Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/Mexico/InDRE2664/2003	AVI15176.1
neuraminidase (NA)		Influenza A virus A/Mexico/InDRE499/2008	AVI15152.1
neuraminidase (NA)		Influenza A virus A/Mexico/JAL121/2011	AVI15197.1
neuraminidase (NA)		Influenza A virus A/Mexico/JAL25565/2009	AVI15164.1
neuraminidase (NA)		Influenza A virus A/Mexico/NHRC-OID_SAR30158N/2018	QBM07582.1
neuraminidase (NA)		Influenza A virus A/Mexico/NHRC-OID_SAR30160N/2018	QBM07593.1
neuraminidase (NA)		Influenza A virus A/Mexico/NHRC-OID_SAR30169N/2018	QBM07604.1
neuraminidase (NA)		Influenza A virus A/Mexico/NHRC-OID_SAR30184N/2018	QBM07619.1
neuraminidase (NA)		Influenza A virus A/Mexico/NHRC-OID_SAR30197N/2018	QBM07630.1
neuraminidase (NA)		Influenza A virus A/Mexico/OAX59/2012	AVI15121.1
neuraminidase (NA)		Influenza A virus A/Mexico/SAR30007N/2017	AXH81465.1
neuraminidase (NA)		Influenza A virus A/Mexico/SAR30012N/2017	AXH81477.1
neuraminidase (NA)		Influenza A virus A/Mexico/VER58/2012	AVI15110.1
neuraminidase (NA)		Influenza A virus A/Mexico/VER62/2012	AVI15128.1
neuraminidase (NA)		Influenza A virus A/Mexico/VER73/2012	AVI15088.1
neuraminidase (NA)		Influenza A virus A/Mexico/VER78/2012	AVI15099.1
neuraminidase (NA)		Influenza A virus A/Michigan/01/2019	QBM03808.1
neuraminidase (NA)		Influenza A virus A/Michigan/01/2021	UBR15543.1
neuraminidase (NA)		Influenza A virus A/Michigan/01/2022	UZO40605.1
neuraminidase (NA)		Influenza A virus A/Michigan/02/2021	UBR15567.1
neuraminidase (NA)		Influenza A virus A/Michigan/02/2022	UZO40629.1
neuraminidase (NA)		Influenza A virus A/Michigan/02/2022	UZO40617.1
neuraminidase (NA)		Influenza A virus A/Michigan/03/2022	UZO40641.1
neuraminidase (NA)		Influenza A virus A/Michigan/03/2022	UZO40651.1
neuraminidase (NA)		Influenza A virus A/Michigan/04/2022	UPP05993.1
neuraminidase (NA)		Influenza A virus A/Michigan/05/2021	UFQ22415.1
neuraminidase (NA)		Influenza A virus A/Michigan/05/2022	UPP06012.1 UPP06024.1
neuraminidase (NA)		Influenza A virus A/Michigan/06/2021	UXG52846.1
neuraminidase (NA)		Influenza A virus A/Michigan/06/2021	UXG52835.1
neuraminidase (NA)		Influenza A virus A/Michigan/06/2022	UPP06036.1
neuraminidase (NA)		Influenza A virus A/Michigan/07/2021	UXG52858.1
neuraminidase (NA)		Influenza A virus A/Michigan/07/2021	UXG52870.1
neuraminidase (NA)		Influenza A virus A/Michigan/07/2022	UPP06048.1
neuraminidase (NA)		Influenza A virus A/Michigan/08/2021	UXG52882.1
neuraminidase (NA)		Influenza A virus A/Michigan/08/2021	UXG52894.1
neuraminidase (NA)		Influenza A virus A/Michigan/08/2022	UPP06072.1
neuraminidase (NA)		Influenza A virus A/Michigan/09/2021	UJS43115.1
neuraminidase (NA)		Influenza A virus A/Michigan/09/2022	UPP06096.1
neuraminidase (NA)		Influenza A virus A/Michigan/10/2021	UJS43139.1
neuraminidase (NA)		Influenza A virus A/Michigan/10/2022	UPP04108.1
neuraminidase (NA)		Influenza A virus A/Michigan/100/2022	WES73540.1
neuraminidase (NA)		Influenza A virus A/Michigan/100/2022	WES73552.1
neuraminidase (NA)		Influenza A virus A/Michigan/101/2022	WES73564.1
neuraminidase (NA)		Influenza A virus A/Michigan/102/2022	WES73576.1
neuraminidase (NA)		Influenza A virus A/Michigan/103/2022	WES80644.1
neuraminidase (NA)		Influenza A virus A/Michigan/103/2022	WES80655.1
neuraminidase (NA)		Influenza A virus A/Michigan/11/2021	UJS43163.1
neuraminidase (NA)		Influenza A virus A/Michigan/11/2022	UXG51637.1
neuraminidase (NA)		Influenza A virus A/Michigan/11/2022	UXG52906.1
neuraminidase (NA)		Influenza A virus A/Michigan/12/2021	UJS43187.1
