Activities in Sub Family	Endoglycosylceramidase (EC 3.2.1.123);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (170); Uniprot accession (3);

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
421683		Absidia repens NRRL 1336 v1.0 (Absrep1)				27
I4U23_024811		Adineta vaga	UJR21736.1			27
I4U23_006679		Adineta vaga	UJR25328.1			27
I4U23_008963		Adineta vaga	UJR27685.1			27
I4U23_016245		Adineta vaga	UJR12067.1			27
4348		Arthrobotrys oligospora ATCC 24927 (Artol1)				27
47781		Aspergillus albertensis v1.0 (Aspalbe1)				27
16429		Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)				27
155082		Aspergillus arachidicola v1.0 (Aspara19utr)				27
305453		Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)				27
2495		Aspergillus bombycis NRRL 26010 (Aspbom1)				27
126368		Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)				27
271586		Aspergillus campestris IBT 28561 v1 (Aspcam1)				27
60573		Aspergillus candidus CBS 102.13 v1.0 (Aspcand1)				27
G4B11_005938		Aspergillus flavus AF13	QMW42568.1			27
AFCA_006736		Aspergillus flavus CA14	UDD59314.1			27
F9C07_2282858		Aspergillus flavus NRRL 3357	QRD89368.1			27
G4B84_005891		Aspergillus flavus NRRL3357	QMW30510.1			27
26447		Aspergillus flavus NRRL3357 (Aspfl1)				27
2282858		Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)				27
103946		Aspergillus fumigatus A1163 (Aspfu_A1163_1)				27
5958		Aspergillus fumigatus Af293 (Aspfu1)				27
32371		Aspergillus leporis CBS 151.66 v1.0 (Asplep1)				27
230783		Aspergillus minisclerotigenes v1.0 (Aspmin1)				27
102823		Aspergillus nomius v1.0 (Aspnom1)				27
9752		Aspergillus nomius NRRL 13137 (Aspnom13137_1)				27
448135		Aspergillus novofumigatus IBT 16806 v1 (Aspnov1)				27
118151		Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)				27
AO090012000006		Aspergillus oryzae RIB40	BAE60253.1			27
5706		Aspergillus oryzae RIB40 (Aspor1)				27
186073		Aspergillus parasiticus CBS 117618 v1.0 (Asppar1)				27
381938		Aspergillus parvisclerotigenus CBS 121.62 v1.0 (Asppari1)				27
264881		Aspergillus pseudocaelatus CBS 117616 v1.0 (Asppsec1)				27
282462		Aspergillus pseudonomius CBS 119388 v1.0 (Asppsen1)				27
18149		Aspergillus pseudotamarii CBS 117625 v1.0 (Asppset1)				27
72408		Aspergillus sergii CBS 130017 v1.0 (Aspser1)				27
56821		Aspergillus taichungensis IBT 19404 v1.0 (Asptaic1)				27
264770		Aspergillus tamarii CBS 117626 v1.0 (Asptam1)				27
4430		Aspergillus terreus NIH 2624 (Aspte1)				27
561038		Aspergillus transmontanensis CBS 130015 (Asptra1)				27
9491		Aspergillus udagawae IFM 46973 (Aspuda1)				27
197631		Backusella circina FSU 941 v1 (Bacci1)				27
353210		Basidiobolus meristosporus CBS 931.73 (Basme2finSC)				27
363414		Basidiobolus meristosporus CBS 931.73 (Basme2finSC)				27
5478		Beauveria bassiana ARSEF 2860 (Beaba1)				27
249		Beauveria brongniartii RCEF 3172 (Corbr1)				27
486067		Benjaminiella poitrasii RSA 903 v1.0 (Benpoi1)				27
2003		Cafeteria roenbergensis BVI (Cafroe1)				27
3814		Cafeteria roenbergensis BVI (Cafroe1)				27
