Activities in Sub Family	Endoglycosylceramidase (EC 3.2.1.123);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (169); Uniprot accession (3);

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
SBOV1_LOCUS6204 (fragment)		Schistosoma bovis	CAH8605406.1			27
SCUR2_LOCUS6189 (fragment)		Schistosoma curassoni	CAH8602243.1			27
SCUR2_LOCUS6196		Schistosoma curassoni	CAH8602361.1			27
SCUR2_LOCUS6836		Schistosoma curassoni	CAH8616419.1			27
SCUR2_LOCUS6195		Schistosoma curassoni	CAH8602347.1			27
SCUR2_LOCUS6188 (fragment)		Schistosoma curassoni	CAH8602229.1			27
SCUR2_LOCUS6838 (fragment)		Schistosoma curassoni	CAH8616457.1			27
SCUR2_LOCUS6191		Schistosoma curassoni	CAH8602270.1			27
SCUR2_LOCUS6837		Schistosoma curassoni	CAH8616434.1			27
SGUI1_LOCUS6360 (fragment)		Schistosoma guineensis	CAH8597823.1			27
SGUI1_LOCUS7037 (fragment)		Schistosoma guineensis	CAH8611767.1			27
SGUI1_LOCUS6369		Schistosoma guineensis	CAH8597977.1			27
SHAE1_LOCUS7149		Schistosoma haematobium	CAH8627985.1			27
SHAE1_LOCUS6460		Schistosoma haematobium	CAH8612276.1			27
SHAE1_LOCUS6466		Schistosoma haematobium	CAH8612428.1			27
SHAE2_LOCUS6630		Schistosoma haematobium	CAH8620069.1			27
SHAE2_LOCUS6623		Schistosoma haematobium	CAH8619935.1			27
SHAE1_LOCUS7148		Schistosoma haematobium	CAH8627970.1			27
SHAE2_LOCUS7276		Schistosoma haematobium	CAH8634178.1			27
SINT1_LOCUS6162		Schistosoma intercalatum	CAH8584828.1			27
SINT1_LOCUS6808		Schistosoma intercalatum	CAH8598782.1			27
SINT2_LOCUS6212		Schistosoma intercalatum	CAH8586390.1			27
SINT2_LOCUS6858		Schistosoma intercalatum	CAH8600006.1			27
SJCHGC02838		Schistosoma japonicum	AAW25069.1			27
Smp_119550 (fragment)		Schistosoma mansoni	CAY19074.1			27
Smp_120050 (fragment)		Schistosoma mansoni	CAY19094.1			27
Smp_120660 or Smp_187070 (fragment)		Schistosoma mansoni	CAY19124.1 CAZ38230.1			27
Smp_155570		Schistosoma mansoni	CAZ33725.1			27
Smp_193630 (fragment)		Schistosoma mansoni	CAZ38970.1			27
Smp_194220 (fragment)		Schistosoma mansoni	CAZ39055.1			27
Smp_194230 (fragment)		Schistosoma mansoni	CAZ39056.1			27
Smp_177700 (fragment)		Schistosoma mansoni	CAZ37129.1			27
Smp_181910 (fragment)		Schistosoma mansoni	CAZ37678.1			27
Smp_182090 (fragment)		Schistosoma mansoni	CAZ37698.1			27
Smp_185860 (fragment)		Schistosoma mansoni	CAZ38099.1			27
Smp_187010 (fragment)		Schistosoma mansoni	CAZ38225.1			27
Smp_187410 (fragment)		Schistosoma mansoni	CAZ38267.1			27
Smp_164170 (possible fragment)		Schistosoma mansoni Puerto Rico	CAZ35197.1 CCD80873.1			27
Smp_177380 (fragment)		Schistosoma mansoni Puerto Rico	CAZ37094.1 CCD76693.1			27
SMRG1_LOCUS4773 (fragment)		Schistosoma margrebowiei	CAH8560787.1			27
SMRG1_LOCUS4772		Schistosoma margrebowiei	CAH8560771.1			27
SMRG1_LOCUS6432		Schistosoma margrebowiei	CAH8602564.1			27
SMRG1_LOCUS6439		Schistosoma margrebowiei	CAH8602731.1			27
SMRG1_LOCUS6431		Schistosoma margrebowiei	CAH8602548.1			27
SMTH1_LOCUS6992 (fragment)		Schistosoma mattheei	CAH8575328.1			27
SMTH1_LOCUS6991 (fragment)		Schistosoma mattheei	CAH8575312.1			27
SMTH1_LOCUS7752 (fragment)		Schistosoma mattheei	CAH8589127.1			27
SMTH1_LOCUS7751		Schistosoma mattheei	CAH8589113.1			27
