Glycoside Hydrolase Family 38

Activities in Familyα-mannosidase (EC 3.2.1.24); mannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide α-1,3-1,6-mannosidase (EC 3.2.1.114); α-2-O-mannosylglycerate hydrolase (EC 3.2.1.170); mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 7
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorNot known
External resourcesCAZypedia; MEGAZYME;
Statistics GenBank accession (3793); Uniprot accession (537); PDB accession (63); 3D entries (7); cryst (2)
All (3427) Archaea (59) Bacteria (2963) Eukaryota (403) unclassified (2) Structure (7 - 2 cryst) Characterized (45)
| 1 | 2 | 3 | 4 | 5 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AMAN, partial (fragment)   Acanthinevania sp. 240 ASN78182.1    
 AMAN, partial (fragment)   Acanthinevania sp. 242 ASN78183.1    
 AMAN, partial (fragment)   Acanthinevania sp. 271 ASN78185.1    
 AMAN, partial (fragment)   Acanthinevania sp. 289 ASN78192.1    
 AMAN, partial (fragment)   Acanthinevania sp. 292 ASN78194.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56101.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56315.1    
 ALNC14_000460 (Alnc14c1g41)   Albugo laibachii Nc14 CCA13903.1    
 AMAN, partial (fragment)   Alobevania gattiae ASN78169.1    
 ACCB07842 (fragment)   Apis cerana AEY60223.1    
 ACCB09944 (fragment)   Apis cerana AEY60742.1    
 Aa1_7515 (fragment)   Arabidopsis arenosa CARE-1 AAR15492.1 Q6V5C5  
 α-mannosidase (LMann;AtLMann;At3g26720)   Arabidopsis thaliana AAK62592.1
AAM47314.1
AEE77203.1
AEE77204.1
AIX48006.1
ANM65468.1
ANM65469.1
ANM65470.1
BAB01735.1
BAH56863.1
CAA66821.1
CAA72432.1
NP_189306.1
P94078  
 At5g13980   Arabidopsis thaliana AAN15620.1
AAM20555.1
AED91968.1
AED91969.1
AED91970.1
BAB11126.1
BAD93831.1
BAD94717.1
NP_196902.1
Q8LPJ3
Q9FFX7
 
 At5g66150/K2A18.23   Arabidopsis thaliana BAB10420.1
AED98165.1
ANM70390.1
ANM70391.1
NP_201416.1
Q9FKW9  
 α-mannosidase II (AtGMII;At5g14950) 3.2.1.114 Arabidopsis thaliana CAC01814.1
AAK96611.1
AAL38616.1
AAY90120.1
AED92095.1
CAH33905.1
CBA12844.1
CBA34884.1
NP_196999.1
Q940T6
Q9LFR0
 
 EGX52778.1   Arthrobotrys oligospora ATCC 24927 EGX52778.1    
 ORF   Ascaris suum ADY40773.1    
 ORF   Ascaris suum ADY40800.1    
 ORF   Ascaris suum ADY41578.1    
 ORF   Ascaris suum ADY40731.1    
 ORF (fragment)   Ascaris suum ADY40786.1    
 ORF (fragment)   Ascaris suum ADY46025.1    
 ORF (fragment)   Ascaris suum ADY48332.1    
 mannosidase II (AfAms1)   Aspergillus fumigatus YJ-407 AAW49442.1 Q5I5K3  
 AN2936.2   Aspergillus nidulans FGSC A4 EAA63507.1 Q5B944  
 α-mannosidase   Aspergillus nidulans T222 AAB70514.1 O13344  
 An02g11720   Aspergillus niger CBS 513.88 CAK37873.1 A2QEN9  
 AO090005001458   Aspergillus oryzae RIB40 BAE56379.1 Q2UPY6  
 ORF (fragment)   Belgica antarctica ABF72867.1    
 α-mannosidase (Man2B1;ManB) (lysosomal) 3.2.1.24 Bos taurus AAC48763.1
AAB67726.2
NP_776986.2
Q29451 1O7D[A,B,C,D,E]
 α-mannosidase 3.2.1.24 Bos taurus AAE61905.1    
 Unknown (protein for MGC:127782) (fragment)   Bos taurus HEREFORD AAI05161.1 A8YXY9  
 glycoside hydrolase family 38 protein (Bofut4_p162000.1)   Botrytis cinerea T4 CCD54911.1    
 AMAN, partial (fragment)   Brachygaster sp. 286 ASN78190.1    
 p075G11_ORF1 (fragment)   Cadophora finlandica ACP19537.1 C3VES8  
 α-mannosidase (Aman-3;F48C1.1) 3.2.1.24 Caenorhabditis elegans Bristol N2 AAB52345.2
AAM81094.1
CCD62468.1
NP_491568.1
NP_740847.1
NP_740848.1
O01574  
 α-mannosidase (Aman-1;F55D10.1) (lysosomal) 3.2.1.24 Caenorhabditis elegans Bristol N2 AAA81731.2
CCD67087.1
NP_508811.1
Q20829  
 α-mannosidase II (Aman-2;F58H1.1) 3.2.1.114 Caenorhabditis elegans Bristol N2 CAJ55257.1
CAB00104.1
CAH33906.1
CBA12845.1
CBA34885.1
NP_505995.1
Q21010
Q2PJ74
 
