Glycoside Hydrolase Family 5 / Subf 41

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (363); Uniprot accession (11);
All (362) Bacteria (361) Eukaryota (1)
| 1 | 2 | 3 | 4 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 WM93_00820   Klebsiella pneumoniae ATCC 35657 APS93226.1     41
 Kpn2146_4313   Klebsiella pneumoniae ATCC BAA-2146 AHI37663.1     41
 CWN90_05820   Klebsiella pneumoniae AUSMDU00003562 ATZ97885.1     41
 CWN89_05810   Klebsiella pneumoniae AUSMDU00008119 AUA03395.1     41
 CHX41_19360   Klebsiella pneumoniae BIC-1 ASS81074.1     41
 B9G35_22840   Klebsiella pneumoniae BK13043 ARS96113.1     41
 FH42_11370   Klebsiella pneumoniae blaNDM-1 AIJ41286.1     41
 A9J37_05705   Klebsiella pneumoniae BR ANK15456.1     41
 AA595_05775   Klebsiella pneumoniae BWHC1 AVU24145.1     41
 AGE75_22155   Klebsiella pneumoniae CAV1016 APB52583.1     41
 AGE78_11025   Klebsiella pneumoniae CAV1042 APP20131.1     41
 AGG09_19835   Klebsiella pneumoniae CAV1193 ALR26392.1     41
 AGE86_10050   Klebsiella pneumoniae CAV1217 APP25651.1     41
 AB186_19725   Klebsiella pneumoniae CAV1344 AKL30370.1     41
 ABY63_12830   Klebsiella pneumoniae CAV1392 AKK86770.1     41
 AGG42_26175   Klebsiella pneumoniae CAV1417 APM22640.1     41
 AGG69_19305   Klebsiella pneumoniae CAV1453 APM27025.1     41
 AB187_01275   Klebsiella pneumoniae CAV1596 AKL44565.1     41
 CLH64_25480   Klebsiella pneumoniae CCUG 70742 AWR57322.1     41
 CLH68_09420   Klebsiella pneumoniae CCUG 70747 AWR63228.1     41
 CHC10_04071   Klebsiella pneumoniae CDC 0106 AWX30130.1     41
 C9J88_06370   Klebsiella pneumoniae CFSAN054110 AVS25680.1     41
 C9J89_17235   Klebsiella pneumoniae CFSAN054111 AVS22323.1     41
 D364_15650   Klebsiella pneumoniae CG43 AGX39123.1     41
 A6U99_05640   Klebsiella pneumoniae CN1 APV18534.1     41
 A6P37_05765   Klebsiella pneumoniae CR14 APV29566.1     41
 CU074_16450   Klebsiella pneumoniae CRKP-1215 ATX30837.1     41
 CU075_03235   Klebsiella pneumoniae CRKP-2297 ATX23007.1     41
 DLJ83_04415   Klebsiella pneumoniae DA33140 AWO34519.1     41
 DLJ66_15565   Klebsiella pneumoniae DA33141 AWO41931.1     41
 DLJ67_13470   Klebsiella pneumoniae DA33144 AWO46840.1     41
 BKL84_21120   Klebsiella pneumoniae DA48896 AVO18487.1     41
 H218_05585   Klebsiella pneumoniae DMC1097 AKR82357.1     41
 BVU42_21135   Klebsiella pneumoniae DT1 AUJ41691.1     41
 BV506_21475   Klebsiella pneumoniae DT12 AUJ46977.1     41
 BCV48_20835   Klebsiella pneumoniae ED2 AOE27752.1     41
 BCV49_22115   Klebsiella pneumoniae ED23 AOE32871.1     41
 CYE02_21980   Klebsiella pneumoniae F44 AUH92692.1     41
 AL516_06165   Klebsiella pneumoniae FDAARGOS_156 AVG04061.1     41
 CRN28_01165   Klebsiella pneumoniae FDAARGOS_436 ATM30015.1     41
 CRN23_00450   Klebsiella pneumoniae FDAARGOS_439 ATM35363.1     41
 CRN19_02715   Klebsiella pneumoniae FDAARGOS_440 ATM41290.1     41
 CRN65_24755   Klebsiella pneumoniae FDAARGOS_442 ATM50671.1     41
 CRN73_05110   Klebsiella pneumoniae FDAARGOS_443 ATM52560.1     41
 CRN70_05325   Klebsiella pneumoniae FDAARGOS_444 ATM58423.1     41
 CO702_00230   Klebsiella pneumoniae FDAARGOS_445 ATF42355.1     41
 CRN69_17155   Klebsiella pneumoniae FDAARGOS_446 ATM66293.1     41
 CRN71_05650   Klebsiella pneumoniae FDAARGOS_447 ATM69799.1     41