SMTH1_LOCUS6996		Schistosoma mattheei	CAH8575436.1			27
SRDH2_LOCUS7216 (fragment)		Schistosoma rodhaini	CAH8634050.1			27
SRDH1_LOCUS3546 (fragment)		Schistosoma rodhaini	CAH8542729.1			27
SRDH2_LOCUS7204		Schistosoma rodhaini	CAH8633864.1			27
SRDH2_LOCUS7201		Schistosoma rodhaini	CAH8633829.1			27
SRDH1_LOCUS5924 (fragment)		Schistosoma rodhaini	CAH8614189.1			27
SRDH1_LOCUS6462 (fragment)		Schistosoma rodhaini	CAH8628065.1			27
SRDH1_LOCUS7188		Schistosoma rodhaini	CAH8645756.1			27
SRDH2_LOCUS4851 (fragment)		Schistosoma rodhaini	CAH8576952.1			27
SRDH1_LOCUS6463		Schistosoma rodhaini	CAH8628079.1			27
SRDH1_LOCUS7184		Schistosoma rodhaini	CAH8645681.1			27
SRDH1_LOCUS7600		Schistosoma rodhaini	CAH8656478.1			27
SRDH1_LOCUS6461		Schistosoma rodhaini	CAH8628051.1			27
SRDH2_LOCUS4843		Schistosoma rodhaini	CAH8576829.1			27
SRDH1_LOCUS6459 (fragment)		Schistosoma rodhaini	CAH8628034.1			27
SRDH2_LOCUS4778 (fragment)		Schistosoma rodhaini	CAH8574852.1			27
SRDH1_LOCUS5923		Schistosoma rodhaini	CAH8614157.1			27
SRDH2_LOCUS7203		Schistosoma rodhaini	CAH8633862.1			27
SRDH2_LOCUS3357		Schistosoma rodhaini	CAH8530660.1			27
SRDH2_LOCUS7630 (fragment)		Schistosoma rodhaini	CAH8643614.1			27
SSPN1_LOCUS6057 (fragment)		Schistosoma spindale	CAI2731824.1			27
SSPN1_LOCUS6046 (fragment)		Schistosoma spindale	CAI2731806.1			27
SSPN1_LOCUS6050		Schistosoma spindale	CAI2731810.1			27
SSPN1_LOCUS6059		Schistosoma spindale	CAI2731828.1			27
SSPN1_LOCUS6057 (fragment)		Schistosoma spindale	CAI2731825.1			27
SSPN1_LOCUS6046 (fragment)		Schistosoma spindale	CAI2731805.1			27
SSPN1_LOCUS6059		Schistosoma spindale	CAI2731827.1			27
SSPN1_LOCUS6047 (fragment)		Schistosoma spindale	CAI2731807.1			27
SSPN1_LOCUS6049		Schistosoma spindale	CAI2731809.1			27
SSPN1_LOCUS6059 (fragment)		Schistosoma spindale	CAI2731829.1			27
SSPN1_LOCUS6050		Schistosoma spindale	CAI2731811.1			27
STRK1_LOCUS6188 (fragment)		Schistosoma turkestanicum	CAH8537775.1			27
STRK1_LOCUS5803		Schistosoma turkestanicum	CAH8530577.1			27
STRK1_LOCUS5802		Schistosoma turkestanicum	CAH8530562.1			27
STRK1_LOCUS6190 (fragment)		Schistosoma turkestanicum	CAH8537806.1			27
STRK1_LOCUS6193		Schistosoma turkestanicum	CAH8537845.1			27
4419		Spizellomyces punctatus DAOM BR117 (Spipu1)				27
8398		Spizellomyces punctatus DAOM BR117 (Spipu1)				27
15468		Symbiodinium microadriaticum CCMP2467 (Symmic1)				27
9638		Symbiodinium microadriaticum CCMP2467 (Symmic1)				27
9538		Symbiodinium microadriaticum CCMP2467 (Symmic1)				27
9637		Symbiodinium microadriaticum CCMP2467 (Symmic1)				27
448583		Thamnidium elegans v1.0 (Thaele1)				27
61952		Tremella mesenterica v1 (Treme1)				27
TREG1_LOCUS10738		Trichobilharzia regenti	CAH8868366.1			27
TREG1_LOCUS10737		Trichobilharzia regenti	CAH8868364.1			27
TREG1_LOCUS10808 (fragment)		Trichobilharzia regenti	CAH8868520.1			27
TSZD1_LOCUS11342		Trichobilharzia szidati	CAH8868369.1			27
TSZD1_LOCUS11339		Trichobilharzia szidati	CAH8868363.1			27
153925		Trichoderma asperelloides T203 v1.0 (Triasper1)				27
469995		Trichoderma asperellum TR356 v1.0 (Triasp1)				27
TrA_002321		Trichoderma asperellum FT101	UKZ86493.1			27
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