Glycoside Hydrolase Family 37

Activities in Familyα,α-trehalase (EC 3.2.1.28).
Mechanism Inverting
ClanGH-G
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorAsp (inferred)
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (8452); Uniprot accession (511); PDB accession (10); 3D entries (3); cryst (0)
All (8176) Archaea (4) Bacteria (7242) Eukaryota (926) unclassified (4) Structure (3) Characterized (42)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Treh-1A (fragment)   Heliconius numata silvana AEN67864.1    
 Treh-1A (fragment)   Heliconius numata silvana AEN67867.1    
 Treh-1A (fragment)   Heliconius numata silvana AEN67868.1    
 Treh-1A (fragment)   Heliconius numata silvana AEN67869.1    
 Treh-1A (fragment)   Heliconius numata silvana AEN67870.1    
 Treh-1A (fragment)   Heliconius numata silvana AEN67872.1    
 Treh-1A (fragment)   Heliconius numata silvana AEN67874.1    
 ORF (fragment)   Heliconius pachinus ACY09221.1 D0VJR2  
 ORF (fragment)   Heliconius pachinus ACY09222.1 D0VJR3  
 ORF (fragment)   Heliconius pachinus ACY09224.1 D0VJR5  
 trehalase 1a (fragment)   Heliconius sara ADT64095.1    
 soluble trehalase (HaTreh-1)   Helicoverpa armigera AJK29979.1    
 membrane-bound trehalase (HaTreh-2)   Helicoverpa armigera AJK29980.1    
 soluble trehalase   Helicoverpa armigera QGV10794.1    
 trehalase-2   Heortia vitessoides AYO46921.1    
 trehalase-1, partial   Heortia vitessoides AZM68711.1    
 trehalase, partial (fragment)   Hipposideros armiger QED12475.1    
 trehalase   Holothuria leucospilota AWJ64279.1    
 trehalase (TreA;TreH) 3.2.1.28 Homo sapiens BAA24381.1
AAB50778.1
AAI09207.1
ABA67142.1
BAD96860.1
BAD96863.1
BAG52455.1
NP_009111.1
O43280  
 ORF   Hypocrella siamensis MTCC 10142 ANH56448.1    
 KAFR_0C00760 (Kafr0c00760)   Kazachstania africana CBS 2517 CCF57071.1    
 KNAG_0J01120 (Knag0j01120)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK72194.1    
 neutral trehalase (Nth1) 3.2.1.28 Kluyveromyces lactis CAA57181.1 P49381  
 KDRO_E03700   Kluyveromyces lactis CBS 2105 QEU61492.1    
 KDRO_E03700   Kluyveromyces lactis CBS 2105 QEU61492.1    
 neutral trehalase (TreA;KLLA0E17325g) 3.2.1.28 Kluyveromyces lactis NRRL Y-1140 CAG99815.1 P49381  
 FIM1_4181   Kluyveromyces marxianus CBS4857 QGN17447.1    
 KLMA_60117   Kluyveromyces marxianus DMKU3-1042 BAO41408.1    
 KMAR_60117   Kluyveromyces marxianus NBRC 1777 BAP72856.1    
 ATY40_BA7504491 (Nth1)   Komagataella pastoris ATCC 28485 ANZ77561.1    
 AT249_GQ6705209 (Nth1)   Komagataella phaffii ATCC 76273 AOA64540.1    
 PP7435_Chr4-0135 (Ntp1)   Komagataella phaffii CBS 7435 CCA40310.1
SOP83061.1
   
 PAS_chr4_0816   Komagataella phaffii GS115 CAY72087.1
AOA70049.1
C4R912  
 KLTH0G16434g   Lachancea thermotolerans CBS 6340 CAR25312.1    
 LSAL_LOCUS14646   Lactuca saligna CAB4086479.1    
 glycoside hydrolase 37   Lagenidium giganteum ARSEF 373 AOW41677.1    
 trehalase (soluble)   Laodelphax striatellus AFL03409.1    
 trehalase (membrane-bound)   Laodelphax striatellus AFL03410.1    
 trehalase 1a (fragment)   Laparus doris ADT64093.1    
 LSINAPIS_LOCUS10089   Leptidea sinapis VUY99202.1    
 LSINAPIS_LOCUS10089   Leptidea sinapis VUY99202.1    
 LSINAPIS_LOCUS15448   Leptidea sinapis VUZ06059.1    
 trehalase 1a (Tre1A)   Leptinotarsa decemlineata AOT99587.1    
 neutral trehalase (Nth1;Lema_p001160.1)   Leptosphaeria maculans JN3 AAM92143.1
AAM92145.1
CBY01329.1
Q8NJR8
Q8NJR9
 
