Activities in Family	α,α-trehalase (EC 3.2.1.28);
Mechanism	Inverting a
Clan	GH-G
3D Structure Status	( α / α ) 6 barrel
Catalytic Nucleophile/Base	Glu (inferred)
Catalytic Proton Donor	Asp (inferred)
External resources	CAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (12004); Uniprot accession (46); PDB accession (13); 3D entries (4); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
CGB_G6010C		Cryptococcus gattii WM276	ADV23702.1
IAS59_004495		Cryptococcus gattii WM276	WVQ90714.1
IAS59_002776		Cryptococcus gattii WM276	WVQ89029.1
5258		Cryptococcus neoformans var neoformans JEC21 (Cryne_JEC21_1)
2548		Cryptococcus neoformans var neoformans JEC21 (Cryne_JEC21_1)
CNAG_03525		Cryptococcus neoformans var. grubii H99	AFR96750.1 AFR96750.2
neutral trehalase (Nth1;CNAG_03785)		Cryptococcus neoformans var. grubii H99	DAA05786.1 AFR93292.1 AFR93292.2
3157		Cryptococcus neoformans H99 (Cryne_H99_1)
3392		Cryptococcus neoformans H99 (Cryne_H99_1)
CKF44_003146		Cryptococcus neoformans var. grubii KN99	AUB26705.1
CKF44_003376		Cryptococcus neoformans var. grubii KN99	AUB22814.1
neutral trehalase 2 (NTH2;CNG00690)	3.2.1.28	Cryptococcus neoformans var. neoformans JEC21	AAW44482.1 AAW44482.2	Q5KEF4
neutral trehalase 1 (NTH1;CNB02790)	3.2.1.28	Cryptococcus neoformans var. neoformans JEC21	AAW41560.1	Q5KM64
LQV05_005868		Cryptococcus neoformans VNII	UOH83153.1
LQV05_004127		Cryptococcus neoformans VNII	UOH81456.1
IAR50_001198		Cryptococcus sp. DSM 104548	WVQ71658.1
IAR50_001601		Cryptococcus sp. DSM 104548	WVQ72057.1
IAT38_000390		Cryptococcus sp. DSM 104549	WVQ78305.1
IAT38_001841		Cryptococcus sp. DSM 104549	WVQ79741.1
trehalase		Culex pipiens pallens	AVZ46656.1 AZK90231.1
168152		Cunninghamella echinulata NRRL 1382 v1.0 (Cunech1)
265456		Cunninghamella echinulata NRRL 1382 v1.0 (Cunech1)
243694		Cunninghamella echinulata NRRL 1382 v1.0 (Cunech1)
270542		Cunninghamella echinulata NRRL 1382 v1.0 (Cunech1)
yc1106_00753		Curvularia clavata yc1106	USP73479.1
yc1106_06222		Curvularia clavata yc1106	USP78948.1
trehalase (Tre;ClTre)		Curvularia lunata	ADX41482.1
CcaverHIS002_0310620 (fragment)		Cutaneotrichosporon cavernicola HIS002	BEI83194.1
CcaverHIS002_0202970 (Nth1)		Cutaneotrichosporon cavernicola HIS002	BEI81137.1
CcaverHIS019_0202970 (Nth1)		Cutaneotrichosporon cavernicola HIS019	BEI88935.1
CcaverHIS019_0310480 (fragment)		Cutaneotrichosporon cavernicola HIS019	BEI90978.1
CcaverHIS631_0310550 (fragment)		Cutaneotrichosporon cavernicola HIS631	BEI98756.1
CcaverHIS631_0203010 (Nth1)		Cutaneotrichosporon cavernicola HIS631	BEI96712.1
CcaverHIS641_0310500 (fragment)		Cutaneotrichosporon cavernicola HIS641	BEJ06528.1
CcaverHIS641_0203010 (Nth1)		Cutaneotrichosporon cavernicola HIS641	BEJ04484.1
CspHIS471_0202980 (Nth1)		Cutaneotrichosporon sp. HIS471	BEJ11838.1
CspHIS471_0312020 (fragment)		Cutaneotrichosporon sp. HIS471	BEJ14028.1
CYME_CMH100C		Cyanidioschyzon merolae strain 10D	BAM79781.1
CYME_CMN097C		Cyanidioschyzon merolae strain 10D	BAM81219.1
1426998		Cyathus striatus AH 40144 v2.0 (Cyastr2)
1401618		Cyathus striatus AH 40144 v2.0 (Cyastr2)
CYFA0S_09e02674g		Cyberlindnera fabianii YJS4271	CDR42396.1
455453		Cylindrobasidium torrendii FP15055 ss-10 (Cylto1)
