Activities in Sub Family	Endoglycosylceramidase (EC 3.2.1.123);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (169); Uniprot accession (3);

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
8598		Fusarium oxysporum f. sp. radicis-lycopersici 26381 (CL57) (Fusoxrad1)				27
7725		Fusarium oxysporum f. sp. raphani 54005 (Fusoxrap1)				27
14234		Fusarium oxysporum f. sp. vasinfectum 25433 (Cotton) (Fusoxvas1)				27
FOBC_16700		Fusarium oxysporum Fo47	QKD62446.2 QKD62446.1			27
3559		Fusarium oxysporum Fo47 (FusoxFo47)				27
764742		Fusarium oxysporum MPI-CAGE-CH-0212 v1.0 (Fusoxys1)				27
658303		Fusarium oxysporum MPI-SDFR-AT-0094 v1.0 (Fusoxy1)				27
4128		Fusarium oxysporum NRRL 32931 (Fusox32931)				27
15938		Fusarium proliferatum ET1 (Fuspro1)				27
5580		Fusarium proliferatum NRRL 62905 (Fuspr1)				27
527333		Fusarium redolens MPI-CAGE-AT-0023 v1.0 (Fusre1)				27
526485		Fusarium tricinctum F194 (Fustr1)				27
11256		Fusarium verticillioides 7600 v2 (Fusve2)				27
454166		Geranomyces variabilis JEL559 v1.0 (Gervar1)				27
246860		Gongronella butleri v1.0 (Gonbut1)				27
46636		Guillardia theta CCMP2712 (Guith1)				27
157591		Guillardia theta CCMP2712 (Guith1)				27
362161		Halteromyces radiatus CBS 162.75 v1.0 (Halrad1)				27
86747		Helobdella robusta (Helro1)				27
HAMR1_LOCUS3278		Heterobilharzia americana	CAH8494716.1			27
HAMR2_LOCUS8492		Heterobilharzia americana	CAH8638940.1			27
HAMR2_LOCUS8457 (fragment)		Heterobilharzia americana	CAH8638321.1			27
HAMR2_LOCUS8456 (fragment)		Heterobilharzia americana	CAH8638307.1			27
ORF (fragment)		Hirsutella thompsonii H3	AIK98137.1			27
2048		Homolaphlyctis polyrhiza JEL142 v1.0 (Hompol1)				27
647983		Hyaloraphidium curvatum SAG235-1 v1.0 (Hyacur1)				27
endoglycoceramidase (EGCase)	3.2.1.123	Hydra magnipapillata	BAD20464.1	Q6L6S1		27
471120		Jimgerdemmania flammicorona AD002 (Jimfl_AD_1)				27
147751		Jimgerdemannia flammicorona GMNB39 (Jimfl_GMNB39_1)				27
126766		Jimgerdemannia lactiflua OSC166217 (Jimlac1)				27
ORF		Lagenidium giganteum ARSEF 373	AIK98135.1			27
4038		Lecanicillium (Akanthomyces) lecanii RCEF 1005 (Corco1)				27
LSAA_2128		Lepeophtheirus salmonis IoA-00	CAF2754379.1 CAB4054260.1			27
1522		Lichtheimia corymbifera JMRC:FSU:9682 (Liccor1)				27
197173		Lichtheimia hyalospora FSU 10163 (Lichy1)				27
LRAMOSA09953		Lichtheimia ramosa	CDS08592.1			27
425938		Lobosporangium transversale NRRL 3116 v1.0 (Lobtra1)				27
Mp_3g06760 (fragment)		Marchantia polymorpha subsp. ruderalis Tak-1	BBN04676.1			27
MPTK1_3g06760 (fragment)		Marchantia polymorpha subsp. ruderalis Takaragaike-1	BFI09641.1			27
MPTK2_3g06760 (fragment)		Marchantia polymorpha subsp. ruderalis Takaragaike-2	BFI29865.1			27
2340		Metarhizium acridum CQMa 102 (Metac1)				27
7435		Metarhizium anisopliae ARSEF 549 (Metani1)				27
G6M90_00g033190 (EgcsE)		Metarhizium brunneum 4556	QLI68417.1			27
ORF (fragment)		Metarhizium reniforme IndGH96	AIK98136.1			27
5261		Metarhizium robertsii ARSEF 23 (Metro1)				27
6867		Dactylellina haptotyla CBS 200.50 v1 (Monha1)				27
2925		Dactylellina haptotyla CBS 200.50 v1 (Monha1)				27
