Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/jungle crow/Iwate/0303I003/2022	BDO24192.1
neuraminidase (NA)		Influenza A virus A/jungle crow/Iwate/0304I001/2022	BDO24214.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS2-56/2012	BBF41011.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS3-164/2013	BBF40949.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS3-243/2013	BBF40945.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS3-360/2013	BBF40934.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS4-371/2014	BBF41183.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS6-84/2016	BBF41212.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-115/2016	BBF41105.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-14/2016	BBF41110.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-144/2016	BBF41108.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-147/2016	BBF41109.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-197/2016	BBF41120.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-22/2016	BBF41125.1
neuraminidase (NA)		Influenza A virus A/Kagawa/DS7-69/2016	BBF41160.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS2-112/2012	BBF41019.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS2-209/2012	BBF40991.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS2-374/2012	BBF41016.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS3-271/2013	BBF40976.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS3-272/2013	BBF40941.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS3-454/2013	BBF40936.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS3-531/2013	BBF40979.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS4-503/2014	BBF41038.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS5-448/2015	BBF41068.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS5-542/2015	BBF41077.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS6-349/2016	BBF41204.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS6-513/2016	BBF41209.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS6-524/2016	BBF41096.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS6-528/2016	BBF41210.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS7-167/2016	BBF41117.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS7-517/2017	BBF41164.1
neuraminidase (NA)		Influenza A virus A/Kanagawa/DS7-522/2017	BBF41170.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2018	AVP08759.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2019	QBL90689.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2020	QIJ24411.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2021	ULD17977.1 ULE39088.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2021	UYL66788.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2021	UYL82266.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2022	UZO40283.1
neuraminidase (NA)		Influenza A virus A/Kansas/01/2022	UZO40271.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2018	AVP06944.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2019	QBM03687.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2020	QIJ24433.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2021	ULE39100.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2021	UYL82278.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2021	UYN12961.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2022	UZO40307.1
neuraminidase (NA)		Influenza A virus A/Kansas/02/2022	UZO40295.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2018	AVR40988.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2019	QBM03698.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2020	QIQ44930.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2021	ULE39112.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2021	UYL82290.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2021	UYN12973.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2022	UZO40331.1
neuraminidase (NA)		Influenza A virus A/Kansas/03/2022	UZO40319.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2018	AVR42269.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2019	QBQ86506.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2020	QIQ44941.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2021	ULE39124.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2021	UYL82302.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2021	UYN12985.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2022	UZO40355.1
neuraminidase (NA)		Influenza A virus A/Kansas/04/2022	UZO40343.1
neuraminidase (NA)		Influenza A virus A/Kansas/05/2018	AWI46328.1
neuraminidase (NA)		Influenza A virus A/Kansas/05/2019	QBS20184.1 QCW14507.1
neuraminidase (NA)		Influenza A virus A/Kansas/05/2020	QSQ62905.1
neuraminidase (NA)		Influenza A virus A/Kansas/05/2021	UYN12997.1
neuraminidase (NA)		Influenza A virus A/Kansas/05/2022	UZO40379.1
neuraminidase (NA)		Influenza A virus A/Kansas/05/2022	UZO40367.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2018	AVR41005.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2019	QBQ86519.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2020	QIV14394.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2021	UYN13009.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2021	UZO40391.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2022	UZO40403.1
neuraminidase (NA)		Influenza A virus A/Kansas/06/2022	UZO40415.1
neuraminidase (NA)		Influenza A virus A/Kansas/07/2018	AVR41010.1
neuraminidase (NA)		Influenza A virus A/Kansas/07/2019	QBS20196.1 QCW14519.1
neuraminidase (NA)		Influenza A virus A/Kansas/07/2021	UYN13021.1
neuraminidase (NA)		Influenza A virus A/Kansas/07/2021	UZO40427.1
neuraminidase (NA)		Influenza A virus A/Kansas/07/2022	UPP05785.1
neuraminidase (NA)		Influenza A virus A/Kansas/08/2018	AWQ64715.1
neuraminidase (NA)		Influenza A virus A/Kansas/08/2019	QBY34057.1
neuraminidase (NA)		Influenza A virus A/Kansas/08/2020	QIZ32417.1
neuraminidase (NA)		Influenza A virus A/Kansas/08/2022	UPP05809.1
neuraminidase (NA)		Influenza A virus A/Kansas/09/2017	AVP06957.1
neuraminidase (NA)		Influenza A virus A/Kansas/09/2018	AWQ64727.1
neuraminidase (NA)		Influenza A virus A/Kansas/09/2019	QBY32828.1 QCW14531.1
neuraminidase (NA)		Influenza A virus A/Kansas/09/2020	QKM75741.1
neuraminidase (NA)		Influenza A virus A/Kansas/09/2022	UPP05833.1 UPP05845.1
neuraminidase (NA)		Influenza A virus A/Kansas/10/2017	AVP06975.1
neuraminidase (NA)		Influenza A virus A/Kansas/10/2018	AWQ64739.1
neuraminidase (NA)		Influenza A virus A/Kansas/10/2019	QBY34068.1
neuraminidase (NA)		Influenza A virus A/Kansas/10/2020	QKM75750.1
neuraminidase (NA)		Influenza A virus A/Kansas/10/2022	UPP05857.1
neuraminidase (NA)		Influenza A virus A/Kansas/11/2018	AWQ64751.1
neuraminidase (NA)		Influenza A virus A/Kansas/11/2019	QBY32840.1 QCW14543.1
neuraminidase (NA)		Influenza A virus A/Kansas/11/2022	UPP05881.1 UPP05892.1
neuraminidase (NA)		Influenza A virus A/Kansas/12/2019	QCG84610.1 QCW14555.1
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