Glycoside Hydrolase Family 5 / Subf 41

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (223); Uniprot accession (11);
All (222) Bacteria (221) Eukaryota (1)
| 1 | 2 | 3 |
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 KNP414_05546   Paenibacillus mucilaginosus KNP414 AEI44070.1     41
 Pjdr2_0680   Paenibacillus sp. JDR-2 ACS99359.1 C6CT19   41
 CIC07_21560   Paenibacillus sp. RUD330 ASS68430.1     41
 GYMC10_2436   Paenibacillus sp. Y412MC10 ACX64714.1 D3E9Q7   41
 TE10_22230   Raoultella ornithinolytica S12 AJF74592.1     41
 Sde_1121 (Gly5R)   Saccharophagus degradans 2-40 ABD80383.1 Q21LP6   41
 M5M_16790 (fragment)   Simiduia agarivorans SA1 = DSM 21679 AFV00489.1
 M5M_16795 (fragment)   Simiduia agarivorans SA1 = DSM 21679 AFV00490.1     41
 TERTU_4090   Teredinibacter turnerae T7901 ACR14317.1 C5BUE5   41
 YE5303_39551   Yersinia enterocolitica (type O:5) str. YE53/03 CCQ42663.1     41
 CH48_1562   Yersinia enterocolitica 2516-87 AJJ26572.1     41
 CH49_3561   Yersinia enterocolitica 8081 AJJ24411.1     41
 LI89_21365   Yersinia enterocolitica FORC-002 ALG47177.1     41
 FORC2_0075   Yersinia enterocolitica FORC_002 AKF36222.1     41
 XM56_00345   Yersinia enterocolitica KNG22703 ALG76969.1     41
 YE4100   Yersinia enterocolitica subsp. enterocolitica 8081 CAL14117.1 A1JSX4   41
 YE105_C3829   Yersinia enterocolitica subsp. palearctica 105.5R(r) ADZ44323.1     41
 Y11_43230   Yersinia enterocolitica subsp. palearctica Y11 CBY29448.1     41
 YEW_DY16990   Yersinia enterocolitica W22703 CBX73276.1     41
 CH47_3631   Yersinia enterocolitica WA AJI82535.1     41
 BB936_00380   Yersinia enterocolitica YE165 AOF13160.1     41

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