Glycoside Hydrolase Family 5 / Subf 41

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (363); Uniprot accession (11);
All (362) Bacteria (361) Eukaryota (1)
| 1 | 2 | 3 | 4 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 AV939_12175   Alteromonas sp. Mac1 AMJ87257.1     41
 AV940_11940   Alteromonas sp. Mac2 AMJ91120.1     41
 A6F57_02120   Alteromonas stellipolaris PQQ-44 ANB24109.1     41
 CJA_3784 (Man5E)   Cellvibrio japonicus Ueda107 ACE84240.1 B3PIQ2   41
 CBR65_15585   Cellvibrio sp. PSBB006 ARU28748.1     41
 AM379_03550   Enterobacter cloacae complex sp. FDA-CDC-AR_0132 AVO99506.1     41
 AM410_11560   Enterobacter cloacae complex sp. FDA-CDC-AR_0164 AWC85035.1     41
 EcWSU1_03673   Enterobacter cloacae EcWSU1 AEW75101.1     41
 M942_06180   Enterobacter cloacae P101 AHE72721.1     41
 ABT55_20830   Enterobacter cloacae UW5 AKM88948.1     41
 BH714_21405   Enterobacter ludwigii EN-119 AOT45618.1     41
 BFV63_11030   Enterobacter xiangfangensis LMG27195 AOP91408.1     41
 CUC76_20890   Enterobacteriaceae bacterium S05 AWB63865.1     41
 EM595_0609   Erwinia gerundensis EM595 CUU22846.1     41
 OYT1_ch1949   Ferriphaselus amnicola OYT1 BBE51475.1     41
 BN863_30860   Formosa agariphila KMM 3901 CDF80798.1     41
 BN863_30890 (probable fragment)   Formosa agariphila KMM 3901 CDF80801.1     41
 Glaag_3288   Glaciecola sp. 4H-3-7+YE-5 AEE24222.1     41
 AM334_18295   Klebsiella aerogenes AR_0007 ATY02629.1     41
 AM336_20450   Klebsiella aerogenes AR_0009 ATY07773.1     41
 AM441_17790   Klebsiella aerogenes AR_0062 AVF00374.1     41
 AM407_17870   Klebsiella aerogenes AR_0161 AWD04759.1     41
 ABY61_03750   Klebsiella aerogenes CAV1320 AKK80417.1     41
 ORF   Klebsiella aerogenes EA1509E CCG30095.1     41
 AL497_21120   Klebsiella aerogenes FDAARGOS_139 AMQ62106.1     41
 EAG7_01621   Klebsiella aerogenes G7 AML35367.1     41
 EAE_18940   Klebsiella aerogenes KCTC 2190 AEG98695.1     41
 DMP75_25295   Klebsiella michiganensis AACKY AWT21340.1     41
 CSC12_2476   Klebsiella michiganensis AR375 AWF51835.1     41
 A225_4598   Klebsiella michiganensis E718 AFN33845.1     41
 J415_08965   Klebsiella michiganensis HKOPL1 AHW87324.1     41
 CF000_11170   Klebsiella michiganensis K516 ASK73615.1     41
 CKQ55_19040   Klebsiella michiganensis K518 ASZ57178.1     41
 KOX_00745   Klebsiella michiganensis KCTC 1686 AEX01894.1     41
 HR38_26845   Klebsiella michiganensis M1 AIE71926.1     41
 CSC17_4366   Klebsiella oxytoca AR380 AWF36939.1     41
 AM355_00870   Klebsiella oxytoca AR_0028 AVE75895.1     41
 AM394_11890   Klebsiella oxytoca AR_0147 ARB21862.1     41
 AGF18_14940   Klebsiella oxytoca CAV1015 APB45135.1     41
 AB184_25230   Klebsiella oxytoca CAV1099 AKL08379.1     41
 AB181_25510   Klebsiella oxytoca CAV1335 AKL25310.1     41
 AB185_13200   Klebsiella oxytoca CAV1374 AKL34800.1     41
 AGH21_11620   Klebsiella oxytoca CAV1752 APM31234.1     41
 CEQ13_01200   Klebsiella oxytoca FDAARGOS_335 AVL78872.1     41
 KOJKO3_c4395   Klebsiella oxytoca JKo3 BAS42409.1     41
 KONIH1_23070   Klebsiella oxytoca KONIH1 AID91860.1     41
 C2U42_34480   Klebsiella oxytoca KONIH2 AUW13975.1     41
 C2U44_06310   Klebsiella oxytoca KONIH4 AUV90724.1     41
 C2U46_04435   Klebsiella oxytoca KONIH5 AUV96961.1     41