 MAN2B1-like protein (fragment)   Callithrix jacchus ABQ22594.1 A6MKK3  
 ORF (fragment)   Callorhinchus milii AFO94440.1    
 ORF (fragment)   Callorhinchus milii AFO95698.1    
 ORF (fragment)   Callorhinchus milii AFP02963.1    
 α-1,2/3/6-mannosidase (JBM;JBAM) (peptide sequencing) (partial) 3.2.1.113
3.2.1.114
3.2.1.24
Canavalia ensiformis   C0HJB3  
 CAALFM_C402360WA (Ams1)   Candida albicans SC5314 AOW29006.1    
 CD36_42240   Candida dubliniensis CD36 CAX42104.1 B9WFT5  
 CAGL0E05148g   Candida glabrata CBS 138 CAG58831.1 Q6FV32  
 SAMEA4029010_CIC11G00000003298   [Candida] intermedia CBS 141442 SGZ56892.1    
 SAMEA4029009_CIC11G00000004730   [Candida] intermedia PYCC 4715 SGZ57524.1    
 CORT_0B00490   Candida orthopsilosis Co 90-125 CCG21770.1    
 CPAR2_500360   Candida parapsilosis CDC317 CCE43810.1    
 lysosomal α-mannosidase (Man2b1;LAM;chLAM) 3.2.1.24 Capra hircus AEZ02307.1    
 Golgi α-mannosidase II   Capra hircus AHD46138.1    
 ORF (fragment)   Capsella grandiflora ADG39048.1 D6PRR6  
 ORF (fragment)   Capsella grandiflora ADG39049.1 D6PRR7  
 ORF (fragment)   Capsella grandiflora ADG39051.1 D6PRR9  
 ORF (fragment)   Capsella rubella AEN83007.1    
 ORF (fragment)   Capsella rubella AEN83012.1    
 α-mannosidase (α-Man) 3.2.1.24 Capsicum annuum ADU20406.1    
 α-mannosidase (ManB;LMann;CpLMann) (lysosomal) 3.2.1.24 Cavia porcellus AAL58982.1
AIX48009.1
Q8VHC8  
 unnamed protein product   Ciona intestinalis CAH33907.1
CBA12846.1
CBA34886.1
   
 CGB_A7550W   Cryptococcus gattii WM276 ADV19851.1    
 CNAG_00696   Cryptococcus neoformans var. grubii H99 AFR92825.2
AFR92825.1
   
 CNA06750   Cryptococcus neoformans var. neoformans JEC21 AAW41087.1 Q5KNE7  
 α-mannosidase 3   Cucumis melo ANZ52439.1    
 α-mannosidase 2   Cucumis melo AOP17810.1    
 α-mannosidase 2   Cucumis melo AOP17811.1    
 α-mannosidase   Cucumis melo AGX24942.1    
 CYFA0S_02e07536g   Cyberlindnera fabianii YJS4271 CDR38869.1    
 Unknown (protein for MGC:110815)   Danio rerio AAH91843.1
AAI65679.1
Q58EM3  
 CH211-131C14.1-001 (fragment)   Danio rerio CAM13190.1
CAM16361.1
A2CED8  
 Unknown (protein for MGC:171587) (fragment)   Danio rerio AAI53981.1 A8KB62  
 DEHA0G18964g   Debaryomyces hansenii CBS767 CAG90819.1 Q6BHK8  
 AMAN, partial (fragment)   Decevania sp. 274 ASN78186.1    
 AMAN, partial (fragment)   Decevania sp. 296 ASN78198.1    
 AMAN, partial (fragment)   Decevania sp. 513 ASN78207.1    
 α-mannosidase (ManA;LMann;DdLMann) 3.2.1.114 Dictyostelium discoideum AAA33224.1
AIX48007.1
P34098  
 Dbus_chr3Rg2438   Drosophila busckii ALC47688.1    
 Dbus_chr3Lg1646   Drosophila busckii ALC44480.1    
 Dbus_chr2Lg1367   Drosophila busckii ALC39282.1    
 Dbus_chr3Rg621   Drosophila busckii ALC45871.1    
 Golgi α-mannosidase IIb (Mα-Man-IIb;GMIIb;CG4606;Dmel_CG4606) 3.2.1.114 Drosophila melanogaster BAA75817.1
AAF55228.2
AAM49872.1
AGB95994.1
AGW52177.1
AHN57340.1
BAC92711.1
NP_650494.2
O97043
Q8MSX9
Q9VF33
 
