Glycoside Hydrolase Family 37

Activities in Familyα,α-trehalase (EC 3.2.1.28).
Mechanism Inverting
ClanGH-G
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorAsp (inferred)
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4965); Uniprot accession (511); PDB accession (8); 3D entries (2); cryst (0)
All (4701) Archaea (3) Bacteria (3949) Eukaryota (746) unclassified (3) Structure (2) Characterized (42)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 trehalase   Holothuria leucospilota AWJ64279.1    
 trehalase (TreA;TreH) 3.2.1.28 Homo sapiens BAA24381.1
AAB50778.1
AAI09207.1
ABA67142.1
BAD96860.1
BAD96863.1
BAG52455.1
NP_009111.1
O43280  
 ORF   Hypocrella siamensis MTCC 10142 ANH56448.1    
 KAFR_0C00760 (Kafr0c00760)   Kazachstania africana CBS 2517 CCF57071.1    
 KNAG_0J01120 (Knag0j01120)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK72194.1    
 neutral trehalase (Nth1) 3.2.1.28 Kluyveromyces lactis CAA57181.1 P49381  
 neutral trehalase (TreA;KLLA0E17325g) 3.2.1.28 Kluyveromyces lactis NRRL Y-1140 CAG99815.1 P49381  
 KLMA_60117   Kluyveromyces marxianus DMKU3-1042 BAO41408.1    
 KMAR_60117   Kluyveromyces marxianus NBRC 1777 BAP72856.1    
 ATY40_BA7504491 (Nth1)   Komagataella pastoris ATCC 28485 ANZ77561.1    
 AT249_GQ6705209 (Nth1)   Komagataella phaffii ATCC 76273 AOA64540.1    
 PP7435_Chr4-0135 (Ntp1)   Komagataella phaffii CBS 7435 CCA40310.1
SOP83061.1
   
 PAS_chr4_0816   Komagataella phaffii GS115 CAY72087.1
AOA70049.1
C4R912  
 KLTH0G16434g   Lachancea thermotolerans CBS 6340 CAR25312.1    
 glycoside hydrolase 37   Lagenidium giganteum ARSEF 373 AOW41677.1    
 trehalase (soluble)   Laodelphax striatella AFL03409.1    
 trehalase (membrane-bound)   Laodelphax striatella AFL03410.1    
 trehalase 1a (fragment)   Laparus doris ADT64093.1    
 trehalase 1a (Tre1A)   Leptinotarsa decemlineata AOT99587.1    
 neutral trehalase (Nth1;Lema_p001160.1)   Leptosphaeria maculans JN3 AAM92143.1
AAM92145.1
CBY01329.1
Q8NJR8
Q8NJR9
 
 ORF (fragment)   Leptosphaeria maculans JN3 CBX90798.1 E4ZHG5  
 LRAMOSA06251   Lichtheimia ramosa CDS14080.1    
 LRAMOSA04644   Lichtheimia ramosa CDS12450.1    
 LRAMOSA01097   Lichtheimia ramosa CDS03696.1    
 LRAMOSA01762   Lichtheimia ramosa CDS07813.1    
 LRAMOSA01872   Lichtheimia ramosa CDS07923.1    
 trehalase (Tre) (soluble)   Locusta migratoria ACP28173.1    
 trehalase   Locusta migratoria AQV08186.1    
 trehalase   Locusta migratoria AQV08187.1    
 trehalase   Locusta migratoria AQV08185.1    
 trehalase 2, partial (fragment)   Ludisia discolor ATP75364.1    
 trehalase 1, partial (fragment)   Ludisia discolor ATP75362.1    
 trehalase, partial (fragment)   Macrosiphum euphorbiae AGG35943.1    
 trehalase 3.2.1.28 Magnaporthe grisea 4091-5-8 AAB88889.1 O42622  
 trehalase (Tre1)   Magnaporthe grisea GUY11 AAN38003.1 Q8J0H8  
 neutral trehalase (NTH1) 3.2.1.28 Magnaporthe grisea GUY11 AAN46743.1 O42622  
 neutral trehalase (NTH1;MG09471.4) 3.2.1.28 Magnaporthe oryzae 70-15 EAA53721.1
XP_364626.1
O42622  
 MGG_01261   Magnaporthe oryzae 70-15 XP_003714173.1
EAA55610.1
XP_363335.1
   