8379		Cafeteria roenbergensis BVI (Cafroe1)				27
FKW44_004678 (fragment)		Caligus rogercresseyi	QQP52504.1			27
183086		Calocera cornea (Calco1)				27
564105		Calocera viscosa v1 (Calvi1)				27
183275		Chrysochromulina tobin CCMP291 (Chrsp_1)				27
176651		Chrysochromulina tobin CCMP291 (Chrsp_1)				27
295725		Chytridium lagenaria Arg66 v1.0 (Chylag1)				27
384551		Chytridium lagenaria Arg66 v1.0 (Chylag1)				27
602635		Chytriomyces hyalinus JEL632 v1.0 (Chyhya1)				27
632863		Chytriomyces hyalinus JEL632 v1.0 (Chyhya1)				27
619571		Chytriomyces hyalinus JEL632 v1.0 (Chyhya1)				27
602637		Chytriomyces hyalinus JEL632 v1.0 (Chyhya1)				27
632861		Chytriomyces hyalinus JEL632 v1.0 (Chyhya1)				27
544826		Chytriomyces sp. MP 71 v1.0 (Chytri1)				27
1080448		Chytriomyces sp. MP 71 v1.0 (Chytri1)				27
1080447		Chytriomyces sp. MP 71 v1.0 (Chytri1)				27
1138787		Chytriomyces sp. MP 71 v1.0 (Chytri1)				27
1165230		Chytriomyces sp. MP 71 v1.0 (Chytri1)				27
633147		Cladochytrium polystomum WB228 (Clapol1_1)				27
804990		Cladochytrium polystomum WB228 (Clapol1_1)				27
763741		Cladochytrium polystomum WB228 (Clapol1_1)				27
856176		Cladochytrium polystomum WB228 (Clapol1_1)				27
828618		Cladochytrium polystomum WB228 (Clapol1_1)				27
856182		Cladochytrium polystomum WB228 (Clapol1_1)				27
ORF		Cordyceps fumosorosea Ifr AsC	AIK98138.1			27
A9K55_000635		Cordyceps militaris ATCC 34164	ATY67020.1			27
4540		Cordyceps militaris CM01 (Cormi1)				27
286728		Cunninghamella echinulata NRRL 1382 v1.0 (Cunech1)				27
244479		Cunninghamella echinulata NRRL 1382 v1.0 (Cunech1)				27
endoglycoceramidase (EGCase)	3.2.1.123	Cyanea nozakii	BAB16369.1 BAB16370.1	Q9GV15 Q9GV16		27
DDND1_LOCUS8171		Dicrocoelium dendriticum	CAH8604681.1			27
DDND1_LOCUS8171		Dicrocoelium dendriticum	CAH8604686.1			27
431388		Dissophora ornata CBS 347.77 v1.0 (Disorn1)				27
66695		Emiliania huxleyi (Emihu1)				27
86831		Endogone sp FLAS 59071 (Endsp1)				27
420497		Entophlyctis helioformis JEL805 v1.0 (Enthel1)				27
560979		Fimicolochytrium jonesii JEL569 v1.0 (Fimjon1)				27
525073		Fusarium tricinctum MPI-SDFR-AT-0044 (Fustri1)				27
651182		Fusarium commune MPI-SDFR-AT-0072 (Fusco1)				27
CEK26_003014		Fusarium fujikuroi Augusto2	QGJ01570.1			27
CEK27_003009		Fusarium fujikuroi CSV1	QGI70680.1			27
CEK25_002981		Fusarium fujikuroi I1.3	QGI88025.1			27
FFUJ_11407		Fusarium fujikuroi IMI 58289	CCT75388.1			27
13935		Fusarium fujikuroi IMI 58289 (Fusfu1)				27
694430		Fusarium oxysporum f. sp. albedinis isolate 9 v1.0 (Fusoxalb1)				27
24469		Fusarium oxysporum f. sp. conglutinans race 2 54008 (PHW808) (Fusoxcon1)				27
14312		Fusarium oxysporum f. sp. cubense tropical race 4 54006 (II5) (Fusoxcub1)				27
19509		Fusarium oxysporum f. sp. lycopersici 4287 v2 (Fusox2)				27
12567		Fusarium oxysporum f. sp. lycopersici MN25 (FoMN25) NRRL 54003 (Fusoxlyc1)				27
8373		Fusarium oxysporum f. sp. melonis (FoMelon) NRRL 26406 (Fusoxmel1)				27
5500		Fusarium oxysporum f. sp. pisi HDV247 (Fusoxpis1)				27
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