Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/Florida/01/2019	QBM03489.1
neuraminidase (NA)		Influenza A virus A/Florida/01/2020	QID20090.1 QIQ46172.1
neuraminidase (NA)		Influenza A virus A/Florida/01/2021	UJS42767.1
neuraminidase (NA)		Influenza A virus A/Florida/01/2022	UZO39203.1
neuraminidase (NA)		Influenza A virus A/Florida/01/2022	UZO36442.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2018	AVP06668.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2019	QBM03500.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2020	QID20763.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2020	QIQ44677.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2021	UJS42779.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2021	UXG52328.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2022	UZO39215.1
neuraminidase (NA)		Influenza A virus A/Florida/02/2022	UZO39227.1
neuraminidase (NA)		Influenza A virus A/Florida/03/2018	AVP06680.1
neuraminidase (NA)		Influenza A virus A/Florida/03/2019	QBS20972.1 QCG84303.1
neuraminidase (NA)		Influenza A virus A/Florida/03/2020	QIQ45983.1
neuraminidase (NA)		Influenza A virus A/Florida/03/2022	UZO39251.1
neuraminidase (NA)		Influenza A virus A/Florida/03/2022	UZO39239.1
neuraminidase (NA)		Influenza A virus A/Florida/04/2018	AVP08238.1
neuraminidase (NA)		Influenza A virus A/Florida/04/2019	QBM03510.1
neuraminidase (NA)		Influenza A virus A/Florida/04/2020	QIQ44690.1
neuraminidase (NA)		Influenza A virus A/Florida/04/2021	UJS42803.1
neuraminidase (NA)		Influenza A virus A/Florida/04/2022	UZO36432.1
neuraminidase (NA)		Influenza A virus A/Florida/05/2018	AWC07387.1
neuraminidase (NA)		Influenza A virus A/Florida/05/2020	QIQ44699.1
neuraminidase (NA)		Influenza A virus A/Florida/05/2021	UJS42827.1
neuraminidase (NA)		Influenza A virus A/Florida/05/2022	UPP05317.1
neuraminidase (NA)		Influenza A virus A/Florida/05/2022	UZO36511.1
neuraminidase (NA)		Influenza A virus A/Florida/06/2018	AVP08567.1
neuraminidase (NA)		Influenza A virus A/Florida/06/2019	QBS20984.1 QCW13907.1
neuraminidase (NA)		Influenza A virus A/Florida/06/2020	QIQ46184.1
neuraminidase (NA)		Influenza A virus A/Florida/06/2022	UPP04186.1
neuraminidase (NA)		Influenza A virus A/Florida/06/2022	UZO39263.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2018	AVP08574.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2019	QBP37690.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2020	QIQ44710.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2021	ULD17749.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2021	UYL15385.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2021	UYL66608.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2022	UPP05329.1
neuraminidase (NA)		Influenza A virus A/Florida/07/2022	UZO39275.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2018	AVP06704.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2019	QBP37698.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2020	QIQ44721.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2021	ULD17761.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2021	UYL15397.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2021	UYL66620.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2022	UPP05341.1
neuraminidase (NA)		Influenza A virus A/Florida/08/2022	UZO39287.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2018	AVP06716.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2019	QBP37712.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2020	QIQ44732.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2021	ULD17773.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2021	UYL15409.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2021	UYL66632.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2022	UXG52512.1
neuraminidase (NA)		Influenza A virus A/Florida/09/2022	UYL66644.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2018	AVP08585.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2019	QBP37718.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2020	QIQ46196.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2021	ULD17785.1 ULE38764.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2021	UYL65546.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2021	UYL67679.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2022	UXG52294.1
neuraminidase (NA)		Influenza A virus A/Florida/10/2022	UYL66656.1
neuraminidase (NA)		Influenza A virus A/Florida/100/2018	AZS63728.1 QBL91356.1
neuraminidase (NA)		Influenza A virus A/Florida/100/2019	QGQ57745.1
neuraminidase (NA)		Influenza A virus A/Florida/100/2022	WES76221.1
neuraminidase (NA)		Influenza A virus A/Florida/101/2018	AZS63764.1 QAU20488.1
neuraminidase (NA)		Influenza A virus A/Florida/101/2019	QGW44087.1 QHI02975.1
neuraminidase (NA)		Influenza A virus A/Florida/102/2017	AVH77207.1 AVP03441.1
neuraminidase (NA)		Influenza A virus A/Florida/102/2018	AZS65044.1
neuraminidase (NA)		Influenza A virus A/Florida/102/2019	QGQ58373.1 QLD99586.1
neuraminidase (NA)		Influenza A virus A/Florida/102/2022	WES76233.1
neuraminidase (NA)		Influenza A virus A/Florida/103/2017	AUS93786.1
neuraminidase (NA)		Influenza A virus A/Florida/103/2018	AZS65577.1
neuraminidase (NA)		Influenza A virus A/Florida/103/2019	QGW44099.1 QHI02987.1
neuraminidase (NA)		Influenza A virus A/Florida/103/2022	WES76245.1
neuraminidase (NA)		Influenza A virus A/Florida/104/2017	AUS93793.1 AVG71277.1 AVP03959.1
neuraminidase (NA)		Influenza A virus A/Florida/104/2018	QAB02292.1
neuraminidase (NA)		Influenza A virus A/Florida/104/2019	QGQ57705.1
neuraminidase (NA)		Influenza A virus A/Florida/104/2022	WES76257.1
neuraminidase (NA)		Influenza A virus A/Florida/105/2017	AUS93448.1
neuraminidase (NA)		Influenza A virus A/Florida/105/2018	QAB02204.1
neuraminidase (NA)		Influenza A virus A/Florida/105/2019	QGQ57756.1
neuraminidase (NA)		Influenza A virus A/Florida/105/2022	WES76269.1
neuraminidase (NA)		Influenza A virus A/Florida/106/2017	AVP08229.1
neuraminidase (NA)		Influenza A virus A/Florida/106/2018	QAB01874.1 QBL91368.1
neuraminidase (NA)		Influenza A virus A/Florida/106/2019	QGQ57763.1
neuraminidase (NA)		Influenza A virus A/Florida/106/2022	WES76281.1
neuraminidase (NA)		Influenza A virus A/Florida/107/2017	AVP06238.1
neuraminidase (NA)		Influenza A virus A/Florida/107/2018	QAB01851.1 QBS20989.1
neuraminidase (NA)		Influenza A virus A/Florida/107/2019	QGW44111.1 QHI02999.1
neuraminidase (NA)		Influenza A virus A/Florida/107/2022	WES76293.1
neuraminidase (NA)		Influenza A virus A/Florida/108/2017	AVP06728.1
neuraminidase (NA)		Influenza A virus A/Florida/108/2018	QAB02182.1
neuraminidase (NA)		Influenza A virus A/Florida/108/2019	QGW44123.1 QHW15022.1
neuraminidase (NA)		Influenza A virus A/Florida/108/2022	WES76305.1
neuraminidase (NA)		Influenza A virus A/Florida/109/2017	AXB52696.1
neuraminidase (NA)		Influenza A virus A/Florida/109/2018	QAB01668.1 QBL91379.1
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