Glycoside Hydrolase Family 5 / Subf 41

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (223); Uniprot accession (11);
All (222) Bacteria (221) Eukaryota (1)
| 1 | 2 | 3 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 AV939_12175   Alteromonas sp. Mac1 AMJ87257.1     41
 AV940_11940   Alteromonas sp. Mac2 AMJ91120.1     41
 A6F57_02120   Alteromonas stellipolaris PQQ-44 ANB24109.1     41
 CJA_3784 (Man5E)   Cellvibrio japonicus Ueda107 ACE84240.1 B3PIQ2   41
 CBR65_15585   Cellvibrio sp. PSBB006 ARU28748.1     41
 EcWSU1_03673   Enterobacter cloacae EcWSU1 AEW75101.1     41
 M942_06180   Enterobacter cloacae P101 AHE72721.1     41
 ABT55_20830   Enterobacter cloacae UW5 AKM88948.1     41
 BH714_21405   Enterobacter ludwigii EN-119 AOT45618.1     41
 BFV63_11030   Enterobacter xiangfangensis LMG27195 AOP91408.1     41
 EM595_0609   Erwinia gerundensis EM595 CUU22846.1     41
 BN863_30860   Formosa agariphila KMM 3901 CDF80798.1     41
 BN863_30890 (probable fragment)   Formosa agariphila KMM 3901 CDF80801.1     41
 Glaag_3288   Glaciecola sp. 4H-3-7+YE-5 AEE24222.1     41
 ABY61_03750   Klebsiella aerogenes CAV1320 AKK80417.1     41
 ORF   Klebsiella aerogenes EA1509E CCG30095.1     41
 AL497_21120   Klebsiella aerogenes FDAARGOS_139 AMQ62106.1     41
 EAG7_01621   Klebsiella aerogenes G7 AML35367.1     41
 EAE_18940   Klebsiella aerogenes KCTC 2190 AEG98695.1     41
 A225_4598   Klebsiella michiganensis E718 AFN33845.1     41
 J415_08965   Klebsiella michiganensis HKOPL1 AHW87324.1     41
 CF000_11170   Klebsiella michiganensis K516 ASK73615.1     41
 CKQ55_19040   Klebsiella michiganensis K518 ASZ57178.1     41
 KOX_00745   Klebsiella michiganensis KCTC 1686 AEX01894.1     41
 HR38_26845   Klebsiella michiganensis M1 AIE71926.1     41
 AM394_11890   Klebsiella oxytoca AR_0147 ARB21862.1     41
 AGF18_14940   Klebsiella oxytoca CAV1015 APB45135.1     41
 AB184_25230   Klebsiella oxytoca CAV1099 AKL08379.1     41
 AB181_25510   Klebsiella oxytoca CAV1335 AKL25310.1     41
 AB185_13200   Klebsiella oxytoca CAV1374 AKL34800.1     41
 AGH21_11620   Klebsiella oxytoca CAV1752 APM31234.1     41
 KOJKO3_c4395   Klebsiella oxytoca JKo3 BAS42409.1     41
 KONIH1_23070   Klebsiella oxytoca KONIH1 AID91860.1     41
 A8C23_19325   Klebsiella pneumoniae AOF11444.1     41
 A8C11_06210   Klebsiella pneumoniae AOF03532.1     41
 RH201207_01395   Klebsiella pneumoniae CZQ43873.1     41
 A8N26_12300   Klebsiella pneumoniae AOD04760.1     41
 BB788_05920   Klebsiella pneumoniae APM42529.1     41
 CES89_22865   Klebsiella pneumoniae ASG36072.1     41
 Sequence 9951 from patent US 6610836   Klebsiella pneumoniae AAR50234.1     41
 LQ47_04235   Klebsiella pneumoniae 13004 AIW98344.1     41
 BWG70_05375   Klebsiella pneumoniae 1756 APV13147.1     41
 KPNJ1_01174   Klebsiella pneumoniae 30660/NJST258_1 AHM83580.1     41
 KPNJ2_01201   Klebsiella pneumoniae 30684/NJST258_2 AHM77981.1     41
 KU54_05735   Klebsiella pneumoniae 32192 AJB56300.1     41
 KPK_1052   Klebsiella pneumoniae 342 ACI11517.1 B5XV72   41
 LI86_05745   Klebsiella pneumoniae 34618 AJB74764.1     41
 J052_05635   Klebsiella pneumoniae 500_1420 AKR87976.1     41
 CI946_24570   Klebsiella pneumoniae 721005 ASV93294.1     41