 NCTC11355_05430   Klebsiella oxytoca NCTC11355 SQI97472.1     41
 RH201207_01395   Klebsiella pneumoniae CZQ43873.1     41
 CES89_22865   Klebsiella pneumoniae ASG36072.1     41
 CNR480_03276   Klebsiella pneumoniae SPR87651.1     41
 Sequence 9951 from patent US 6610836   Klebsiella pneumoniae AAR50234.1     41
 CYU57_21235   Klebsiella pneumoniae 002SK2 AUH98093.1     41
 LQ47_04235   Klebsiella pneumoniae 13004 AIW98344.1     41
 BWG70_05375   Klebsiella pneumoniae 1756 APV13147.1     41
 BH367_05605   Klebsiella pneumoniae 203 AWQ51570.1     41
 A8C23_19325   Klebsiella pneumoniae 23 AOF11444.1     41
 KPNJ1_01174   Klebsiella pneumoniae 30660/NJST258_1 AHM83580.1     41
 KPNJ2_01201   Klebsiella pneumoniae 30684/NJST258_2 AHM77981.1     41
 KU54_05735   Klebsiella pneumoniae 32192 AJB56300.1     41
 KPK_1052   Klebsiella pneumoniae 342 ACI11517.1 B5XV72   41
 LI86_05745   Klebsiella pneumoniae 34618 AJB74764.1     41
 A9493_03265   Klebsiella pneumoniae 459 AUC26516.1     41
 J052_05635   Klebsiella pneumoniae 500_1420 AKR87976.1     41
 C2861_05460   Klebsiella pneumoniae 616 AWG11272.1     41
 CI946_24570   Klebsiella pneumoniae 721005 ASV93294.1     41
 BB783_01105   Klebsiella pneumoniae 825795-1 APU33998.1     41
 CJU70_18365   Klebsiella pneumoniae 911021 ASV26842.1     41
 WM86_20425   Klebsiella pneumoniae AATZP ANF42670.1     41
 CSC13_4439   Klebsiella pneumoniae AR376 AWF47580.1     41
 CSC25_1161   Klebsiella pneumoniae AR438 AWF08082.1     41
 AM426_24580   Klebsiella pneumoniae AR_0047 ARW99955.1     41
 AM428_09895   Klebsiella pneumoniae AR_0049 APR47000.1     41
 AM445_21035   Klebsiella pneumoniae AR_0066 AVF13449.1     41
 AM447_17660   Klebsiella pneumoniae AR_0068 ARA47866.1     41
 AM458_25135   Klebsiella pneumoniae AR_0079 AWE03616.1     41
 AM459_21785   Klebsiella pneumoniae AR_0080 AVO79591.1     41
 AM466_22565   Klebsiella pneumoniae AR_0087 AWS75631.1     41
 AM477_20905   Klebsiella pneumoniae AR_0098 ARA60057.1     41
 AM359_23140   Klebsiella pneumoniae AR_0112 ARX05548.1     41
 AM360_20835   Klebsiella pneumoniae AR_0113 ASA00469.1     41
 AM362_00845   Klebsiella pneumoniae AR_0115 ARA50607.1     41
 AM364_00580   Klebsiella pneumoniae AR_0117 ARA39047.1     41
 AM367_15065   Klebsiella pneumoniae AR_0120 ASB06945.1     41
 AM372_11780   Klebsiella pneumoniae AR_0125 ASB12187.1     41
 AM373_24460   Klebsiella pneumoniae AR_0126 ARZ95728.1     41
 AM376_17225   Klebsiella pneumoniae AR_0129 ARX51245.1     41
 AM385_10455   Klebsiella pneumoniae AR_0138 ASA09130.1     41
 AM386_03725   Klebsiella pneumoniae AR_0139 ASC20973.1     41
 AM390_26115   Klebsiella pneumoniae AR_0143 ARX47121.1     41
 AM392_24890   Klebsiella pneumoniae AR_0145 ASC42117.1     41
 AM393_04605   Klebsiella pneumoniae AR_0146 ARX18190.1     41
 AM395_22595   Klebsiella pneumoniae AR_0148 ASC36079.1     41
 AM399_05685   Klebsiella pneumoniae AR_0152 ASC27412.1     41
 AM400_11575   Klebsiella pneumoniae AR_0153 AWC02052.1     41
 AM404_13010   Klebsiella pneumoniae AR_0158 ARX39190.1     41
 CSB98_3095   Klebsiella pneumoniae AR_0361 AVK30558.1     41
 CSC00_3415   Klebsiella pneumoniae AR_0363 AVJ84821.1     41
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