 MSYG_4058   Malassezia sympodialis ATCC 42132 SHO79708.1    
 trehalase (Tre1) (fragment)   Medicago truncatula CAB50901.1 Q9XGH9  
 trehalase (Tre1) (fragment)   Medicago truncatula ABJ98545.1 A0FJ30  
 BN887_05325   Melanopsichium pennsylvanicum 4 CDI52344.1    
 neutral trehalase (Ntl) 3.2.1.28 Metarhizium acridum CQM102 AAS67888.1
AAS67889.1
Q6Q5X7  
 neutral trehalase (NTL) 3.2.1.28 Metarhizium anisopliae var. anisopliae 2575 AAT68667.1 Q9HDE9  
 neutral trehalase (Nthi;Ntl1) 3.2.1.28 Metarhizium anisopliae var. anisopliae ME1 CAC17620.1
CAC17619.1
Q9HDE9  
 neutral trehalase (NTL) (partial)   Metarhizium anisopliae var. anisopliae SCB2-2I AAQ75556.1 Q6UDD9  
 neutral trehalase (fragment)   Metarhizium anisopliae var. anisopliae SDA21III AAT68668.1 Q6DWJ4  
 neutral trehalase (NTL) (partial)   Metarhizium anisopliae var. anisopliae SHB1-2I AAQ75555.1 Q6UDE0  
 neutral trehalase (NTL) (fragment)   Metarhizium majus 473 AAQ75557.1    
 MICPUN_82031   Micromonas commoda sp. RCC299 ACO63482.1 C1E6R9  
 GNLVRS01_PISO0N23465g (Piso0_005827)   Millerozyma farinosa CBS 7064 CCE87280.1    
 GNLVRS01_PISO0M23178g (Piso0_005827)   Millerozyma farinosa CBS 7064 CCE86171.1    
 trehalase1 (Tre1)   Moniliella megachiliensis SN 124A BAO72961.1    
 trehalase2 (Tre2)   Moniliella megachiliensis SN 124A BAO72962.1    
 trehalase 3.2.1.28 Mus musculus AAF61430.1
AAH19214.1
AAK97631.1
AAT24328.1
BAB25963.1
NP_067456.1
Q8VCS8
Q9JLT2
 
 ORF (fragment)   Musca domestica ALHF AFP65169.1    
 NCAS_0E01490 (Ncas0e01490)   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC70219.1    
 NDAI_0L01670 (Ndai0l01670)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD27652.1
CCD25944.2
   
 trehalase, partial (fragment)   Neocloeon triangulifer AWM98353.1    
 trehalase (TreB) 3.2.1.28 Neurospora crassa AAC01744.1 O42783
O42783
 
