Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3409/2020	WCI30579.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3536/2020	WCI30578.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3537/2020	WCI30577.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3575/2020	WCI30574.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3592/2020	WCI30585.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3598/2020	WCI30565.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3627/2020	WCI30573.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3918/2020	WCI30572.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3941/2020	WCI30571.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3954/2020	WCI30570.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN3961/2020	WCI30569.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4128/2020	WCI30567.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4147/2020	WCI30575.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4154/2020	WCI30568.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4181/2020	WCI30566.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4217/2020	UYS78463.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4374/2020	UYS78465.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4381/2020	UYS78466.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4387/2020	WCI30562.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4393/2020	WCI30563.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4396/2020	WCI30564.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4451/2020	UYS78458.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4739/2020	WCI30560.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4760/2020	WCI30559.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN4773/2020	WCI30558.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5206/2020	UYS78459.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5250/2020	UYS78467.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5252/2020	WCI30557.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5254/2020	WCI30556.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5257/2020	UYS78460.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5260/2020	UYS78461.1
neuraminidase (NA)		Influenza A virus A/Karnataka/MIVAN5432/2020	UYS78462.1
neuraminidase (NA)		Influenza A virus A/Kazakhstan/A_Almaty_05_2018_H1N1_segment_6/2018	ULE73295.1
neuraminidase (NA)		Influenza A virus A/Kazakhstan/A_ZKO_41_19_H1N1_segment_6/2019	QWZ18909.1
neuraminidase (NA)		Influenza A virus A/Kazakhstan/Influenza_6327/2014	QCA40749.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0011/2018	QTJ07013.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0012/2018	QTJ06954.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0013/2018	QTJ07024.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0014/2018	QTJ07045.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0017/2019	QTJ06973.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0018/2019	QTJ06982.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0020/2019	QTJ06770.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0022/2019	QTJ06997.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0024/2019	QTJ06916.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0025/2019	QTJ06990.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0026/2019	QTJ06891.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0027/2019	QTJ06950.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0028/2019	QTJ06940.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0033/2019	QTJ06929.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0036/2019	QTJ07037.1
neuraminidase (NA)		Influenza A virus A/Keelung/R0037/2019	QTJ06898.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C20137/2016	AXF49590.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C21939/2017	UZU89125.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C25097/2017	UZU88885.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C27585/2017	AXF49594.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C27733/2017	AXF49615.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C28937/2017	UZU88931.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C33646/2017	UZU89449.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C35511/2017	AYV75026.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C35523/2017	AYV75033.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C38396/2018	UZU89496.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C38401/2018	UZU89366.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C39002/2018	UZU88955.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C41104/2018	UZU89354.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C41186/2018	UZU89227.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C41225/2018	UZU89150.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C42093/2018	UZU89344.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C42985/2018	UZU89442.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C8594/2016	AXF49619.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C8595/2016	AXF49631.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C8599/2016	AXF49643.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C8602/2016	AXF49662.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C8609/2016	AXF49670.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Chile/C8939/2016	AXF49684.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Delaware Bay/441/2018	AZV03308.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Delaware Bay/559/2008	AXM92620.1
neuraminidase (NA)		Influenza A virus A/kelp gull/Nuble/234619-1/2023	WPS70408.1
neuraminidase (NA)		Influenza A virus A/kelp gull/OHiggins/235977-1/2023	WPS70047.1
neuraminidase (NA)		Influenza A virus A/Kelp gull/Peru/M8/2019	UEE12805.1
neuraminidase (NA)		Influenza A virus A/kelpgull/Chile/C24014/2017	UZU89091.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2018	AVP06980.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2019	QBM03709.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2020	QIQ44952.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2021	ULE39136.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2021	UYL82314.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2022	UPP05928.1
neuraminidase (NA)		Influenza A virus A/Kentucky/01/2022	UXG52668.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2018	AVP08783.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2019	QBS21355.1 QCG84615.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2020	QMX87472.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2021	ULE39148.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2021	UYL82326.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2021	UYN13033.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2022	UXG50382.1
neuraminidase (NA)		Influenza A virus A/Kentucky/02/2022	UYL67931.1
neuraminidase (NA)		Influenza A virus A/Kentucky/03/2018	AVP06992.1 AXF92766.1
neuraminidase (NA)		Influenza A virus A/Kentucky/03/2019	QBS21367.1 QCG84627.1
neuraminidase (NA)		Influenza A virus A/Kentucky/03/2020	QIV14405.1
neuraminidase (NA)		Influenza A virus A/Kentucky/03/2021	ULE39160.1
neuraminidase (NA)		Influenza A virus A/Kentucky/03/2021	UYL82338.1
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