855		Mortierella alpina AD071 (MoalAD071_1)				27
5595		Mortierella alpina AD072 (MoalAD072_1)				27
5253		Mortierella alpina AD072 (MoalAD072_1)				27
1889		Mortierella alpina CK1249 (MoalCK1249_1)				27
5934		Mortierella alpina CK1249 (MoalCK1249_1)				27
889387		Mortierella elongata AG-77 v2.0 (Morel2)				27
47914		Mortierella elongata AG-77 v2.0 (Morel2)				27
418760		Mortierella elongata MPI-CAGE-AA-0104 v1.0 (Morel_U14_1)				27
482072		Mortierella elongata MPI-CAGE-AA-0104 v1.0 (Morel_U14_1)				27
302860		Mortierella elongata NVP64 v1.0 (MoeNVP64_1)				27
299489		Mortierella elongata NVP64 v1.0 (MoeNVP64_1)				27
527612		Mortierella multidivaricata RSA 2152 T v1.0 (Mormul1)				27
593		Mortierella sp. AD094 (MospAD094_1)				27
476780		Mortierella sp. nov. GBAus27b (MorGBAus27b_1)				27
1155		Mortierella sp. KOD 1030 (MospKOD1030_1)				27
802		Mortierella sp. KOD 1030 (MospKOD1030_1)				27
801		Mortierella sp. KOD 1030 (MospKOD1030_1)				27
7942		Mortierella sp. NVP41 (MospNVP41_1)				27
2557		Mortierella sp. NVP41 (MospNVP41_1)				27
1327307		Mucor circinelloides MU402 v1.0 (Muccir1_3)				27
KARACHINF001_ LOCUS 3059		Naegleria fowleri	CAG4710704.1			27
32211		Naegleria gruberi (Naegr1)				27
2105		Neosartorya fischeri NRRL 181 (Neofi1)				27
850519		Obelidium mucronatum JEL802 v1.0 (Obemuc1)				27
940578		Obelidium mucronatum JEL802 v1.0 (Obemuc1)				27
328587		Obelidium mucronatum JEL802 v1.0 (Obemuc1)				27
EGX50094.1		Orbilia oligospora ATCC 24927	EGX50094.1			27
512203		Paecilomyces variotii (Byssochlamys spectabilis) CBS 101075 (Paevar1)				27
197476		Paecilomyces variotii (Byssochlamys spectabilis) CBS144490 HYG1 v1.0 (Paevar_HGY_1)				27
29881		Penicillium chrysogenum (Pench1)				27
370		Penicillium flavigenum IBT 14082 (Penfla1)				27
9459		Penicillium subrubescens (Pensub1)				27
14837		Pochonia chlamydosporia 170 (Pocchl1)				27
499136		Polychytrium aggregatum JEL109 v1.0 (Polagg1_1)				27
632593		Polychytrium aggregatum JEL109 v1.0 (Polagg1_1)				27
598697		Polychytrium aggregatum JEL109 v1.0 (Polagg1_1)				27
597886		Polychytrium aggregatum JEL109 v1.0 (Polagg1_1)				27
621841		Polychytrium aggregatum JEL109 v1.0 (Polagg1_1)				27
247142		Powellomyces hirtus BR81 v1.0 (Powhir1)				27
8323		Purpureocillium lilacinum PLFJ-1 (Purli1)				27
JDV02_000048		Purpureocillium takamizusanense PT3	UNI13291.1			27
716473		Rhizophagus cerebriforme DAOM 227022 v1.0 (Rhice1_1)				27
713608		Rhizophagus diaphanus v1.0 (Rhidi1)				27
544713		Rhizophagus irregularis A4 v1.0 (RhiirA4)				27
476207		Rhizophagus irregularis A5 v1.0 (RhiirA5)				27
7008		Saksenaea vasiformis B4078 (Sakvas1)				27
SBOV2_LOCUS6934 (fragment)		Schistosoma bovis	CAH8614361.1			27
SBOV2_LOCUS6933		Schistosoma bovis	CAH8614348.1			27
SBOV2_LOCUS6292 (fragment)		Schistosoma bovis	CAH8600470.1			27
SBOV2_LOCUS6288 (fragment)		Schistosoma bovis	CAH8600381.1			27
SBOV1_LOCUS6861 (fragment)		Schistosoma bovis	CAH8619828.1			27
SBOV1_LOCUS6862 (fragment)		Schistosoma bovis	CAH8619842.1			27
SBOV1_LOCUS6209 (fragment)		Schistosoma bovis	CAH8605530.1			27
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