 ORF (fragment)   Leptosphaeria maculans JN3 CBX90798.1 E4ZHG5  
 LRAMOSA06251   Lichtheimia ramosa CDS14080.1    
 LRAMOSA04644   Lichtheimia ramosa CDS12450.1    
 LRAMOSA01097   Lichtheimia ramosa CDS03696.1    
 LRAMOSA01762   Lichtheimia ramosa CDS07813.1    
 LRAMOSA01872   Lichtheimia ramosa CDS07923.1    
 trehalase (Tre) (soluble)   Locusta migratoria ACP28173.1    
 trehalase   Locusta migratoria AQV08186.1    
 trehalase   Locusta migratoria AQV08187.1    
 trehalase   Locusta migratoria AQV08185.1    
 trehalase 2, partial (fragment)   Ludisia discolor ATP75364.1    
 trehalase 1, partial (fragment)   Ludisia discolor ATP75362.1    
 trehalase, partial (fragment)   Macrosiphum euphorbiae AGG35943.1    
 DNF11_2962 (TreB)   Malassezia restricta CBS 7877 AYO43912.1    
 MRET_2528   Malassezia restricta KCTC 27527 AXA50767.1    
 MSYG_4058   Malassezia sympodialis ATCC 42132 SHO79708.1    
 Mp_1g10930   Marchantia polymorpha subsp. ruderalis Tak-1 BBM98111.1    
 Mp_2g20040   Marchantia polymorpha subsp. ruderalis Tak-1 BBN03021.1    
 trehalase (Tre1) (fragment)   Medicago truncatula CAB50901.1 Q9XGH9  
 trehalase (Tre1) (fragment)   Medicago truncatula ABJ98545.1 A0FJ30  
 BN887_05325   Melanopsichium pennsylvanicum 4 CDI52344.1    
 neutral trehalase (Ntl) 3.2.1.28 Metarhizium acridum CQM102 AAS67888.1
AAS67889.1
Q6Q5X7  
 neutral trehalase (NTL) 3.2.1.28 Metarhizium anisopliae var. anisopliae 2575 AAT68667.1 Q9HDE9  
 neutral trehalase (Nthi;Ntl1) 3.2.1.28 Metarhizium anisopliae var. anisopliae ME1 CAC17620.1
CAC17619.1
Q9HDE9  
 neutral trehalase (NTL) (partial)   Metarhizium anisopliae var. anisopliae SCB2-2I AAQ75556.1 Q6UDD9  
 neutral trehalase (fragment)   Metarhizium anisopliae var. anisopliae SDA21III AAT68668.1 Q6DWJ4  
 neutral trehalase (NTL) (partial)   Metarhizium anisopliae var. anisopliae SHB1-2I AAQ75555.1 Q6UDE0  
 G6M90_00g085570 (TreH)   Metarhizium brunneum 4556 QLI72277.1    
 G6M90_00g103760 (TreB)   Metarhizium brunneum 4556 QLI73487.1    
 neutral trehalase (NTL) (fragment)   Metarhizium majus 473 AAQ75557.1    
 METSCH_A04830 (Mpul0a04830)   Metschnikowia aff. pulcherrima APC 1.2 QBM85854.1    
 MICPUN_82031   Micromonas commoda sp. RCC299 ACO63482.1 C1E6R9  
 GNLVRS01_PISO0N23465g (Piso0_005827)   Millerozyma farinosa CBS 7064 CCE87280.1    
 GNLVRS01_PISO0M23178g (Piso0_005827)   Millerozyma farinosa CBS 7064 CCE86171.1    
 trehalase, partial (fragment)   Miniopterus fuliginosus QED12477.1    
 trehalase1 (Tre1)   Moniliella megachiliensis SN 124A BAO72961.1    
 trehalase2 (Tre2)   Moniliella megachiliensis SN 124A BAO72962.1    
 trehalase 3.2.1.28 Mus musculus AAF61430.1
AAH19214.1
AAK97631.1
AAT24328.1
BAB25963.1
NP_067456.1
Q8VCS8
Q9JLT2
 
 ORF (fragment)   Musca domestica ALHF AFP65169.1    
 trehalase, partial (fragment)   Myotis davidii QED12474.1    
 NCAS_0E01490 (Ncas0e01490)   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC70219.1    
 NDAI_0L01670 (Ndai0l01670)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD27652.1
CCD25944.2
   
 trehalase, partial (fragment)   Neocloeon triangulifer AWM98353.1    
 trehalase (TreB) 3.2.1.28 Neurospora crassa AAC01744.1 O42783
O42783
 
 NCU04221.1 (TreB)   Neurospora crassa OR74A EAA31609.1
CAD36994.1
XP_323561.1
O42783  
 NCU00943.1   Neurospora crassa OR74A EAA35900.1
XP_325123.1
Q7SGH9  
 trehalase (Tre;NtTRE)   Nicotiana tabacum BAI63261.1 D2KWM9  
 unnamed protein product (fragment)   Nicotiana tabacum CAB69263.1    
 soluble trehalase, partial (Tre-1) (fragment)   Nilaparvata bakeri AGE93914.1    
 membrane-bound trehalase, partial (Tre-2)   Nilaparvata bakeri AGE93907.1    
 trehalase (Tre-1) (soluble) 3.2.1.28 Nilaparvata lugens ACN85420.1
AGE93908.1
AGE93909.1
AGE93910.1
AGE93911.1
AGE93912.1
APA33854.1
C0LZJ6  
 trehalase (Tre-2) (membrane-bound)   Nilaparvata lugens ACN85421.1
ACV20872.1
AGE93901.1
AGE93902.1
AGE93903.1
AGE93904.1
AGE93905.1
C0LZJ7  
 soluble trehalase 1-2, partial   Nilaparvata lugens AQT25642.1    
 membrane-bound trehalase, partial (Tre-2)   Nilaparvata muiri AGE93906.1    
 soluble trehalase, partial (Tre-1) (fragment)   Nilaparvata muiri AGE93913.1    
 NYM_LOCUS29415 (fragment)   Nymphaea colorata VVW86072.1    
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