Glycoside Hydrolase Family 38

Activities in Familyα-mannosidase (EC 3.2.1.24); mannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide α-1,3-1,6-mannosidase (EC 3.2.1.114); α-2-O-mannosylglycerate hydrolase (EC 3.2.1.170); mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 7
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorNot known
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6683); Uniprot accession (536); PDB accession (75); 3D entries (8); cryst (2)
All (6282) Archaea (74) Bacteria (5655) Eukaryota (552) unclassified (1) Structure (8 - 2 cryst) Characterized (44)
| 1 | 2 | 3 | 4 | 5 | 6 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AMAN, partial (fragment)   Acanthinevania sp. 240 ASN78182.1    
 AMAN, partial (fragment)   Acanthinevania sp. 242 ASN78183.1    
 AMAN, partial (fragment)   Acanthinevania sp. 271 ASN78185.1    
 AMAN, partial (fragment)   Acanthinevania sp. 289 ASN78192.1    
 AMAN, partial (fragment)   Acanthinevania sp. 292 ASN78194.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56101.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56315.1    
 ALNC14_000460 (Alnc14c1g41)   Albugo laibachii Nc14 CCA13903.1    
 AMAN, partial (fragment)   Alobevania gattiae ASN78169.1    
 CB5_LOCUS23745   Ananas comosus var. bracteatus VUW73160.1
CAB5275435.1
   
 ACCB07842 (fragment)   Apis cerana AEY60223.1    
 ACCB09944 (fragment)   Apis cerana AEY60742.1    
 Aa1_7515 (fragment)   Arabidopsis arenosa CARE-1 AAR15492.1 Q6V5C5  
 α-mannosidase (LMann;AtLMann;At3g26720)   Arabidopsis thaliana AAK62592.1
AAM47314.1
AEE77203.1
AEE77204.1
AIX48006.1
ANM65468.1
ANM65469.1
ANM65470.1
BAB01735.1
BAH56863.1
CAA66821.1
CAA72432.1
NP_189306.1
P94078  
 At5g13980   Arabidopsis thaliana AAN15620.1
AAM20555.1
AED91968.1
AED91969.1
AED91970.1
BAB11126.1
BAD93831.1
BAD94717.1
NP_196902.1
Q8LPJ3
Q9FFX7
 
 At5g66150/K2A18.23   Arabidopsis thaliana BAB10420.1
AED98165.1
ANM70390.1
ANM70391.1
NP_201416.1
Q9FKW9  
 α-mannosidase II (AtGMII;At5g14950) 3.2.1.114 Arabidopsis thaliana CAC01814.1
AAK96611.1
AAL38616.1
AAY90120.1
AED92095.1
CAH33905.1
CBA12844.1
CBA34884.1
NP_196999.1
Q940T6
Q9LFR0
 
 DS421_16g551660   Arachis hypogaea QHN87055.1    
 DS421_20g704770   Arachis hypogaea QHN83439.1    
 DS421_16g551630   Arachis hypogaea QHN87050.1
QHN87051.1
QHN87052.1
   
 DS421_3g88740 (fragment)   Arachis hypogaea QHO58206.1    
 DS421_1g08400   Arachis hypogaea QHO48790.1    
 DS421_18g634030   Arachis hypogaea QHN98206.1    
 DS421_6g193940   Arachis hypogaea QHO47157.1
QHO47158.1
   