 NCU04221.1 (TreB)   Neurospora crassa OR74A EAA31609.1
CAD36994.1
XP_323561.1
O42783  
 NCU00943.1   Neurospora crassa OR74A EAA35900.1
XP_325123.1
Q7SGH9  
 trehalase (Tre;NtTRE)   Nicotiana tabacum BAI63261.1 D2KWM9  
 unnamed protein product (fragment)   Nicotiana tabacum CAB69263.1    
 soluble trehalase, partial (Tre-1) (fragment)   Nilaparvata bakeri AGE93914.1    
 membrane-bound trehalase, partial (Tre-2)   Nilaparvata bakeri AGE93907.1    
 trehalase (Tre-1) (soluble) 3.2.1.28 Nilaparvata lugens ACN85420.1
AGE93908.1
AGE93909.1
AGE93910.1
AGE93911.1
AGE93912.1
APA33854.1
C0LZJ6  
 trehalase (Tre-2) (membrane-bound)   Nilaparvata lugens ACN85421.1
ACV20872.1
AGE93901.1
AGE93902.1
AGE93903.1
AGE93904.1
AGE93905.1
C0LZJ7  
 soluble trehalase 1-2, partial   Nilaparvata lugens AQT25642.1    
 membrane-bound trehalase, partial (Tre-2)   Nilaparvata muiri AGE93906.1    
 soluble trehalase, partial (Tre-1) (fragment)   Nilaparvata muiri AGE93913.1    
 trehalase 2 (Treh-2)   Omphisa fuscidentalis ABO20845.1 A3RLQ4  
 trehalase 1 (Treh-1) 3.2.1.28 Omphisa fuscidentalis ABO20846.1 A3RLQ5  
 trehalase (TreH;TreA) 3.2.1.28 Oryctolagus cuniculus AAA63460.1 P19813  
 Os10g0521000   Oryza sativa Japonica Group AAG13442.1
AAP54665.1
ABB47896.1
BAF27001.1
BAG98305.1
BAT11704.1
Q9FWC1  
 OSTLU_38852   Ostreococcus lucimarinus CCE9901 ABO96389.1 A4RY23  
 Ot05g04440   Ostreococcus tauri OTTH0595 CAL54199.1 Q018H6  
 membrane-bound trehalase   Ostrinia furnacalis ANY30159.1    
 soluble trehalase   Ostrinia furnacalis ANY30160.1    
 ORF (fragment)   Papilio xuthus BAM18585.1    
 ORF (short fragment)   Papilio xuthus BAM19855.1    
 Pc22g03670   Penicillium rubens Wisconsin 54-1255 CAP97655.1 B6HRS3  
 ORF (fragment)   Phlebotomus arabicus ACS93489.1 C6FFT7  
 trehalase   Physcomitrella patens subsp. patens ABO61746.1 A6MIZ4  
 WS0285_I07   Picea sitchensis ABR17991.1 B8LQR1  
 C5L36_0D01960   Pichia kudriavzevii CBS573 AWU77452.1    
 trehalase (Tre1)   Pimpla hypochondriaca CAD31109.1 Q8MMG9  
 unnamed protein product   Podospora anserina S mat+ CAP59879.1
CDP22522.1
B2A9W9  
 unnamed protein product   Podospora anserina S mat+ CAP73650.1
CDP26053.1
B2B772  
 TreH / PvTreH   Polypedilum vanderplanki BAH28889.1 C9K4M8  
 ORF   Pristhesancus plagipennis ATU82952.1    
 trehalase (fragment)   Rattus norvegicus AAC25985.1 O70282  
 acid trehalase   Rhizoctonia solani AGM46811.1    
 neutral trehalase   Rhizoctonia solani AGM46812.1    
 neutral trehalase (Nth1)   Rhizophagus intraradices AAX19736.1    
 RHTO0S_03e04346g   Rhodotorula toruloides CECT1137 CDR38136.1    
 EC1118_1D0_2388g   Saccharomyces cerevisiae EC1118 Lalvin EC1118 CAY78509.1 C8Z4S0  
 EC1118_1B15_1310g   Saccharomyces cerevisiae EC1118 Lalvin EC1118 CAY77786.1 C8Z3Z7  
 neutral trehalase 1 (Nth1;Nth;YDR001c;YD8119.07c) 3.2.1.28 Saccharomyces cerevisiae S288c AAV19867.1
AAA66896.1
AAN20051.1
CAA46718.1
CAA88061.1
NP_010284.1
P32356
Q05216
5JTA[A]
5M4A[A]
5N6N[C]
5NIS[A]
 neutral trehalase 2 (Nth2;YBR001c;YBR0106) 3.2.1.28 Saccharomyces cerevisiae S288c CAA81270.1
CAA84937.1
NP_009555.1
P35172  
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