Glycoside Hydrolase Family 5 / Subf 27

Activities in Sub FamilyEndoglycosylceramidase (EC 3.2.1.123);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (169); Uniprot accession (3);
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3DSubf
 endoglycoceramidase (EGCase) 3.2.1.123 pubmed
Cyanea nozakii BAB16369.1
BAB16370.1
Q9GV15
Q9GV16
  27
 endoglycoceramidase (EGCase) 3.2.1.123 pubmed
Hydra magnipapillata BAD20464.1 Q6L6S1   27
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