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Glycoside Hydrolase Family 38

Activities in FamilyMannosyl-1-phosphodiester α-1,P-mannosidase (EC 3.2.1.-);
Mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-);
Mannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113);
Mannosyl-oligosaccharide α-1,3-1,6-mannosidase (EC 3.2.1.114);
Mannosyl-oligosaccharide α-1,6-mannosidase / exo-α-1,6-mannosidase (EC 3.2.1.163);
α-mannosidase (EC 3.2.1.24);
Mechanism Retaining a
3D Structure Statusmannosidase fold
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorNot known
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (12170); Uniprot accession (86); PDB accession (82); 3D entries (13); cryst (2)
Summary
Download GH38 (12985) Taxonomic display Structure (13 - 2 cryst) Characterized (46)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 26 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 HYE68_004862   Fusarium pseudograminearum Class2-1C QPC74110.1    
 NXS19_011819   Fusarium pseudograminearum Fp22-2 UZP44007.1    
 555033   Fusarium redolens MPI-CAGE-AT-0023 v1.0 (Fusre1)      
 178089   Fusarium solani FSSC 5 v1.0 (Fusso1)      
 LCI18_000774   Fusarium solani-melongenae CRI 24-3 UPK89839.1    
 104574   Fusarium equiseti G328 (Fuseq1)      
 157356   Fusarium tricinctum F194 (Fustr1)      
 123325   Nectria haematococca mpVI 77-13-4 (Necha2)      
 FVRRES_11572   Fusarium venenatum A3/5 CEI38881.1    
 463421   Fusarium venenatum MPI-CAGE-CH-0201 (Fusven1)      
 16703   Fusarium verticillioides 7600 v2 (Fusve2)      
 16702   Fusarium verticillioides 7600 v2 (Fusve2)      
 571318   Gaertneriomyces semiglobifer Barr 43 v1.0 (Gaesem1)      
 1639   Galdieria sulphuraria 002 (Gsu002_1)      
 1154   Galdieria sulphuraria 002 (Gsu002_1)      
 1785   Galdieria sulphuraria 002 (Gsu002_1)      
 1079   Galdieria sulphuraria 002 (Gsu002_1)      
 2867   Galdieria sulphuraria 074W (Galsul1)      
 5727   Galdieria sulphuraria 074W (Galsul1)      
 4009   Galdieria sulphuraria 074W (Galsul1)      
 1154   Galdieria sulphuraria SAG 21.92 (GsuSAG2192_1)      
 1785   Galdieria sulphuraria SAG 21.92 (GsuSAG2192_1)      
 1079   Galdieria sulphuraria SAG 21.92 (GsuSAG2192_1)      
 3573   Galdieria sulphuraria SAG 21.92 (GsuSAG2192_1)      
 5254   Galdieria sulphuraria SAG 21.92 (GsuSAG2192_1)      
 α-mannosidase 2   Galeruca daurica WVS81691.1    
 RCJMB04_18f23 (fragment)   Gallus gallus CAH65326.1    
 606491   Ganoderma boninense G3 v1.0 (Ganbon1)      
 790813   Ganoderma boninense G3 v1.0 (Ganbon1)      
 550943   Ganoderma lucidum G.260125-1 v1.0 (Ganluc1)      
 11948   Ganoderma sinense ZZ0214-1 (Gansi1)      
 73062   Ganoderma sp. 10597 SS1 v1.0 (Gansp1)      
 3080999   Gautieria morchelliformis GMNE.BST v1.0 (Gaumor1_1)      
 616732   Geopyxis carbonaria DOB1671 v1.0 (Geocar1)      
 448462   Geranomyces variabilis JEL559 v1.0 (Gervar1)      
 2218150   Gigaspora rosea v1.0 (Gigro1)      
 523602   Gilbertella persicaria var. persicaria CBS 190.32-T v1.0 (Gilper1)      
 460641   Gilbertella persicaria var. persicaria CBS 190.32-T v1.0 (Gilper1)      
 ORF (short fragment)   Gladiolus grandiflorus ADM18311.1    
 1087   Glarea lozoyensis ATCC 20868 (Glalo1)      
 577496   Globomyces pollinis-pini Arg68 v1.0 (Glopol1)      
 819350   Gloeopeniophorella convolvens OM19405 v1.0 (Glocon1)      
 75705   Gloeophyllum trabeum ATCC 11539 (Glotr1_1)      
 393227   Glonium stellatum (Glost2)      
 α-mannosidase (fragment)   Glossina morsitans morsitans ADD18519.1    
 α-1,2-mannosidase (LMann;GmLMann;LOC100806748) 3.2.1.113 Glycine max XP_003548841.1
AIX48008.1		 I1MN42  
 295189   Gongronella butleri v1.0 (Gonbut1)      
 303889   Gongronella butleri v1.0 (Gonbut1)      
 GMON_LOCUS4671   Gordionus sp. m RMFG-2023 CAK9296985.1    
 GMON_LOCUS5408   Gordionus sp. m RMFG-2023 CAK9298029.1    
 GMON_LOCUS8788   Gordionus sp. m RMFG-2023 CAK9303127.1    