 GlcNAcMan5GlcNAc2 α-1,6-mannosidase / GlcNAcMan4GlcNAc2 α-1,3-mannosidase / α-mannosidase II (GMII;α-Man-II;CG18474) 3.2.1.114 Drosophila melanogaster CAA54732.1
AAF54375.1
AAF54376.1
AAM50118.1
AGB95795.1
CAA10755.1
CAH33908.1
CBA12847.1
CBA34887.1
NP_524291.2
Q24451 1HTY[A]
1HWW[A]
1HXK[A]
1PS3[A]
1QWN[A]
1QWU[A]
1QX1[A]
1R33[A]
1R34[A]
1TQS[A]
1TQT[A]
1TQU[A]
1TQV[A]
1TQW[A]
2ALW[A]
2F18[A]
2F1A[A]
2F1B[A]
2F7O[A]
2F7P[A]
2F7Q[A]
2F7R[A]
2FYV[A]
2OW6[A]
2OW7[A]
3BLB[A]
3BUB[A]
3BUD[A]
3BUI[A]
3BUP[A]
3BUQ[A]
3BVT[A]
3BVU[A]
3BVV[A]
3BVW[A]
3BVX[A]
3CV5[A]
3CZN[A]
3CZS[A]
3D4Y[A]
3D4Z[A]
3D50[A]
3D51[A]
3D52[A]
3DDF[A]
3DDG[A]
3DX0[A]
3DX1[A]
3DX2[A]
3DX3[A]
3DX4[A]
3EJP[A]
3EJQ[A]
3EJR[A]
3EJS[A]
3EJT[A]
3EJU[A]
 lysosomal α-mannosidase (LManII;dLM408;CG6206;Dmel_CG6206) 3.2.1.24 Drosophila melanogaster AAD38576.1
AAF52958.1
AAF52958.2
AAN10754.1
NP_609408.1
NP_723591.1
Q8IPB7
Q9VKV1
cryst
 CG9463   Drosophila melanogaster AAL48871.2
AAF52708.2
AAL48871.1
AHN54276.1
NP_609250.2
Q8SYY1
Q9VLI2
 
 CG9465   Drosophila melanogaster AAF52709.2
AAF52709.1
NP_609251.1
Q9VLI1  
 CG9466   Drosophila melanogaster AAF52710.1
AAL13500.1
AHN54277.1
NP_609252.1
Q9VLI0  
 CG9468   Drosophila melanogaster AAM50967.1
AAF52711.2
AGW25603.1
NP_609253.1
Q8MS44
Q9VLH9
 
 CG5322   Drosophila melanogaster AAF52957.1
ABC86349.1
AGB92885.1
NP_609407.1
Q9VKV2  
 ORF (fragment)   Equus caballus AEB61005.1    
 Ecym_3349   Eremothecium cymbalariae DBVPG#7215 AET38837.1    
 AGR385C   Eremothecium gossypii ATCC 10895 AAS54875.1
AAS54875.2
Q74Z21  
 FAGOS_FAGR385C   Eremothecium gossypii FDAG1 AEY99207.1    
 AW171_hschr42395   Eremothecium sinecaudum ATCC 58844 AMD20502.1    
 AMAN, partial (fragment)   Evaniella sp. 192 ASN78168.1    
 AMAN, partial (fragment)   Evaniella sp. 206 ASN78171.1    
 AMAN, partial (fragment)   Evaniella sp. 230 ASN78174.1    
 AMAN, partial (fragment)   Evaniella sp. 234 ASN78177.1    
 AMAN, partial (fragment)   Evaniella sp. 237 ASN78179.1    
 AMAN, partial (fragment)   Evaniella sp. 485 ASN78200.1    
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