 BB783_01105   Klebsiella pneumoniae 825795-1 APU33998.1     41
 CJU70_18365   Klebsiella pneumoniae 911021 ASV26842.1     41
 WM86_20425   Klebsiella pneumoniae AATZP ANF42670.1     41
 AM426_24580   Klebsiella pneumoniae AR_0047 ARW99955.1     41
 AM428_09895   Klebsiella pneumoniae AR_0049 APR47000.1     41
 AM447_17660   Klebsiella pneumoniae AR_0068 ARA47866.1     41
 AM477_20905   Klebsiella pneumoniae AR_0098 ARA60057.1     41
 AM359_23140   Klebsiella pneumoniae AR_0112 ARX05548.1     41
 AM360_20835   Klebsiella pneumoniae AR_0113 ASA00469.1     41
 AM362_00845   Klebsiella pneumoniae AR_0115 ARA50607.1     41
 AM364_00580   Klebsiella pneumoniae AR_0117 ARA39047.1     41
 AM367_15065   Klebsiella pneumoniae AR_0120 ASB06945.1     41
 AM372_11780   Klebsiella pneumoniae AR_0125 ASB12187.1     41
 AM373_24460   Klebsiella pneumoniae AR_0126 ARZ95728.1     41
 AM376_17225   Klebsiella pneumoniae AR_0129 ARX51245.1     41
 AM385_10455   Klebsiella pneumoniae AR_0138 ASA09130.1     41
 AM386_03725   Klebsiella pneumoniae AR_0139 ASC20973.1     41
 AM390_26115   Klebsiella pneumoniae AR_0143 ARX47121.1     41
 AM392_24890   Klebsiella pneumoniae AR_0145 ASC42117.1     41
 AM393_04605   Klebsiella pneumoniae AR_0146 ARX18190.1     41
 AM395_22595   Klebsiella pneumoniae AR_0148 ASC36079.1     41
 AM399_05685   Klebsiella pneumoniae AR_0152 ASC27412.1     41
 AM404_13010   Klebsiella pneumoniae AR_0158 ARX39190.1     41
 WM93_00820   Klebsiella pneumoniae ATCC 35657 APS93226.1     41
 Kpn2146_4313   Klebsiella pneumoniae ATCC BAA-2146 AHI37663.1     41
 CHX41_19360   Klebsiella pneumoniae BIC-1 ASS81074.1     41
 B9G35_22840   Klebsiella pneumoniae BK13043 ARS96113.1     41
 FH42_11370   Klebsiella pneumoniae blaNDM-1 AIJ41286.1     41
 A9J37_05705   Klebsiella pneumoniae BR ANK15456.1     41
 AGE75_22155   Klebsiella pneumoniae CAV1016 APB52583.1     41
 AGE78_11025   Klebsiella pneumoniae CAV1042 APP20131.1     41
 AGG09_19835   Klebsiella pneumoniae CAV1193 ALR26392.1     41
 AGE86_10050   Klebsiella pneumoniae CAV1217 APP25651.1     41
 AB186_19725   Klebsiella pneumoniae CAV1344 AKL30370.1     41
 ABY63_12830   Klebsiella pneumoniae CAV1392 AKK86770.1     41
 AGG42_26175   Klebsiella pneumoniae CAV1417 APM22640.1     41
 AGG69_19305   Klebsiella pneumoniae CAV1453 APM27025.1     41
 AB187_01275   Klebsiella pneumoniae CAV1596 AKL44565.1     41
 D364_15650   Klebsiella pneumoniae CG43 AGX39123.1     41
 A6U99_05640   Klebsiella pneumoniae CN1 APV18534.1     41
 A6P37_05765   Klebsiella pneumoniae CR14 APV29566.1     41
 H218_05585   Klebsiella pneumoniae DMC1097 AKR82357.1     41
 BCV48_20835   Klebsiella pneumoniae ED2 AOE27752.1     41
 BCV49_22115   Klebsiella pneumoniae ED23 AOE32871.1     41
 CO702_00230   Klebsiella pneumoniae FDAARGOS_445 ATF42355.1     41
 P244_1085   Klebsiella pneumoniae HK787 AJB31043.1     41
 AU361_12240   Klebsiella pneumoniae J1 ALU54233.1     41
 N559_1164   Klebsiella pneumoniae JM45 AGT22933.1     41
 B5G58_01180   Klebsiella pneumoniae K66-45 ARM20640.1     41
 KPN2242_18310   Klebsiella pneumoniae KCTC 2242 AEJ99545.1     41
 KLP1_07310   Klebsiella pneumoniae KP-1 ALK12436.1     41
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