401054		Cylindrobasidium torrendii FP15055 ss-10 (Cylto1)
322962		Cylindrocarpon olidum MPI-CAGE-CH-0241 v1.0 (Cylol1)
2198		Cylindrocarpon olidum MPI-CAGE-CH-0241 v1.0 (Cylol1)
120534		Cyphellophora europaea CBS 101466 (Cypeu1)
CTOB1V02_LOCUS13781 (fragment)		Cyprideis torosa	CAD7235966.1
CTOB1V02_LOCUS1726 (fragment)		Cyprideis torosa	CAD7223746.1
CTOB1V02_LOCUS14630 (fragment)		Cyprideis torosa	CAD7236815.1
CTOB1V02_LOCUS15830 (fragment)		Cyprideis torosa	CAD7238015.1
165972		Rhodotorula minuta MCA 4210 (Rhomi1)
173604		Rhodotorula minuta MCA 4210 (Rhomi1)
1400581		Cytidiella melzeri FP 102339 v1.0 (Cytmel1)
695395		Cytidiella melzeri FP 102339 v1.0 (Cytmel1)
309492		Dactylonectria estremocensis MPI-CAGE-AT-0021 (Daces1)
616651		Dactylonectria estremocensis MPI-CAGE-AT-0021 (Daces1)
476308		Dactylonectria macrodidyma MPI-CAGE-AT-0147 v1.0 (Dacma1)
760253		Dactylonectria macrodidyma MPI-CAGE-AT-0147 v1.0 (Dacma1)
trehalase 2.1, partial (fragment)		Dactylorhiza majalis	ATP75361.1
trehalase 1.1, partial (fragment)		Dactylorhiza majalis	ATP75363.1
trehalase 2.2, partial (fragment)		Dactylorhiza majalis	ATP75360.1
560230		Daldinia bambusicola CBS 122872 v1.0 (Dalba1)
545420		Daldinia bambusicola CBS 122872 v1.0 (Dalba1)
451241		Daldinia caldariorum CBS 122874 v1.0 (Dalcal1)
451167		Daldinia caldariorum CBS 122874 v1.0 (Dalcal1)
581		Daldinia decipiens CBS 113046 v1.0 (Daldec1)
358006		Daldinia decipiens CBS 113046 v1.0 (Daldec1)
394157		Daldinia eschscholtzii FL0578 v1.0 (Dales1)
416673		Daldinia eschscholtzii FL0578 v1.0 (Dales1)
451625		Daldinia grandis CBS 114736 v1.0 (Dalgra1)
425222		Daldinia grandis CBS 114736 v1.0 (Dalgra1)
481597		Daldinia loculata AZ0526 v2.0 (DallocAZ0526_2)
445913		Daldinia loculata AZ0526 v2.0 (DallocAZ0526_2)
354410		Daldinia loculata CBS 113971 v1.0 (Dalloc1)
331835		Daldinia loculata CBS 113971 v1.0 (Dalloc1)
340146		Daldinia sp. FL1419 v1.0 (DaFL1419_1)
308694		Daldinia sp. FL1419 v1.0 (DaFL1419_1)
134572		Daldinia vernicosa CBS 139.73 v1.0 (Dalver1)
246524		Daldinia vernicosa CBS 139.73 v1.0 (Dalver1)
DSTB1V02_LOCUS14275 (fragment)		Darwinula stevensoni	CAD7254529.1
DSTB1V02_LOCUS9112		Darwinula stevensoni	CAD7249314.1
DSTB1V02_LOCUS9112		Darwinula stevensoni	CAD7249314.1
DCAR_0311316		Daucus carota subsp. sativus	WOG92059.1
741		Debaryomyces hansenii CBS767 (Debha1)
DEHA0B02673g		Debaryomyces hansenii CBS767	CAG85070.1
47850		Dekkera bruxellensis CBS 2499 (Dekbr2)
trehalase (TRE;DaTRE)		Delia antiqua	AHN49714.1
447613		Delitschia confertaspora ATCC 74209 v1 (Delco1)
374678		Delphinella strobiligena CBS 735.71 v1.0 (Delst1)
unknown		Dendroctonus ponderosae	AEE63287.1
870540		Dendrothele bispora CBS 962.96 v1 (Denbi1)
855300		Dendrothele bispora CBS 962.96 v1 (Denbi1)
554109		Dendryphion nanum MPI-CAGE-CH-0243 (Denna1)
602464		Dendryphion nanum MPI-CAGE-CH-0243 (Denna1)
268254		Dendryphion nanum MPI-CAGE-CH-0243 (Denna1)
DIABBA_ LOCUS 5330		Diabrotica balteata	CAG9831767.1
DIABBA_ LOCUS 5332		Diabrotica balteata	CAG9831769.1
DIABBA_ LOCUS 5329		Diabrotica balteata	CAG9831766.1
DIABBA_ LOCUS 5331 (fragment)		Diabrotica balteata	CAG9831768.1
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