Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/Delaware/34/2017	AVP06627.1
neuraminidase (NA)		Influenza A virus A/Delaware/34/2018	AYW00600.1
neuraminidase (NA)		Influenza A virus A/Delaware/34/2019	QDQ44146.1
neuraminidase (NA)		Influenza A virus A/Delaware/34/2022	UZO39007.1
neuraminidase (NA)		Influenza A virus A/Delaware/34/2022	UZO38995.1
neuraminidase (NA)		Influenza A virus A/Delaware/34/2023	WJN09274.1
neuraminidase (NA)		Influenza A virus A/Delaware/35/2018	AZS65608.1
neuraminidase (NA)		Influenza A virus A/Delaware/35/2019	QDJ94588.1
neuraminidase (NA)		Influenza A virus A/Delaware/35/2022	UZO39028.1
neuraminidase (NA)		Influenza A virus A/Delaware/35/2022	UZO39016.1
neuraminidase (NA)		Influenza A virus A/Delaware/36/2018	AZJ60857.1 QAU20817.1
neuraminidase (NA)		Influenza A virus A/Delaware/36/2019	QDQ44158.1
neuraminidase (NA)		Influenza A virus A/Delaware/36/2022	UZO39040.1
neuraminidase (NA)		Influenza A virus A/Delaware/36/2022	UZO39052.1
neuraminidase (NA)		Influenza A virus A/Delaware/36/2023	WJN09286.1
neuraminidase (NA)		Influenza A virus A/Delaware/37/2019	QDJ94599.1 QFO38620.1
neuraminidase (NA)		Influenza A virus A/Delaware/37/2022	WBQ77228.1
neuraminidase (NA)		Influenza A virus A/Delaware/37/2022	WBQ77216.1
neuraminidase (NA)		Influenza A virus A/Delaware/37/2023	WJN09298.1
neuraminidase (NA)		Influenza A virus A/Delaware/38/2018	AZS65637.1
neuraminidase (NA)		Influenza A virus A/Delaware/38/2019	QEI02074.1
neuraminidase (NA)		Influenza A virus A/Delaware/38/2022	WBQ77240.1
neuraminidase (NA)		Influenza A virus A/Delaware/38/2022	WBQ77252.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2017	AVP06639.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2018	AZS65549.1 QBF66168.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2019	QFZ87856.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2022	WBQ77264.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2022	WBQ77276.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2023	WJN09310.1
neuraminidase (NA)		Influenza A virus A/Delaware/39/2023	WJN09322.1
neuraminidase (NA)		Influenza A virus A/Delaware/40/2018	QAB01803.1 QBL91320.1
neuraminidase (NA)		Influenza A virus A/Delaware/40/2019	QEI02086.1
neuraminidase (NA)		Influenza A virus A/Delaware/40/2022	WBO07307.1
neuraminidase (NA)		Influenza A virus A/Delaware/40/2023	WJN08922.1
neuraminidase (NA)		Influenza A virus A/Delaware/41/2017	AVG71069.1
neuraminidase (NA)		Influenza A virus A/Delaware/41/2018	QAB01827.1 QBL91332.1
neuraminidase (NA)		Influenza A virus A/Delaware/41/2019	QED95055.1 QHI01844.1
neuraminidase (NA)		Influenza A virus A/Delaware/41/2022	WBQ76721.1
neuraminidase (NA)		Influenza A virus A/Delaware/41/2023	WJN09334.1
neuraminidase (NA)		Influenza A virus A/Delaware/41/2023	WJN09346.1
neuraminidase (NA)		Influenza A virus A/Delaware/42/2018	QAB02226.1 QBF66179.1
neuraminidase (NA)		Influenza A virus A/Delaware/42/2019	QED95067.1
neuraminidase (NA)		Influenza A virus A/Delaware/42/2022	WBQ77288.1
neuraminidase (NA)		Influenza A virus A/Delaware/43/2018	QAB02324.1
neuraminidase (NA)		Influenza A virus A/Delaware/43/2019	QES86915.1
neuraminidase (NA)		Influenza A virus A/Delaware/43/2022	WBQ77300.1
neuraminidase (NA)		Influenza A virus A/Delaware/43/2023	WJN09370.1
neuraminidase (NA)		Influenza A virus A/Delaware/43/2023	WJN09358.1
neuraminidase (NA)		Influenza A virus A/Delaware/44/2017	AUS93426.1
neuraminidase (NA)		Influenza A virus A/Delaware/44/2018	QAU20782.1
neuraminidase (NA)		Influenza A virus A/Delaware/44/2019	QFQ51110.1