 DS421_6g191010 (fragment)   Arachis hypogaea QHO46828.1    
 DS421_6g193920   Arachis hypogaea QHO47155.1    
 DS421_8g251870   Arachis hypogaea QHO32681.1    
 DS421_5g137110   Arachis hypogaea QHO40396.1    
 DS421_10g309020   Arachis hypogaea QHO17063.1    
 DS421_11g330550 (fragment)   Arachis hypogaea QHO19617.1    
 DS421_11g317970   Arachis hypogaea QHO18130.1    
 EGX52778.1   Arthrobotrys oligospora ATCC 24927 EGX52778.1    
 ORF   Ascaris suum ADY40773.1    
 ORF   Ascaris suum ADY40800.1    
 ORF   Ascaris suum ADY41578.1    
 ORF   Ascaris suum ADY40731.1    
 ORF (fragment)   Ascaris suum ADY40786.1    
 ORF (fragment)   Ascaris suum ADY46025.1    
 ORF (fragment)   Ascaris suum ADY48332.1    
 mannosidase II (AfAms1)   Aspergillus fumigatus YJ-407 AAW49442.1 Q5I5K3  
 AN2936.2   Aspergillus nidulans FGSC A4 EAA63507.1 Q5B944  
 α-mannosidase   Aspergillus nidulans T222 AAB70514.1 O13344  
 An02g11720   Aspergillus niger CBS 513.88 CAK37873.1 A2QEN9  
 AO090005001458   Aspergillus oryzae RIB40 BAE56379.1 Q2UPY6  
 ORF (fragment)   Belgica antarctica ABF72867.1    
 BGT96224V316_LOCUS5746   Blumeria graminis f. sp. tritici VDB90689.1    
 α-mannosidase (Man2B1;ManB) (lysosomal) 3.2.1.24 Bos taurus AAC48763.1
AAB67726.2
NP_776986.2
Q29451 1O7D[A,B,C,D,E]
 α-mannosidase 3.2.1.24 Bos taurus AAE61905.1    
 Unknown (protein for MGC:127782) (fragment)   Bos taurus HEREFORD AAI05161.1 A8YXY9  
 BCIN_01g03390 (Bcams1)   Botrytis cinerea B05.10 ATZ45577.1    
 BCIN_01g03390 (Bcams1)   Botrytis cinerea B05.10 ATZ45578.1    
 glycoside hydrolase family 38 protein (Bofut4_p162000.1)   Botrytis cinerea T4 CCD54911.1    
 AMAN, partial (fragment)   Brachygaster sp. 286 ASN78190.1    
 BOLC1T03902H (fragment)   Brassica oleracea VDD51513.1    
 BOLC7T44095H (fragment)   Brassica oleracea VDD38535.1    
 BOLC9T54089H   Brassica oleracea VDD28766.1    
 BOLC3T13232H   Brassica oleracea VDC86210.1    
 BOLC3T13286H   Brassica oleracea VDC86313.1    
 BOLC2T06672H   Brassica oleracea VDD19338.1    
 BRAA06T27098Z   Brassica rapa VDC68558.1    
 BRAA09T36657Z   Brassica rapa VDC59046.1    
 BRAA02T05252Z   Brassica rapa VDC85342.1    
 BRAA03T10011Z   Brassica rapa VDC78793.1    
 BRAA03T09963Z   Brassica rapa VDC78745.1    
 p075G11_ORF1 (fragment)   Cadophora finlandica ACP19537.1 C3VES8  
 α-mannosidase (Aman-3;F48C1.1) 3.2.1.24 Caenorhabditis elegans Bristol N2 AAB52345.2
AAM81094.1
CCD62468.1
NP_491568.1
NP_740847.1
NP_740848.1
O01574  
 α-mannosidase (Aman-1;F55D10.1) (lysosomal) 3.2.1.24 Caenorhabditis elegans Bristol N2 AAA81731.2
CCD67087.1
NP_508811.1
Q20829  
 α-mannosidase II (Aman-2;F58H1.1) 3.2.1.114 Caenorhabditis elegans Bristol N2 CAJ55257.1
CAB00104.1
CAH33906.1
CBA12845.1
CBA34885.1
NP_505995.1
Q21010
Q2PJ74
 
 MAN2B1-like protein (fragment)   Callithrix jacchus ABQ22594.1 A6MKK3  
 ORF (fragment)   Callorhinchus milii AFO94440.1    
 ORF (fragment)   Callorhinchus milii AFO95698.1    
 ORF (fragment)   Callorhinchus milii AFP02963.1    
 α-1,2/3/6-mannosidase (JBM;JBAM) (peptide sequencing) (partial) 3.2.1.113
3.2.1.114
3.2.1.24
Canavalia ensiformis   C0HJB3 6B9O[A,B]
6B9P[A,B]
 CAALFM_C402360WA (Ams1)   Candida albicans SC5314 AOW29006.1    
 CJI96_0001257   [Candida] auris B11220 QEO20448.1    
 CJJ09_003638   [Candida] auris B11245 QEL61492.1    
 CD36_42240   Candida dubliniensis CD36 CAX42104.1 B9WFT5  
 GVI51_E04873   [Candida] glabrata ATCC 2001 QHS65550.1    
 CAGL0E05148g   [Candida] glabrata CBS 138 CAG58831.1 Q6FV32  
 SAMEA4029010_CIC11G00000003298   [Candida] intermedia CBS 141442 SGZ56892.1    
 SAMEA4029009_CIC11G00000004730   [Candida] intermedia PYCC 4715 SGZ57524.1    
 CORT_0B00490   Candida orthopsilosis Co 90-125 CCG21770.1    
 CPAR2_500360   Candida parapsilosis CDC317 CCE43810.1    
 lysosomal α-mannosidase (Man2b1;LAM;chLAM) 3.2.1.24 Capra hircus AEZ02307.1    
 Golgi α-mannosidase II   Capra hircus AHD46138.1    
 ORF (fragment)   Capsella grandiflora ADG39048.1 D6PRR6  
 ORF (fragment)   Capsella grandiflora ADG39049.1 D6PRR7  
 ORF (fragment)   Capsella grandiflora ADG39051.1 D6PRR9  
 ORF (fragment)   Capsella rubella AEN83007.1    
 ORF (fragment)   Capsella rubella AEN83012.1    
 α-mannosidase (α-Man) 3.2.1.24 Capsicum annuum ADU20406.1    
 α-mannosidase (ManB;LMann;CpLMann) (lysosomal) 3.2.1.24 Cavia porcellus AAL58982.1
AIX48009.1
Q8VHC8  
 A3770_18p82200   Chloropicon primus CCMP1205 QDZ25702.1    
 A3770_18p82210   Chloropicon primus CCMP1205 QDZ25703.1    
 unnamed protein product   Ciona intestinalis CAH33907.1
CBA12846.1
CBA34886.1
   
 EJF14_60265   Clavispora lusitaniae P1 QFZ29752.1    
 EJF16_60265   Clavispora lusitaniae P2 QFZ35402.1    
 EJF15_60265   Clavispora lusitaniae P3 QFZ41096.1    
 EJF17_60265   Clavispora lusitaniae P4 QFZ52442.1    
 EJF18_60265   Clavispora lusitaniae P5 QFZ46777.1    
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