41
 KPNIH33_21900   Klebsiella pneumoniae subsp. pneumoniae KPNIH33 AIW72695.1     41
 B1U44_02665   Klebsiella pneumoniae subsp. pneumoniae KPN_KPC_HUG_07 AQT13521.1     41
 KPR0928_20130   Klebsiella pneumoniae subsp. pneumoniae KPR0928 AIE29885.1     41
 KPN_03070   Klebsiella pneumoniae subsp. pneumoniae MGH 78578 ABR78471.1 A6TD00   41
 KP1_4338   Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 BAH64859.1 C4XCK1   41
 AWN66_23335   Klebsiella pneumoniae subsp. pneumoniae NUHL24835 AMA18477.1     41
 Q770_24775   Klebsiella pneumoniae subsp. pneumoniae PittNDM01 AIG85318.1     41
 RJA_05485   Klebsiella pneumoniae subsp. pneumoniae RJA166 ARV38695.1     41
 RJF2_20125   Klebsiella pneumoniae subsp. pneumoniae RJF293 AMA26549.1     41
 RJF9_21245   Klebsiella pneumoniae subsp. pneumoniae RJF999 AMA31906.1     41
 AOG31_05800   Klebsiella pneumoniae subsp. pneumoniae TGH10 AMV55674.1     41
 AOG30_06555   Klebsiella pneumoniae subsp. pneumoniae TGH13 AOR88678.1     41
 AOD72_06170   Klebsiella pneumoniae subsp. pneumoniae TGH8 AMV50527.1     41
 KPR_1216   Klebsiella pneumoniae subsp. rhinoscleromatis SB3432 CCI75446.1     41
 BAU11_17745   Klebsiella pneumoniae TH1 ANN53385.1     41
 AC565_22300   Klebsiella pneumoniae U25 ALP80108.1     41
 AM275_16670   Klebsiella pneumoniae UCLAOXA232KP_Pt0 AOM91104.1     41
 AM277_09715   Klebsiella pneumoniae UCLAOXA232KP_Pt1 AOM94901.1     41
 AM278_15360   Klebsiella pneumoniae UCLAOXA232KP_PtX AON01582.1     41
 H224_05750   Klebsiella pneumoniae UHKPC07 AKR93468.1     41
 H222_05745   Klebsiella pneumoniae UHKPC33 AKR98930.1     41
 A7321_08115   Klebsiella pneumoniae W14 ANF08801.1     41
 KPYH43_c1026   Klebsiella pneumoniae YH43 BAS33886.1     41
 SE02_14985   Klebsiella pneumoniae yzusk-4 AKH00340.1     41
 AWV58_14935   Klebsiella quasipneumoniae HKUOPA4 ASR22042.1     41
 AWV59_18570   Klebsiella quasipneumoniae HKUOPJ4 ASR27491.1     41
 AWV60_08545   Klebsiella quasipneumoniae HKUOPL4 ASR30435.1     41
 B8P98_05805   Klebsiella sp. KPN1705 ASV18841.1     41
 BJF97_22940   Klebsiella sp. LTGPAF-6F AOV13722.1     41
 BWI76_22385   Klebsiella sp. M5al ARI10099.1     41
 Kvar_0996   Klebsiella variicola At-22 ADC56924.1 D3RJC0   41
 SP68_09535   Klebsiella variicola DSM 15968 AJE89484.1     41
 KR75_02975   Klebsiella variicola DX120E AJA93823.1     41
 BBD63_20895   Klebsiella variicola GJ1 AQL17585.1     41
 BBD64_20895   Klebsiella variicola GJ2 AQL22675.1     41
 BBD65_20890   Klebsiella variicola GJ3 AQL28433.1     41
 AKG92_08205   Klebsiella variicola HKUOPLA ALD05249.1     41
 AWN63_05075   Klebsiella variicola LMG 23571 APW86802.1     41
 ALGA_0931   Marinifilaceae bacterium SPP2 BAX79318.1     41
 AUP74_03276   Microbulbifer aggregans CCB-MM1 AOS98642.1     41
 VN24_20500   Paenibacillus beijingensis DSM 24997 AJY77890.1     41
 PM3016_4915   Paenibacillus mucilaginosus 3016 AFC31647.1     41
 PM3016_4315   Paenibacillus mucilaginosus 3016 AFC31085.1     41
 B2K_25460   Paenibacillus mucilaginosus K02 AFH63992.1     41
 B2K_22360   Paenibacillus mucilaginosus K02 AFH63404.1     41
 KNP414_04915 (Msn1)   Paenibacillus mucilaginosus KNP414 AEI43440.1     41
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