neuraminidase (NA)		Influenza A virus A/Michigan/12/2022	UXG51661.1
neuraminidase (NA)		Influenza A virus A/Michigan/12/2022	UXG51649.1
neuraminidase (NA)		Influenza A virus A/Michigan/123/2019	QCG84778.1 QDQ43485.1
neuraminidase (NA)		Influenza A virus A/Michigan/124/2019	QCG83128.1
neuraminidase (NA)		Influenza A virus A/Michigan/125/2019	QCG84789.1
neuraminidase (NA)		Influenza A virus A/Michigan/13/2021	UJS43211.1
neuraminidase (NA)		Influenza A virus A/Michigan/13/2022	UXG52918.1
neuraminidase (NA)		Influenza A virus A/Michigan/13/2022	UXG51673.1
neuraminidase (NA)		Influenza A virus A/Michigan/14/2020	QIV19906.1
neuraminidase (NA)		Influenza A virus A/Michigan/14/2021	UJS43235.1
neuraminidase (NA)		Influenza A virus A/Michigan/14/2022	UYL15685.1
neuraminidase (NA)		Influenza A virus A/Michigan/14/2022	UYL65714.1
neuraminidase (NA)		Influenza A virus A/Michigan/15/2020	QIV14482.1
neuraminidase (NA)		Influenza A virus A/Michigan/15/2021	UJS43259.1
neuraminidase (NA)		Influenza A virus A/Michigan/15/2022	UYL65726.1
neuraminidase (NA)		Influenza A virus A/Michigan/15/2022	UYL67979.1
neuraminidase (NA)		Influenza A virus A/Michigan/156/2020	QKM75761.1
neuraminidase (NA)		Influenza A virus A/Michigan/157/2020	QKM75989.1
neuraminidase (NA)		Influenza A virus A/Michigan/158/2020	QKM75772.1
neuraminidase (NA)		Influenza A virus A/Michigan/159/2020	QKM75783.1
neuraminidase (NA)		Influenza A virus A/Michigan/16/2020	QIV14493.1
neuraminidase (NA)		Influenza A virus A/Michigan/16/2021	ULD18049.1 ULE39304.1
neuraminidase (NA)		Influenza A virus A/Michigan/16/2021	UYL82458.1
neuraminidase (NA)		Influenza A virus A/Michigan/16/2021	UYL67991.1
neuraminidase (NA)		Influenza A virus A/Michigan/16/2022	UYL15697.1
neuraminidase (NA)		Influenza A virus A/Michigan/16/2022	UYL68003.1
neuraminidase (NA)		Influenza A virus A/Michigan/160/2020	QKM75794.1
neuraminidase (NA)		Influenza A virus A/Michigan/17/2020	QIZ32570.1
neuraminidase (NA)		Influenza A virus A/Michigan/17/2021	ULD18061.1 ULE39316.1
neuraminidase (NA)		Influenza A virus A/Michigan/17/2021	UYL68015.1
neuraminidase (NA)		Influenza A virus A/Michigan/17/2021	UYL82470.1
neuraminidase (NA)		Influenza A virus A/Michigan/17/2022	UYL15709.1
neuraminidase (NA)		Influenza A virus A/Michigan/17/2022	UYL67554.1
neuraminidase (NA)		Influenza A virus A/Michigan/173/2020	QSQ28647.1 QTF12999.1
neuraminidase (NA)		Influenza A virus A/Michigan/173/2020	UZN91414.1
neuraminidase (NA)		Influenza A virus A/Michigan/18/2020	QJA11412.1 QJP02900.1
neuraminidase (NA)		Influenza A virus A/Michigan/18/2021	ULD18073.1 ULE39328.1
neuraminidase (NA)		Influenza A virus A/Michigan/18/2021	UYL82482.1
neuraminidase (NA)		Influenza A virus A/Michigan/18/2021	UYL68027.1
neuraminidase (NA)		Influenza A virus A/Michigan/18/2022	UYL15721.1
neuraminidase (NA)		Influenza A virus A/Michigan/18/2022	UYL68039.1
neuraminidase (NA)		Influenza A virus A/Michigan/19/2018	AVP03653.1
neuraminidase (NA)		Influenza A virus A/Michigan/19/2020	QIZ32577.1
neuraminidase (NA)		Influenza A virus A/Michigan/19/2021	ULE38408.1 UPP03871.1 UPP03882.1
neuraminidase (NA)		Influenza A virus A/Michigan/19/2022	UYL15733.1
neuraminidase (NA)		Influenza A virus A/Michigan/19/2022	UYL68051.1
neuraminidase (NA)		Influenza A virus A/Michigan/20/2018	AVP03500.1
neuraminidase (NA)		Influenza A virus A/Michigan/20/2021	ULE39340.1
neuraminidase (NA)		Influenza A virus A/Michigan/20/2021	UYL82494.1
neuraminidase (NA)		Influenza A virus A/Michigan/20/2021	UYN13165.1
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