 BKY56_022005   Klebsiella pneumoniae GN-2 AUY67249.1     41
 KPGSU103_C11090   Klebsiella pneumoniae GSU10-3 BBE02391.1     41
 P244_1085   Klebsiella pneumoniae HK787 AJB31043.1     41
 C0066_21320   Klebsiella pneumoniae HS09565 AUN69375.1     41
 C0065_21885   Klebsiella pneumoniae HS102438 AUN84813.1     41
 CW753_00580   Klebsiella pneumoniae HZW25 AVI88307.1     41
 CTI63_05390   Klebsiella pneumoniae INF042 ATR40934.1     41
 CTI65_05390   Klebsiella pneumoniae INF059 ATR46253.1     41
 CTI61_05515   Klebsiella pneumoniae INF157 ATR29888.1     41
 CTI59_25325   Klebsiella pneumoniae INF158 ATR27916.1     41
 CTI74_05515   Klebsiella pneumoniae INF163 ATR56687.1     41
 CTI75_05520   Klebsiella pneumoniae INF164 ATR62221.1     41
 CTI54_06005   Klebsiella pneumoniae INF249 ATQ92837.1     41
 CTI69_05520   Klebsiella pneumoniae INF274 ATR73312.1     41
 CTI68_05520   Klebsiella pneumoniae INF278 ATR67783.1     41
 CTI52_06005   Klebsiella pneumoniae INF322 ATQ87440.1     41
 A8C11_06210   Klebsiella pneumoniae isolate 11 AOF03532.1     41
 A8N26_12300   Klebsiella pneumoniae isolate blood sample 2 AOD04760.1     41
 BB788_05920   Klebsiella pneumoniae isolate Kp_Goe_154414 APM42529.1     41
 AU361_12240   Klebsiella pneumoniae J1 ALU54233.1     41
 N559_1164   Klebsiella pneumoniae JM45 AGT22933.1     41
 CYE04_21290   Klebsiella pneumoniae JS187 AUH86923.1     41
 B5G58_01180   Klebsiella pneumoniae K66-45 ARM20640.1     41
 KPN2242_18310   Klebsiella pneumoniae KCTC 2242 AEJ99545.1     41
 KLP1_07310   Klebsiella pneumoniae KP-1 ALK12436.1     41
 CXB26_05930   Klebsiella pneumoniae KP1766 AUD16506.1     41
 CXB24_05930   Klebsiella pneumoniae KP1768 AUD27374.1     41
 BH709_20440   Klebsiella pneumoniae KP36 AOT66392.1     41
 AXK16_06680   Klebsiella pneumoniae KP38731 AQU59932.1     41
 ACG94_19455   Klebsiella pneumoniae KP5 AOZ39146.1     41
 BN49_1057   Klebsiella pneumoniae Kp52.145 CDO12818.1     41
 DBV09_05810   Klebsiella pneumoniae Kp589 AWA32627.1     41
 AN966_23290   Klebsiella pneumoniae KP617 ALH87655.1     41
 CYD98_22150   Klebsiella pneumoniae KP69 AUH81367.1     41
 A4U70_05445   Klebsiella pneumoniae kp757 ARN25131.1     41
 C1D07_00725   Klebsiella pneumoniae Kp81 AUQ27773.1     41
 C5Z24_09760   Klebsiella pneumoniae KPHS1249 AVK66717.1     41
 AQD68_19295   Klebsiella pneumoniae KpN01 ALQ86143.1     41
 AQD73_19255   Klebsiella pneumoniae KpN06 ALQ91639.1     41
 B8O08_06425   Klebsiella pneumoniae KPN1481 ART04583.1     41
 B8O09_10430   Klebsiella pneumoniae KPN1482 ARS99545.1     41
 WM91_20870   Klebsiella pneumoniae Kpn223 ANK43340.1     41
 B8F96_22470   Klebsiella pneumoniae KPN528 ART13135.1     41
 WM92_10630   Klebsiella pneumoniae Kpn555 ANK46764.1     41
 ABA76_21325   Klebsiella pneumoniae KPNIH36 ANK29107.1     41
 WM47_21095   Klebsiella pneumoniae KPNIH39 ANK23446.1     41
 C3F39_20740   Klebsiella pneumoniae KPNIH48 AUY21034.1     41
 C2U49_13675   Klebsiella pneumoniae KPNIH49 AUU95771.1     41
 C2U50_10495   Klebsiella pneumoniae KPNIH50 AUV37128.1     41
 BB745_01050   Klebsiella pneumoniae Kp_Goe_121641 APQ24898.1     41
 BB750_05775   Klebsiella pneumoniae Kp_Goe_149473 APP34045.1     41
 BB751_05770   Klebsiella pneumoniae Kp_Goe_149832 APP45635.1     41
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