neuraminidase (NA)		Influenza A virus A/Delaware/44/2022	WBO07594.1
neuraminidase (NA)		Influenza A virus A/Delaware/45/2017	AUS93437.1 AVH77328.1
neuraminidase (NA)		Influenza A virus A/Delaware/45/2019	QFQ51121.1
neuraminidase (NA)		Influenza A virus A/Delaware/45/2022	WBQ77312.1
neuraminidase (NA)		Influenza A virus A/Delaware/46/2017	AUS93756.1
neuraminidase (NA)		Influenza A virus A/Delaware/46/2018	QBL90021.1
neuraminidase (NA)		Influenza A virus A/Delaware/46/2018	QBS20893.1
neuraminidase (NA)		Influenza A virus A/Delaware/46/2019	QFQ51277.1 QGQ58212.1
neuraminidase (NA)		Influenza A virus A/Delaware/46/2022	WBO07605.1
neuraminidase (NA)		Influenza A virus A/Delaware/47/2017	AUS93766.1
neuraminidase (NA)		Influenza A virus A/Delaware/47/2018	QBL96510.1
neuraminidase (NA)		Influenza A virus A/Delaware/47/2019	QFZ88432.1
neuraminidase (NA)		Influenza A virus A/Delaware/47/2022	WBQ76837.1
neuraminidase (NA)		Influenza A virus A/Delaware/47/2023	WJN09382.1
neuraminidase (NA)		Influenza A virus A/Delaware/47/2023	WNS52471.1
neuraminidase (NA)		Influenza A virus A/Delaware/48/2017	AVP08308.1
neuraminidase (NA)		Influenza A virus A/Delaware/48/2018	QBL96521.1
neuraminidase (NA)		Influenza A virus A/Delaware/48/2019	QGQ58361.1
neuraminidase (NA)		Influenza A virus A/Delaware/48/2022	WBQ77324.1
neuraminidase (NA)		Influenza A virus A/Delaware/48/2023	WNS52495.1
neuraminidase (NA)		Influenza A virus A/Delaware/48/2023	WNS52483.1
neuraminidase (NA)		Influenza A virus A/Delaware/49/2017	AVP06644.1
neuraminidase (NA)		Influenza A virus A/Delaware/49/2018	QBF65927.1
neuraminidase (NA)		Influenza A virus A/Delaware/49/2019	QGW44075.1 QHN71590.1
neuraminidase (NA)		Influenza A virus A/Delaware/49/2022	WBO07616.1
neuraminidase (NA)		Influenza A virus A/Delaware/49/2023	WNS52519.1
neuraminidase (NA)		Influenza A virus A/Delaware/49/2023	WNS52507.1
neuraminidase (NA)		Influenza A virus A/Delaware/50/2017	AVP08276.1
neuraminidase (NA)		Influenza A virus A/Delaware/50/2018	QBF65569.1 QBS20905.1
neuraminidase (NA)		Influenza A virus A/Delaware/50/2019	QHN72346.1 QIA57857.1
neuraminidase (NA)		Influenza A virus A/Delaware/50/2022	WBO07627.1
neuraminidase (NA)		Influenza A virus A/Delaware/50/2023	WNS52287.1
neuraminidase (NA)		Influenza A virus A/Delaware/50/2023	WNS52297.1
neuraminidase (NA)		Influenza A virus A/Delaware/51/2018	QBF65581.1 QBS20917.1
neuraminidase (NA)		Influenza A virus A/Delaware/51/2019	QHN72675.1 QIA57870.1
neuraminidase (NA)		Influenza A virus A/Delaware/52/2018	QBF66196.1
neuraminidase (NA)		Influenza A virus A/Delaware/52/2019	QHW14993.1 QIA55225.1
neuraminidase (NA)		Influenza A virus A/Delaware/52/2022	WBQ77336.1
neuraminidase (NA)		Influenza A virus A/Delaware/53/2019	QHX37899.1 QIA57881.1
neuraminidase (NA)		Influenza A virus A/Delaware/53/2022	WBQ77348.1
neuraminidase (NA)		Influenza A virus A/Delaware/54/2019	QHX37635.1 QIA57545.1
neuraminidase (NA)		Influenza A virus A/Delaware/55/2019	QIA57890.1 QIJ24125.1 QIV13727.1 QIZ31632.1 QJS98841.1 QRV63235.1
neuraminidase (NA)		Influenza A virus A/Delaware/56/2019	QIA57903.1 QIJ24136.1
neuraminidase (NA)		Influenza A virus A/Delaware/56/2022	WBQ74346.1
neuraminidase (NA)		Influenza A virus A/Delaware/57/2019	QIA55237.1
neuraminidase (NA)		Influenza A virus A/Delaware/58/2019	QIA55249.1 QIJ26206.1
neuraminidase (NA)		Influenza A virus A/Delaware/59/2019	QIJ26218.1
neuraminidase (NA)		Influenza A virus A/Delaware/60/2019	QIJ26230.1
neuraminidase (NA)		Influenza A virus A/Delaware/61/2022	WBQ74165.1
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