 GMON_LOCUS5427   Gordionus sp. m RMFG-2023 CAK9298055.1    
 191878   Gorgonomyces haynaldii MP57 v1.0 (Gorhay1)      
 7114   Grosmannia clavigera kw1407 (Grocl1)      
 39786   Guillardia theta CCMP2712 (Guith1)      
 983882   Guyanagaster necrorhiza MCA 3950 v1 (Guyne1)      
 1680544   Gymnopilus junonius AH 44721 v1.0 (Gymjun1)      
 875037   Gymnopus androsaceus JB14 v1 (Gyman1)      
 259432   Gymnopus luxurians FD-317 M1 (Gymlu1)      
 793061   Gyrodon lividus BX v1 (Gyrli1)      
 α-mannosidase protein   Haemaphysalis flava QIE06298.1    
 294117   Halteromyces radiatus CBS 162.75 v1.0 (Halrad1)      
 340403   Halteromyces radiatus CBS 162.75 v1.0 (Halrad1)      
 535760   Helicostylum pulchrum RSA 2064 v1.0 (Helpul1)      
 593239   Helicostylum pulchrum RSA 2064 v1.0 (Helpul1)      
 110840   Helobdella robusta (Helro1)      
 62270   Helobdella robusta (Helro1)      
 187930   Helobdella robusta (Helro1)      
 63909   Helobdella robusta (Helro1)      
 150086   Helobdella robusta (Helro1)      
 89226   Helobdella robusta (Helro1)      
 143339   Helobdella robusta (Helro1)      
 HERILL_LOCUS14900   Hermetia illucens CAD7092548.1    
 HERILL_LOCUS8243 (fragment)   Hermetia illucens CAD7085397.1    
 HERILL_LOCUS7708   Hermetia illucens CAD7084832.1    
 HERILL_LOCUS7709 (fragment)   Hermetia illucens CAD7084833.1    
 HERILL_LOCUS8991   Hermetia illucens CAD7086199.1    
 HERILL_LOCUS7710 (fragment)   Hermetia illucens CAD7084834.1    
 HERILL_LOCUS8243 (fragment)   Hermetia illucens CAD7085396.1    
 155812   Heterobasidion annosum v2.0 (Hetan2)      
 HAMR1_LOCUS11606   Heterobilharzia americana CAH8649384.1    
 HAMR1_LOCUS10735 (fragment)   Heterobilharzia americana CAH8634233.1    
 HAMR1_LOCUS10736 (fragment)   Heterobilharzia americana CAH8634247.1    
 HAMR1_LOCUS7390   Heterobilharzia americana CAH8572218.1    
 HAMR2_LOCUS9643   Heterobilharzia americana CAH8658369.1    
 HAMR2_LOCUS10356 (fragment)   Heterobilharzia americana CAH8667603.1    
 HAMR2_LOCUS6694 (fragment)   Heterobilharzia americana CAH8600926.1    
 1186919   Hexagonia nitida CIRM-BRFM 1802 (Hexnit1)      
 I7I50_01927   Histoplasma capsulatum G186AR QSS71184.1    
 5512   Histoplasma capsulatum NAm1 (Hisca1)      
 I7I53_04498   Histoplasma capsulatum var. duboisii H88 QSS56318.1    
 I7I51_04320   Histoplasma capsulatum WU24 QSS62143.1    
 α-mannosidase II (Man2A1;ManA2) 3.2.1.114
3.2.1.114		 Homo sapiens AAC50302.1
AAH43416.1
AAI42657.1
AAI42697.1
ACM84601.1
BAA10017.1
CAH33909.1
CAL47687.1
CBA12848.1
CBA34888.1
NP_002363.1		 A5PKX5
Q16706		  
 α-mannosidase a (Man2B1;ManB;LaMan;LMann;HsLMann) (lysosomal) 3.2.1.24
3.2.1.113		 Homo sapiens AAC51362.1
AAB03816.1
AAC34130.1
AAC50811.1
AAC50812.1
AAH00736.1
ABA84560.1
ACM80454.1
ACM82884.1
AIX48010.1
BAD93158.1
BAF84261.1
BAG64471.1
CAD68121.1
CAH33914.1
CBA12853.1
CBA34893.1
NP_000519.1		 A8K6A7
B4E0K9
O00754
Q59E90
Q93093		  
 α-mannosidase IIx (Man2A2;Man2Ax) 3.2.1.24 Homo sapiens BAA09510.1
AAA92022.1
AAI36449.1
BAF82552.1
BAG57210.1
BAG58516.1
BAG61252.1
BAH14521.1
CAH33912.1
CBA12851.1
CBA34891.1
NP_006113.1		 B4DEU9
B4DIK4
B4DRE0
B7ZA35
P49641		  
 neutral α-mannosidase (Man2C1;6A8;6A8B) (cytosolic) 3.2.1.24 Homo sapiens AAC00190.2
AAC00568.1
AAH50550.1
AAH80191.1
ACM82923.1
AEE61026.1
BAD92378.1
BAG62758.1
CAB66810.1
CAH33915.1
CBA12854.1
CBA34894.1
NP_006706.1		 A0A140VJN9
B4DVP6
Q13358
Q9NTJ4		  
 α-1,6-mannosidase (Man2B2;KIAA0935) 3.2.1.163 Homo sapiens CAD89971.1
AAH33307.1
AAH36836.1
AAH94773.1
ADO22337.1
BAA76779.1
BAA76779.2
BAG52093.1
BAH13490.1
CAF86562.1
NP_056089.1
XP_052620.6		 A0A384NYH9
B3KQN1
B7Z754
Q05BN7
Q4VC00
Q9Y2E5
Q9Y2E5		  
 5018   Homolaphlyctis polyrhiza JEL142 v1.0 (Hompol1)      
 1902   Homolaphlyctis polyrhiza JEL142 v1.0 (Hompol1)      
 predicted protein   Hordeum vulgare subsp. vulgare BAJ94660.1    
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